2S protein Ara h 7.0201 has unique epitopes compared to other Ara h 7 isoforms and is comparable to 2S proteins Ara h 2 and 6 in basophil degranulation capacity

S. Hayen,Anna M. Ehlers,C. D. H. Jager,Johan Garssen,E. F. Knol,A. Knulst,W. Suer,L. Willemsen,Henny G. Otten

Published 2018 in Clinical and Experimental Allergy

ABSTRACT

Screening for specific IgE against 2S albumin proteins Ara h 2 and 6 has good positive predictive value in diagnosing peanut allergy. From the third 2S member Ara h 7, 3 isoforms have been identified. Their allergenicity has not been elucidated.

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