Recent Advances in Bronchopulmonary Dysplasia: Pathophysiology, Prevention, and Treatment

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Lung

• Publication date

  2018-01-27

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s00408-018-0084-zPMID 29374791PMCID PMC5856637
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pulmonary hypertension associated with bronchopulmonary dysplasia in preterm infants.

  2017cited by this paper
• Intratracheal Administration of Budesonide‐Surfactant in Prevention of Bronchopulmonary Dysplasia in Very Low Birth Weight Infants: A Systematic Review and Meta‐Analysis

  2017cited by this paper
• Bronchopulmonary Dysplasia: Chronic Lung Disease of Infancy and Long-Term Pulmonary Outcomes

  2017cited by this paper
• Revisiting the Definition of Bronchopulmonary Dysplasia: Effect of Changing Panoply of Respiratory Support for Preterm Neonates

  2017influential reference
• Caffeine to improve breathing effort of preterm infants at birth: a randomized controlled trial

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• Decrease in delivery room intubation rates after use of nasal intermittent positive pressure ventilation in the delivery room for resuscitation of very low birth weight infants.

  2017cited by this paper
• Association Between Early Low-Dose Hydrocortisone Therapy in Extremely Preterm Neonates and Neurodevelopmental Outcomes at 2 Years of Age

  2017cited by this paper
• Anti-inflammatory Agents for the Prevention of Bronchopulmonary Dysplasia

  2016cited by this paper
• Mandatory Closure Versus Nonintervention for Patent Ductus Arteriosus in Very Preterm Infants.

  2016cited by this paper
• Vitamin A supplementation to prevent mortality and short- and long-term morbidity in very low birth weight infants.

  2016cited by this paper
• Effect of early low-dose hydrocortisone on survival without bronchopulmonary dysplasia in extremely preterm infants (PREMILOC): a double-blind, placebo-controlled, multicentre, randomised trial.

  2016cited by this paper
• The Airway Microbiome at Birth

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• Sildenafil therapy in bronchopulmonary dysplasia-associated pulmonary hypertension: a retrospective study of efficacy and safety

  2015cited by this paper
• Mesenchymal stem cells for the prevention and treatment of bronchopulmonary dysplasia in preterm infants.

  2015cited by this paper
• Right ventricular function in preterm and term neonates: reference values for right ventricle areas and fractional area of change.

  2015cited by this paper
• Off-Label Use of Inhaled Nitric Oxide After Release of NIH Consensus Statement

  2015cited by this paper
• Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society

  2015cited by this paper
• Integrated genomic analyses in bronchopulmonary dysplasia.

  2015cited by this paper
• Perinatal conditions related to growth restriction and inflammation are associated with an increased risk of bronchopulmonary dysplasia

  2015cited by this paper
• The airway microbiome of intubated premature infants: characteristics and changes that predict the development of bronchopulmonary dysplasia

  2014cited by this paper
• Mesenchymal stem cells for bronchopulmonary dysplasia: phase 1 dose-escalation clinical trial.

  2014cited by this paper
• Early (< 8 days) postnatal corticosteroids for preventing chronic lung disease in preterm infants.

  2014cited by this paper
• The Lung Alveolar Lipofibroblast: An Evolutionary Strategy Against Neonatal Hyperoxic Lung Injury

  2014cited by this paper
• Trends in caffeine use and association between clinical outcomes and timing of therapy in very low birth weight infants.

  2014cited by this paper
• Vitamin D supplementation blocks pulmonary structural and functional changes in a rat model of perinatal vitamin D deficiency.

  2014cited by this paper
• Association Between Pulmonary Ureaplasma Colonization and Bronchopulmonary Dysplasia in Preterm Infants: Updated Systematic Review and Meta-analysis

  2014cited by this paper
• Effectiveness of vitamin A in the prevention of complications of prematurity.

  2014cited by this paper
• Effects of early inhaled nitric oxide therapy and vitamin A supplementation on the risk for bronchopulmonary dysplasia in premature newborns with respiratory failure.

  2014cited by this paper
• Vitamin D treatment improves survival and infant lung structure after intra-amniotic endotoxin exposure in rats: potential role for the prevention of bronchopulmonary dysplasia.

  2014cited by this paper
• Late (> 7 days) postnatal corticosteroids for chronic lung disease in preterm infants.

  2014cited by this paper
• Neonatal Gram Negative and Candida Sepsis Survival and Neurodevelopmental Outcome at the Corrected Age of 24 Months

  2013cited by this paper
• Bronchopulmonary dysplasia and neurodevelopmental outcome in extremely preterm neonates

  2013cited by this paper
• Avoiding Endotracheal Ventilation to Prevent Bronchopulmonary Dysplasia: A Meta-analysis

  2013cited by this paper
• Optimal Oxygenation of Extremely Low Birth Weight Infants: A Meta-Analysis and Systematic Review of the Oxygen Saturation Target Studies

  2013cited by this paper
• Impact of patient selection on outcomes of PDA in very low birth weight infants.

  2013cited by this paper
• Stem cell-based therapy for neonatal lung disease—it’s in the juice

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• Interleukin-1 receptor antagonist prevents murine bronchopulmonary dysplasia induced by perinatal inflammation and hyperoxia

  2013cited by this paper
• Using Cell-Based Strategies to Break the Link between Bronchopulmonary Dysplasia and the Development of Chronic Lung Disease in Later Life

  2013cited by this paper
• Exogenous surfactant therapy in 2013: what is next? who, when and how should we treat newborn infants in the future?

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• Genetic associations of surfactant protein D and angiotensin-converting enzyme with lung disease in preterm neonates

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• PPARγ Signaling Mediates the Evolution, Development, Homeostasis, and Repair of the Lung

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• SP-B and SP-C Containing New Synthetic Surfactant for Treatment of Extremely Immature Lamb Lung

  2012cited by this paper
• Prophylactic versus Selective Use of Surfactant in Preventing Morbidity and Mortality in Preterm Infants

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• Prophylactic versus selective use of surfactant in preventing morbidity and mortality in preterm infants.

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• Correlation between serum caffeine levels and changes in cytokine profile in a cohort of preterm infants.

  2011cited by this paper
• NIH Consensus Development Conference Statement: Inhaled Nitric-Oxide Therapy for Premature Infants

  2011cited by this paper
• Lung Function and Respiratory Symptoms at 11 Years in Children Born Extremely Preterm: The Epicure Study

  2011cited by this paper
• Identification of SPOCK2 as a susceptibility gene for bronchopulmonary dysplasia.

  2011cited by this paper
• Vitamin A supplementation to prevent mortality and short- and long-term morbidity in very low birthweight infants.

  2011cited by this paper
• Intravenous or enteral loop diuretics for preterm infants with (or developing) chronic lung disease.

  2011cited by this paper
• Concise Review: Mesenchymal Stem Cells for Acute Lung Injury: Role of Paracrine Soluble Factors

  2011cited by this paper
• Intravenous or enteral loop diuretics for preterm infants with (or developing) chronic lung disease.

  2011cited by this paper
• Use of azithromycin for the prevention of bronchopulmonary dysplasia in preterm infants: a randomized, double‐blind, placebo controlled trial

  2011cited by this paper
• Volume-Targeted versus Pressure-Limited Ventilation for Preterm Infants: A Systematic Review and Meta-Analysis

  2011cited by this paper
• Early surgical ligation versus a conservative approach for management of patent ductus arteriosus that fails to close after indomethacin treatment.

  2010cited by this paper
• Serial Measurements of Lung Function in a Cohort of Young Children With Bronchopulmonary Dysplasia

  2010cited by this paper
• Target ranges of oxygen saturation in extremely preterm infants.

  2010cited by this paper
• NIH consensus development conference: Inhaled nitric oxide therapy for premature infants.

  2010cited by this paper
• Target Ranges of Oxygen Saturation in Extremely Preterm Infants

  2010cited by this paper
• Chorioamnionitis alters the response to surfactant in preterm infants.

  2010cited by this paper
• Lung function and respiratory symptoms at 11 years in children born extremely preterm: the EPICure study.

  2010cited by this paper
• Epidemiological Characteristics and Resource Use in Neonates With Bronchopulmonary Dysplasia: 1993–2006

  2010cited by this paper
• Sildenafil attenuates pulmonary inflammation and fibrin deposition, mortality and right ventricular hypertrophy in neonatal hyperoxic lung injury

  2009cited by this paper
• Reduction in the Incidence of Chronic Lung Disease in Very Low Birth Weight Infants: Results of a Quality Improvement Process in a Tertiary Level Neonatal Intensive Care Unit

  2009cited by this paper
• A Pilot Randomized, Controlled Trial of Later Treatment With a Peptide-Containing, Synthetic Surfactant for the Prevention of Bronchopulmonary Dysplasia

  2009cited by this paper
• Late (>7 days) postnatal corticosteroids for chronic lung disease in preterm infants.

  2009cited by this paper
• 1alpha,25(OH)2D3 and its 3-epimer promote rat lung alveolar epithelial-mesenchymal interactions and inhibit lipofibroblast apoptosis.

  2009cited by this paper
• Synchronized Nasal Intermittent Positive-Pressure Ventilation and Neonatal Outcomes

  2009cited by this paper
• Early (< 8 days) postnatal corticosteroids for preventing chronic lung disease in preterm infants.

  2009cited by this paper
• Obstetric interventions for babies born before 28 weeks of gestation in Europe: results of the MOSAIC study

  2009cited by this paper
• The role of patent ductus arteriosus ligation in bronchopulmonary dysplasia: reexamining a randomized controlled trial.

  2009cited by this paper
• Fetal Growth Restriction and Chronic Lung Disease Among Infants Born Before the 28th Week of Gestation

  2009cited by this paper
• Very Early Surfactant Without Mandatory Ventilation in Premature Infants Treated With Early Continuous Positive Airway Pressure: A Randomized, Controlled Trial

  2009cited by this paper
• Finding the Optimal Postnatal Dexamethasone Regimen for Preterm Infants at Risk of Bronchopulmonary Dysplasia: A Systematic Review of Placebo-Controlled Trials

  2009cited by this paper
• Effects of transfusions in extremely low birth weight infants: a retrospective study.

  2009cited by this paper
• Prevention and Treatment of Bronchopulmonary Dysplasia: Contemporary Status and Future Outlook

  2008cited by this paper
• Early Intratracheal Instillation of Budesonide Using Surfactant as a Vehicle to Prevent Chronic Lung Disease in Preterm Infants: A Pilot Study

  2008cited by this paper
• Recombinant Human Clara Cell Secretory Protein Treatment Increases Lung mRNA Expression of Surfactant Proteins and Vascular Endothelial Growth Factor in a Premature Lamb Model of Respiratory Distress Syndrome

  2008cited by this paper
• One-year respiratory outcomes of preterm infants enrolled in the Nitric Oxide (to prevent) Chronic Lung Disease trial.

  2008cited by this paper
• Heritability of Bronchopulmonary Dysplasia, Defined According to the Consensus Statement of the National Institutes of Health

  2008cited by this paper
• Azithromycin in the extremely low birth weight infant for the prevention of Bronchopulmonary Dysplasia: a pilot study

  2007cited by this paper
• Chronic lung disease after premature birth.

  2007cited by this paper
• Vitamin A supplementation to prevent mortality and short and long-term morbidity in very low birthweight infants.

  2007cited by this paper
• Postnatal Dexamethasone Therapy and Cerebral Tissue Volumes in Extremely Low Birth Weight Infants

  2007cited by this paper
• Early surfactant administration with brief ventilation vs selective surfactant and continued mechanical ventilation for preterm infants with or at risk for respiratory distress syndrome.

  2007cited by this paper
• Early surfactant administration with brief ventilation vs. selective surfactant and continued mechanical ventilation for preterm infants with or at risk for respiratory distress syndrome.

  2007cited by this paper
• Nasal intermittent mandatory ventilation versus nasal continuous positive airway pressure for respiratory distress syndrome: a randomized, controlled, prospective study.

  2007cited by this paper
• Is there a causal relationship between the receipt of blood transfusions and the development of chronic lung disease of prematurity?

  2006cited by this paper
• Familial and Genetic Susceptibility to Major Neonatal Morbidities in Preterm Twins

  2006cited by this paper
• Safety, Pharmacokinetics, and Anti-inflammatory Effects of Intratracheal Recombinant Human Clara Cell Protein in Premature Infants with Respiratory Distress Syndrome

  2005cited by this paper
• Recombinant human Clara cell secretory protein in acute lung injury of the rabbit: Effect of route of administration

  2005cited by this paper
• Inhaled nitric oxide for premature infants with severe respiratory failure.

  2005cited by this paper
• Vitamin A Supplementation for Extremely Low Birth Weight Infants: Outcome at 18 to 22 Months

  2005cited by this paper
• Oxygen-saturation targets and outcomes in extremely preterm infants.

  2003cited by this paper
• Vitamin A supplementation for extremely low-birth-weight infants

  2000cited by this paper
• Intravenous or enteral loop diuretics for preterm infants with (or developing) chronic lung disease.

  2000cited by this paper
• Vitamin A supplementation for extremely-low-birth-weight infants. National Institute of Child Health and Human Development Neonatal Research Network.

  1999cited by this paper
• Very low birth weight infants

  1986cited by this paper
• Pulmonary disease following respirator therapy of hyaline-membrane disease. Bronchopulmonary dysplasia.

  1967cited by this paper

• Evaluation of nurse-led early graded rehabilitation and pulmonary ultrasound-guided comprehensive chest physical therapy in comatose ICU patients

  2026cites this paper
• Respiratory Practices to Prevent or Treat Evolving Bronchopulmonary Dysplasia: A European Survey.

  2026cites this paper
• Low hyper-oxygen exposure induces p21-dependent p53-independent senescence in alveolar cells

  2026cites this paper
• Evaluation of the Predictive Value of Lung Ultrasound Scoring Systems in Assessing Bronchopulmonary Dysplasia Severity Among Preterm Infants: Correlation Analysis with Therapeutic Strategies and Clinical Management Protocols

  2025cites this paper
• Nutrition Strategies for the Preterm Infant with Bronchopulmonary Dysplasia

  2025cites this paper
• Lipidomic signatures of tracheal aspirate diagnostic biomarkers in preterm infants with bronchopulmonary dysplasia

  2025cites this paper
• Effect of bronchopulmonary dysplasia and pneumonia on the neurodevelopment of preterm infants: a cerebral blood flow study

  2025influential citation
• Dynamic Risk‐Stratification Models for Bronchopulmonary Dysplasia in Extremely Preterm Very Low Birth Weight Infants

  2025cites this paper
• Identification and Validation of TFF3 as a Diagnostic Biomarker and Therapeutic Agent for Bronchopulmonary Dysplasia

  2025cites this paper
• Human OPN-derived peptide SV prevents BPD model through interacting with KIF5B to repair mitochondrial damage and inhibit apoptosis

  2025cites this paper
• Clinical Improvements Following Posterior Cranial Vault Remodeling in a Patient with Bronchopulmonary Dysplasia: A Case Report

  2025cites this paper
• Betaine improves hyperoxic lung injury through downregulating pulmonary macrophage pyroptosis in newborn mice.

  2025cites this paper
• Hematological Parameters at Birth Fail to Predict Intraventricular Hemorrhage in Very Preterm Infants.

  2025cites this paper
• Enhanced vs. standard low dose dexamethasone treatment on respiratory outcomes of preterm infants with bronchopulmonary dysplasia

  2025cites this paper
• Observations on IL-2-inducible tyrosine kinase expression and Th17/Treg cell ratio in hyperoxia-induced bronchopulmonary dysplasia in neonatal rats.

  2025cites this paper
• Association of early respiratory support with mortality and bronchopulmonary dysplasia in very-low-birth-weight preterm infants.

  2025cites this paper
• Association of early postnatal decline in fetal hemoglobin with bronchopulmonary dysplasia in very low birth weight infants: a cohort study

  2025cites this paper
• Sex, hormones, and lung health.

  2025cites this paper
• Associated factors and clinical outcomes of feeding intolerance in preterm extremely low birthweight infants

  2025cites this paper
• Aerosol inhalation of dimeric artesunate phospholipid-conjugated liposomes ameliorates inflammation, fibrosis, and ferroptosis in neonatal mice with hyperoxia-induced lung injury

  2025cites this paper
• Association of Early Caffeine Therapy with Risk Reduction of Moderate-to-Severe Bronchopulmonary Dysplasia in Preterm Infants

  2025cites this paper
• Adverse perinatal outcomes associated with respiratory distress syndrome in preterm infants: a retrospective analysis

  2025cites this paper
• Endothelium and Systemic Inflammation in Neonates and Children.

  2025cites this paper
• Severe Neonatal Morbidity and All-Cause and Cause-Specific Mortality Through Infancy and Late Adolescence.

  2025cites this paper
• SIRT1 and its SUMOylation attenuate hyperoxia-induced lung injury by improving mitochondrial biogenesis and fusion.

  2025cites this paper
• Advances in Research on the Association between Uric Acid and Bronchopulmonary Dysplasia

  2025cites this paper
• Ureaplasma in neonatal gastric fluid contributing to bronchopulmonary dysplasia

  2025cites this paper
• Proteomic analysis of premature umbilical cord blood and its relationship with bronchopulmonary dysplasia

  2025cites this paper
• Proline betaine facilitates angiogenesis in bronchopulmonary dysplasia.

  2025cites this paper
• The Central Role of Cytochrome P450 Reductase (CPR) in Hyperoxic Lung Injury

  2025cites this paper
• Bronchopulmonary dysplasia: some pathophysiological aspects

  2025cites this paper
• Human milk and bronchopulmonary dysplasia have a dose-dependent effect: a cohort study

  2025cites this paper
• Celastrol has beneficial effects on pulmonary hypertension associated with bronchopulmonary dysplasia: Preclinical study outcomes.

  2025cites this paper
• Hepatitis B vaccination of preterm infants and risk of bronchopulmonary dysplasia: a cohort study, Australia

  2025cites this paper
• Identification of serum metabolite biomarkers in premature infants with bronchopulmonary dysplasia: protocol for a multicentre prospective observational cohort study

  2025cites this paper
• Efficacy of pulmonary surfactant with budesonide in premature infants: A systematic review and meta-analysis

  2025cites this paper
• Mitochondrial DNA mutations in extremely preterm infants with bronchopulmonary dysplasia.

  2024cites this paper
• Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia

  2024cites this paper
• Exploratory analysis of the key role of immune function changes in BPD

  2024cites this paper
• Analysis of Fibroblast Growth Factor 2 Impact and Mechanism on Broncho-Pulmonary Dysplasia

  2024cites this paper
• LncRNA MIAT binding to GATA3 activates MAPK signaling pathway and influences bronchopulmonary dysplasia.

  2024cites this paper
• Circ‐ECH1 May Compete With miR‐708‐5p to Regulate Ntrk2 in Bronchopulmonary Dysplasia

  2024cites this paper
• Predictive analytics in bronchopulmonary dysplasia: past, present, and future

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• Knockdown of the long noncoding RNA VSIG2-1:1 promotes the angiogenic ability of human pulmonary microvascular endothelial cells by activating the VEGF/PI3K/AKT pathway

  2024cites this paper
• Analysis of variable metabolites in preterm infants with bronchopulmonary dysplasia: a systematic review and meta-analysis

  2024cites this paper
• Analysis of blood metabolite characteristics at birth in preterm infants with bronchopulmonary dysplasia: an observational cohort study

  2024cites this paper
• Predictive modeling of bronchopulmonary dysplasia in premature infants: the impact of new diagnostic standards

  2024cites this paper
• Incidence and factors associated with bronchopulmonary dysplasia in discharges from Neonatal Intensive Care Units in Northern Minas Gerais

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• Incidência e fatores associados à displasia broncopulmonar em egressos de Unidades de Terapia Intensiva Neonatal no norte de Minas Gerais

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• Association between early metabolic acidosis and bronchopulmonary dysplasia/death in preterm infants born at less than 28 weeks’ gestation: an observational cohort study

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• Implication of m6A Methylation Regulators in the Immune Microenvironment of Bronchopulmonary Dysplasia

  2024cites this paper
• Stem cell-derived extracellular vesicles: a potential intervention for Bronchopulmonary Dysplasia

  2024cites this paper
• A Comprehensive Consolidation of Data on the Relationship Between Surfactant Protein-B (SFTPB) Polymorphisms and Susceptibility to Bronchopulmonary Dysplasia

  2024cites this paper
• Fetal origin of bronchopulmonary dysplasia: contribution of intrauterine inflammation

  2024cites this paper
• Systemic steroids and bronchopulmonary dysplasia: a systematic review and meta-analysis

  2024cites this paper
• [Role of reactive oxygen species/silent information regulator 1 in hyperoxia-induced bronchial epithelial cell injury].

  2024cites this paper
• Association between Ureaplasma urealyticum colonization and bronchopulmonary dysplasia in preterm infants: a systematic review and meta-analysis

  2024cites this paper
• Hyperoxia exposure induces ferroptosis and apoptosis by downregulating PLAGL2 and repressing HIF-1α/VEGF signaling pathway in newborn alveolar typeII epithelial cell

  2024cites this paper
• miR-3202 inhibits bronchopulmonary dysplasia-mediated apoptosis and oxidative stress in bronchial epithelial cells via targeting RAG1.

  2024cites this paper
• RETRACTED: Effect of Oridonin on Experimental Animal Model of Bronchopulmonary Dysplasia

  2024cites this paper
• Research progress of microvascular development in bronchopulmonary dysplasia

  2024cites this paper
• High oxygen exposure’s impact on newborn mice: Temporal changes observed via micro-computed tomography

  2024cites this paper
• Deficiency of Secreted Phosphoprotein 1 Alleviates Hyperoxia-induced Bronchopulmonary Dysplasia in Neonatal Mice

  2024cites this paper
• [Risk factors for bronchopulmonary dysplasia in twin preterm infants: a multicenter study].

  2024cites this paper
• Incidence and Predictors of Bronchopulmonary Dysplasia Development and Severity Among Preterm Infants Born at 32 Weeks of Gestation or Less

  2024cites this paper
• Corticosteroids for the prevention and treatment of bronchopulmonary dysplasia: an overview of systematic reviews.

  2024cites this paper
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• The association of serum vitamin D level and neonatal respiratory distress syndrome

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• Molsidomine decreases hyperoxia-induced lung injury in neonatal rats

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  2023cites this paper
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  2023cites this paper
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• Effect of Small Volume Blood Sampling on the Outcomes of Very Low Birth Weight Preterm Infants

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• Research Progress in Bronchopulmonary Dysplasia: A Narrative Review by Etiology

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