Acute host-mediated endothelial injury after adenoviral gene transfer in normal rabbit arteries: impact on transgene expression and endothelial function.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Circulation Research

• Publication date

  1998-06-29

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1161/01.RES.82.12.1253PMID 9648721
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Adenovirus infection stimulates the Raf/MAPK signaling pathway and induces interleukin-8 expression

  1997cited by this paper
• Vasomotor Dysfunction Early after Exposure of Normal Rabbit Arteries to an Adenoviral Vector

  1997cited by this paper
• Adenoviral gene transfer of nitric oxide synthase: high level expression in human vascular cells.

  1996cited by this paper
• Local adenoviral–mediated expression of recombinant hirudin reduces neointima formation after arterial injury

  1996influential reference
• Nitric oxide reversibly inhibits the migration of cultured vascular smooth muscle cells.

  1996cited by this paper
• Adenovirus-mediated gene transfer into normal rabbit arteries results in prolonged vascular cell activation, inflammation, and neointimal hyperplasia.

  1995cited by this paper
• Endothelium-specific in vivo gene transfer.

  1995cited by this paper
• Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines.

  1995cited by this paper
• A packaging cell line for propagation of recombinant adenovirus vectors containing two lethal gene-region deletions.

  1995cited by this paper
• Neutrophil chemoattractants generated in two phases during reperfusion of ischemic myocardium in the rabbit. Evidence for a role for C5a and interleukin-8.

  1995cited by this paper
• Replication-Deficient Adenovirus Induces Expression of Interleukin-8 by Airway Epithelial Cells In Vitro

  1995cited by this paper
• Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression.

  1995cited by this paper
• In vivo gene transfer into injured carotid arteries. Optimization and evaluation of acute toxicity.

  1995cited by this paper
• Cytostatic gene therapy for vascular proliferative disorders with a constitutively active form of the retinoblastoma gene product

  1995influential reference
• Percutaneous transluminal in vivo gene transfer by recombinant adenovirus in normal porcine coronary arteries, atherosclerotic arteries, and two models of coronary restenosis.

  1994cited by this paper
• Intracellular oxidative stress induced by nitric oxide synthesis inhibition increases endothelial cell adhesion to neutrophils.

  1994cited by this paper
• In Vivo Evaluation of the Safety of Adenovirus-Mediated Transfer of the Human Cystic Fibrosis Transmembrane Conductance Regulator cDNA to the Lung

  1994cited by this paper
• Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver.

  1994cited by this paper
• C5a-induced expression of P-selectin in endothelial cells.

  1994cited by this paper
• Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy.

  1994cited by this paper
• Gene therapy for vascular smooth muscle cell proliferation after arterial injury.

  1994influential reference
• Pharmacology of the endothelium in ischemia-reperfusion and circulatory shock.

  1993cited by this paper
• Assessment of Recombinant Adenoviral Vectors for Hepatic Gene Therapy

  1993cited by this paper
• The expression of CD11/CD18 molecules on rabbit leucocytes: identification of monoclonal antibodies to CD18 and their effect on cellular adhesion processes.

  1993cited by this paper
• Sustained Activation of Vascular Cells and Leukocytes in the Rabbit Aorta After Balloon Injury

  1993cited by this paper
• Inflammatory roles of P-selectin.

  1993cited by this paper
• Neutrophils contribute to hepatic ischemia‐ reperfusion injury by a CD18‐independent mechanism

  1993cited by this paper
• Manipulation of adenovirus vectors.

  1991cited by this paper
• Rapid neutrophil adhesion to activated endothelium mediated by GMP-140

  1990cited by this paper
• An L-arginine/nitric oxide pathway present in human platelets regulates aggregation.

  1990cited by this paper
• Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.

  1989cited by this paper
• Role of endothelium-derived nitric oxide in the regulation of blood pressure.

  1989cited by this paper
• The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium.

  1987cited by this paper
• Neutropenia, inflammation, and the kinetics of transfused neutrophils in rabbits.

  1979cited by this paper
• Antigens and structure of the adenovirus

  1965cited by this paper
• A protein factor responsible for the early cytopathic effect of adenoviruses.

  1958cited by this paper

• Gene Transfer to the Vascular System: Novel Translational Perspectives for Vascular Diseases.

  2020cites this paper
• A Rabbit Model for Testing Helper-Dependent Adenovirus-Mediated Gene Therapy for Vein Graft Atherosclerosis

  2017cites this paper
• Thinking inside and outside the blood vessel: S1P-mediated control of vascular tone and the impact of CMV infection

  2016cites this paper
• Efficient Gene Transfer and Durable Transgene Expression in Grafted Rabbit Veins

  2015cites this paper
• Polymer-based delivering of shRNA to rabbit aortic smooth muscle cells suppressed the expression of IGF-1R in vitro and in vivo.

  2014cites this paper
• Inhibition of neointimal hyperplasia in a rabbit vein graft model following non-viral transfection with human iNOS cDNA

  2013cites this paper
• Gene therapy for the prevention of vein graft disease.

  2013cites this paper
• biphasic liver toxicity in hemophilia A dogs results in short-term phenotypic correction, inhibitor development, and Systemic delivery of an adenoviral vector encoding canine factor VIII

  2013cites this paper
• From gene to epigene-based therapies targeting the vascular endothelium.

  2012cites this paper
• Overexpression of Endothelial Nitric Oxide Synthase Improves Endothelium-Dependent Vasodilation in Arteries Infused with Helper-Dependent Adenovirus

  2012influential citation
• Expression of apolipoprotein A-I in rabbit carotid endothelium protects against atherosclerosis.

  2011cites this paper
• Helper-Dependent Adenovirus Is Superior to First-Generation Adenovirus for Expressing Transgenes in Atherosclerosis-Prone Arteries

  2011cites this paper
• Efficient transgene expression from naked DNA delivered into an arterio‐venous fistula model for kidney dialysis

  2011cites this paper
• Therapeutic strategies for endothelial dysfunction

  2011cites this paper
• Delivery of TFPI-2 using ultrasound with a microbubble agent (SonoVue) inhibits intimal hyperplasia after balloon injury in a rabbit carotid artery model.

  2010cites this paper
• Construction of a novel expression cassette for increasing transgene expression in vivo in endothelial cells of large blood vessels

  2010cites this paper
• Catheter-based adenovirus-mediated anti-monocyte chemoattractant gene therapy attenuates in-stent neointima formation in cynomolgus monkeys.

  2007cites this paper
• The development of viral vectors for targeted gene delivery to atherosclerotic plaques

  2007cites this paper
• Gene therapy and coronary artery bypass grafting: current perspectives.

  2006cites this paper
• Application to Vascular Adventitia of a Nonviral Vector for TIMP-1 Gene Therapy to Prevent Intimal Hyperplasia

  2006cites this paper
• Gene Transfer and the Cardiovascular System

  2005cites this paper
• Gene Therapy for Celebral Arterial Diseases

  2005cites this paper
• Advances towards Cerebrovascular Gene Therapy

  2005cites this paper
• Vascular Endothelium Has a Local Anti-Adenovirus Vector System and Glucocorticoid Optimizes Its Gene Transduction

  2005cites this paper
• nonviral gene transfer into autologous vein grafts Ex vivo electroporation as a potent new strategy for

  2005cites this paper
• Ex vivo electroporation as a potent new strategy for nonviral gene transfer into autologous vein grafts.

  2005cites this paper
• Endothelium-targeted gene and cell-based therapies for cardiovascular disease.

  2004cites this paper
• NF-kappaB activation is required for the development of cardiac hypertrophy in vivo.

  2004cites this paper
• Adenovirus endocytosis and adenoviral gene transfer in cardiovascular and dermatologic disease models

  2004cites this paper
• NF- (cid:1) B activation is required for the development of cardiac hypertrophy in vivo

  2004cites this paper
• ADENOVIRUS ENDOCYTOSIS AND ADENOVIRAL GENE TRANSFER IN CARDIOVASCULAR AND DERMATOLOGIC DISEASE MODELS

  2004cites this paper
• NF-κB activation is required for the development of cardiac hypertrophy in vivo

  2004cites this paper
• Improved Vascular Gene Transfer With a Helper-Dependent Adenoviral Vector

  2004cites this paper
• Overexpression of p53 increases lumen size and blocks neointima formation in porcine interposition vein grafts.

  2004cites this paper
• Inhibition of restenosis by tissue factor pathway inhibitor: in vivo and in vitro evidence for suppressed monocyte chemoattraction and reduced gelatinolytic activity.

  2004cites this paper
• Transient foamy virus vector production by adenovirus vectors

  2004cites this paper
• Appropriate control of ex vivo gene therapy delivering basic fibroblast growth factor promotes successful and safe development of collateral vessels in rabbit model of hind limb ischemia.

  2004cites this paper
• The Emerging Role of Gene Therapy in the Treatment of Cardiovascular Diseases

  2003cites this paper
• Development of targeted viral vectors for cardiovascular gene therapy.

  2003cites this paper
• A Hemodynamic Response to Intravenous Adenovirus Vector Particles Is Caused by Systemic Kupffer Cell-Mediated Activation of Endothelial Cells

  2003cites this paper
• Nonviral Gene Gun Mediated Transfer into the Beating Heart

  2003cites this paper
• Lethal Toxicity, Severe Endothelial Injury, and a Threshold Effect with High Doses of an Adenoviral Vector in Baboons

  2002cites this paper
• Genetic interventions for vein bypass graft disease: a review.

  2002cites this paper
• Clinical trials in vascular gene therapy: the missing piece of the puzzle.

  2002cites this paper
• Platelet-endothelial cell adhesion molecule-1-directed immunotargeting to cardiopulmonary vasculature.

  2002cites this paper
• Gene transfer to coronary artery bypass conduits.

  2002cites this paper
• Effect of adenoviral titer and instillation pressure on gene transfer efficiency to arterial and venous grafts ex-vivo.

  2002cites this paper
• Gene transfer to blood vessels using adenoviral vectors.

  2002cites this paper
• Effect of in vivo gene transfer of nNOS in the PVN on renal nerve discharge in rats.

  2002cites this paper
• Systemic delivery of an adenoviral vector encoding canine factor VIII results in short-term phenotypic correction, inhibitor development, and biphasic liver toxicity in hemophilia A dogs.

  2001cites this paper
• Inclusion of the E3 Region in an Adenoviral Vector Decreases Inflammation and Neointima Formation After Arterial Gene Transfer

  2001cites this paper
• Successful and optimized in vivo gene transfer to rabbit carotid artery mediated by electronic pulse

  2001cites this paper
• Combination of a Brief Irrigation With Tissue Factor Pathway Inhibitor (TFPI) and Adenovirus-Mediated Local TFPI Gene Transfer Additively Reduces Neointima Formation in Balloon-Injured Rabbit Carotid Arteries

  2001cites this paper
• p27-p16 Fusion Gene Inhibits Angioplasty-Induced Neointimal Hyperplasia and Coronary Artery Occlusion

  2001cites this paper
• Neointima Formation After Arterial Gene Transfer Inclusion of the E 3 Region in an Adenoviral Vector Decreases Inflammation and

  2001cites this paper
• Specific LOX-1 Receptor − Identification of Peptides That Target the Endothelial Cell

  2001cites this paper
• Clinical efforts to modulate angiogenesis in the adult: gene therapy versus conventional approaches.

  2001cites this paper
• Identification of Peptides That Target the Endothelial Cell–Specific LOX-1 Receptor

  2001cites this paper
• In vivo myocardial gene transfer: Optimization, evaluation and direct comparison of gene transfer vectors

  2001cites this paper
• Improved Adenoviral Vector for Vascular Gene Therapy: Beneficial Effects on Vascular Function and Inflammation

  2001cites this paper
• Gene therapy for acute diseases.

  2001cites this paper
• Local gene delivery to the vessel wall.

  2001cites this paper
• A Genetically Modified Adenoviral Vector Exhibits Enhanced Gene Transfer of Human Smooth Muscle Cells

  2001cites this paper
• Endothelial dysfunction and inflammation-is there a link?

  2001cites this paper
• Gene transfer of endothelial nitric oxide synthase to pulmonary allografts: impact on acute rejection

  2000cites this paper
• Gene transfer of endothelial nitric oxide synthase alters endothelium-dependent relaxations in aortas from diabetic rabbits

  2000cites this paper
• Antithrombotic strategies in gene therapy

  2000cites this paper
• In vivo gene transfer of endothelial nitric oxide synthase to carotid arteries from hypercholesterolemic rabbits enhances endothelium-dependent relaxations.

  2000cites this paper
• Focal modification of electrical conduction in the heart by viral gene transfer

  2000cites this paper
• Second-generation adenoviral vectors do not prevent rapid loss of transgene expression and vector DNA from the arterial wall.

  2000cites this paper
• Calcium phosphate precipitates augment adenovirus-mediated gene transfer to blood vessels in vitro and in vivo

  2000cites this paper
• Nuclear Factor-kB Regulates Induction of Apoptosis and Inhibitor of Apoptosis Protein-1 Expression in Vascular Smooth Muscle Cells

  1999cites this paper
• Characterization of vascular gene transfer using a novel cationic lipid.

  1999cites this paper
• Angiogenesis induced in muscle by a recombinant adenovirus expressing functional isoforms of basic fibroblast growth factor

  1999cites this paper
• Delivery and Expression of Fluid Shear Stress-Inducible Promoters to the Vessel Wall: Applications for Cardiovascular Gene Therapy

  1999cites this paper
• Adenovirus-mediated local expression of human tissue factor pathway inhibitor eliminates shear stress-induced recurrent thrombosis in the injured carotid artery of the rabbit.

  1999cites this paper
• Nuclear factor-κB regulates induction of apoptosis and inhibitor of apoptosis protein-1 expression in vascular smooth muscle cells

  1999cites this paper
• Is extravasation a Fas-regulated process?

  1999cites this paper
• Nitric oxide synthase gene therapy rapidly reduces adhesion molecule expression and inflammatory cell infiltration in carotid arteries of cholesterol-fed rabbits.

  1999cites this paper
• Gene transfer of endothelial nitric oxide synthase improves nitric oxide-dependent endothelial function in a hypertensive rat model.

  1999cites this paper
• Endothelial injury in vasculitides.

  1999cites this paper
• Adenovirus-mediated delivery of fas ligand inhibits intimal hyperplasia after balloon injury in immunologically primed animals.

  1999cites this paper
• Nuclear factor-kappa B regulates induction of apoptosis and inhibitor of apoptosis protein-1 expression in vascular smooth muscle cells.

  1999cites this paper
• Intravenous administration of recombinant adenoviruses causes thrombocytopenia, anemia and erythroblastosis in rabbits

  1999cites this paper
• Arteries From Normal and Cholesterol-Fed Rabbits In Vivo Gene Transfer of Nitric Oxide Synthase Enhances Vasomotor Function in Carotid

  1998cites this paper
• Lessons from human arteries: how to design a gene therapy strategy for treatment of cardiovascular disease.

  1998cites this paper
• In vivo gene transfer of nitric oxide synthase enhances vasomotor function in carotid arteries from normal and cholesterol-Fed rabbits.

  1998cites this paper