The treatment of patent ductus arteriosus in preterm infants. A review and overview of randomized trials.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Seminars in neonatology : SN

• Publication date

  2001-02-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1053/SINY.2000.0036PMID 11162286
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Hemodynamically significant PDA: An echocardiographic and clinical assessment of incidence, natural history, and outcome in very low birth weight infants maintained in negative fluid balance

  2005cited by this paper
• Low superior vena cava flow and intraventricular haemorrhage in preterm infants

  2000cited by this paper
• Short versus prolonged indomethacin therapy for patent ductus arteriosus in preterm infants.

  1999cited by this paper
• Early versus Late Selective Treatment for Patent Ductus Arteriosus in Preterm Infants with Respiratory Distress Syndrome. † 1166

  1998cited by this paper
• Ibuprofen for Early Treatment of Patent Ductus Arteriosus, a Randomized Multicenter Trial. • 1167

  1998cited by this paper
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  1997cited by this paper
• Treatment of patent ductus arteriosus with ibuprofen

  1997cited by this paper
• Early determinants of right and left ventricular output in ventilated preterm infants.

  1996cited by this paper
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  1996cited by this paper
• Neurodevelopmental outcome at 36 months' corrected age of preterm infants in the Multicenter Indomethacin Intraventricular Hemorrhage Prevention Trial.

  1996cited by this paper
• Early ibuprofen administration to prevent patent ductus arteriosus in premature newborn infants.

  1996cited by this paper
• Continuous versus multiple rapid infusions of indomethacin: effects on cerebral blood flow velocity.

  1995cited by this paper
• Longitudinal changes in the diameter of the ductus arteriosus in ventilated preterm infants: correlation with respiratory outcomes.

  1995cited by this paper
• Pulmonary effects of closure of patent ductus arteriosus in premature infants with severe respiratory distress syndrome

  1994cited by this paper
• Low-dose indomethacin therapy and extension of intraventricular hemorrhage: a multicenter randomized trial.

  1994cited by this paper
• Prevention of periventricular hemorrhage.

  1994cited by this paper
• Assessment of ductus arteriosus shunt in preterm infants supported by mechanical ventilation: effect of interatrial shunting.

  1994cited by this paper
• Low-dose indomethacin and prevention of intraventricular hemorrhage: a multicenter randomized trial.

  1994cited by this paper
• Effective care of the newborn infant

  1992cited by this paper
• Patent ductus arteriosus: how important to which babies?

  1992cited by this paper
• Fluid restriction for preventing bronchopulmonary dysplasia? Reduced fluid intake during the first weeks of life improves the outcome of low‐birth‐weight infants

  1992cited by this paper
• Effect of patency of the ductus arteriosus on blood pressure in very preterm infants.

  1992cited by this paper
• Closure of the ductus arteriosus with indomethacin in ventilated neonates with respiratory distress syndrome. Effects of pulmonary compliance and ventilation.

  1991cited by this paper
• Prolonged low dose indomethacin for persistent ductus arteriosus of prematurity.

  1991cited by this paper
• Prolonged indomethacin therapy for the prevention of recurrences of patent ductus arteriosus.

  1990cited by this paper
• Effects of indomethacin on cerebral haemodynamics in very preterm infants.

  1990cited by this paper
• Stroke Volume and Left Ventricular Output in Preterm Infants with Patent Ductus Arteriosus

  1990cited by this paper
• Indomethacin reduces the risks of severe intraventricular hemorrhage.

  1989cited by this paper
• Surgical closure of the patent ductus arteriosus in the neonatal intensive care unit.

  1989cited by this paper
• A randomized, controlled trial of very early prophylactic ligation of the ductus arteriosus in babies who weighed 1000 g or less at birth.

  1989cited by this paper
• Pulmonary function in preterm infants following treatment with intravenous indomethacin.

  1989cited by this paper
• Administration of indomethacin for the prevention of periventricular-intraventricular hemorrhage in high-risk neonates.

  1988cited by this paper
• Prophylactic indomethacin for prevention of intraventricular hemorrhage in premature infants.

  1988cited by this paper
• Auswirkungen einer Frühtherapie mit Indomethazin auf die Manifestation eines persistierenden Ductus arteriosus bei extrem untergewichtigen Frühgeborenen

  1988cited by this paper
• Randomized low-dose indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight neonates.

  1988cited by this paper
• Prophylactic Treatment of Asymptomatic Patent Ductus Arteriosus in Premature Infants With Respiratory Distress Syndrome

  1987cited by this paper
• Early Intravenous Indomethacin Prolongs Respiratory Support in Very Low Birth Weight Infants

  1987cited by this paper
• Prevention of symptomatic patent ductus arteriosus with a single dose of indomethacin.

  1987cited by this paper
• Failure of prophylactic indomethacin to improve the outcome of the very low birth weight infant.

  1987cited by this paper
• Early administration of indomethacin to preterm infants.

  1986cited by this paper
• Indomethacin therapy on the first day of life in infants with very low birth weight.

  1985cited by this paper
• Randomized indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight infants.

  1985cited by this paper
• 1488 PROPHYLACTIC INDOMETHACIN (I) FOR THE PREVENTION OF PATENT DUCTUS ARTERIOSUS (PDA)

  1985cited by this paper
• Effects of indomethacin in premature infants with patent ductus arteriosus: results of a national collaborative study.

  1983cited by this paper
• Indomethacin treatment for patent ductus arteriosus in very low birthweight infants: double blind trial.

  1983cited by this paper
• EARLY CLOSURE OF PATENT DUCTUS ARTERIOSUS WITH INDOMETHACIN IN PRETERM INFANTS WITH IDIOPATHIC RESPIRATORY DISTRESS SYNDROME

  1983cited by this paper
• Effect of patent ductus arteriosus on left ventricular output in premature infants.

  1983cited by this paper
• Surgical and medical experience with 734 premature infants with patient ductus arteriosus.

  1982cited by this paper
• Prophylactic indomethacin therapy for patent ductus arteriosus in very-low-birth-weight infants.

  1982cited by this paper
• Water balance in very low-birth-weight infants: relationship to water and sodium intake and effect on outcome.

  1982cited by this paper
• Indomethacin for Closure of Patent Ductus Arteriosus in Prematures

  1982cited by this paper
• Indomethacin treatment for symptomatic patent ductus arteriosus: a double-blind control study.

  1981cited by this paper
• Improved lung compliance following indomethacin therapy in premature infants with persistent ductus arteriosus.

  1981cited by this paper
• Intravenous indomethacin therapy in premature infants with persistent ductus arteriosus--a double-blind controlled study.

  1981cited by this paper
• Early closure of the patent ductus arteriosus in very low-birth-weight infants: a controlled trial.

  1981cited by this paper
• Lung compliance in newborns with patent ductus arteriosus before and after surgical ligation.

  1980cited by this paper
• Effect of fluid administration on the development of symptomatic patent ductus arteriosus and congestive heart failure in premature infants.

  1980cited by this paper
• Randomized trial of early closure of symptomatic patent ductus arteriosus in small preterm infants.

  1978cited by this paper
• Improved lung compliance after ligation of patent ductus arteriosus in hyaline membrane disease.

  1978cited by this paper
• Closure of the patent ductus arteriosus with ligation and indomethacin: a consecutive experience.

  1978cited by this paper

• The Relationship of Indomethacin Exposure With Efficacy and Renal Toxicity Outcomes for Preterm Infants in the Neonatal Intensive Care Unit

  2025cites this paper
• At a crossroads for early medical treatment of persistent patent ductus arteriosus in preterm infants

  2024cites this paper
• Establishing a nomogram for predicting necrotizing enterocolitis in premature infants: A retrospective multicenter cohort study.

  2024cites this paper
• Management of patent ductus arteriosus in preterm infants: Abundant literature, low certainty of evidence for clinicians.

  2024cites this paper
• Indomethacin Prophylaxis Is Associated with Reduced Risk of Intraventricular Hemorrhage in Extremely Preterm Infants Born in the Context of Amniotic Infection Syndrome

  2023cites this paper
• Patent ductus arteriosus (review): history, anatomy and physiology of a functioning duct

  2023cites this paper
• Perfusion Index as a Diagnostic Tool for Patent Ductus Arteriosus in Preterm Infants

  2022cites this paper
• Size of Patent Ductus Arteriosus and Echocardiographic Markers of Shunt Volume in Preterm Infants Based on Postnatal Age

  2021cites this paper
• The often forgotten systemic effects of ductus arteriosus: impact on decision-making and future trials

  2021cites this paper
• Association of Co-exposure of Antenatal Steroid and Prophylactic Indomethacin with Spontaneous Intestinal Perforation.

  2021cites this paper
• Patent Ductus Arteriosus Clinical Trials: Lessons Learned and Future Directions

  2021cites this paper
• Covariation of changing patent ductus arteriosus management and preterm infant outcomes in Pediatrix neonatal intensive care units

  2021cites this paper
• Prophylactic intravenous paracetamol use in extremely premature infants for patent ductus arteriosus

  2020cites this paper
• Is high platelet distribution width in the first hours of life can predict hemodynamically significant patent ductus arteriosus in preterm newborns?

  2020cites this paper
• Indomethacin dosing strategy and neonatal patent ductus arteriosus closure

  2019cites this paper
• Optimal timing of video‐assisted thoracoscopic surgery for patent ductus arteriosus in preterm infants born at ≤ 28 weeks of gestation

  2019cites this paper
• Management of patent ductus arteriosus in premature infants.

  2019cites this paper
• Intravenous paracetamol (acetaminophen) for patent ductus arteriosus closure in premature infants ≤ 32 weeks’ gestation

  2019cites this paper
• Successful Closure of Patent Ductus Arteriosus by Late Pharmacologic Treatment in a Small Preterm Infant

  2019cites this paper
• Specialist neonatal respiratory care for babies born preterm

  2019cites this paper
• Early Surgical Closure of Patent Ductus Arteriosus Improves Respiratory Outcome in Symptomatic Preterm Neonates

  2019cites this paper
• Tratamiento farmacológico del conducto arterioso permeable en recién nacidos prematuros

  2019cites this paper
• Changing patterns of patent ductus arteriosus surgical ligation in the United States.

  2018cites this paper
• Early echocardiography does not predict subsequent treatment of symptomatic patent ductus arteriosus in extremely preterm infants

  2018cites this paper
• Turkish Neonatal Society guideline on the management of patent ductus arteriosus in preterm infants

  2018cites this paper
• International perspective on management of a patent ductus arteriosus: Lessons learned.

  2018cites this paper
• The use of non-steroidal anti-inflammatory drugs for patent ductus arteriosus closure in preterm infants.

  2017cites this paper
• [Usefulness of brain natriuretic propeptide in the diagnosis and management of patent ductus arteriosus].

  2017cites this paper
• Prophylactic Indomethacin Revisited.

  2017cites this paper
• The nitric oxide synthase 2 pathway is targeted by both pro- and anti-inflammatory treatments in the immature human intestine.

  2017cites this paper
• Neonatal intensive care unit Measuring vital signs and simulating hemodynamic patterns during closure of the patent ductus arteriosus

  2017cites this paper
• Escala de riesgo Aristóteles como factor predictor de mortalidad en el cierre quirúrgico de persistencia de ductus arterioso en prematuros

  2017influential citation
• Digestive and renal complications in premature infants with patent ductus arteriosus treated with indomethacin and ibuprofen

  2017cites this paper
• Usefulness of brain natriuretic propeptide in the diagnosis and management of patent ductus arteriosus

  2017cites this paper
• Measuring vital signs and simulating hemodynamic patterns during closure of the patent ductus arteriosus

  2016cites this paper
• Cierre quirúrgico de ductus arterioso persistente en niños prematuros de menos de 1500 gramos

  2016influential citation
• Pharmacological Closure of Patent Ductus Arteriosus: Selecting the Agent and Route of Administration

  2016cites this paper
• Prevalence of patent ductus arteriosus in premature infants at the Neonatal Ward, Cipto Mangunkusumo Hospital, Jakarta

  2016cites this paper
• Persistência do canal arterial

  2015cites this paper
• Enteral paracetamol or intravenous indomethacin for closure of patent ductus arteriosus in preterm neonates: A randomized controlled trial

  2015cites this paper
• Acute Respiratory Care of the Neonate 10 Complications of Positive Pressure Ventilation

  2015cites this paper
• Patent Ductus Arteriosus Management and Outcomes in Japan and Canada: Comparison of Proactive and Selective Approaches

  2015cites this paper
• Analysis of the Heart Sounds and Murmurs of Fetuses and Preterm Infants

  2015cites this paper
• Outcome following patent ductus arteriosus ligation in premature infants: a retrospective cohort analysis

  2015cites this paper
• The Patent Ductus Arteriosus Problem: Infants Who Still Need Treatment.

  2015cites this paper
• Current controversies in the management of patent ductus arteriosus in preterm infants

  2014cites this paper
• Use of rectal ibuprofen for PDA closure in preterm neonates

  2014cites this paper
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  2014cites this paper
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  2014cites this paper
• Primary Surgical Closure Should Be Considered in Premature Neonates with Large Patent Ductus Arteriosus

  2013influential citation
• NECROTISING ENTEROCOLITIS IN INFANTS- A REVIEW

  2013cites this paper
• WHAT ARE THE ASSOCIATED FACTORS ?

  2013cites this paper
• Clinical and echocardiographic characteristics associated with the evolution of the ductus arteriosus in the neonate with birth weight lower than 1,500g

  2013cites this paper
• Functional echocardiography in staging for ductal disease severity

  2013cites this paper
• Management of patent ductus arteriosus in preterm infants: clinical judgment might be a fair option

  2013cites this paper
• Serial echocardiography in very preterm infants: a pilot randomized trial

  2013cites this paper
• Patent Ductus Arteriosus

  2013influential citation
• Assessment of PDA shunt and systemic blood flow in newborns using cardiac MRI

  2013cites this paper
• Adverse drug reactions in newborns, infants and toddlers: pediatric pharmacovigilance between present and future

  2012cites this paper
• Patent Ductus Arteriosus in Premature Neonates

  2012cites this paper
• Chapter 54 – Patent Ductus Arteriosus in the Preterm Infant

  2012cites this paper
• Clinical considerations for the pharmacologic management of patent ductus arteriosus with cyclooxygenase inhibitors in premature infants.

  2012cites this paper
• Evidence-based use of indomethacin and ibuprofen in the neonatal intensive care unit.

  2012cites this paper
• Patent ductus arteriosus: are current neonatal treatment options better or worse than no treatment at all?

  2012cites this paper
• Systematic review and network meta-analysis of intravenous ibuprofen vs. intravenous indomethacin vs. placebo in the management of clinically and/or echocardiographically important patent ductus arteriosus in preterm infants at greater than 24 hours of life

  2012influential citation
• The ductus arteriosus: a refined approach!

  2012cites this paper
• Chapter 13 – The Very Low Birth Weight Neonate with Hemodynamically Significant Ductus Arteriosus During the First Postnatal Week

  2012cites this paper
• Extremely low birth weight infants with patent ductus arteriosus: searching for the least invasiveness.

  2012cites this paper
• Therapeutic strategies, including a high surgical ligation rate, for patent ductus arteriosus closure in extremely premature infants in a North American centre.

  2012influential citation
• Morbidité à court terme : pathologie respiratoire, apnées, troubles hémodynamiques, oxygénation tissulaire, persistance du canal artériel

  2011cites this paper
• Risks and Benefits of Aggressive and Conservative Approaches to the Management of the Patent Ductus Arteriosus in Premature Infants

  2011cites this paper
• Change in Blood Pressure and Pulse Pressure in Preterm Infants After Treatment of Patent Ductus Arteriosus With Indomethacin

  2011cites this paper
• Current management of patent ductus arteriosus in premature infants among neonatologists and pediatric cardiologists

  2011cites this paper
• Risikofaktoren bei sehr untergewichtigen Frühgeborenen mit Nekrotisierender Enterokolitis in Abhängigkeit vom Alter

  2011cites this paper
• Point-of-care testing for B-type natriuretic peptide in premature neonates with patent ductus arteriosus.

  2011cites this paper
• Effect of Prophylactic Ibuprofen in Preterm Infants Less than 1,250 g in Birth Weight

  2011cites this paper
• Es la persistencia de ductus arterioso un factor de riesgo para la retinopatía del prematuro

  2011cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
• Clinical aspects of very‐low‐birthweight infants showing reopening of ductus arteriosus

  2011cites this paper
• [Is patent ductus arteriosus a risk factor for retinopathy of prematurity?].

  2011cites this paper
• Missing Data for an Evidence-Based Approach to the Treatment of a Patent Ductus Arteriosus A Small Selection of What We Do not Know Yet

  2011cites this paper
• Gastrointestinal complications associated with ibuprofen therapy for patent ductus arteriosus

  2011cites this paper
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  2011cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
• [Surgical ligation of patent ductus arteriosus in premature infants].

  2010cites this paper
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  2010cites this paper
• Tratamiento del ductus arterioso persistente en prematuros con ibuprofeno oral: metanalisis de la literatura

  2010cites this paper
• Hemodynamic Instability after Patent Ductus Arteriosus Ligation in Very Low Birth Weight Infants

  2010cites this paper
• Predictors of medical failure in the preterm patent ductus arteriosus

  2010cites this paper
• Acute lung injury in preterm newborn infants: mechanisms and management.

  2010cites this paper