[Biochemistry of asparaginase. Properties of the asparaginase system and biological activity].

No abstract is available for this paper.

• Publication year

  1969

• Venue

  Pathologie et biologie

• Publication date

  1969-10-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  PMID 4907926
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The toxicity of Escherichia coli L-asparaginase.

  1969cited by this paper
• Purification and properties of asparaginase from escherichia coli B.

  1969cited by this paper
• Regeneration, tumor, dietary, and L-asparaginase effects on asparagine biosynthesis in rat liver.

  1969cited by this paper
• L-asparaginase and blastogenesis.

  1969cited by this paper
• Guinea pig asparagine synthetase.

  1969cited by this paper
• Response to highly purified L-asparaginase during therapy of acute leukemia.

  1969cited by this paper
• The asparagine synthetase of Escherichia coli. II. Studies on mechanism.

  1969cited by this paper
• The influence of human serum on the anti-tumour activity of two L-asparaginases.

  1969cited by this paper
• Absence of L-asparaginase in placenta.

  1969cited by this paper
• Asparagine Synthetase Activity in Malignant and Non-malignant Human Kidney and Prostate Specimens

  1969cited by this paper
• The effect of animal sera and bovine serum albumin on L-asparaginase determination in vitro.

  1969cited by this paper
• Studies on the asparagine requirement of the Jensen sarcoma and the derivation of its nutritional variant.

  1969cited by this paper
• L-asparaginase: inhibition of endogenous RNA polymerase activity in regenerating liver.

  1969cited by this paper
• Studies on the Aspartic Acid “Sparing Effect” on the Nutritional Requirement of L-Asparagine for Tumors in Vitro

  1969cited by this paper
• Inhibitory activity of L-asparaginase from Mycobacterium tuberculosis on Yoshida ascites sarcoma in rats.

  1969cited by this paper
• Hypoalbuminemic and hypocholesterolemic effect of L-asparaginase (NSC-109,229) treatment in man--a preliminary report.

  1969cited by this paper
• Hepatic Lipidosis Associated with l-Asparaginase Treatment∗

  1969cited by this paper
• The asparagine synthetase of Escherhic coli. I. Biosynthetic role of the enzyme, purification, and characterization of the reaction products.

  1969cited by this paper
• Asparagine synthetase in asparaginase resistant and susceptible mouse lymphomas.

  1968cited by this paper
• Studies on asparagine synthesis and utilization in seedlings.

  1968cited by this paper
• [Asparagine].

  1968cited by this paper
• A new L-asparaginase with antitumour activity?

  1968cited by this paper
• Embryotoxic Effect of L-Asparaginase

  1968cited by this paper
• Role of the LDH-elevating Virus in Leukaemia Therapy by Asparaginase

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• Effects of Guinea-pig Serum on the Walker 256 Carcinosarcoma

  1968cited by this paper
• L-Asparaginase Activity in Human and Animal Sera

  1968cited by this paper
• 5-Diazo-4-Oxo-L-Norvaline: Reactive Asparagine Analog with Biological Specificity

  1968cited by this paper
• STUDIES ON THE MECHANISM OF TUMOR INHIBITION BY L-ASPARAGINASE

  1968cited by this paper
• Production of l-Asparaginase II by Escherichia coli

  1968cited by this paper
• Factors which may influence the effectiveness of L-asparaginases as tumor inhibitors.

  1968cited by this paper
• New Procedures for Purification of l-Asparaginase with High Yield from Escherichia coli

  1968cited by this paper
• The effects of L-asparaginase on the amino acid incorporation of mouse lymphoid tumors.

  1968cited by this paper
• Equilibrium constant for the reversible deamination of aspartic acid.

  1968cited by this paper
• L-asparaginase: the evolution of a new tumor inhibitory agent.

  1968cited by this paper
• Changes in ribonuclease activities in P1798 lymphosarcoma after asparaginase treatment.

  1968cited by this paper
• Asparagine Synthetase Activity of Mouse Leukemias

  1968cited by this paper
• Fatty livers, adenosine triphosphate and asparagine.

  1968cited by this paper
• Inhibition of HeLa cell cultures by preparations of Escherichia coli L-asparaginase.

  1968cited by this paper
• Antitumor activity and other biologic properties of L-asparaginase (NSC-109229)-a review.

  1968cited by this paper
• L-asparagine and leukemia.

  1968cited by this paper
• L-asparaginases from Mycobacterium tuberculosis strains H37Rv and H37Ra.

  1968cited by this paper
• Asparagine biosynthesis by the Novikoff Hepatoma isolation, purification, property, and mechanism studies of the enzyme system.

  1968cited by this paper
• Localization of the two-L-asparaginases in anaerobically grown Escherichia coli.

  1967cited by this paper
• Enzymes in cancer. Asparaginase from chicken liver.

  1967cited by this paper
• Inhibition of leukemias in man by L-asparaginase.

  1967cited by this paper
• Asparagine synthesis in the chick embryo liver.

  1967cited by this paper
• L-asparaginase therapy for leukemia and other malignant neoplasms. Remission in human leukemia.

  1967cited by this paper
• Immunity to the 6C3HED ascites tumor following treatment of tumor-bearing mice with Escherichia coli L-asparaginase.

  1967cited by this paper
• Partial purification and antilymphoma activity of Serratia marcescens L-asparaginase.

  1967cited by this paper
• L-Asparaginase:Toxicity to Normal and Leukemic Human Lymphocytes

  1967cited by this paper
• L-asparagine amidohhdrolase (E. C. 3.5.1.1.) in a commercial preparation of Escherichia coli ATCC 11246. Some properties of the enzyme and its possible use in the determination of l-asparagine.

  1967cited by this paper
• SUPPRESSION OF MURINE LEUKEMIAS BY L-ASPARAGINASE

  1967cited by this paper
• Differences in the production of L-asparagine in asparaginase-sensitive and resistant lymphoma cells.

  1967cited by this paper
• Two L-asparaginases from Escherichia coli B. Their separation, purification, and antitumor activity.

  1967cited by this paper
• A Comparison of Concurrent and Delayed Tests for Antitumor Activity of L-Asparaginase.∗

  1967cited by this paper
• L-asparagine biosynthesis by nutritional variants of the Jensen sarcoma.

  1967cited by this paper
• Toxicity of L-Asparaginase to Resistant and Susceptible Lymphoma Cells in vitro∗

  1967cited by this paper
• L-Asparaginase: Inhibition of Early Mitosis in Regenerating Rat Liver

  1967cited by this paper
• Two L-asparaginases from E. coli and their action against tumors.

  1966cited by this paper
• Studies on the mechanism of inhibition of tumor growth by the enzyme glutaminase.

  1966cited by this paper
• The incorporation of l-asparagine-14C by lymphoma 6C3HED cells: its inhibition by guinea pig serum.

  1966cited by this paper
• The antitumor activity of Escherichia coli L-asparaginase.

  1966cited by this paper
• The population-dependent requirement by cultured mammalian cells for metabolites which they can synthesize. II. Glutamic acid and glutamine; aspartic acid and asparagine.

  1966cited by this paper
• Antagonism of Purified Asparaginase from Guinea Pig Serum toward Lymphoma

  1966cited by this paper
• Response of Intracerebral Gardner Lymphoma to Guinea Pig L-Asparaginase and Escherichia coli L-Asparaginase.∗

  1966cited by this paper
• Purification and properties of guinea pig serum asparaginase.

  1966cited by this paper
• In vivo and in vitro effects of the L-asparaginase fraction of guinea pig serum on the 6C3HED ascites lymphosarcoma.

  1966cited by this paper
• Toxic and antineoplastic effects of l‐asparaginase: Study of mice with lymphoma and normal monkeys and report on a child with leukemia

  1966cited by this paper
• Guinea Pig Serum Inhibitory Factor and Asparaginase Activity.∗

  1966cited by this paper
• Antilymphoma activity of L-asparaginase in vivo: clearance rates of enzyme preparations from guinea pig serum and yeast in relation to their effect on tumor growth.

  1965cited by this paper
• A Metabolic Difference Between Two Lines of Lymphoma 6C3HED Cells in Relation to Asparagine.∗

  1965cited by this paper
• GUINEA PIG SERUM AND LIVER ASPARAGINASES. PURIFICATION AND ANTITUMOR ACTIVITY.

  1965cited by this paper
• COMPARATIVE METABOLIC STUDIES ON NORMAL AND NEOPLASTIC RAT LIVER. 3. CHANGES IN THE COMPOSITION OF THE CULTURE MEDIUM WITH REGARD TO ARGININE, GLUTAMINE, GLUTAMIC ACID AND ALANINE DURING CULTIVATION OF NORMAL, NEOPLASTIC, NEWBORN AND REGENERATING LIVER.

  1964cited by this paper
• TUMOR INHIBITORY EFFECT OF L-ASPARAGINASE FROM ESCHERICHIA COLI.

  1964cited by this paper
• EFFECT OF ADMINISTRATION OF THE ENZYME GLUTAMINASE ON THE GROWTH OF CANCER CELLS.

  1964cited by this paper
• ASPARAGINASE IN THE BRAIN OF GUINEA PIG IN EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS

  1964cited by this paper
• PURIFICATION AND PROPERTIES OF THE ASPARAGINE SYNTHETASE OF STREPTOCOCCUS BOVIS.

  1964cited by this paper
• AN ENZYMIC MICROMETHOD FOR DETERMINATION OF GLUTAMINE AND ASPARAGINE IN BLOOD.

  1963cited by this paper
• EVIDENCE THAT THE L-ASPARAGINASE OF GUINEA PIG SERUM IS RESPONSIBLE FOR ITS ANTILYMPHOMA EFFECTS

  1963cited by this paper
• Inhibitory Effect of Guinea Pig Serum on a Number of New Leukæmias in Mice

  1963cited by this paper
• Leukæmia-inhibiting Properties and L-Asparaginase Activity of Sera from Certain South American Rodents

  1963cited by this paper
• Guinea pig serum L-asparaginase. Properties, purification, and application to determination of asparagine in biological samples.

  1963cited by this paper
• EVIDENCE THAT THE L-ASPARAGINASE OF GUINEA PIG SERUM IS RESPONSIBLE FOR ITS ANTILYMPHOMA EFFECTS

  1963cited by this paper
• Asparagine biosynthesis in Lactobacillus arabinosus and its control by asparagine through enzyme inhibition and repression.

  1962cited by this paper
• The requirement for L-asparagine of mouse leukemia cells L5178Y in culture.

  1961cited by this paper
• ASPARAGINASE FROM MYCOBACTERIA

  1960cited by this paper
• The amino acid requirements of the Jensen sarcoma in vitro.

  1959cited by this paper
• In vivo and in vitro studies of the action of guinea pig serum against the ascites form of the MurphySturm lymphosarcoma.

  1958cited by this paper
• The asparagine deamidase of Bacillus coagulans and Bacillus stearothermophilus.

  1957cited by this paper
• Evidence that glutamine is a precursor of asparagine in a human cell in tissue culture.

  1957cited by this paper
• Dual requirement of Walker carcinosarcoma 256 in vitro for asparagine and glutamine.

  1956cited by this paper
• Hydrolysis and transfer reactions catalyzed by omega-amidase preparations.

  1955cited by this paper
• Aspartate metabolism and asparagine synthesis in plant systems.

  1955cited by this paper
• Comparative inhibitory effects of glutamic and cysteic acids on aspartic acid utilization.

  1955cited by this paper
• Enzymatic formation of L-asparagine by transamination.

  1954cited by this paper
• Stereospecific asparaginases in smooth Brucella abortus, strain 19.

  1954cited by this paper
• REGRESSION OF TRANSPLANTED LYMPHOMAS INDUCED IN VIVO BY MEANS OF NORMAL GUINEA PIG SERUM

  1953cited by this paper
• The relationship between strepogenin and asparagine.

  1953cited by this paper
• REGRESSION OF TRANSPLANTED LYMPHOMAS INDUCED IN VIVO BY MEANS OF NORMAL GUINEA PIG SERUM

  1953cited by this paper
• The microbiological assay of 'streptogenin' with Lactobacillus casei.

  1952cited by this paper

• Effects of L-asparaginase on rat embryonic development and yolk sac membrane in vitro.

  1989cites this paper
• L-Asparaginase: Basic Aspects

  1975cites this paper
• Effect of L-asparaginase therapy upon serum pseudocholinesterase and ceruloplasmin levels in patients with acute leukemia.

  1972cites this paper
• [Asparaginase, 1969].

  1969cites this paper