Proteomics and islet research.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Advances in Experimental Medicine and Biology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/978-90-481-3271-3_16PMID 20217506
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Detection of differential proteomes associated with the development of type 2 diabetes in the Zucker rat model using the iTRAQ technique.

  2011cited by this paper
• Oleate-induced beta cell dysfunction and apoptosis: a proteomic approach to glucolipotoxicity by an unsaturated fatty acid.

  2011cited by this paper
• Enrichment techniques employed in phosphoproteomics

  2011cited by this paper
• Nanotechniques in proteomics: current status, promises and challenges.

  2010cited by this paper
• Ultrasensitive nanoelectrospray ionization-mass spectrometry using poly(dimethylsiloxane) microchips with monolithically integrated emitters.

  2010cited by this paper
• Microfluidic platforms for single-cell analysis.

  2010cited by this paper
• Interfacing droplet microfluidics with chemical separation for cellular analysis

  2010cited by this paper
• Proteomics in diabetes research.

  2009cited by this paper
• Proteins altered by elevated levels of palmitate or glucose implicated in impaired glucose-stimulated insulin secretion

  2009cited by this paper
• The RhoGDI-alpha/JNK signaling pathway plays a significant role in mycophenolic acid-induced apoptosis in an insulin-secreting cell line.

  2009cited by this paper
• MicroRNAs: Target Recognition and Regulatory Functions

  2009cited by this paper
• Dilution-free analysis from picoliter droplets by nano-electrospray ionization mass spectrometry.

  2009cited by this paper
• Detection of differential proteomes of human beta-cells during islet-like differentiation using iTRAQ labeling.

  2009cited by this paper
• Role of innate immunity in triggering and tuning of autoimmune diabetes.

  2009cited by this paper
• The Identification of Potential Factors Associated with the Development of Type 2 Diabetes

  2008cited by this paper
• Metabolomic and proteomic analysis of a clonal insulin-producing beta-cell line (INS-1 832/13).

  2008cited by this paper
• Glucolipotoxicity of the pancreatic beta-cell: myth or reality?

  2008cited by this paper
• Functional cloning by phage display.

  2008cited by this paper
• Novel microtubule-interacting phenoxy pyridine and phenyl sulfanyl pyridine analogues for cancer therapy.

  2008cited by this paper
• Comparative LC‐MS: A landscape of peaks and valleys

  2008cited by this paper
• Peptide microarrays: next generation biochips for detection, diagnostics and high-throughput screening.

  2008cited by this paper
• Characterization of the mouse pancreatic islet proteome and comparative analysis with other mouse tissues.

  2008cited by this paper
• Significance analysis of microarray for relative quantitation of LC/MS data in proteomics

  2008cited by this paper
• Glucolipotoxicity: fuel excess and beta-cell dysfunction.

  2008cited by this paper
• Proteomic and transcriptomic analysis for streptozotocin‐induced diabetic rat pancreas in response to fungal polysaccharide treatments

  2008cited by this paper
• Epothilones: a novel class of microtubule-stabilizing drugs for the treatment of cancer.

  2008cited by this paper
• Direct profiling and identification of peptide expression differences in the pancreas of control and ob/ob mice by imaging mass spectrometry

  2008cited by this paper
• Molecular and cellular approaches for the detection of protein-protein interactions: latest techniques and current limitations.

  2008cited by this paper
• Elastomeric microchip electrospray emitter for stable cone-jet mode operation in the nanoflow regime.

  2008cited by this paper
• Mass spectrometry: m/z 1983-2008.

  2008cited by this paper
• Glucolipotoxicity : Fuel Excess and-Cell Dysfunction

  2008cited by this paper
• Integrative analysis for finding genes and networks involved in diabetes and other complex diseases

  2007cited by this paper
• Long-Term Exposure to Glucose and Lipids Inhibits Glucose-Induced Insulin Secretion Downstream of Granule Fusion With Plasma Membrane

  2007cited by this paper
• Activation of peroxisome proliferator-activated receptor-γ protects pancreatic β-cells from cytokine-induced cytotoxicity via NFκB pathway

  2007cited by this paper
• Use of SELDI-TOF mass spectrometry for identification of new biomarkers: potential and limitations.

  2007cited by this paper
• Fatty acids and glucose in high concentration down-regulates ATP synthase β-subunit protein expression in INS-1 cells

  2007cited by this paper
• Two-dimensional electrophoresis in proteome expression analysis.

  2007cited by this paper
• Proteomics Analysis of Insulin Secretory Granules*S

  2007cited by this paper
• Proteomic approaches for serum biomarker discovery in cancer.

  2007cited by this paper
• Activation of peroxisome proliferator-activated receptor-gamma protects pancreatic beta-cells from cytokine-induced cytotoxicity via NF kappaB pathway.

  2007cited by this paper
• The age of crosstalk: phosphorylation, ubiquitination, and beyond.

  2007cited by this paper
• Differential protein expression in pancreatic islets after treatment with an imidazoline compound

  2007cited by this paper
• Applications and current challenges of proteomic approaches, focusing on two-dimensional electrophoresis

  2007cited by this paper
• Evaluation of the SELDI‐TOF MS technique for protein profiling of pancreatic islets exposed to glucose and oleate

  2007cited by this paper
• A review of quantitative methods for proteomic studies.

  2007cited by this paper
• Proteomics analysis in lung cancer: Challenges and opportunities

  2007cited by this paper
• Shotgun proteomics using the iTRAQ isobaric tags.

  2006cited by this paper
• Antidiabetic agents from medicinal plants.

  2006cited by this paper
• Mitochondrial protein patterns correlating with impaired insulin secretion from INS‐1E cells exposed to elevated glucose concentrations

  2006cited by this paper
• Proteomic screening of glucose‐responsive and glucose non‐responsive MIN‐6 beta cells reveals differential expression of proteins involved in protein folding, secretion and oxidative stress

  2006cited by this paper
• Antibody Microarrays: Current Status and Key Technological Advances

  2006cited by this paper
• Characterization of the human pancreatic islet proteome by two-dimensional LC/MS/MS.

  2006cited by this paper
• Proteomic analysis by multidimensional protein identification technology.

  2006cited by this paper
• Mass spectrometry technologies for proteomics.

  2006cited by this paper
• Protein and peptide arrays: recent trends and new directions.

  2006cited by this paper
• Reverse-phase protein microarrays for tissue-based analysis.

  2005cited by this paper
• Pegylated, steptavidin-conjugated quantum dots are effective detection elements for reverse-phase protein microarrays.

  2005cited by this paper
• Protein profiling of INS1E cells by two-dimensional gel electrophoresis and mass spectrometry

  2005cited by this paper
• Proteomics strategies for protein identification

  2005cited by this paper
• Activation of peroxisome proliferator-activated receptor-gamma by rosiglitazone protects human islet cells against human islet amyloid polypeptide toxicity by a phosphatidylinositol 3'-kinase-dependent pathway.

  2005cited by this paper
• Glucose-induced changes of multiple mouse islet proteins analysed by two-dimensional gel electrophoresis and mass spectrometry

  2005cited by this paper
• Serum Microarrays for Large Scale Screening of Protein Levels *S

  2005cited by this paper
• Peptide mass fingerprinting.

  2005cited by this paper
• Advances in functional protein microarray technology

  2005cited by this paper
• The continuing evolution of shotgun proteomics.

  2005cited by this paper
• Comparison of Label-free Methods for Quantifying Human Proteins by Shotgun Proteomics*S

  2005cited by this paper
• Protein profiling of human pancreatic islets by two-dimensional gel electrophoresis and mass spectrometry.

  2005cited by this paper
• Integrating global proteomic and genomic expression profiles generated from islet alpha cells: opportunities and challenges to deriving reliable biological inferences.

  2005cited by this paper
• High‐throughput two‐hybrid analysis

  2005cited by this paper
• Pharmacoproteomic approach to the study of drug mode of action, toxicity, and resistance: applications in diabetes and cancer

  2004cited by this paper
• Effect of nutrients, hormones and serum on survival of rat islet beta cells in culture

  2004cited by this paper
• Current two‐dimensional electrophoresis technology for proteomics

  2004cited by this paper
• The molecular scanner: concept and developments.

  2004cited by this paper
• Implications of new proteomics strategies for biology and medicine.

  2004cited by this paper
• HysTag—A Novel Proteomic Quantification Tool Applied to Differential Display Analysis of Membrane Proteins From Distinct Areas of Mouse Brain*

  2004cited by this paper
• Pathophysiology of insulin secretion.

  2004cited by this paper
• Free Fatty Acid-induced β-Cell Defects Are Dependent on Uncoupling Protein 2 Expression*

  2004cited by this paper
• Uncoupling protein 2 and islet function.

  2004cited by this paper
• SELDI-TOF-based serum proteomic pattern diagnostics for early detection of cancer.

  2004cited by this paper
• Effects of dietary fatty acids on insulin sensitivity and secretion

  2004cited by this paper
• Mass spectrometry-based proteomics

  2003cited by this paper
• From words to literature in structural proteomics

  2003cited by this paper
• Protein microarrays: Molecular profiling technologies for clinical specimens

  2003cited by this paper
• A functional proteomics approach to signal transduction.

  2003cited by this paper
• Proteomics as a tool for discovery: proteins implicated in Alzheimer's disease are highly expressed in normal pancreatic islets.

  2003cited by this paper
• Intrauterine programming of fetal islet gene expression in rats—effects of maternal protein restriction during gestation revealed by proteome analysis

  2003cited by this paper
• Global quantitative phosphoprotein analysis using Multiplexed Proteomics technology

  2003cited by this paper
• Microarrays to characterize protein interactions on a whole‐proteome scale

  2003cited by this paper
• Comparative proteome analysis of native differentiated and cultured dedifferentiated human RPE cells.

  2003cited by this paper
• Proteomics in 2002: a year of technical development and wide-ranging applications.

  2003cited by this paper
• Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death.

  2003cited by this paper
• Overcoming technical variation and biological variation in quantitative proteomics

  2003cited by this paper
• Protein chip technology.

  2003cited by this paper
• Proteomic analysis of post-translational modifications

  2003cited by this paper
• Acute effects of fatty acids on insulin secretion from rat and human islets of Langerhans.

  2002cited by this paper
• Bridging genomics and proteomics

  2002cited by this paper
• An NMR approach to structural proteomics

  2002cited by this paper
• Proteome Analysis—A Novel Approach to Understand the Pathogenesis of Type 1 Diabetes Mellitus

  2002cited by this paper
• Expression profiling of palmitate- and oleate-regulated genes provides novel insights into the effects of chronic lipid exposure on pancreatic beta-cell function.

  2002cited by this paper
• Antibody microarrays: promises and problems.

  2002cited by this paper

• The Human Islet: Mini-organ with Mega-impact.

  2021cites this paper
• Perfiles electroforéticos UNI y bidimensionales de las proteínas del plasma seminal y su relación con la fertilidad en toros Brahman en el Meta

  2019cites this paper
• Effects of bone marrow on the microenvironment of the human pancreatic islet: A Protein Profile Approach.

  2017cites this paper
• Microfluidic perfusion systems for secretion fingerprint analysis of pancreatic islets: applications, challenges and opportunities.

  2016cites this paper
• Impact of exposure to low concentrations of nitric oxide on protein profile in murine and human pancreatic islet cells

  2014cites this paper
• Peptidomic profiling of secreted products from pancreatic islet culture results in a higher yield of full-length peptide hormones than found using cell lysis procedures.

  2013cites this paper
• Gender-dependent expression of pancreatic proteins in streptozotocin-induced diabetic rats

  2013cites this paper
• FACULDADE DE CIÊNCIAS FARMACÊUTICAS Programa de Pós-Graduação em Ciência dos Alimentos Área de Bromatologia Análise diferencial do proteoma da polpa de manga (Mangifera indica L.) e identificação de proteínas com variação de abundância durante o amadurecimento pós-colheita

  2011cites this paper
• Unraveling pancreatic islet biology by quantitative proteomics

  2011cites this paper
• Characterization of seedling proteomes and development of markers to distinguish the Brassica A and C genomes.

  2010cites this paper
• Membrane Protein Profiling of Human Islets of Langerhans Using Several Extraction Methods

  2010cites this paper