Regulation of gene expression by glucocorticoids.

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Annual Review of Physiology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1146/ANNUREV.PH.51.030189.003343PMID 2540703
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mechanism of glucocorticoid receptor down-regulation by glucocorticoids.

  1988cited by this paper
• Estrogen-dependent in vitro transcription from the vitellogenin promoter in liver nuclear extracts.

  1988cited by this paper
• Steroid receptor-mediated inhibition of rat prolactin gene expression does not require the receptor DNA-binding domain.

  1988cited by this paper
• Evidence for intracellular association of the glucocorticoid receptor with the 90-kDa heat shock protein.

  1988cited by this paper
• A region in the steroid binding domain determines formation of the non-DNA-binding, 9 S glucocorticoid receptor complex.

  1988cited by this paper
• Glucocorticoid induction of the rat tryptophan oxygenase gene is mediated by two widely separated glucocorticoid‐responsive elements.

  1987cited by this paper
• Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor.

  1987cited by this paper
• Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene.

  1987cited by this paper
• pBR322 contains glucocorticoid regulatory element DNA consensus sequences.

  1987cited by this paper
• Tissue-specific regulation of glucocorticoid receptor mRNA by dexamethasone.

  1987cited by this paper
• Steroid-dependent interaction of transcription factors with the inducible promoter of mouse mammary tumor virus in vivo.

  1987cited by this paper
• Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement

  1987cited by this paper
• Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor

  1987cited by this paper
• Application of a protein-blotting procedure to the study of human glucocorticoid receptor interactions with DNA.

  1987cited by this paper
• Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor.

  1987cited by this paper
• Biochemistry, molecular biology, and physiology of the glucocorticoid receptor.

  1987cited by this paper
• Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor.

  1987cited by this paper
• Glucocorticoid receptor mutants that define a small region sufficient for enhancer activation.

  1987cited by this paper
• Oestrogen and glucocorticoid responsive elements are closely related but distinct

  1987cited by this paper
• A DNA sequence of 15 base pairs is sufficient to mediate both glucocorticoid and progesterone induction of gene expression.

  1987cited by this paper
• Domains of the glucocorticoid receptor involved in specific and nonspecific deoxyribonucleic acid binding, hormone activation, and transcriptional enhancement.

  1987cited by this paper
• Interaction of RNA with transformed glucocorticoid receptor. II. Identification of the RNA as transfer RNA.

  1987cited by this paper
• Molybdate-stabilized nonactivated glucocorticoid-receptor complexes contain a 90-kDa non-steroid-binding phosphoprotein that is lost on activation.

  1986cited by this paper
• The mouse glucocorticoid receptor: mapping of functional domains by cloning, sequencing and expression of wild‐type and mutant receptor proteins.

  1986cited by this paper
• Distinct sequence elements involved in the glucocorticoid regulation of the mouse mammary tumor virus promoter identified by linker scanning mutagenesis.

  1986cited by this paper
• Potential metal-binding domains in nucleic acid binding proteins.

  1986cited by this paper
• The c-erb-A gene encodes a thyroid hormone receptor

  1986cited by this paper
• Steroid-free glucocorticoid receptor binds specifically to mouse mammary tumour virus DNA

  1986cited by this paper
• The c-erb-A protein is a high-affinity receptor for thyroid hormone

  1986cited by this paper
• Gene regulation by proteins acting nearby and at a distance

  1986cited by this paper
• Glucocorticoid receptors lacking hormone-binding activity are bound in nuclei of ATP-depleted cells

  1986cited by this paper
• Down-regulation of glucocorticoid receptor mRNA by glucocorticoid hormones and recognition by the receptor of a specific binding sequence within a receptor cDNA clone.

  1986cited by this paper
• A superfamily of potentially oncogenic hormone receptors.

  1986cited by this paper
• The chicken oestrogen receptor sequence: homology with v‐erbA and the human oestrogen and glucocorticoid receptors.

  1986cited by this paper
• Receptors for glucocorticosteroid and progesterone recognize distinct features of a DNA regulatory element.

  1986cited by this paper
• Glucocorticoid inhibition of transcription from episomal proopiomelanocortin gene promoter.

  1986cited by this paper
• Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA.

  1986cited by this paper
• Functional domains of the human glucocorticoid receptor.

  1986cited by this paper
• In vivo protein–DNA interactions in a glucocorticoid response element require the presence of the hormone

  1986cited by this paper
• Multiple hormone-inducible enhancers as mediators of differential transcription

  1986cited by this paper
• Regulation of epidermal growth factor receptors by glucocorticoids during the cell cycle in HeLa S3 cells.

  1986cited by this paper
• Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product

  1985cited by this paper
• Steroid receptor regulated transcription of specific genes and gene networks.

  1985cited by this paper
• Primary structure and expression of a functional human glucocorticoid receptor cDNA

  1985cited by this paper
• Steroid hormone regulation of gene expression.

  1985cited by this paper
• Glucocorticoid and progesterone receptors bind to the same sites in two hormonally regulated promoters

  1985cited by this paper
• Hormonal regulation of the bovine prolactin promoter in rat pituitary tumor cells.

  1985cited by this paper
• The common 90‐kd protein component of non‐transformed ‘8S’ steroid receptors is a heat‐shock protein.

  1985cited by this paper
• Glucocorticoid receptor binding and activation of a heterologous promoter by dexamethasone by the first intron of the human growth hormone gene

  1985cited by this paper
• Repetitive zinc‐binding domains in the protein transcription factor IIIA from Xenopus oocytes.

  1985cited by this paper
• Steroid hormone receptors and the nucleus.

  1985cited by this paper
• Evidence that the 90-kDa phosphoprotein associated with the untransformed L-cell glucocorticoid receptor is a murine heat shock protein.

  1985cited by this paper
• DNA sequences involved in the regulation of gene expression by glucocorticoid hormones.

  1984cited by this paper
• The mouse mammary tumor virus model in studies of glucocorticoid regulation.

  1984cited by this paper
• Glucocorticoid regulation of pro-opiomelanocortin gene transcription in the rat pituitary.

  1984cited by this paper
• Evidence for microheterogeneity in the structure of human glucocorticoid receptors.

  1984cited by this paper
• Common non-hormone binding component in non-transformed chick oviduct receptors of four steroid hormones

  1984cited by this paper
• Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene

  1984cited by this paper
• Glucocorticoid-receptor complexes in rat thymus cells. Rapid kinetic behavior and a cyclic model.

  1984cited by this paper
• Tissue‐specific DNaseI hypersensitive sites in the 5′‐flanking sequences of the tryptophan oxygenase and the tyrosine aminotransferase genes.

  1984cited by this paper
• Control of gene expression by glucocorticoid hormones.

  1984cited by this paper
• Sequences in the promoter region of the chicken lysozyme gene required for steroid regulation and receptor binding.

  1984cited by this paper
• Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element.

  1984cited by this paper
• Transcription initiation of transfected mouse mammary tumor virus LTR DNA is regulated by glucocorticoid hormones.

  1983cited by this paper
• Subfragments of the large terminal repeat cause glucocorticoid-responsive expression of mouse mammary tumor virus and of an adjacent gene.

  1983cited by this paper
• The glucocorticoid receptor in GH1 cells. Evidence from dense amino acid labeling and whole cell studies for an equilibrium model explaining the influence of hormone on the intracellular distribution of receptor.

  1983cited by this paper
• Glucocorticoid regulation of mouse mammary tumor virus: identification of a short essential DNA region.

  1983cited by this paper
• Gene regulation: Enhancer elements in immunoglobulin genes

  1983cited by this paper
• The glucocorticoid receptor binds to defined nucleotide sequences near the promoter of mouse mammary tumour virus

  1983cited by this paper
• Enhancer elements in immunoglobulin genes.

  1983cited by this paper
• Enhancer elements.

  1983cited by this paper
• Characterization of nonactivated and activated glucocorticoid-receptor complexes from intact rat thymus cells.

  1983cited by this paper
• Subunit dissociation as a possible mechanism of glucocorticoid receptor activation.

  1983cited by this paper
• Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region.

  1983cited by this paper
• DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo.

  1983cited by this paper
• Regulation of mouse mammary tumor virus gene expression by glucocorticoid hormones.

  1983cited by this paper
• Regulation of mouse mammary tumor virus gene expression by glucocorticoid hormones.

  1983cited by this paper
• Identification of modified forms of human glucocorticoid receptors during the cell cycle.

  1982cited by this paper
• Glucocorticoid receptors and the cell cycle: evidence that the accumulation of glucocorticoid receptors during the S phase of the cell cycle is dependent on ribonucleic acid and protein synthesis.

  1982cited by this paper
• Specific binding of the glucocorticoid-receptor complex to the mouse mammary tumor proviral promoter region.

  1982cited by this paper
• Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment whose transcription is regulated by glucocorticoids in vivo.

  1981cited by this paper
• Glucocorticoids regulate the glucocorticoid receptor in the AtT-20 cell.

  1981cited by this paper
• Dexamethasone 21-mesylate: an affinity label of glucocorticoid receptors from rat hepatoma tissue culture cells.

  1981cited by this paper
• Activation and chromatographic properties of the AtT-20 mouse pituitary tumor cell line glucocorticoid receptor.

  1981cited by this paper
• Regulation of glucocorticoid receptors by glucocorticoids in cultured HeLa S3 cells.

  1981cited by this paper
• Correlation between glucocorticoid receptor and cytolytic response of murine lymphoid cell lines.

  1979cited by this paper
• Alteration in glucocorticoid binding site number during the cell cycle in HeLa cells

  1977cited by this paper
• Dexamethasone-mediated induction of mouse mammary tumor virus RNA: a system for studying glucocorticoid action.

  1975cited by this paper
• Control of specific gene expression in higher organisms. Expression of mammalian genes may be controlled by repressors acting on the translation of messenger RNA.

  1969cited by this paper
• CELL CYCLE EVENTS IN THE HYDROCORTISONE REGULATION OF ALKALINE PHOSPHATASE IN HELA S3 CELLS

  1969cited by this paper

• Cortisol controls endoplasmic reticulum stress and hypoxia dependent regulation of insulin receptor and related genes expression in HEK293 cells

  2023cites this paper
• Multiplexed Membrane Signaling by Glucocorticoids.

  2022cites this paper
• Betamethasone induces potent immunosuppression and reduces HIV infection in a PBMC in vitro model

  2020cites this paper
• Organochlorine pesticides: Agrochemicals with potent endocrine-disrupting properties in fish.

  2020cites this paper
• Chapter 12 – Pharmacology and Drug Therapy: Nonbiologic Therapies

  2016cites this paper
• Cortisol regulates sodium homeostasis by stimulating the transcription of sodium-chloride transporter (NCC) in zebrafish (Danio rerio).

  2016cites this paper
• Mechanisms of cortisol action in fish hepatocytes.

  2016cites this paper
• A vertebrate-conserved cis-regulatory module for targeted expression in the main hypothalamic regulatory region for the stress response

  2014cites this paper
• Role of glucocorticoid in developmental programming: evidence from zebrafish.

  2013cites this paper
• The Role of Glucocorticoid Receptor Signaling in Zebrafish Development

  2013cites this paper
• Title : Characterization and the Effects of Stress on Glucocorticoid Receptors in the Brains of Chinook Salmon ( Oncorhynchus tshawytscha )

  2012cites this paper
• PHARMACOLOGY AND DRUG THERAPY

  2011cites this paper
• THE ADRENAL GLAND

  2009cites this paper
• Prostaglandin endoperoxide synthase types 1 and 2: Ontogenetic expression and effects of inhibition on the basal and estrogen stimulated fetal ovine hypothalamus -pituitary adrenal axis

  2008cites this paper
• Bacterial Autoinducer Derived 4-Quinolones as Novel Immune Modulators

  2007cites this paper
• Long-term effects of perinatal glucocorticoid treatment on the heart

  2007cites this paper
• Topical Corticosteroids in the Treatment of Irritant Dermatitis

  2007cites this paper
• Human Promyeloic Leukemia Cells Glucocorticoid Receptor Expression during Differentiation of Updated

  2006cites this paper
• Post-transcriptional modulation of IL-6 and IL-8 responses in structural airway cells

  2006cites this paper
• Androgen and Glucocorticoid Receptors in the Stroma and Epithelium of Prostatic Hyperplasia and Carcinoma 1

  2005cites this paper
• 46 – CORTICOSTEROID USE IN SYSTEMIC LUPUS ERYTHEMATOSUS

  2004cites this paper
• New Hypotheses to Guide Future Antidepressant Drug Development

  2004cites this paper
• The use of corticosteroids to treat ocular inflammation.

  2004cites this paper
• EFFETS DES GLUCOCORTICOIDES SUR LA MISE EN PLACE DES CENTRES D'OSSIFICATION CHEZ L'EMBRYON DE RAT. Implication de certains g

  2004cites this paper
• Neuroprotection: a realistic goal for aged brain?

  2004cites this paper
• Distribution of 1 lj-Hydroxysteroid Dehydrogenase along the Rabbit Nephron

  2003cites this paper
• 26. Immunomodulation and immunotherapy: drugs, cytokines, cytokine receptors, and antibodies.

  2003cites this paper
• 26 Multi-site tlierapeutic modaiities for infiammatory bowel diseases - meclianisms of action

  2003cites this paper
• Multi-site therapeutic modalities for inflammatory bowel diseases — mechanisms of action

  2003cites this paper
• Respuesta al tratamiento glucocorticoideo en el asma. Papel de las isoformas α y β del receptor glucocorticoideo

  2002cites this paper
• [Response to glucocorticoid treatment in asthma. The role of alpha and beta isoforms of the glucocorticoid receptor].

  2002cites this paper
• Intracellular Mechanisms of Antidepressant Drug Action

  2000cites this paper
• Cellular mechanisms in the vulnerability to depression and response to antidepressants.

  2000cites this paper
• Translational regulation of Na-K-ATPase subunit mRNAs by glucocorticoids.

  2000cites this paper
• Role of Endogenous Glucocorticoids in Immune System Function: Regulation and Counterregulation

  2000cites this paper
• Cortisol in teleosts: dynamics, mechanisms of action, and metabolic regulation

  1999cites this paper
• Transcription of the human thyrotropin-releasing hormone receptor gene-analysis of basal promoter elements and glucocorticoid response elements.

  1999cites this paper
• Glucocorticoid Receptor Isoforms Alpha and Beta: Potential Physiological and Pathological Importance

  1999cites this paper
• Glucocorticoid Receptor beta: View I.

  1999cites this paper
• Glucocorticoid Receptor β: View I

  1999cites this paper
• Control of hepatic insulin-like growth factor II gene expression by thyroid hormones in fetal sheep near term

  1998cites this paper
• A role for brain glucocorticoid receptors in contextual fear conditioning: dependence upon training intensity.

  1998cites this paper
• Control of hepatic insulin-like growth factor II gene expression by thyroid hormones in fetal sheep near term.

  1998cites this paper
• The Role and Mechanisms of Action of Glucocorticoid Involvement in Memory Storage

  1998cites this paper
• Glucocorticoids and the preparation for life after birth: are there long-term consequences of the life insurance?

  1998cites this paper
• Steroid pulse therapy for rheumatoid arthritis: effect on lymphocyte subsets and mononuclear cell adhesion.

  1998cites this paper
• A Mechanistic Basis for the Beneficial Effects of Caloric Restriction On Longevity and Disease: Consequences for the Interpretation of Rodent Toxicity Studies

  1998cites this paper
• Dexamethasone modulates the expression of endothelin-1 and -A receptors in A7r5 vascular smooth muscle cells.

  1998cites this paper
• The acute effect of lead acetate on glucocorticoid receptor binding in C6 glioma cells.

  1997cites this paper
• 17beta-estradiol stimulates substance P receptor gene expression.

  1997cites this paper
• Protein synthesis- and fucosylation-dependent mechanisms in corticosterone facilitation of long-term memory in the chick.

  1997cites this paper
• 17β-estradiol stimulates substance P receptor gene expression

  1997cites this paper
• Glucocorticoid effects on the skeletal muscle differentiation program: analysis of clonal proliferation, morphological differentiation and the expression of muscle-specific and regulatory genes.

  1997cites this paper
• Training-dependent biphasic effects of corticosterone in memory formation for a passive avoidance task in chicks

  1997cites this paper
• Lead may affect glucocorticoid signal transduction in cultured hepatoma cells through inhibition of protein kinase C.

  1997cites this paper
• HERPESVIRUS INFECTION IN STRANDED PACIFIC HARBOR SEALS OF COASTAL CALIFORNIA

  1997cites this paper
• Cyclosporin inhibits hyperalgesia and edema in arthritic rats: role of the central nervous system.

  1997cites this paper
• Regional and temporal modulation of brain glycoprotein synthesis by corticosterone.

  1996cites this paper
• New approaches to the treatment of depression.

  1996cites this paper
• The effect of (steroid) immunosuppression on skeletal muscle glycogen metabolism in patients after kidney transplantation.

  1996cites this paper
• Steroid receptor number. Individual variation and downregulation by treatment.

  1996cites this paper
• Androgen and glucocorticoid receptors in the stroma and epithelium of prostatic hyperplasia and carcinoma.

  1996cites this paper
• Cloning of glucocorticoid-regulated genes in C6/ST1 rat glioma phenotypic reversion.

  1996cites this paper
• Immunocytochemical and molecular analysis of the effects of glucocorticoid treatment on the hypothalamic-somatotropic axis in the rat.

  1996cites this paper
• [Glucocorticoid regulated gene in cells of the immune system. Mechanisms of immunomodulation].

  1996cites this paper
• Corticosterone facilitates long-term memory formation via enhanced glycoprotein synthesis.

  1995cites this paper
• A transition in transcriptional activation by the glucocorticoid and retinoic acid receptors at the tumor stage of dermal fibrosarcoma development.

  1995cites this paper
• Dexamethasone down-regulates the expression of endothelin B receptor mRNA in the rat brain.

  1995cites this paper
• Mechanisms of Action of Antidepressants

  1995cites this paper
• Biological markers of serotonin receptors in depression and animal models of depression

  1995cites this paper
• Effects of adrenalectomy and corticosterone replacement on glucocorticoid receptor levels in rat brain tissue: a comparison between western blotting and receptor binding assays.

  1995cites this paper
• Neuroendocrineimmunology (NEI) at the turn of the century: towards a molecular understanding of basic mechanisms and implications for reproductive physiopathology

  1995cites this paper
• Hormonal and cell density regulation of hepatic gamma-glutamylcysteine synthetase gene expression.

  1995cites this paper
• The acute effect of lead acetate on glucocorticoid regulation of tyrosine aminotransferase in hepatoma cells.

  1995cites this paper
• Dexamethasone-induced antagonism of growth hormone (GH) action by down-regulation of GH binding in 3T3-F442A fibroblasts.

  1995cites this paper
• Dexamethasone inhibits the production of macrophage inflammatory protein 2 in the leukocytes in rat allergic inflammation.

  1995cites this paper
• Effects of dexamethasone on protein degradation and protease gene expression in rat L8 myotube cultures.

  1995cites this paper
• Disruption of hypothalamic-pituitary-adrenocortical system in transgenic mice expressing type II glucocorticoid receptor antisense ribonucleic acid permanently impairs T cell function: effects on T cell trafficking and T cell responsiveness during postnatal development.

  1995cites this paper
• Glucocorticoid‐mediated immunomodulation: hydrocortisone enhances immunosuppressive endogenous retroviral protein (p15E) expression in mouse immune cells

  1995cites this paper
• Inhibition of interleukin-8 expression by dexamethasone in human cultured airway epithelial cells.

  1994cites this paper
• Tumor necrosis factor-induced interleukin-8 expression in cultured human airway epithelial cells.

  1994cites this paper
• Glucocorticoids negatively regulate the transcription of KC, the mouse homolog of MGSA/GRO.

  1994cites this paper
• Glucocorticoid‐induced changes in liver: Effect of dexamethasone administration on DNA topoisomerase I and II activities and distribution of histone H1 subtypes

  1994cites this paper
• Phosphorylation of immunopurified rat liver glucocorticoid receptor by the catalytic subunit of cAMP-dependent protein kinase

  1994cites this paper
• Regulation of sodium-calcium exchanger by glucocorticoids and growth factors in vascular smooth muscle.

  1994cites this paper
• Intragenic sequences of the human glucocorticoid receptor complementary DNA mediate hormone-inducible receptor messenger RNA down-regulation through multiple mechanisms.

  1994cites this paper
• Stress-induced changes in the affinity and abundance of cytosolic cortisol-binding sites in the liver of rainbow trout, Oncorhynchus mykiss (Walbaum), are not accompanied by changes in measurable nuclear binding

  1994cites this paper
• Glucocorticoids regulate somatostatin peptide and steady state messenger ribonucleic acid levels in normal rat tissues and in a somatostatin-producing islet tumor cell line (1027B2).

  1994cites this paper
• Glucocorticoid receptors and resistance to glucocorticoids in hematologic malignancies.

  1994cites this paper
• Dexamethasone inhibits IL-1 and TNF activity in human lung fibroblasts without affecting IL-1 or TNF receptors.

  1994cites this paper
• Corticosteroid Receptor Antagonists are Amnestic for Passive Avoidance Learning in Day‐old Chicks

  1994cites this paper
• The biological significance of glycyrrhizin- and glycyrrhetinic acid derivative-induced selective phosphorylation of histones H2A and H2B by A-kinase in vitro.

  1994cites this paper
• Inducible protein expression using a glucocorticoid-sensitive vector.

  1994cites this paper
• Glucocorticoid-induced formation of cross-linked actin networks in cultured human trabecular meshwork cells.

  1994cites this paper
• Transgenic Animals with Impaired Type II Glucocorticoid Receptor Gene Expression

  1994cites this paper
• Biphasic regulation of cytochrome P450 2B1/2 mRNA expression by dexamethasone in primary cultures of adult rat hepatocytes maintained on matrigel.

  1994cites this paper
• Regulation of apoptosis in S49 cells.

  1994cites this paper
• Corticosterone enhances long-term retention in one-day-old chicks trained in a weak passive avoidance learning paradigm.

  1994cites this paper
• Down regulation of CYP 1A1 by glucocorticoids in trout hepatocytes in vitro

  1993cites this paper
• Opioid Peptide Genes: Structure and Regulation

  1993cites this paper