Association of CAV1/CAV2 genomic variants with primary open-angle glaucoma overall and by gender and pattern of visual field loss.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Ophthalmology (Rochester, Minn.)

• Publication date

  2014-02-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.ophtha.2013.09.012PMID 24572674PMCID PMC3937766
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2016cited by this paper
• Soluble Guanylate Cyclase α1–Deficient Mice: A Novel Murine Model for Primary Open Angle Glaucoma

  2013cited by this paper
• Primary open-angle glaucoma vs normal-tension glaucoma: the vascular perspective.

  2013cited by this paper
• The NEIGHBOR Consortium Primary Open-Angle Glaucoma Genome-wide Association Study: Rationale, Study Design, and Clinical Variables

  2013cited by this paper
• Regulation of eNOS in caveolae.

  2012influential reference
• Lack of association of SNP rs4236601 near CAV1 and CAV2 with POAG in a Saudi cohort

  2012cited by this paper
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  2012cited by this paper
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  2012cited by this paper
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  2012cited by this paper
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  2012cited by this paper
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  2011cited by this paper
• Endothelial nitric oxide synthase gene variants and primary open-angle glaucoma: interactions with hypertension, alcohol intake, and cigarette smoking.

  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
• Chromosome 7q31 POAG locus: ocular expression of caveolins and lack of association with POAG in a US cohort

  2011cited by this paper
• Initial parafoveal versus peripheral scotomas in glaucoma: risk factors and visual field characteristics.

  2011cited by this paper
• Endothelial-specific overexpression of caveolin-1 accelerates atherosclerosis in apolipoprotein E-deficient mice.

  2010cited by this paper
• Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma

  2010influential reference
• Endothelial nitric oxide synthase gene variants and primary open-angle glaucoma: interactions with sex and postmenopausal hormone use.

  2010cited by this paper
• Primary open-angle glaucoma.

  2009cited by this paper
• Characterization of soluble guanylate cyclase in NO-induced increases in aqueous humor outflow facility and in the trabecular meshwork.

  2009cited by this paper
• Chronic NOS inhibition prevents adverse lung remodeling and pulmonary arterial hypertension in caveolin-1 knockout mice.

  2008cited by this paper
• Retinal ganglion cell protection by 17‐β‐estradiol in a mouse model of inherited glaucoma

  2007cited by this paper
• Visual Field Loss Morphology in High- and Normal-Tension Glaucoma

  2006cited by this paper
• The number of people with glaucoma worldwide in 2010 and 2020

  2006cited by this paper
• Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies

  2006cited by this paper
• [Reading performance in patients with central visual field disturbance due to glaucoma].

  2006cited by this paper
• Vascular cell signaling by membrane estrogen receptors.

  2005influential reference
• Transforming growth factor-beta receptors localize to caveolae and regulate endothelial nitric oxide synthase in normal human endothelial cells.

  2005cited by this paper
• Vascular cell signaling by membrane estrogen receptors.

  2005cited by this paper
• Transforming growth factor-β receptors localize to caveolae and regulate endothelial nitric oxide synthase in normal human endothelial cells

  2005cited by this paper
• Shear stress-induced c-fos activation is mediated by Rho in a calcium-dependent manner.

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  2002cited by this paper
• The effect of visual field defects on driving performance: a driving simulator study.

  2002cited by this paper
• Presence of oestrogen receptor type β in human retina

  2001cited by this paper
• Endometrial and myometrial expression of nitric oxide synthase isoforms in pre- and postmenopausal women.

  1999cited by this paper
• Shear stress and the endothelium.

  1998cited by this paper
• Dissecting the Interaction between Nitric Oxide Synthase (NOS) and Caveolin

  1997cited by this paper
• Identification of a Gene That Causes Primary Open Angle Glaucoma

  1997cited by this paper
• Direct Interaction of Endothelial Nitric-oxide Synthase and Caveolin-1 Inhibits Synthase Activity*

  1997cited by this paper
• Number of people with glaucoma worldwide.

  1996cited by this paper
• A modified Bonferroni method for discrete data.

  1990cited by this paper
• A modified Bonferroni method for discrete data.

  1990cited by this paper
• Comparison of visual field defects in normal-tension glaucoma and high-tension glaucoma.

  1986cited by this paper
• Comparison of visual field defects in the low-tension glaucomas with those in the high-tension glaucomas.

  1984cited by this paper
• A comparative study of visual field defects seen in patients with low-tension glaucoma and chronic simple glaucoma.

  1983cited by this paper
• Visual field defects in low-tension glaucoma. Comparison of defects in low-tension glaucoma and chronic open angle glaucoma.

  1982cited by this paper

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• Risk Factors and Genetic Markers Associated with the Development and Progression of Glaucoma: A Review

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• Trabecular meshwork: A pivotal target for evolving glaucoma treatments.

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