Reciprocal Regulation of the TOR Kinase and ABA Receptor Balances Plant Growth and Stress Response.

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Molecules and Cells

• Publication date

  2018-01-04

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/j.molcel.2017.12.002PMID 29290610PMCID PMC5772982
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Differential TOR activation and cell proliferation in Arabidopsis root and shoot apexes

  2017influential reference
• GTPase ROP2 binds and promotes activation of target of rapamycin, TOR, in response to auxin

  2017influential reference
• Brassinosteriod Insensitive 2 (BIN2) acts as a downstream effector of the Target of Rapamycin (TOR) signaling pathway to regulate photoautotrophic growth in Arabidopsis.

  2017cited by this paper
• To Stimulate or Inhibit? That Is the Question for the Function of Abscisic Acid.

  2017cited by this paper
• Target of Rapamycin Signaling Regulates Metabolism, Growth, and Life Span in Arabidopsis

  2017cited by this paper
• Guard cell sensory systems: recent insights on stomatal responses to light, abscisic acid, and CO2.

  2016cited by this paper
• Abiotic Stress Signaling and Responses in Plants.

  2016influential reference
• OsREM4.1 Interacts with OsSERK1 to Coordinate the Interlinking between Abscisic Acid and Brassinosteroid Signaling in Rice.

  2016cited by this paper
• Co-evolution of Hormone Metabolism and Signaling Networks Expands Plant Adaptive Plasticity.

  2016cited by this paper
• Brassinosteroid/Abscisic Acid Antagonism in Balancing Growth and Stress.

  2016cited by this paper
• The NF-YC–RGL2 module integrates GA and ABA signalling to regulate seed germination in Arabidopsis

  2016cited by this paper
• TOR Signaling and Nutrient Sensing.

  2016cited by this paper
• TOR Signaling Promotes Accumulation of BZR1 to Balance Growth with Carbon Availability in Arabidopsis.

  2016influential reference
• ABA receptor PYL9 promotes drought resistance and leaf senescence

  2016cited by this paper
• Type One Protein Phosphatase 1 and Its Regulatory Protein Inhibitor 2 Negatively Regulate ABA Signaling

  2016cited by this paper
• GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling

  2015cited by this paper
• Aquaporins Contribute to ABA-Triggered Stomatal Closure through OST1-Mediated Phosphorylation

  2015cited by this paper
• Rapid High-pH Reverse Phase StageTip for Sensitive Small-Scale Membrane Proteomic Profiling.

  2015cited by this paper
• Tuning plant signaling and growth to survive salt.

  2015cited by this paper
• Mechanisms of abscisic acid-mediated control of stomatal aperture.

  2015cited by this paper
• Elevated CO2-Induced Responses in Stomata Require ABA and ABA Signaling

  2015cited by this paper
• NLK phosphorylates Raptor to mediate stress-induced mTORC1 inhibition

  2015cited by this paper
• Sequential phosphoproteomic enrichment through complementary metal-directed immobilized metal ion affinity chromatography.

  2014cited by this paper
• Nitric oxide negatively regulates abscisic acid signaling in guard cells by S-nitrosylation of OST1

  2014cited by this paper
• GSK3-like kinases positively modulate abscisic acid signaling through phosphorylating subgroup III SnRK2s in Arabidopsis

  2014cited by this paper
• Identification of Extracellular Signal-regulated Kinase 1 (ERK1) Direct Substrates using Stable Isotope Labeled Kinase Assay-Linked Phosphoproteomics*

  2014cited by this paper
• Making new contacts: the mTOR network in metabolism and signalling crosstalk

  2014cited by this paper
• Molecular basis of nitrate uptake by the plant nitrate transporter NRT1.1

  2014cited by this paper
• The ABA Receptor PYL8 Promotes Lateral Root Growth by Enhancing MYB77-Dependent Transcription of Auxin-Responsive Genes

  2014cited by this paper
• ProteomeXchange provides globally co-ordinated proteomics data submission and dissemination

  2014cited by this paper
• A mesoscale abscisic acid hormone interactome reveals a dynamic signaling landscape in Arabidopsis.

  2014cited by this paper
• BRASSINOSTEROID INSENSITIVE2 Interacts with ABSCISIC ACID INSENSITIVE5 to Mediate the Antagonism of Brassinosteroids to Abscisic Acid during Seed Germination in Arabidopsis[W]

  2014cited by this paper
• Glc-TOR signalling leads transcriptome reprogramming and meristem activation

  2013cited by this paper
• The unique mode of action of a divergent member of the ABA-receptor protein family in ABA and stress signaling

  2013cited by this paper
• Quantitative phosphoproteomics identifies SnRK2 protein kinase substrates and reveals the effectors of abscisic acid action

  2013cited by this paper
• TOR tour to auxin

  2013cited by this paper
• Endodermal ABA Signaling Promotes Lateral Root Quiescence during Salt Stress in Arabidopsis Seedlings[C][W]

  2013cited by this paper
• TOR and S6K1 promote translation reinitiation of uORF‐containing mRNAs via phosphorylation of eIF3h

  2013cited by this paper
• Systemic analysis of inducible target of rapamycin mutants reveal a general metabolic switch controlling growth in Arabidopsis thaliana.

  2013cited by this paper
• Genetics and Phosphoproteomics Reveal a Protein Phosphorylation Network in the Abscisic Acid Signaling Pathway in Arabidopsis thaliana

  2013cited by this paper
• Auxin controls seed dormancy through stimulation of abscisic acid signaling by inducing ARF-mediated ABI3 activation in Arabidopsis

  2013cited by this paper
• Arabidopsis PYR/PYL/RCAR Receptors Play a Major Role in Quantitative Regulation of Stomatal Aperture and Transcriptional Response to Abscisic Acid[C][W]

  2012influential reference
• Anion channels: master switches of stress responses.

  2012cited by this paper
• mTOR signaling in growth control and disease.

  2012cited by this paper
• Intestinal Cell Kinase (ICK) Promotes Activation of mTOR Complex 1 (mTORC1) through Phosphorylation of Raptor Thr-908*

  2012cited by this paper
• Target of Rapamycin Signaling Regulates Metabolism, Growth, and Life Span in Arabidopsis[W][OA]

  2012cited by this paper
• The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling

  2011cited by this paper
• Viral factor TAV recruits TOR/S6K1 signalling to activate reinitiation after long ORF translation

  2011cited by this paper
• News on ABA transport, protein degradation, and ABFs/WRKYs in ABA signaling.

  2011cited by this paper
• Rapamycin and Glucose-Target of Rapamycin (TOR) Protein Signaling in Plants*

  2011influential reference
• Universal and confident phosphorylation site localization using phosphoRS.

  2011cited by this paper
• Arabidopsis decuple mutant reveals the importance of SnRK2 kinases in osmotic stress responses in vivo

  2011cited by this paper
• The molecular basis of ABA-independent inhibition of PP2Cs by a subclass of PYL proteins.

  2011cited by this paper
• Molecular Basis of the Core Regulatory Network in ABA Responses: Sensing, Signaling and Transport

  2010cited by this paper
• Abscisic acid: emergence of a core signaling network.

  2010influential reference
• ABA perception and signalling.

  2010cited by this paper
• Identification and Mechanism of ABA Receptor Antagonism

  2010cited by this paper
• ABI4 Mediates Abscisic Acid and Cytokinin Inhibition of Lateral Root Formation by Reducing Polar Auxin Transport in Arabidopsis[C][W]

  2010cited by this paper
• ERK1/2 Phosphorylate Raptor to Promote Ras-dependent Activation of mTOR Complex 1 (mTORC1)*

  2010cited by this paper
• Early abscisic acid signal transduction mechanisms: newly discovered components and newly emerging questions.

  2010cited by this paper
• A Gate-Latch-Lock Mechanism for Hormone Signaling by Abscisic Acid Receptors

  2009cited by this paper
• Structural basis of abscisic acid signalling

  2009cited by this paper
• In vitro Reconstitution of an ABA Signaling Pathway

  2009cited by this paper
• Arabidopsis mutant deficient in 3 abscisic acid-activated protein kinases reveals critical roles in growth, reproduction, and stress

  2009cited by this paper
• The primary signaling outputs of brassinosteroids are regulated by abscisic acid signaling

  2009cited by this paper
• Gibberellins Regulate Lateral Root Formation in Populus through Interactions with Auxin and Other Hormones[C][W]

  2009cited by this paper
• In vitro reconstitution of an abscisic acid signalling pathway

  2009influential reference
• Activity of guard cell anion channel SLAC1 is controlled by drought-stress signaling kinase-phosphatase pair

  2009cited by this paper
• Abscisic Acid Inhibits Type 2C Protein Phosphatases via the PYR/PYL Family of START Proteins

  2009influential reference
• Regulators of PP2C Phosphatase Activity Function as Abscisic Acid Sensors

  2009cited by this paper
• Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation.

  2008cited by this paper
• AMPK phosphorylation of raptor mediates a metabolic checkpoint.

  2008cited by this paper
• MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

  2008cited by this paper
• Identification of Two Protein Kinases Required for Abscisic Acid Regulation of Seed Germination, Root Growth, and Gene Expression in Arabidopsis[W]

  2007cited by this paper
• Integration of Plant Responses to Environmentally Activated Phytohormonal Signals

  2006cited by this paper
• Arabidopsis TARGET OF RAPAMYCIN Interacts with RAPTOR, Which Regulates the Activity of S6 Kinase in Response to Osmotic Stress Signals

  2005cited by this paper
• An Arabidopsis homolog of RAPTOR/KOG1 is essential for early embryo development.

  2005cited by this paper
• mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events.

  2005cited by this paper
• MUSCLE: multiple sequence alignment with high accuracy and high throughput.

  2004cited by this paper
• ESPript/ENDscript: extracting and rendering sequence and 3D information from atomic structures of proteins

  2003cited by this paper
• An abscisic acid-sensitive checkpoint in lateral root development of Arabidopsis.

  2003cited by this paper

• Inhibition of target of rapamycin signaling suppresses growth and andrographolide biosynthesis in Andrographis paniculata

  2026cites this paper
• LysM receptor‐like kinase MdLYK3 destabilizes the ABA receptors PYR/PYLs to suppress ABA signaling in apple

  2026cites this paper
• ABA receptors: function and post-translational modifications in plants.

  2026cites this paper
• Autophagy-phytohormone crosstalk: a dual-regulation axis in plant development

  2026cites this paper
• The ALS-associated E425K mutation uncouples DNAJC7 from the Hsp70 chaperone cycle.

  2026cites this paper
• Melatonin and sugar signaling in relation to salt and drought stress tolerance in plants.

  2026cites this paper
• Role of abscisic acid receptor PYLs in mediating stress resistance of Zostera marina.

  2026cites this paper
• Genome-Wide Analysis of Nelumbo nucifera UXS Family Genes: Mediating Dwarfing and Aquatic Salinity Tolerance

  2026cites this paper
• Magnesium: An overlooked signalling ion in plant physiology and circadian regulation

  2026cites this paper
• The OsSAPK10-OsPAL1 module contributes to rice blast resistance

  2025cites this paper
• Principles of signal integration in combinatorial stress acclimatization

  2025cites this paper
• Decoding the Growth-Defense Dialectic: TOR signaling and developmental genetics in maize.

  2025cites this paper
• OsPRMT6b balances plant growth and high temperature stress by feedback inhibition of abscisic acid signaling

  2025cites this paper
• Plant chloroplast stress response: insights from mass spectrometry metabolites analysis

  2025cites this paper
• Glycolysis and signal transduction participate in Lycium barbarum in response to NaCl stress through protein phosphorylation

  2025cites this paper
• Target of Rapamycin (TOR): A Master Regulator in Plant Growth, Development, and Stress Responses.

  2025cites this paper
• Stress granule dynamics govern TOR reactivation and growth recovery during post-heat stress adaptation

  2025cites this paper
• Autophagy-Mediated Adaptation: Revealing the Role of Autophagy in Plant Responses to Abiotic Stress

  2025influential citation
• IRE1 Regulates TOR Signaling via RIDD of RAPTOR1b to Coordinate Growth and Stress Adaptation

  2025cites this paper
• ERF026 balances the growth and drought stress response of Medicago sativa L. by regulating jasmonic acid metabolism.

  2025cites this paper
• Two E-clade Protein Phosphatase 2Cs enhance ABA signaling by dephosphorylating ABI1 in Arabidopsis.

  2025cites this paper
• Protein Post-Translational Modifications in Plant Abiotic Stress Responses

  2025cites this paper
• Unveiling the molecular mechanism underlying PSKR-mediated amplification of the ABA signaling in Arabidopsis thaliana

  2025cites this paper
• Protocol for detecting SnRK2 kinase activity in plants by immunoblotting, in-gel assay, band shift, and immunoprecipitation

  2025cites this paper
• Phosphorylation/dephosphorylation-mediated regulation of ABI1/2 activity and stability for fine-tuning ABA signaling.

  2025cites this paper
• Crosstalk and Coordination of TOR, SnRK1, and ABA in Plant Metabolic and Environmental Adaptation.

  2025cites this paper
• Synergistic Enhancement of Plant Drought Tolerance by PYL and ABA—A Review

  2025cites this paper
• Revealing programmed cell death events during flower (petal) senescence.

  2025cites this paper
• Adjustments of plant primary metabolism in the face of climate change

  2025cites this paper
• The endosomal sorting complex protein FYVE4 affects abscisic acid signaling by regulating the stability of abscisic acid receptors.

  2025cites this paper
• FL7 is an ancient ABA-independent inhibitor of PP2C-As regulating plant stress responses

  2025cites this paper
• Target of rapamycin signaling in pea embryos is dependent on glutamine but detached from seed storage protein biosynthesis

  2025influential citation
• The Transcription Factors NFYA1 and GBF3 Jointly Regulate CHS2 to Promote Tangeretin Accumulation and Cold Tolerance in Citrus

  2025cites this paper
• Identification of a novel stomatal opening chemical, PP242, that inhibits early abscisic acid signal transduction in guard cells

  2025influential citation
• Rhizobium-Enhanced Drought Tolerance in Red Kidney Beans Through Modification of Transcriptome and Microbial Communities

  2025cites this paper
• Regulation of vacuole fusion in stomata by dephosphorylation of the HOPS subunit VPS39

  2025influential citation
• Nutrient-driven TOR signalling controls a chromatin-associated complex for orchestrating plant growth and stress tolerance

  2025influential citation
• Light-mediated balances and trade-offs in plant energy and resource management.

  2025cites this paper
• TOR Mediates Stress Responses Through Global Regulation of Metabolome in Plants

  2025influential citation
• Novel effector proteins of the plant heteromeric acetyl-CoA carboxylase.

  2025cites this paper
• Adaptive Traits and Molecular Mechanisms of Rhododendron Species in Changbai Mountains’ Alpine Tundra: A Phenotype–Transcriptome Study

  2025cites this paper
• MYB transcription factors: Acting as molecular switches to regulate different signaling pathways to modulate plant responses to drought stress

  2025cites this paper
• Sugar sensors in plants: Orchestrators of growth, stress tolerance, and hormonal crosstalk.

  2025cites this paper
• Trehalose 6-phosphate activates Target of Rapamycin in plants

  2025influential citation
• Pupylation‐Based Proximity Labeling Unravels a Comprehensive Protein and Phosphoprotein Interactome of the Arabidopsis TOR Complex

  2025cites this paper
• Posttranslational regulation of TOR kinase activity controls resource allocation between plant growth and immunity in Arabidopsis.

  2025cites this paper
• CPK1 activates CNGCs through phosphorylation for Ca2+ signaling to promote root hair growth in Arabidopsis

  2025cites this paper
• The role of PYL genes as core components of abscisic acid signaling in plant abiotic stress response

  2025cites this paper
• Sugars Integrate External and Internal Signals in Regulating Shoot Branching

  2025cites this paper
• The protein kinase SmSnRK2.7 mediates abscisic acid-regulated tanshinone biosynthesis under drought stress in Salvia miltiorrhiza

  2025cites this paper
• Calcium-dependent protein kinases CPK3/4/6/11 and 27 respond to osmotic stress and activate SnRK2s in Arabidopsis.

  2025cites this paper
• Guard cell and whole plant expression of AtTOR improves performance under drought and enhances water use efficiency

  2025cites this paper
• Integrated physiological, transcriptomics, and metabolite analysis reveal photosynthetic toxicity related to the bisphenol A stress response mechanism in pepper (Capsicum annuum L.).

  2025cites this paper
• Phosphoproteomic Profiling Deciphers Heat-Stress-Responsive Mechanisms in Passion Fruit

  2025cites this paper
• At‐RS31 orchestrates hierarchical cross‐regulation of splicing factors and integrates alternative splicing with TOR‐ABA pathways

  2025influential citation
• A Gln alteration influences leaf morphogenesis by mediating gibberellin levels in tobacco.

  2025cites this paper
• Activation of the CNGC2-CNGC4 channel complex by P2K1-mediated phosphorylation links extracellular ATP perception to calcium signaling in plant immunity.

  2025cites this paper
• CPK28-mediated Ca2+ signaling regulates STOP1 localization and accumulation to facilitate plant aluminum resistance

  2025cites this paper
• Unraveling the Role of TARGET OF RAPAMYCIN in the Immune Response of Cucumis sativus to Podosphaera xanthii

  2025cites this paper
• A comprehensive analysis of transcriptome and weighted gene co-expression network (WGCNA) reveals functional genes participating in drought stress response of Jerusalem artichoke (Helianthus tuberosus L.)

  2025cites this paper
• A calcium sensor kinase pathway interacts with the TOR complex to balance growth and salt tolerance in Arabidopsis.

  2025cites this paper
• Research progress on the regulation of plant growth and development by TOR kinase.

  2025cites this paper
• Mapping the Phosphorylation Regulatory Network of Single‐Celled Fibre Elongation Mediated by GhBIN2 in Cotton

  2025cites this paper
• Terrestrial planetary plants: Essential preparations for interstellar migration

  2025cites this paper
• Signalling and regulation of plant development by carbon/nitrogen balance

  2025cites this paper
• Bidirectional regulation between TOR kinase and chloroplasts: emerging connections in photosynthetic organisms.

  2025cites this paper
• Navigating the landscape of plant proteomics.

  2025cites this paper
• Pan-Genome-Based Characterization of the PYL Transcription Factor Family in Populus

  2025cites this paper
• Two pepper subclass II SnRK2 genes positively regulate drought stress response, with differential responsiveness to abscisic acid.

  2025cites this paper
• Systems analysis of long-term heat stress responses in the C4 grass Setaria viridis

  2025cites this paper
• Rice Responses to Abiotic Stress: Key Proteins and Molecular Mechanisms

  2025cites this paper
• Dancing molecules: group A bZIPs and PEBPs at the heart of plant development and stress responses

  2025cites this paper
• Tackling abiotic stress in plants: recent insights and trends

  2025cites this paper
• Effects of seed priming with salicylic acid on cuticular wax deposition in sweet sorghum under drought stress

  2025cites this paper
• The Confluence of TOR signaling and Plant Growth Regulators in Development and Stress Responses.

  2025cites this paper
• Abscisic acid mediates the trade-off between growth and abiotic stress defense

  2025cites this paper
• WITHDRAWN: From Stress to Resilience: Molecular Insights into the Response of Rice to Drought, Salinity, Temperature, and Heavy Metals

  2025cites this paper
• The SnRK1 Kinase: A Key Regulator in Plant Growth, Development, and Environmental Sensing

  2025cites this paper
• A Legionella pneumophila T4SS effector protein (Ravl) triggers mitochondrial fragmentation through phosphoinositide phosphatase activity.

  2025cites this paper
• Protein post-translational modification in plants: Regulation and beyond

  2025cites this paper
• Targeting BnNAC038 improves drought tolerance with low yield penalty in Brassica napus.

  2025cites this paper
• SWEET1‐mediated glucose transport is crucial for energy availability in Arabidopsis

  2025cites this paper
• CmPPR4 gene controls drought resilience in melon ecotypes

  2025cites this paper
• An outlook on mechanisms inciting drought tolerance in cotton (Gossypium hirsutum)

  2025cites this paper
• The Regulatory-associated protein of target of rapamycin 1B (RAPTOR 1B) interconnects with the photoperiod pathway to promote flowering in Arabidopsis

  2025cites this paper
• Dephosphorylation of bZIP59 by PP2A ensures appropriate shade avoidance response in Arabidopsis.

  2024cites this paper
• ZmHSFA2B self‐regulatory loop is critical for heat tolerance in maize

  2024cites this paper
• Integrating Physiology, Transcriptome, and Metabolome Analyses Reveals the Drought Response in Two Quinoa Cultivars with Contrasting Drought Tolerance

  2024cites this paper
• OsPP2C49, a Negative Regulatory Factor in the Abscisic Acid Signaling Pathway, Positively Regulates Grain Yield in Rice

  2024cites this paper
• At-RS31 orchestrates hierarchical cross-regulation of splicing factors and integrates alternative splicing with TOR-ABA pathways

  2024cites this paper
• Advancements in balancing of growth and stress response in horticultural crops

  2024cites this paper
• Integrated transcriptomic and proteomic analysis revealed the regulatory role of 5-azacytidine in kenaf salt stress alleviation.

  2024cites this paper
• Novel curcumin derivatives N17 exert anti-cancer effects through the CSNK1G3/AKT axis in triple-negative breast cancer.

  2024cites this paper
• Soybean PHR1-regulated low phosphorus-responsive GmRALF22 promotes phosphate uptake by stimulating the expression of GmPTs.

  2024cites this paper
• Saussurea involucrata SiLEA5 Enhances Tolerance to Drought Stress in Solanum lycopersicum

  2024cites this paper
• Enhancement of in situ detection and imaging of phytohormones in plant tissues by MALDI-MSI using 2,4-dihydroxy-5-nitrobenzoic acid as a novel matrix.

  2024cites this paper
• The Utilization and Roles of Nitrogen in Plants

  2024cites this paper
• Phytomelatonin: From Intracellular Signaling to Global Horticulture Market

  2024cites this paper
• Integrating Transcriptome and Metabolome Analysis Unveils the Browning Mechanism of Leaf Response to High Temperature Stress in Nicotiana tabacum

  2024cites this paper
• Recent advances in local and systemic nitrate signaling in Arabidopsisthaliana.

  2024cites this paper