Neuregulin 1 up‐regulates the expression of nicotinic acetylcholine receptors through the ErbB2/ErbB3‐PI3K‐MAPK signaling cascade in adult autonomic ganglion neurons

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Journal of Neurochemistry

• Publication date

  2013-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/jnc.12109PMID 23199222
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Mammalian nicotinic acetylcholine receptors: from structure to function.

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  2006cited by this paper
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  2006cited by this paper
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  2006cited by this paper
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  2006cited by this paper
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  2005cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2003cited by this paper
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  2002cited by this paper
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  2002cited by this paper
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  2001cited by this paper
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  1999cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998influential reference
• Heterogeneity of Nicotinic Receptor Class and Subunit mRNA Expression among Individual Parasympathetic Neurons from Rat Intracardiac Ganglia

  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1997influential reference
• Expression of a chicken ciliary neurotrophic factor in targets of ciliary ganglion neurons during and after the cell‐death phase

  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
• ARIA can be released from extracellular matrix through cleavage of a heparin-binding domain

  1995cited by this paper
• Phenotype‐specific expression of T‐type calcium channels in neurons of the major pelvic ganglion of the adult male rat.

  1995influential reference
• Rapid Communication: Nerve Growth Factor Increases the Transcriptional Activity of the Rat Neuronal Nicotinic Acetylcholine Receptor β4 Subunit Promoter in Transfected PC12 Cells

  1994cited by this paper
• A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

  1994cited by this paper
• Comparison of neuronal nicotinic receptors in rat sympathetic neurones with subunit pairs expressed in Xenopus oocytes.

  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
• Nervous control of the urogenital system

  1993cited by this paper
• ARIA, a protein that stimulates acetylcholine receptor synthesis, also induces tyrosine phosphorylation of a 185-kDa muscle transmembrane protein.

  1993cited by this paper
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  1993cited by this paper
• The expression of nicotinic acetylcholine receptors by PC12 cells treated with NGF

  1992cited by this paper
• Acetylcholine receptor-inducing activity stimulates expression of the epsilon-subunit gene of the muscle acetylcholine receptor.

  1991cited by this paper
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  1975cited by this paper

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