Transcription factor CEBPA has been widely studied for its involvement in hematopoietic cell differentiation and causal role in hematological malignancies. It is shown for the first time that CEBPA also has a causal role in cytokine-induced apoptosis of pancreas β cells.
CEBPA exerts a specific and biologically important proapoptotic role in pancreatic β cells through its downstream network targets
D. Barbagallo,A. Condorelli,S. Piro,N. Parrinello,T. Fløyel,M. Ragusa,A. M. Rabuazzo,J. Størling,F. Purrello,C. Di Pietro,M. Purrello
Published 2014 in Molecular Biology of the Cell
ABSTRACT
PUBLICATION RECORD
- Publication year
2014
- Venue
Molecular Biology of the Cell
- Publication date
2014-08-15
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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