The N‐myc downstream regulated gene (NDRG) family: diverse functions, multiple applications

No abstract is available for this paper.

• Publication year

  2010

• Venue

  The FASEB Journal

• Publication date

  2010-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1096/fj.09-151464PMID 20667976
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• NDRG2 induced by oxidized LDL in macrophages antagonizes growth factor productions via selectively inhibiting ERK activation.

  2010cited by this paper
• Apoptotic sensitivity of colon cancer cells to histone deacetylase inhibitors is mediated by an Sp1/Sp3-activated transcriptional program involving immediate-early gene induction.

  2010cited by this paper
• Common variants at ten loci modulate the QT interval duration in the QTSCD Study

  2009cited by this paper
• Identification of High-Risk Stage II Colorectal Tumors by Combined Analysis of the NDRG1 Gene Expression and the Depth of Tumor Invasion

  2009influential reference
• NDRG2 suppresses cell proliferation through down‐regulation of AP‐1 activity in human colon carcinoma cells

  2009cited by this paper
• NDRG2 expression decreases with tumor stages and regulates TCF/β-catenin signaling in human colon carcinoma

  2009cited by this paper
• Common variants at ten loci influence myocardial repolarization: the QTGEN consortium

  2009cited by this paper
• N-Myc downstream-regulated gene 4 (NDRG4): a candidate tumor suppressor gene and potential biomarker for colorectal cancer.

  2009cited by this paper
• N-myc downstream regulated gene 1/Cap43 suppresses tumor growth and angiogenesis of pancreatic cancer through attenuation of inhibitor of kappaB kinase beta expression.

  2009cited by this paper
• Suppression of NF-kappaB activity by NDRG2 expression attenuates the invasive potential of highly malignant tumor cells.

  2009cited by this paper
• Promoter methylation correlates with reduced NDRG2 expression in advanced colon tumour

  2009influential reference
• Bone morphogenetic protein-4 induced by NDRG2 expression inhibits MMP-9 activity in breast cancer cells.

  2009cited by this paper
• NDRG4 Is Required for Cell Cycle Progression and Survival in Glioblastoma Cells*

  2009cited by this paper
• Decreased expression of NDRG1 in glioma is related to tumor progression and survival of patients

  2009cited by this paper
• NDRG3 is an androgen regulated and prostate enriched gene that promotes in vitro and in vivo prostate cancer cell growth

  2009influential reference
• Expression of human NDRG2 by myeloid dendritic cells inhibits down‐regulation of activated leukocyte cell adhesion molecule (ALCAM) and contributes to maintenance of T cell stimulatory activity

  2008cited by this paper
• Functional and clinical evidence for NDRG2 as a candidate suppressor of liver cancer metastasis.

  2008cited by this paper
• Cap43/NDRG1/Drg-1 is a molecular target for angiogenesis and a prognostic indicator in cervical adenocarcinoma.

  2008cited by this paper
• Regulation of hypoxia-inducible genes by ETS1 transcription factor.

  2008cited by this paper
• NDRG2 is a new HIF-1 Target Gene Necessary for Hypoxia-Induced Apoptosis in A549 Cells

  2008cited by this paper
• Preclinical and clinical studies of novel breast cancer drugs targeting molecules involved in protein kinase C signaling, the putative metastasis-suppressor gene Cap43 and the Y-box binding protein-1.

  2008cited by this paper
• N-Myc down-regulated gene 1 mediates proliferation, invasion, and apoptosis of hepatocellular carcinoma cells.

  2008cited by this paper
• Expression of NDRG2 in clear cell renal cell carcinoma.

  2008cited by this paper
• Ndrg4 is required for normal myocyte proliferation during early cardiac development in zebrafish.

  2008cited by this paper
• Frequent promoter hypermethylation and transcriptional downregulation of the NDRG2 gene at 14q11.2 in primary glioblastoma

  2008cited by this paper
• The iron-regulated metastasis suppressor, Ndrg-1: identification of novel molecular targets.

  2008cited by this paper
• Differential Expression Patterns of NDRG Family Proteins in the Central Nervous System

  2008cited by this paper
• N-myc downstream regulated gene 1 (NDRG1)/Cap43 enhances portal vein invasion and intrahepatic metastasis in human hepatocellular carcinoma.

  2008cited by this paper
• UniProtKB/Swiss-Prot.

  2007cited by this paper
• Expression of NDRG2 is related to tumor progression and survival of gastric cancer patients through Fas-mediated cell death

  2007cited by this paper
• Clustal W and Clustal X version 2.0

  2007cited by this paper
• Expression of NDRG2 is down-regulated in high-risk adenomas and colorectal carcinoma

  2007cited by this paper
• Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter.

  2007cited by this paper
• Overexpression of NDRG1 is an indicator of poor prognosis in hepatocellular carcinoma

  2007cited by this paper
• SOCS1 induced by NDRG2 expression negatively regulates STAT3 activation in breast cancer cells.

  2007cited by this paper
• Identification of epigenetically silenced genes in tumor endothelial cells.

  2007cited by this paper
• Microarray analysis of normal cervix, carcinoma in situ, and invasive cervical cancer: identification of candidate genes in pathogenesis of invasion in cervical cancer

  2007cited by this paper
• (NDRG2) Stimulates Amiloride-sensitive Na+ Currents in Xenopus laevis Oocytes and Fisher Rat Thyroid Cells*

  2007cited by this paper
• Impaired Mast Cell Maturation and Degranulation and Attenuated Allergic Responses in Ndrg1-Deficient Mice1

  2007cited by this paper
• Correlation of N-myc downstream-regulated gene 1 expression with clinical outcomes of colorectal cancer patients of different race/ethnicity.

  2007cited by this paper
• Promoter methylation, mutation, and genomic deletion are involved in the decreased NDRG2 expression levels in several cancer cell lines.

  2007cited by this paper
• Array comparative genomic hybridization analysis of chromosomal imbalances and their target genes in gastrointestinal stromal tumors

  2007cited by this paper
• The Wilms' Tumor Gene 1 (WT1) Induces Expression of the N-myc Downstream Regulated Gene 2 (NDRG2)

  2007cited by this paper
• The tumor metastasis suppressor gene Drg-1 down-regulates the expression of activating transcription factor 3 in prostate cancer.

  2006cited by this paper
• Tumor growth suppression in pancreatic cancer by a putative metastasis suppressor gene Cap43/NDRG1/Drg-1 through modulation of angiogenesis.

  2006cited by this paper
• Cellular differentiation determines the expression of the hypoxia-inducible protein NDRG1 in pancreatic cancer

  2006cited by this paper
• Expression analysis of the NDRG2 gene in mouse embryonic and adult tissues

  2006cited by this paper
• Ndrg4 enhances NGF‐induced ERK activation uncoupled with Elk‐1 activation

  2006cited by this paper
• ADAMTS1, CRABP1, and NR3C1 Identified as Epigenetically Deregulated Genes in Colorectal Tumorigenesis

  2006cited by this paper
• Novel prognostic immunohistochemical biomarker panel for estrogen receptor-positive breast cancer.

  2006cited by this paper
• Decreased expression of NDRG1 is correlated with tumor progression and poor prognosis in patients with esophageal squamous cell carcinoma.

  2006cited by this paper
• The Repression of Human Differentiation-related Gene NDRG2 Expression by Myc via Miz-1-dependent Interaction with the NDRG2 Core Promoter*

  2006cited by this paper
• Identification of dysregulated genes in cutaneous squamous cell carcinoma.

  2006cited by this paper
• The Consensus Coding Sequences of Human Breast and Colorectal Cancers

  2006cited by this paper
• N-Myc Down-regulated Gene 1 Modulates the Response of Term Human Trophoblasts to Hypoxic Injury*

  2006cited by this paper
• Microarray-based identification of differentially expressed genes in hypoxic term human trophoblasts and in placental villi of pregnancies with growth restricted fetuses.

  2005cited by this paper
• Drg1 Expression in 131 Colorectal Liver Metastases: Correlation with Clinical Variables and Patient Outcomes

  2005cited by this paper
• Ndrg2 promotes neurite outgrowth of NGF-differentiated PC12 cells.

  2005cited by this paper
• Identification of differentially expressed genes in oral squamous cell carcinoma (OSCC): Overexpression of NPM, CDK1 and NDRG1 and underexpression of CHES1

  2005cited by this paper
• Glucocorticoid regulation of glial responses during hippocampal neurodegeneration and regeneration.

  2005cited by this paper
• NDRG1 interacts with APO A-I and A-II and is a functional candidate for the HDL-C QTL on 8q24.

  2005cited by this paper
• Integrative genomic analysis identifies NDRG2 as a candidate tumor suppressor gene frequently inactivated in clinically aggressive meningioma.

  2005cited by this paper
• Akt Mediates Insulin-stimulated Phosphorylation of Ndrg2

  2004cited by this paper
• Reducing agent and tunicamycin-responsive protein (RTP) mRNA expression in the placentae of normal and pre-eclamptic women.

  2004cited by this paper
• Association of N-myc downregulated gene 1 with heat-shock cognate protein 70 in mast cells.

  2004cited by this paper
• Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers

  2004cited by this paper
• N‐myc downstream‐regulated gene 1 expression in injured sciatic nerves

  2004cited by this paper
• NDRG1 Is Necessary for p53-dependent Apoptosis*

  2004cited by this paper
• PTEN Up-Regulates the Tumor Metastasis Suppressor Gene Drg-1 in Prostate and Breast Cancer

  2004cited by this paper
• Iron chelators with high antiproliferative activity up-regulate the expression of a growth inhibitory and metastasis suppressor gene: a link between iron metabolism and proliferation.

  2004cited by this paper
• N-myc downregulated gene 1 is a phosphorylated protein in mast cells.

  2004cited by this paper
• NDRG2 expression and mutation in human liver and pancreatic cancers.

  2004cited by this paper
• Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3.

  2004influential reference
• Expression analysis of the N-Myc downstream-regulated gene 1 indicates that myelinating Schwann cells are the primary disease target in hereditary motor and sensory neuropathy-Lom.

  2004cited by this paper
• Characterization and expression of three novel differentiation-related genes belong to the human NDRG gene family

  2004influential reference
• Role of the putative tumor metastasis suppressor gene Drg-1 in breast cancer progression

  2004cited by this paper
• NDRG2: a novel Alzheimer's disease associated protein.

  2004cited by this paper
• Ndrg1-Deficient Mice Exhibit a Progressive Demyelinating Disorder of Peripheral Nerves

  2004cited by this paper
• Fold prediction and comparative modeling of Bdm1: a probable alpha/beta hydrolase associated with hot water epilepsy.

  2003cited by this paper
• The Drg-1 gene suppresses tumor metastasis in prostate cancer.

  2003cited by this paper
• Expression and regulation of NDRG2 (N‐myc downstream regulated gene 2) during the differentiation of dendritic cells

  2003cited by this paper
• Identification of NDRG1 as an early inducible gene during in vitro maturation of cultured mast cells.

  2003cited by this paper
• The growth-inhibitory Ndrg1 gene is a Myc negative target in human neuroblastomas and other cell types with overexpressed N- or c-myc

  2003cited by this paper
• Identification and characterization of Xenopus NDRG1.

  2003cited by this paper
• Downregulation of Cap43 gene by von Hippel‐Lindau tumor suppressor protein in human renal cancer cells

  2003cited by this paper
• N‐Myc downstream‐regulated gene 2 (NDRG2) inhibits glioblastoma cell proliferation

  2003cited by this paper
• Fold prediction and comparative modeling of Bdm1: a probable α/β hydrolase associated with hot water epilepsy

  2003cited by this paper
• Drugs That Induce Repolarization Abnormalities Cause Bradycardia in Zebrafish

  2003cited by this paper
• Identification of a novel class in the α/β hydrolase fold superfamily: The N‐myc differentiation‐related proteins

  2002cited by this paper
• The Regulation of Hypoxic Genes by Calcium Involves c-Jun/AP-1, Which Cooperates with Hypoxia-Inducible Factor 1 in Response to Hypoxia

  2002cited by this paper
• Characterization of Rat NDRG2 (N-Myc Downstream Regulated Gene 2), a Novel Early Mineralocorticoid-specific Induced Gene*

  2002cited by this paper
• Identification of a novel class in the alpha/beta hydrolase fold superfamily: the N-myc differentiation-related proteins.

  2002cited by this paper
• Inhibition of neurite outgrowth by reduced level of NDRG4 protein in antisense transfected PC12 cells.

  2002cited by this paper
• Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart.

  2001cited by this paper
• Cloning and expression pattern of the human NDRG3 gene.

  2001cited by this paper
• Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway

  2001cited by this paper
• Drg-1 as a differentiation-related, putative metastatic suppressor gene in human colon cancer.

  2000cited by this paper
• Carcinogenic nickel induces genes involved with hypoxic stress.

  2000cited by this paper
• Hypoxia induces the expression of a 43-kDa protein (PROXY-1) in normal and malignant cells.

  2000cited by this paper
• N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom.

  2000cited by this paper

• PUM2 knockdown regulates the expression and alternative splicing of genes associated with myocardial fibrosis in H9C2 cells

  2026cites this paper
• NDRG4 overexpression is associated with reduced apoptosis after intracerebral hemorrhage via the PI3K/Akt/GSK3β signaling pathway

  2026cites this paper
• Lactylation at the metabolic-epigenetic interface in cardiovascular diseases: context-dependent mechanisms and translational roadmap.

  2026cites this paper
• High concentrations of fluorescent nanoprobes delayed Oryzias melastigma embryo hatching by modulating respiratory and metabolic pathways

  2025cites this paper
• NDRG1 as a sensor and mediator of endothelial stress: from homeostasis to inflammation and cardiovascular disease

  2025cites this paper
• Astrocytic N-myc downstream-regulated gene 2 is involved in neural injury induced by sepsis-associated encephalopathy.

  2025cites this paper
• Anti-proteolytic regulation of KRAS by USP9X/NDRG3 in KRAS-driven cancer development

  2025influential citation
• Unveiling the role of integrated stress response in pterygium: EGLN3, HSPA8, and NDRG1 as novel biomarkers and therapeutic targets.

  2025cites this paper
• Enhancement of Ndrg2 promotes hypertrophic scar fibrosis by regulating PI3K/AKT signaling pathway.

  2025cites this paper
• Cyanidin-3-glucoside upregulated NDRG2 through the PI3K/AKT pathway to alleviate EMT and ECM in renal fibrosis

  2025cites this paper
• Ndrg3 is a critical regulator of peripheral T cell maturation and homeostasis

  2025cites this paper
• Recent findings on the PD-1/PD-L1 Axis in breast cancer: Molecular mechanisms, immunotherapeutic potentials, and clinical implications.

  2025cites this paper
• NDRG1-HIF1α interaction in hypoxic signaling for pulmonary hypertension.

  2025cites this paper
• NDRG1/2 as a prognostic predictive biomarker of cervical cancer and its correlation with immune infiltration.

  2025cites this paper
• N-Myc downstream regulated gene 1b is a regulator of cell adhesion during early muscle development

  2025cites this paper
• Computational exploration of Arabidopsis thaliana N-Myc downregulated-like-1 for protein–protein interaction and phylogenetic conservation

  2025cites this paper
• NDRG1 and its family members: More than just metastasis suppressor proteins and targets of thiosemicarbazones

  2025influential citation
• Elevated N-Myc downstream-regulated gene 3 expression indicates poor survival in epithelial ovarian cancer

  2025cites this paper
• Identification of proteins related to SIS3 by iTRAQ and PRM-based comparative proteomic analysis in cisplatin-induced acute kidney injury

  2024cites this paper
• NDRGs in Breast Cancer: A Review and In Silico Analysis

  2024influential citation
• Biological and prognostic significance of NDRG2 downregulation in oral squamous cell carcinoma.

  2024cites this paper
• Elevated expression of N‐myc downstream regulated gene 1 protein in glioblastomas reflects tumor angiogenesis and poor patient prognosis

  2024cites this paper
• Mitochondrial ferritin upregulation by deferiprone reduced neuronal ferroptosis and improved neurological deficits via NDRG1/Yap pathway in a neonatal rat model of germinal matrix hemorrhage

  2024cites this paper
• Regulatory role of N-myc downregulated genes in amelogenesis in rats

  2024cites this paper
• Lactate and lactylation in cardiovascular diseases: current progress and future perspectives.

  2024cites this paper
• NDRG2 acts as a negative regulator of the progression of small-cell lung cancer through the modulation of the PTEN-AKT-mTOR signalling cascade.

  2024cites this paper
• Research progress and applications of epigenetic biomarkers in cancer

  2024cites this paper
• Novel Diagnostic Biomarkers Related to Necroptosis and Immune Infiltration in Coronary Heart Disease

  2024cites this paper
• Clinical role of NDRG2-based methylation status on survival pattern of glioblastoma

  2024cites this paper
• Alpha-ketoglutarate-dependent enzymes in breast cancer and therapeutic implications.

  2023cites this paper
• The potential role of miRNAs in the pathogenesis of adrenocortical carcinoma - A focus on signaling pathways interplay.

  2023cites this paper
• The Myc Family and the Metastasis Suppressor NDRG1: Targeting Key Molecular Interactions with Innovative Therapeutics

  2023cites this paper
• Anticancer Effect of E26 Transformation-Specific Homologous Factor through the Induction of Senescence and the Inhibition of Epithelial–Mesenchymal Transition in Triple-Negative Breast Cancer Cells

  2023cites this paper
• Oxygen-Generating Biomaterials for Translational Bone Regenerative Engineering.

  2023cites this paper
• Irrespective of Plaque Activity, Multiple Sclerosis Brain Periplaques Exhibit Alterations of Myelin Genes and a TGF-Beta Signature

  2022cites this paper
• The Function of N-Myc Downstream-Regulated Gene 2 (NDRG2) as a Negative Regulator in Tumor Cell Metastasis

  2022cites this paper
• Looking at Mountains: Role of Sustained Hypoxia in Regulating Bone Mineral Homeostasis in Relation to Wnt Pathway and Estrogen

  2022cites this paper
• NDRG1 is being investigated as a possible bladder cancer biomarker in the Iraqi population.

  2022cites this paper
• The molecular activity of cannabidiol in the regulation of Nrf2 system interacting with NF-κB pathway under oxidative stress

  2022cites this paper
• Echocardiography phenotyping in murine genetic reference population of BXD strains reveals significant eQTLs associated with cardiac function and morphology.

  2022cites this paper
• Supplementation with Tex261 provides a possible preventive treatment for hypoxic pulmonary artery hypertension

  2022cites this paper
• Environmental oxygen affects ex vivo growth and proliferation of mesenchymal progenitors by modulating mitogen-activated protein kinase and mammalian target of rapamycin signaling.

  2022cites this paper
• MiR-483 Promotes Colorectal Cancer Cell Biological Progression by Directly Targeting NDRG2 through Regulation of the PI3K/AKT Signaling Pathway and Epithelial-to-Mesenchymal Transition

  2022cites this paper
• EZH2 regulates the balance between osteoclast and osteoblast differentiation to inhibit arthritis-induced bone destruction

  2022cites this paper
• DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancer.

  2022cites this paper
• Expression and clinicopathological significance of glucocorticoid receptor, SGK1, and NDRG1 in hormone-naïve prostate carcinoma

  2022cites this paper
• A Tumor Suppressor Gene, N-myc Downstream-Regulated Gene 1 (NDRG1), in Gliomas and Glioblastomas

  2022cites this paper
• A splice altering variant in NDRG1 gene causes Charcot-Marie-Tooth disease, type 4D

  2022cites this paper
• Chromothripsis is a frequent event and underlies typical genetic changes in early T-cell precursor lymphoblastic leukemia in adults

  2022cites this paper
• Prognostic and biological role of the N-Myc downstream-regulated gene family in hepatocellular carcinoma

  2022cites this paper
• Clinical Diagnostic and Prognostic Potential of NDRG1 and NDRG2 in Hepatocellular Carcinoma Patients

  2022cites this paper
• NDRG1 Signaling Is Essential for Endothelial Inflammation and Vascular Remodeling

  2022cites this paper
• Glycogen Storage Disease Phenotypes Accompanying the Perturbation of the Methionine Cycle in NDRG3-Deficient Mouse Livers

  2022cites this paper
• Lactate attenuates astrocytic inflammation by inhibiting ubiquitination and degradation of NDRG2 under oxygen–glucose deprivation conditions

  2022cites this paper
• NDRG4 Alleviates Myocardial Infarction-Induced Apoptosis through the JAK2/STAT3 Pathway

  2022cites this paper
• NDRG1 enhances the sensitivity of cetuximab by modulating EGFR trafficking in colorectal cancer

  2021cites this paper
• N-myc downstream regulated gene 1 (ndrg1) functions as a molecular switch for cellular adaptation to hypoxia

  2021influential citation
• Differential expression and hypoxia‐mediated regulation of the N‐myc downstream regulated gene family

  2021cites this paper
• The Role of N-myc Downstream-Regulated Gene Family in Glioma Based on Bioinformatics Analysis

  2021cites this paper
• miRNA Clusters with Up-Regulated Expression in Colorectal Cancer

  2021cites this paper
• Stable Epigenetic Programming of Effector and Central Memory CD4 T Cells Occurs Within 7 Days of Antigen Exposure In Vivo

  2021cites this paper
• Experimental study of the effects of hypoxia simulator on osteointegration of titanium prosthesis in osteoporotic rats

  2021cites this paper
• Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2

  2021cites this paper
• N-myc Downstream-Regulated Gene 2 (NDRG2) Function as a Positive Regulator of Apoptosis: A New Insight into NDRG2 as a Tumor Suppressor

  2021cites this paper
• Radiation-induced gastrointestinal syndrome is alleviated in NDRG2-deficient mice.

  2021cites this paper
• NDRG1 regulates osteosarcoma cells via mediating the mitochondrial function and CSCs differentiation

  2021cites this paper
• ‘The long tail of Covid-19’ - The detection of a prolonged inflammatory response after a SARS-CoV-2 infection in asymptomatic and mildly affected patients

  2021cites this paper
• Key genes and drug delivery systems to improve the efficiency of chemotherapy

  2021cites this paper
• NDRG2 Expression in Breast Cancer Cells Downregulates PD-L1 Expression and Restores T Cell Proliferation in Tumor-Coculture

  2021cites this paper
• LDHA mediated degradation of extracellular matrix is a potential target for the treatment of aortic dissection.

  2021cites this paper
• Lipid Droplets Are Beneficial for Rabies Virus Replication by Facilitating Viral Budding

  2021cites this paper
• Siderophores for medical applications: imaging, sensors, and therapeutics.

  2021cites this paper
• N‐myc downstream regulated family member 1 (NDRG1) is enriched in myelinating oligodendrocytes and impacts myelin degradation in response to demyelination

  2021cites this paper
• Molecular mechanisms of neurodegeneration in neurodegenerative diseases

  2021cites this paper
• Regulation of tumor-associated macrophage (TAM) differentiation by NDRG2 expression in breast cancer cells

  2021cites this paper
• Proteogenomics of glioblastoma associates molecular patterns with survival

  2020cites this paper
• Extracellular Vesicles as Potential Prognostic Markers of Lymphatic Dysfunction

  2020cites this paper
• Pulsed SILAM Reveals In Vivo Dynamics of Murine Brain Protein Translation

  2020cites this paper
• Positive association of rs1049694 allele G located in NDRG1 with the incidence of gastric cancer and metastasis

  2020cites this paper
• NDRG2 gene expression pattern in ovarian cancer and its specific roles in inhibiting cancer cell proliferation and suppressing cancer cell apoptosis

  2020cites this paper
• Merkel Cell Polyomavirus and Merkel Cell Carcinoma

  2020cites this paper
• NDRG4 Alleviates Aβ1–40 Induction of SH-SY5Y Cell Injury via Activation of BDNF-Inducing Signalling Pathways

  2020cites this paper
• Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs

  2020cites this paper
• MiR-433 regulates myocardial ischemia reperfusion injury by targeting NDRG4 via the PI3K/Akt pathway.

  2020cites this paper
• Hypoxia Regulation of ndrgs

  2020cites this paper
• Relationship between miR-375 regulating Ndrg2/IL-6/STAT3 signaling pathway and diabetic retinopathy in rats.

  2020cites this paper
• Hypermethylation-mediated silencing of NDRG4 promotes pancreatic ductal adenocarcinoma by regulating mitochondrial function

  2020cites this paper
• Abnormal social behavior and altered gene expression in mice lacking NDRG2.

  2020cites this paper
• Pathophysiological significance of N‐myc downstream‐regulated gene 2 in cancer development through protein phosphatase 2A phosphorylation regulation

  2020cites this paper
• A loss‐of‐function mutation p.T256M in NDRG4 is implicated in the pathogenesis of pulmonary atresia with ventricular septal defect (PA/VSD) and tetralogy of Fallot (TOF)

  2020cites this paper
• Roles of N-myc downstream-regulated gene 2 in the central nervous system: molecular basis and relevance to pathophysiology

  2020cites this paper
• iTRAQ-based proteomic analysis of the interaction of A549 human lung epithelial cells with Aspergillus fumigatus conidia

  2020cites this paper
• miR-2382-5p Regulates Lipid Metabolism by Targeting NDRG2 in Mammary Epithelial Cells of Dairy Cattle

  2020cites this paper
• Pharmacological targeting and the diverse functions of the metastasis suppressor, NDRG1, in cancer.

  2020cites this paper
• Serum and Glucocorticoid-Inducible Kinase 1 (SGK1) in NSCLC Therapy

  2020cites this paper
• The Emerging Role of MicroRNAs in Regulating the Drug Response of Cholangiocarcinoma

  2020cites this paper
• Lactate Dehydrogenase A Governs Cardiac Hypertrophic Growth in Response to Hemodynamic Stress

  2020cites this paper
• N-MYC Downstream Regulated Gene 4 (NDRG4), a Frequent Downregulated Gene through DNA Hypermethylation, plays a Tumor Suppressive Role in Esophageal Adenocarcinoma

  2020cites this paper
• Astrocytic NDRG2 is critical in the maintenance of neuropathic pain.

  2020cites this paper
• Metastatic Melanoma Patient–Derived Xenografts Respond to MDM2 Inhibition as a Single Agent or in Combination with BRAF/MEK Inhibition

  2020cites this paper