A 50-Year Personal Journey: Location, Gene Expression, and Circadian Rhythms.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Cold Spring Harbor Perspectives in Biology

• Publication date

  2017-06-09

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1101/cshperspect.a032516PMID 28600396PMCID PMC5710103
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The discoveries of molecular mechanisms for the circadian rhythm: The 2017 Nobel Prize in Physiology or Medicine

  2018cited by this paper
• Failure to reproduce period-dependent song cycles in Drosophila is due to poor automated pulse-detection and low-intensity courtship

  2017cited by this paper
• RNA-seq analysis of Drosophila clock and non-clock neurons reveals neuron-specific cycling and novel candidate neuropeptides

  2017cited by this paper
• The two‐process model of sleep regulation: a reappraisal

  2016cited by this paper
• Circadian Neuron Feedback Controls the Drosophila Sleep-Activity Profile

  2016cited by this paper
• Molecular mechanisms at the core of the plant circadian oscillator

  2016cited by this paper
• Evolution of KaiC-Dependent Timekeepers: A Proto-circadian Timing Mechanism Confers Adaptive Fitness in the Purple Bacterium Rhodopseudomonas palustris

  2016cited by this paper
• Transplantability of a circadian clock to a noncircadian organism

  2015cited by this paper
• A circadian gene expression atlas in mammals: Implications for biology and medicine

  2014cited by this paper
• Studying circadian rhythms in Drosophila melanogaster.

  2014cited by this paper
• Reported Drosophila courtship song rhythms are artifacts of data analysis

  2014cited by this paper
• Neuronal Machinery of Sleep Homeostasis in Drosophila

  2014cited by this paper
• Circadian rhythm of hyperoxidized peroxiredoxin II is determined by hemoglobin autoxidation and the 20S proteasome in red blood cells

  2014cited by this paper
• Peroxiredoxins are conserved markers of circadian rhythms

  2012cited by this paper
• The structure of the eukaryotic ribosome at 3.0 A resolution. This entry contains ribosomal RNA and ions of the 40S subunit, ribosome A

  2011cited by this paper
• The intronome of budding yeasts.

  2011cited by this paper
• Circadian Clocks in Human Red Blood Cells

  2010cited by this paper
• Circadian rhythms persist without transcription in a eukaryote

  2010cited by this paper
• A role for casein kinase 2 in the mechanism underlying circadian temperature compensation.

  2009cited by this paper
• The Implications of Multiple Circadian Clock Origins

  2009cited by this paper
• Reconstitution of Circadian Oscillation of Cyanobacterial KaiC Phosphorylation in Vitro

  2005cited by this paper
• Origin and evolution of circadian clock genes in prokaryotes

  2003cited by this paper
• Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime

  2002cited by this paper
• Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau.

  2000cited by this paper
• Correlates of sleep and waking in Drosophila melanogaster.

  2000cited by this paper
• Drosophila CRY Is a Deep Brain Circadian Photoreceptor rhythms

  2000cited by this paper
• A unique circadian-rhythm photoreceptor.

  2000cited by this paper
• Drosophila CRY is a deep brain circadian photoreceptor.

  2000cited by this paper
• Rest in Drosophila is a sleep-like state.

  2000cited by this paper
• Drosophila cryptochromes: A unique circadian-rhythm photoreceptor

  2000cited by this paper
• A serum shock induces circadian gene expression in mammalian tissue culture cells.

  1998cited by this paper
• CYCLE is a second bHLH-PAS clock protein essential for circadian rhythmicity and transcription of Drosophila period and timeless.

  1998cited by this paper
• Expression of a gene cluster kaiABC as a circadian feedback process in cyanobacteria.

  1998cited by this paper
• A mutant Drosophila homolog of mammalian Clock disrupts circadian rhythms and transcription of period and timeless.

  1998cited by this paper
• The Drosophila clock gene double-time encodes a protein closely related to human casein kinase Iepsilon.

  1998cited by this paper
• The cryb mutation identifies cryptochrome as a circadian photoreceptor in Drosophila.

  1998cited by this paper
• Role of the CLOCK protein in the mammalian circadian mechanism.

  1998cited by this paper
• double-time is a novel Drosophila clock gene that regulates PERIOD protein accumulation.

  1998cited by this paper
• CRY, a Drosophila clock and light-regulated cryptochrome, is a major contributor to circadian rhythm resetting and photosensitivity.

  1998cited by this paper
• Resonating circadian clocks enhance fitness in cyanobacteria.

  1998cited by this paper
• The Drosophila Clock Gene double-time Encodes a Protein Closely Related to Human Casein Kinase Iε

  1998cited by this paper
• Positional cloning of the mouse circadian clock gene.

  1997cited by this paper
• Functional identification of the mouse circadian Clock gene by transgenic BAC rescue.

  1997cited by this paper
• Isolation of timeless by PER Protein Interaction: Defective Interaction Between timeless Protein and Long-Period Mutant PERL

  1995cited by this paper
• Positional Cloning and Sequence Analysis of the Drosophila Clock Gene, timeless

  1995cited by this paper
• Suppression of PERIOD protein abundance and circadian cycling by the Drosophila clock mutation timeless.

  1995cited by this paper
• Rhythmic Expression of timeless: A Basis for Promoting Circadian Cycles in period Gene Autoregulation

  1995cited by this paper
• Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior.

  1994cited by this paper
• Constitutive overexpression of the Drosophila period protein inhibits period mRNA cycling.

  1994cited by this paper
• Loss of circadian behavioral rhythms and per RNA oscillations in the Drosophila mutant timeless.

  1994cited by this paper
• Synthesis of nitrogenase in mutants of the cyanobacterium Anabaena sp. strain PCC 7120 affected in heterocyst development or metabolism

  1992cited by this paper
• The period gene encodes a predominantly nuclear protein in adult Drosophila

  1992cited by this paper
• Circadian oscillations in period gene mRNA levels are transcriptionally regulated.

  1992cited by this paper
• Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels

  1990cited by this paper
• The Drosophila single-minded gene encodes a nuclear protein with sequence similarity to the per gene product.

  1988cited by this paper
• Behaviour modification by in vitro mutagenesis of a variable region within the period gene of Drosophila

  1987cited by this paper
• The period clock locus of D. melanogaster codes for a proteoglycan.

  1986cited by this paper
• A Drosophila Minute gene encodes a ribosomal protein

  1985cited by this paper
• Sequence, structure, and codon preference of the Drosophila ribosomal protein 49 gene

  1984cited by this paper
• Molecular analysis of the period locus in Drosophila melanogaster and identification of a transcript involved in biological rhythms.

  1984cited by this paper
• Timing of human sleep: recovery process gated by a circadian pacemaker.

  1984cited by this paper
• Restoration of circadian behavioural rhythms by gene transfer in Drosophila

  1984cited by this paper
• P-element transformation with period locus DNA restores rhythmicity to mutant, arrhythmic Drosophila melanogaster.

  1984cited by this paper
• Molecular genetics of a biological clock in Drosophila.

  1984cited by this paper
• Molecular mapping of genetic and chromomeric units in Drosophila melanogaster.

  1983cited by this paper
• Molecular Genetics of the Bithorax Complex in Drosophila melanogaster

  1983cited by this paper
• Chromosomal walking and jumping to isolate DNA from the Ace and rosy loci and the bithorax complex in Drosophila melanogaster.

  1983cited by this paper
• A two process model of sleep regulation.

  1982cited by this paper
• Genetic transformation of Drosophila with transposable element vectors.

  1982cited by this paper
• Transposition of cloned P elements into Drosophila germ line chromosomes.

  1982cited by this paper
• The effect of temperature-sensitive RNA mutants on the transcription products from cloned ribosomal protein genes of yeast.

  1981cited by this paper
• Isolation and sequence of the gene for actin in Saccharomyces cerevisiae.

  1980cited by this paper
• Circadian rhythm mutations in Drosophila melanogaster affect short-term fluctuations in the male's courtship song.

  1980cited by this paper
• Isolation and mapping of a cloned ribosomal protein gene of Drosophila melanogaster

  1980cited by this paper
• R-looping and structural gene indentification of recombinant DNA.

  1979cited by this paper
• Isolation of cloned DNA sequences containing ribosomal protein genes from Saccharomyces cerevisiae.

  1979cited by this paper
• Isolation of yeast histone genes H2A and H2B.

  1979cited by this paper
• Very long-lived messenger RNA in ovaries of Xenopus laevis.

  1977cited by this paper
• Regulation of a set of abundant mRNA sequences.

  1977cited by this paper
• Number and distribution of polyadenylated RNA sequences in yeast.

  1977cited by this paper
• Coordinate regulation of the synthesis of eukaryotic ribosomal proteins.

  1976cited by this paper
• Genetics of acetylcholinesterase in Drosophila melanogaster.

  1976cited by this paper
• Fate mapping of nervous system and other internal tissues in genetic mosaics of Drosophila melanogaster.

  1976cited by this paper
• Analysis of the C-value paradox by molecular hybridization.

  1974cited by this paper
• Three abundance classes in HeLa cell messenger RNA

  1974cited by this paper
• Polynucleotide sequences in eukaryotic DNA and RNA that form ribonuclease-resistant complexes with polyuridylic acid.

  1974cited by this paper
• Polyadenylic acid-containing RNA in Xenopus laevis oocytes.

  1974cited by this paper
• Reiteration frequency of duck haemoglobin genes.

  1973cited by this paper
• Relationship between Protein Synthesis and RNA Content in Skeletal Muscle

  1973cited by this paper
• Formation of membrane-bound polyribosomes.

  1972cited by this paper
• Membrane-associated protein synthesis of mammalian cells. I. The two classes of membrane-associated ribosomes.

  1971cited by this paper
• Clock mutants of Drosophila melanogaster.

  1971cited by this paper
• Membrane-associated protein synthesis of mammalian cells. II. Isopycnic separation of membrane-bound polyribosomes.

  1971cited by this paper
• Enzymatic synthesis of nucleic acidlike polynucleotides.

  1955cited by this paper
• ON TEMPERATURE INDEPENDENCE IN THE CLOCK SYSTEM CONTROLLING EMERGENCE TIME IN DROSOPHILA.

  1954cited by this paper

• Circadian Regulation of Neuronal Membrane Capacitance—Mechanisms and Implications for Neural Computation and Behavior

  2025cites this paper
• The clockwork macrophage: timing in innate immunity.

  2025cites this paper
• Sleep and Chronobiology as a Key to Understand Cluster Headache

  2023cites this paper
• Circadian dysfunction and Alzheimer's disease – An updated review

  2022cites this paper
• Statistical mechanics of clock gene networks underlying circadian rhythms

  2021cites this paper
• Circadian Organelles: Rhythms at All Scales

  2021cites this paper
• Deciphering the Interacting Mechanisms of Circadian Disruption and Alzheimer’s Disease

  2021cites this paper
• Genetic Engineering of Novel Products of Health Significance: Recombinant DNA Technology

  2020cites this paper
• Food as circadian time cue for appetitive behavior

  2020cites this paper
• Circadian and Sleep Dysfunction in Alzheimer's Disease.

  2020cites this paper
• Expansion of the circadian transcriptome in Brassica rapa and genome-wide diversification of paralog expression patterns

  2020cites this paper
• FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora

  2019cites this paper
• The Mammalian Circadian Timing System and the Suprachiasmatic Nucleus as Its Pacemaker

  2019cites this paper
• The discoveries of molecular mechanisms for the circadian rhythm: The 2017 Nobel Prize in Physiology or Medicine

  2018cites this paper
• Circadian Clock Gene Expression and Drug/Toxicant Interactions as Novel Targets of Chronopharmacology and Chronotoxicology

  2018cites this paper
• [Nobel time for the circadian clock - Nobel Prize in Medicine 2017: Jeffrey C. Hall, Michael Rosbash and Michael W. Young].

  2018cites this paper