BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research

• Publication date

  1996-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 8780884
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mutations in the BRCA1 gene in Japanese breast cancer patients

  1996cited by this paper
• Growth retardation and tumour inhibition by BRCA1

  1996cited by this paper
• High allele loss rates at I7q I2‐q2I in breast and ovarian tumors from BRCAI‐linked families

  1995cited by this paper
• Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression

  1995cited by this paper
• Mimosine, a novel inhibitor of DNA replication, binds to a 50 kDa protein in Chinese hamster cells.

  1995cited by this paper
• Hormone-dependent regulation of BRCA1 in human breast cancer cells.

  1995cited by this paper
• High allele loss rates at 17q12-q21 in breast and ovarian tumors from BRCAl-linked families. The Breast Cancer Linkage Consortium.

  1995cited by this paper
• A collaborative survey of 80 mutations in the BRCA1 breast and ovarian cancer susceptibility gene. Implications for presymptomatic testing and screening.

  1995cited by this paper
• Somatic mutations in the BRCA1 gene in sporadic ovarian tumours

  1995cited by this paper
• The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues

  1995cited by this paper
• Aberrant Subcellular Localization of BRCA1 in Breast Cancer

  1995cited by this paper
• Chemotherapy‐Induced Apoptosis in Epithelial Ovarian Cancers

  1995cited by this paper
• Transforming growth factor β1 can induce CIP1/WAF1 expression independent of the p53 pathway in ovarian cancer cells

  1994cited by this paper
• BRCA1 mutations in primary breast and ovarian carcinomas.

  1994cited by this paper
• Risks of cancer in BRCA1-mutation carriers. Breast Cancer Linkage Consortium.

  1994cited by this paper
• A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.

  1994cited by this paper
• Immunocytochemical versus biochemical receptor determination in normal and tumorous tissues of the female reproductive tract and the breast.

  1994cited by this paper
• Transforming growth factor beta 1 can induce CIP1/WAF1 expression independent of the p53 pathway in ovarian cancer cells.

  1994cited by this paper
• p53-dependent apoptosis modulates the cytotoxicity of anticancer agents.

  1993cited by this paper
• The plant amino acid mimosine may inhibit initiation at origins of replication in Chinese hamster cells

  1992cited by this paper
• p53 function and dysfunction.

  1992cited by this paper
• Synchronization of tumor and normal cells from G1 to multiple cell cycles by lovastatin.

  1991cited by this paper
• Human papilloma virus DNAs immortalize normal human mammary epithelial cells and reduce their growth factor requirements.

  1990cited by this paper
• Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types.

  1989cited by this paper
• Immunocytochemical localization of estradiol and progesterone receptors in the monkey ovary throughout the menstrual cycle.

  1988cited by this paper
• Growth regulation of a cellular tumour antigen, p53, in nontransformed cells

  1984cited by this paper

• Aberrant accumulation of phosphorylated BRCA1 in brainstem-type and cortical-type Lewy bodies in Lewy body disease

  2025cites this paper
• The deubiquitinating enzyme Cezanne stabilizes BRCA1 by counteracting APC/C and Ube2S-dependent Lys11-linked ubiquitination

  2025influential citation
• The role of RNF138 in DNA end resection is regulated by ubiquitylation and CDK phosphorylation

  2024cites this paper
• A transcription‐independent mechanism determines rapid periodic fluctuations of BRCA1 expression

  2023cites this paper
• BRCA1: An Endocrine and Metabolic Regulator

  2022cites this paper
• The role of ubiquitin signaling pathway on liver regeneration in rats

  2022cites this paper
• Insights into the non-mitotic functions of Aurora kinase A: more than just cell division

  2019cites this paper
• Aberrant Accumulation of BRCA1 in Alzheimer Disease and Other Tauopathies.

  2019cites this paper
• The BET inhibitor INCB054329 reduces homologous recombination efficiency and augments PARP inhibitor activity in ovarian cancer.

  2018cites this paper
• Non-Coding Variants in BRCA1 and BRCA2 Genes: Potential Impact on Breast and Ovarian Cancer Predisposition

  2018cites this paper
• Aurora A kinase regulates non-homologous end-joining and poly(ADP-ribose) polymerase function in ovarian carcinoma cells

  2017cites this paper
• The BRCA1 tumor suppressor: potential long-range interactions of the BRCA1 promoter and the risk of breast cancer

  2017cites this paper
• Prediction of Disordered RNA, DNA, and Protein Binding Regions Using DisoRDPbind.

  2017cites this paper
• A TGFβ–miR-182–BRCA1 axis controls the mammary differentiation hierarchy

  2016cites this paper
• (Intrinsically disordered) splice variants in the proteome: implications for novel drug discovery

  2016cites this paper
• Breast cancer predisposition gene brca1, pathogenic c61g mutation in mice: synthetic viability in DNA repair and tumour development

  2016cites this paper
• Engineering an analog-sensitive CDK12 cell line using CRISPR/Cas.

  2015cites this paper
• The role of the BARD1 BRCT domains in the DNA damage response

  2014influential citation
• Targeting the BRCA1/2 tumor suppressors.

  2014cites this paper
• Quantitative imaging of single mRNA splice variants in living cells.

  2014cites this paper
• Transgenic expression of BRCA1 disturbs hematopoietic stem and progenitor cells quiescence and function.

  2013cites this paper
• Physiological modulation of endogenous BRCA1 p220 abundance suppresses DNA damage during the cell cycle

  2013cites this paper
• Predictive value of immunohistochemical markers of invasive breast cancer, such as estrogen, progesterone receptors, HER-2, and CK5/6, in young Egyptian women with BRCA1 mutation

  2013cites this paper
• Poly(ADP-ribose) polymerase inhibitors as cancer therapy.

  2013cites this paper
• Differences in 53BP1 and BRCA1 regulation between cycling and non-cycling cells

  2013cites this paper
• Determinants of cell cycle progression in human mammary epithelial MCF12 cells

  2012cites this paper
• IGF-1 and BRCA1 signalling pathways in familial cancer.

  2012cites this paper
• REGULATION OF THE GABPβ PROMOTER AND THE ROLE OF NRF-1 IN MAMMARY EPITHELIAL MORPHOGENESIS

  2012cites this paper
• Identification, Exploitation and Manipulation of BRCA1-Dependent DNA Double-Strand Break and Interstrand Crosslink Repair in Breast and Ovarian Cancer Therapy

  2012cites this paper
• Regulation of the BRCA1 gene by an SRC3/53BP1 complex

  2011cites this paper
• A Conditional Mouse Model for Measuring the Frequency of Homologous Recombination Events In Vivo in the Absence of Essential Genes

  2011cites this paper
• Influence des hormones stéroïdes et potentiel préventif d'un antiprogestatif, l'ulpristal acétate, dans la tumorigenèse liée à la mutation du gène BRCA1

  2011cites this paper
• BRCA1 gene expression in relation to prognostic parameters of breast cancer

  2011cites this paper
• The impact of RNA standardization and heterogeneous gene expression on the results of cDNA array of human breast carcinoma.

  2010cites this paper
• Identification and Characterization of Novel Kinases that Regulate BRCA1 Expression and Function

  2010cites this paper
• Transcriptional Regulation of the Base Excision Repair Pathway by BRCA1*

  2010cites this paper
• Tumor Suppressor BRCA1 Is Expressed in Prostate Cancer and Controls Insulin-like Growth Factor I Receptor (IGF-IR) Gene Transcription in an Androgen Receptor–Dependent Manner

  2009cites this paper
• Therapy of Prostate Cancer Using a Human Antibody Targeting the Type 1 Insulin-Like Growth Factor Receptor (IGF-IR)

  2009cites this paper
• Behind the wheel and under the hood: functions of cyclin-dependent kinases in response to DNA damage.

  2009cites this paper
• The role of BACH1 , BARD1 and TOPBP1 genes in familial breast cancer

  2009cites this paper
• Brca1 is required for embryonic development of the mouse cerebral cortex to normal size by preventing apoptosis of early neural progenitors

  2009cites this paper
• A BRCA1 mutation is not associated with increased indicators of oxidative stress.

  2008cites this paper
• Posttranscriptional regulation of the breast cancer susceptibility gene BRCA1 by the RNA binding protein HuR.

  2008cites this paper
• Synchronization of the cell cycle using Lovastatin

  2008cites this paper
• Sporadic epithelial ovarian cancer: clinical relevance of BRCA1 inhibition in the DNA damage and repair pathway.

  2008cites this paper
• Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brcal, Brca2,

  2007cites this paper
• Regulation of BRCA1 messenger RNA stability in human epithelial cell lines and during cell cycle progression

  2007cites this paper
• Insulin-like Growth Factor-I Controls BRCA1 Gene Expression through Activation of Transcription Factor Sp1

  2007cites this paper
• Isogenic normal basal and luminal mammary epithelial isolated by a novel method show a differential response to ionizing radiation.

  2007cites this paper
• Insulin-like growth factor-I controls BRCA1 gene expression through activation of transcription factor Sp1.

  2007cites this paper
• BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution

  2006cites this paper
• Cell Cycle Control of BRCA 2 '

  2006cites this paper
• Is there more to BARD1 than BRCA1?

  2006cites this paper
• Heregulin-Dependent Delay in Mitotic Progression Requires HER4 and BRCA1

  2006cites this paper
• Mechanisms of tumour suppression and control of genomic integrity by BARD1

  2005cites this paper
• Model of transcriptional regulation of the BRCA1-NBR2 bi-directional transcriptional unit.

  2005cites this paper
• An estrogen receptor-alpha/p300 complex activates the BRCA-1 promoter at an AP-1 site that binds Jun/Fos transcription factors: repressive effects of p53 on BRCA-1 transcription.

  2005cites this paper
• BRCA1 Gene Expression in Breast Cancer: A Correlative Study between Real-time RT-PCR and Immunohistochemistry

  2005cites this paper
• Age at menarche and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers

  2005cites this paper
• BRCA1 promoter methylation in sporadic breast tumors: relationship to gene expression profiles

  2005cites this paper
• Quantitative analysis of BRCA1, BRCA2 and Hmsh2 mRNA expression in colorectal Lieberkühnien adenocarcinomas and matched normal mucosa: relationship with cellular proliferation.

  2005cites this paper
• A Molecular Model For Transcriptional Regulation of BRCA-1 Expression

  2005cites this paper
• BRCA1 Gene Expression in Breast Cancer in Kuwait: Correlation with Prognostic Parameters

  2005cites this paper
• Progesterone induces BRCA1 mRNA decrease, cell cycle alterations and apoptosis in the MCF7 breast cancer cell line.

  2005cites this paper
• Induction of Phosphorylation on BRCAI during the Cell Cycle and after DNA Damage

  2005cites this paper
• Identification of two evolutionarily conserved and functional regulatory elements in intron 2 of the human BRCA1 gene.

  2005cites this paper
• Nuclear Redistribution of BRCAI during Viral Infection 1

  2005cites this paper
• Cell Cycle Dependence of DNA-dependent Protein Kinase Phosphorylation in Response to DNA Double Strand Breaks*

  2005cites this paper
• Cytogenetic evaluation of 20 primary breast carcinomas.

  2004cites this paper
• Molecular Functions of BRCA1 in the DNA Damage Response

  2004cites this paper
• A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint.

  2004cites this paper
• DNA Damage Induces p53-dependent BRCA1 Nuclear Export*

  2004influential citation
• The effects of lycopene on the proliferation of human breast cells and BRCA1 and BRCA2 gene expression.

  2004cites this paper
• Ubiquitination and Proteasomal Degradation of the BRCA1 Tumor Suppressor Is Regulated during Cell Cycle Progression*

  2004cites this paper
• Focused Review Series : BRCA 1 at 10 Years Since Discovery

  2004cites this paper
• Genetic Predisposition to Male and Female Breast Cancer

  2004cites this paper
• Uterus Hyperplasia and Increased Carcinogen-Induced Tumorigenesis in Mice Carrying a Targeted Mutation of the Chk2 Phosphorylation Site in Brca1

  2004cites this paper
• Familial breast and ovarian cancers

  2004cites this paper
• BRCA1 gene in breast cancer

  2003cites this paper
• Breast cancer gene 1 (BRCA1): Role in cell cycle regulation and DNA repair—perhaps through transcription

  2003cites this paper
• Extracellular Matrix Enhances Heregulin-Dependent BRCA1 Phosphorylation and Suppresses BRCA1 Expression through Its C Terminus

  2003cites this paper
• Susceptibility genes in hereditary breast cancer

  2003cites this paper
• Differing effects of breast cancer 1, early onset (BRCA1) and ataxia‐telangiectasia mutated (ATM) mutations on cellular responses to ionizing radiation

  2003cites this paper
• Emerging roles of BRCA1 alternative splicing

  2003cites this paper
• Transcriptional regulation of the murine brca2 gene by CREB/ATF transcription factors.

  2003cites this paper
• Negative Regulation of BRCA1 Gene Expression by HMGA1 Proteins Accounts for the Reduced BRCA1 Protein Levels in Sporadic Breast Carcinoma

  2003cites this paper
• Reduced Brca1 protein expression in 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine–induced rat mammary carcinomas

  2002cites this paper
• Brca1 and differentiation.

  2002cites this paper
• ETS-2 acts as both a transcriptional activator and repressor of target genes in transformed cells /

  2002cites this paper
• Glucose Down-regulates Per1 and Per2mRNA Levels and Induces Circadian Gene Expression in Cultured Rat-1 Fibroblasts* 210

  2002cites this paper
• Inactivation of BRCA 1 and BRCA 2 in Ovarian Cancer

  2002cites this paper
• BRCA-1, BRCA-2 and Hereditary Breast Cancer

  2002cites this paper
• Characterization of the c-MYC-regulated transcriptome by SAGE: Identification and analysis of c-MYC target genes

  2002cites this paper
• Inactivation of BRCA1 and BRCA2 in ovarian cancer.

  2002cites this paper
• BARD1 Induces BRCA1 Intranuclear Foci Formation by Increasing RING-dependent BRCA1 Nuclear Import and Inhibiting BRCA1 Nuclear Export*

  2002cites this paper
• Dominant-negative activity of a Brca1 truncation mutant: effects on proliferation, tumorigenicity in vivo, and chemosensitivity in a mouse ovarian cancer cell line.

  2002cites this paper
• The p53 mutational spectrum associated with BRCA1 mutant ovarian cancer.

  2001cites this paper
• Expression of BRCA1 gene in ewe mammary epithelial cells during pregnancy: regulation by growth hormone and steroid hormones.

  2001cites this paper
• Expression profiles of BRCA1 splice variants in asynchronous and in G1/S synchronized tumor cell lines.

  2001cites this paper
• Localization of human BRCA1 and BRCA2 in non-inherited colorectal carcinomas and matched normal mucosas.

  2001cites this paper