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Oxidatively Modified Biomolecules: An Early Biomarker for Acute Coronary Artery Disease

Sarawut Kumphune

Published 2012 in Unknown venue

ABSTRACT

Cardiovascular disease is the worldwide major cause of mortality and morbidity. The 2009 annual report from World Health Organization (WHO) highlighted the mortality rate prediction of the population worldwide that, in 2030, cardiovascular disease will become the major cause of deaths, and the mortality rate will higher than other infectious diseases such as HIV, Tuberculosis, malaria infection (World Heatlh Organization ,2009). Moreover, this report also mentioned that, among cardiovascular diseases, ischemic heart disease and cerebrovascular disease, which were reported as top 2 cause of mortality in 2004, are expected to still be the major cause of death in next 20 years (World Heatlh Organization ,2009). Coronary artery disease is a sequence of pathophysiologic processes in coronary arteries, myocardial ischemia and infarction (Wudkowska et al.2010). Therefore, the early diagnostic of myocardial ischemia and infarction, will lead to the rapid and more effective of medical intervention, and safe the patients’ life. The standard diagnosis of coronary artery disease focuses on clinical assessment such as history of chest pain associated with electrocardiogram (ECG) changes, and elevation of cardiac specific-biochemical markers (Maneewong K. et al.2011).

PUBLICATION RECORD

  • Publication year

    2012

  • Venue

    Unknown venue

  • Publication date

    2012-04-25

  • Fields of study

    Medicine, Environmental Science

  • Identifiers
    DOI 10.5772/32503
  • External record

    Open on Semantic Scholar

  • Source metadata

    Semantic Scholar

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