Targeting Metabolism for Cancer Therapy.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Cell Chemical Biology

• Publication date

  2017-09-21

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.chembiol.2017.08.028PMID 28938091PMCID PMC5744685
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition

  2017cited by this paper
• Arginine Deprivation Inhibits the Warburg Effect and Upregulates Glutamine Anaplerosis and Serine Biosynthesis in ASS1-Deficient Cancers

  2017cited by this paper
• Abstract P6-11-09: Heavily pre-treated breast cancer patients show promising responses in the first in human study of the first-In-class fatty acid synthase (FASN) inhibitor, TVB-2640 in combination with paclitaxel

  2017cited by this paper
• Oncometabolite D-2-Hydroxyglutarate enhances gene silencing through inhibition of specific H3K36 histone demethylases

  2017cited by this paper
• Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase.

  2017cited by this paper
• Cancer progression by reprogrammed BCAA metabolism in myeloid leukemia

  2017cited by this paper
• Rational Design of Selective Allosteric Inhibitors of PHGDH and Serine Synthesis with Anti-tumor Activity.

  2017cited by this paper
• Modulating the therapeutic response of tumours to dietary serine and glycine starvation

  2017influential reference
• CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells

  2017cited by this paper
• AG311, a small molecule inhibitor of complex I and hypoxia-induced HIF-1α stabilization.

  2017cited by this paper
• Understanding the Intersections between Metabolism and Cancer Biology.

  2017cited by this paper
• Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer

  2017cited by this paper
• PHGDH Defines a Metabolic Subtype in Lung Adenocarcinomas with Poor Prognosis.

  2017influential reference
• Adaptive Reprogramming of De Novo Pyrimidine Synthesis Is a Metabolic Vulnerability in Triple-Negative Breast Cancer.

  2017cited by this paper
• Metabolic Instruction of Immunity.

  2017cited by this paper
• PTEN Regulates Glutamine Flux to Pyrimidine Synthesis and Sensitivity to Dihydroorotate Dehydrogenase Inhibition.

  2017cited by this paper
• Cancer metabolism: a therapeutic perspective

  2017cited by this paper
• Environmental cystine drives glutamine anaplerosis and sensitizes cells to glutaminase inhibition

  2017cited by this paper
• AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations.

  2017influential reference
• Thymidine Catabolism as a Metabolic Strategy for Cancer Survival.

  2017cited by this paper
• New insights into redox homeostasis as a therapeutic target in B-cell malignancies

  2017cited by this paper
• IDH mutations in cancer and progress toward development of targeted therapeutics.

  2016influential reference
• Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells.

  2016influential reference
• A metabolic synthetic lethal strategy with arginine deprivation and chloroquine leads to cell death in ASS1-deficient sarcomas

  2016cited by this paper
• Inhibition of the Polyamine Synthesis Pathway Is Synthetically Lethal with Loss of Argininosuccinate Synthase 1

  2016cited by this paper
• Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin.

  2016influential reference
• A Phase II Clinical Trial of CPI-613 in Patients with Relapsed or Refractory Small Cell Lung Carcinoma

  2016cited by this paper
• Glutathione biosynthesis is a metabolic vulnerability in PI3K/Akt-driven breast cancer

  2016cited by this paper
• Tissue-specific and convergent metabolic transformation of cancer correlates with metastatic potential and patient survival

  2016cited by this paper
• Fundamentals of cancer metabolism

  2016cited by this paper
• L-asparaginase in the treatment of patients with acute lymphoblastic leukemia

  2016cited by this paper
• PKM2, cancer metabolism, and the road ahead

  2016cited by this paper
• A PHGDH inhibitor reveals coordination of serine synthesis and 1-carbon unit fate

  2016influential reference
• From Krebs to clinic: glutamine metabolism to cancer therapy

  2016cited by this paper
• The Emerging Hallmarks of Cancer Metabolism.

  2016cited by this paper
• MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis.

  2016influential reference
• Phosphoinositide 3-kinase inhibitors induce DNA damage through nucleoside depletion

  2016cited by this paper
• Myc-Driven Glycolysis Is a Therapeutic Target in Glioblastoma

  2016cited by this paper
• SF2312 is a natural phosphonate inhibitor of Enolase

  2016cited by this paper
• NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.

  2016cited by this paper
• Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers

  2016cited by this paper
• From Krebs to clinic: glutamine metabolism to cancer therapy

  2016influential reference
• High acetone-butanol-ethanol production in pH-stat co-feeding of acetate and glucose.

  2016cited by this paper
• Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer.

  2016influential reference
• Metabolic Heterogeneity in Human Lung Tumors.

  2016influential reference
• Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio

  2016influential reference
• Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5

  2016influential reference
• PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis.

  2016cited by this paper
• MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells

  2016cited by this paper
• Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.

  2016cited by this paper
• Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway.

  2016cited by this paper
• Altered metabolite levels in cancer: implications for tumour biology and cancer therapy

  2016cited by this paper
• Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion

  2016cited by this paper
• Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small cell lung cancer in preclinical models

  2016influential reference
• Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers

  2016influential reference
• The multifaceted roles of fatty acid synthesis in cancer

  2016cited by this paper
• Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?

  2016cited by this paper
• mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle

  2016cited by this paper
• FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and Gene Expression

  2016cited by this paper
• Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation.

  2015influential reference
• Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression.

  2015cited by this paper
• Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress

  2015cited by this paper
• CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancer

  2015cited by this paper
• Diversion of aspartate in ASS1-deficient tumors fosters de novo pyrimidine synthesis

  2015cited by this paper
• Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H+ symporters

  2015cited by this paper
• An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation

  2015cited by this paper
• Inactivation of SDH and FH cause loss of 5hmC and increased H3K9me3 in paraganglioma/pheochromocytoma and smooth muscle tumors

  2015cited by this paper
• Collateral Lethality: A new therapeutic strategy in oncology.

  2015cited by this paper
• Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA.

  2015cited by this paper
• Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth

  2015cited by this paper
• Oxidative stress inhibits distant metastasis by human melanoma cells

  2015cited by this paper
• Characteristics, clinical outcome, and prognostic significance of IDH mutations in AML

  2015cited by this paper
• Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis.

  2015influential reference
• Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, Leads to Altered Carbohydrate Metabolism in Cancer Cells*

  2015cited by this paper
• NRF2 regulates serine biosynthesis in non-small cell lung cancer

  2015cited by this paper
• Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism

  2015cited by this paper
• Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198.

  2015cited by this paper
• Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH

  2015cited by this paper
• MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells.

  2015cited by this paper
• New IDH1 mutant inhibitors for treatment of acute myeloid leukemia.

  2015cited by this paper
• Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.

  2015cited by this paper
• Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis

  2015cited by this paper
• Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells.

  2015influential reference
• Glutamine Synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma

  2015influential reference
• An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis.

  2015influential reference
• Pyruvate kinase: Function, regulation and role in cancer.

  2015cited by this paper
• Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion.

  2015influential reference
• 2-Deoxy-D-glucose targeting of glucose metabolism in cancer cells as a potential therapy.

  2014cited by this paper
• Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis

  2014cited by this paper
• Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis

  2014influential reference
• Metformin and Cancer Risk and Mortality: A Systematic Review and Meta-analysis Taking into Account Biases and Confounders

  2014cited by this paper
• Role of mesenchymal stem cells in osteosarcoma and metabolic reprogramming of tumor cells

  2014cited by this paper
• Review of clinical practice utility of positron emission tomography with 18F-fluorodeoxyglucose in assessing tumour response to therapy

  2014cited by this paper
• Targeting T Cell Immunometabolism for Cancer Immunotherapy; Understanding the Impact of the Tumor Microenvironment

  2014cited by this paper
• Benefit from procarbazine, lomustine, and vincristine in oligodendroglial tumors is associated with mutation of IDH.

  2014cited by this paper
• Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

  2014cited by this paper
• Antitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer

  2014cited by this paper
• Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells.

  2014cited by this paper
• Quantitative flux analysis reveals folate-dependent NADPH production

  2014cited by this paper
• Acetate dependence of tumors.

  2014cited by this paper

• Proline metabolism supports the hepatocellular carcinoma cell survival by mitigating ROS generation under nutrient starvation.

  2026cites this paper
• Mebendazole impairs the expression and function of enzymes in nucleotide metabolism pathways, leading to Selective Cytotoxicity, Cell Cycle Arrest, and Damage to Cell Morphology in Gastric Cancer.

  2026cites this paper
• Decoding the metabolic-immune axis for novel therapeutics in bladder cancer.

  2026cites this paper
• Vitamin B3 derivatives support pancreatic cancer cell survival and chemotherapy resistance.

  2026cites this paper
• Absolute quantification of brain deuterium metabolic imaging in healthy volunteers and glioblastoma patients at 7T

  2025cites this paper
• α-Ketoglutarate promotes amino acid depletion and suppresses B-cell lymphoma growth and development.

  2025cites this paper
• Immune cell metabolism in cancer drug resistance: Advances in target discovery and clinical translation.

  2025cites this paper
• Arginine Metabolism in Cancer Biology and Immunotherapy

  2025cites this paper
• Metabolic Pathways Involved in Retinal Angiogenesis: Molecular Mechanisms and Therapeutic Targets.

  2025cites this paper
• Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism

  2025cites this paper
• The simultaneous targeted Inhibition of ISG15 and HMGCR disrupts cancer stemness through metabolic collapse and induces synthetic lethality in pancreatic ductal adenocarcinoma

  2025cites this paper
• Advancing Non-Small-Cell Lung Cancer Management Through Multi-Omics Integration: Insights from Genomics, Metabolomics, and Radiomics

  2025cites this paper
• Cancer therapy and cachexia

  2025cites this paper
• Prognostic Significance of the Comprehensive Biomarker Analysis in Colorectal Cancer

  2025cites this paper
• Effect of chemotherapy and different chemotherapeutic regimens on electrocardiographic parameters in breast cancer women: a retrospective and within-subject longitudinal study

  2025cites this paper
• Revealing the landscape of targeting mitochondrial functions and behaviors to overcome cancer chemoresistance

  2025cites this paper
• A micro-metabolic rewiring assay for assessing hypoxia-associated cancer metabolic heterogeneity

  2025cites this paper
• TWIK Complex Expression in Prostate Cancer: Insights into the Biological and Therapeutic Significances of Potassium Ion Channels in Clinical Cancer

  2025cites this paper
• Balancing the cellular budget: Lessons in metabolism from microbes to cancer

  2025cites this paper
• Recent Advances in the Development of Metal-Glycoconjugates for Medicinal Applications

  2025cites this paper
• COMPARATIVE STUDY OF SODIUM OXAMATE AND METFORMIN CYTOTOXICITY AGAINST LEWIS LUNG CARCINOMA CELLS UNDER ANCHORAGE-INDEPENDENT GROWTH.

  2025cites this paper
• A non-enzymatic role of Nudix hydrolase 5 in repressing purine de novo synthesis.

  2025cites this paper
• Drug Repurposing: A Conduit to Unravelling Metabolic Reprogramming for Cancer Treatment.

  2025cites this paper
• Stable Isotope Tracing Experiments Using LC-MS.

  2025cites this paper
• Discovery of a small-molecule inhibitor targeting human GMP synthetase.

  2025cites this paper
• Targeting lactate metabolism to restore immune homeostasis: a precision therapeutic paradigm for rheumatoid arthritis

  2025cites this paper
• CDK12 regulates cellular metabolism to promote glioblastoma growth

  2025cites this paper
• A primer on metabolic contributions in tumor angiogenic microenvironment.

  2025cites this paper
• Carbohydrate-Responsive Element-Binding Protein-Associated Metabolic Changes in Chemically Induced Hepatocarcinogenesis Mouse Model

  2025cites this paper
• Landscape of metabolic alterations and treatment strategies in breast cancer

  2025cites this paper
• Single-cell sequencing and spatial transcriptomics reveal the evolution of glucose metabolism in hepatocellular carcinoma and identify G6PD as a potential therapeutic target

  2025cites this paper
• Mechanism of Marsdenia Tenacissima in Treating Breast Cancer by Targeting the MAPK Signaling Pathway: Utilising Metabolomics, Network Pharmacology, and In Vivo Experiments for Verification.

  2025cites this paper
• Inhibition of lanosterol synthase linking with MAPK/JNK signaling pathway suppresses endometrial cancer

  2025cites this paper
• Immunogenic shift of arginine metabolism triggers systemic metabolic and immunological reprogramming to suppress HER2 + breast cancer

  2025cites this paper
• Mitochondrial, metabolic and bioenergetic adaptations drive plasticity of colorectal cancer cells and shape their chemosensitivity

  2025cites this paper
• Functional mitochondrial respiration is essential for glioblastoma tumour growth

  2025cites this paper
• The Warburg Effect in a Metazoan Capable of Anaerobic Mitochondrial Metabolism.

  2025cites this paper
• Amino acid deprivation vs. mainstream cancer therapeutics: exploring the potential and limitations.

  2025cites this paper
• The role of deiodinases on metabolic alteration in cancer.

  2025cites this paper
• RNA target-independent non-canonical activation (RINCA) of Cas13 trans-nuclease activity.

  2025cites this paper
• Metabolic adaptations in cancer progression.

  2025cites this paper
• Pan‐cancer analysis and oncogenic implications of MGAM and MGAM2: Toward precision oncology and drug repurposing in colorectal cancer

  2025cites this paper
• PDE7A inhibition suppresses triple-negative breast cancer by attenuating de novo pyrimidine biosynthesis

  2025cites this paper
• SGLT-2 inhibitors beyond diabetes: A new frontier in cancer treatment.

  2025cites this paper
• Canagliflozin synergises with serine restriction mediating anti-leukaemic effects in T-cell acute lymphoblastic leukaemia

  2025cites this paper
• Merging metabolic modeling and imaging for screening therapeutic targets in colorectal cancer

  2025cites this paper
• Ditrioxzin synergizes with 2-deoxy-d-glucose to induce redox-dependent metabolic crisis in gastric cancer through dual targeting of peroxiredoxin 3 and glycolysis.

  2025cites this paper
• A machine learning computational framework develops a glutamine metabolism immunity index for improving clinical outcomes in lung adenocarcinoma

  2025cites this paper
• Mechanistic insights into hypoxia‐induced metabolic reprogramming in colorectal cancer through genome‐scale modeling

  2025cites this paper
• A Review of Metabolic Reprogramming in Cancer

  2025cites this paper
• Energetics of Whole Genome Doubling and Genomic Instability.

  2025cites this paper
• Metabolomic, lipidomic and transcriptomic profiles provide insights into meat quality differences among four pork cuts

  2025cites this paper
• TP53-dependent antitumor effects of DHODH Inhibition in nasopharyngeal carcinoma

  2025cites this paper
• Engineering Inorganic Nanoparticles to Induce Cuproptosis: A New Strategy for Cancer Therapy

  2025cites this paper
• A high throughput assay for phosphoribosylformylglycinamidine synthase

  2025cites this paper
• Exploring metabolic pathways in gastrointestinal cancer: new evidence of causality

  2025cites this paper
• Wide-Field Optical Redox Imaging with Leading-Edge Detection Enables Assessment of Treatment Response and Heterogeneity in Patient-Derived Cancer Organoids

  2025cites this paper
• PAX3-FOXO1 Drives Targetable Cell State-Dependent Metabolic Vulnerabilities in Rhabdomyosarcoma.

  2025cites this paper
• Compact and cGMP-compliant automated synthesis of [18F]FSPG on the Trasis AllinOne™

  2025cites this paper
• MRPL21-PARP1 axis promotes cisplatin resistance in head and neck squamous cell carcinoma by inhibiting autophagy through the PI3K/AKT/mTOR signaling pathway

  2025cites this paper
• Investigating lung cancer microenvironment from cell segmentation of pathological image and its application in prognostic stratification

  2025cites this paper
• Effects of colloids with different compositions on benzophenone-3 biotoxicity in zebrafish embryos.

  2025cites this paper
• Metabolomic and gene networks approaches reveal the role of mitochondrial membrane proteins in response of human melanoma cells to THz radiation.

  2025cites this paper
• Perilipin2-dependent lipid droplets accumulation promotes metastasis of oral squamous cell carcinoma via epithelial-mesenchymal transition

  2025cites this paper
• Metabolic heterogeneity in tumor cells impacts immunology in lung squamous cell carcinoma

  2025cites this paper
• Metabolic landscape and rewiring in normal hematopoiesis, leukemia and aging.

  2025cites this paper
• Metal–organic layer delivers 3-bromopyruvate to mitochondria for metabolic regulation and cancer radio-immunotherapy

  2025cites this paper
• Reprogramming Glutamine Metabolism of Dendritic Cells Boosts Lymph Nodes Migration and Tumor Immunotherapy

  2025cites this paper
• Functional profiling reveals a non-enzymatic role of NUDT5 in repressing purine de novo synthesis

  2025cites this paper
• Targeting PI3K inhibitor resistance in breast cancer with metabolic drugs

  2025cites this paper
• Cell-Free DNA (cfDNA) Regulates Metabolic Remodeling, Sustaining Proliferation, Quiescence, and Migration in MDA-MB-231, a Triple-Negative Breast Carcinoma (TNBC) Cell Line

  2025cites this paper
• Cell-Free DNA (cfDNA) Regulates Metabolic Remodeling in the ES-2 Ovarian Carcinoma Cell Line, Influencing Cell Proliferation, Quiescence, and Chemoresistance in a Cell-of-Origin-Specific Manner

  2025cites this paper
• Nampt as a new therapeutic target for modulating NAD+ levels in metabolic, cardiovascular and neurodegenerative diseases.

  2025cites this paper
• Research progress on cuproptosis and copper related anti-tumor therapy

  2025cites this paper
• Metabolic Pathway Analysis of Tumors Using Stable Isotopes.

  2025cites this paper
• Hepatotoxicity of Chemotherapy and Immune Checkpoint Inhibitors.

  2025cites this paper
• NSD1 mutation status determines metabolic inhibitor sensitivity in head and neck squamous cell carcinomas by regulating mitochondrial respiration

  2025cites this paper
• Targeting LAT1 with JPH203 to reduce TNBC proliferation and reshape suppressive immune microenvironment by blocking essential amino acid uptake

  2025cites this paper
• Identification of metabolism-associated molecular classification for effect and prognosis in lung adenocarcinoma based on multidatabases including the cancer genome atlas and gene expression omnibus

  2025cites this paper
• USP39 regulates pyruvate handling in non-small cell lung cancer

  2024cites this paper
• Local glycolysis-modulating hydrogel microspheres for a combined anti-tumor and anti-metastasis strategy through metabolic trapping strategy.

  2024cites this paper
• GLUT-1 Overexpression in Neoplastic Cells

  2024cites this paper
• The T cell-mediated tumor killing patterns revealed tumor heterogeneous and proposed treatment recommendation in ovary cancer

  2024cites this paper
• Metabolic Adaptations in Cancer and the Host Using Drosophila Models and Advanced Tools

  2024cites this paper
• A Novel Peroxisome-Related Gene Signature Predicts Breast Cancer Prognosis and Correlates with T Cell Suppression

  2024cites this paper
• Structure activity relationship for anticancer activities of spirooxindole derivatives: A comprehensive review.

  2024cites this paper
• Toward personalized cancer management: Role of precision nutrition–diet interventions

  2024cites this paper
• One stone, three birds: Construction of Cu/ZIF-8@DSF@GOx/HA nanoplatform for synergistic starvation therapy enhanced chemo-/chemodynamic therapy.

  2024cites this paper
• Changes in tumor and cardiac metabolism upon immune checkpoint

  2024cites this paper
• Immunogenic shift of arginine metabolism triggers systemic metabolic and immunological reprogramming to prevent HER2+ breast cancer

  2024cites this paper
• Site of breast cancer metastasis is independent of single nutrient levels

  2024cites this paper
• Progress in research of ferroptosis in gastrointestinal tumors

  2024cites this paper
• Molecular and modular intricacies of precision oncology

  2024cites this paper
• Advancing Anticancer Drug Discovery: Leveraging Metabolomics and Machine Learning for Mode of Action Prediction by Pattern Recognition

  2024cites this paper
• Metabolic Reprogramming in Cancer: Implications for Immunosuppressive Microenvironment

  2024cites this paper
• DGKH-mediated phosphatidic acid oncometabolism as a driver of self-renewal and therapy resistance in HCC.

  2024cites this paper
• Withaferin A decreases glycolytic reprogramming in breast cancer

  2024cites this paper
• Development of a Competitive Nutrient-Based T-Cell Immunotherapy Designed to Block the Adaptive Warburg Effect in Acute Myeloid Leukemia

  2024cites this paper
• Cell calcification reverses the chemoresistance of cancer cells via the conversion of glycolipid metabolism.

  2024cites this paper
• Technologies for Decoding Cancer Metabolism with Spatial Resolution.

  2024cites this paper