A Null Mutation in the Gene Encoding the Herpes Simplex Virus Type 1 UL37 Polypeptide Abrogates Virus Maturation

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Journal of Virology

• Publication date

  2001-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/JVI.75.21.10259-10271.2001PMID 11581394PMCID PMC114600
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Herpes Simplex Virus Nucleocapsids Mature to Progeny Virions by an Envelopment → Deenvelopment → Reenvelopment Pathway

  2001cited by this paper
• Egress of Alphaherpesviruses: Comparative Ultrastructural Study

  2001cited by this paper
• A Null Mutation in the UL36 Gene of Herpes Simplex Virus Type 1 Results in Accumulation of Unenveloped DNA-Filled Capsids in the Cytoplasm of Infected Cells

  2000influential reference
• Herpes Simplex Virus Type 1 UL34 Gene Product Is Required for Viral Envelopment

  2000cited by this paper
• Evidence that Herpes Simplex Virus VP16 Is Required for Viral Egress Downstream of the Initial Envelopment Event

  2000influential reference
• Identification of nuclear export signal in UL37 protein of herpes simplex virus type 2.

  2000cited by this paper
• The Herpes Simplex Virus Type 1 UL17 Gene Encodes Virion Tegument Proteins That Are Required for Cleavage and Packaging of Viral DNA

  1998cited by this paper
• Incorporation of the Green Fluorescent Protein into the Herpes Simplex Virus Type 1 Capsid

  1998cited by this paper
• Infection and spread of alphaherpesviruses in the nervous system.

  1998cited by this paper
• Herpes simplex virus type 1 VP26 is not essential for replication in cell culture but influences production of infectious virus in the nervous system of infected mice.

  1998influential reference
• Capsids are formed in a mutant virus blocked at the maturation site of the UL26 and UL26.5 open reading frames of herpes simplex virus type 1 but are not formed in a null mutant of UL38 (VP19C).

  1998cited by this paper
• Structural biology of viruses

  1997cited by this paper
• Intercellular trafficking and protein delivery by a herpesvirus structural protein.

  1997cited by this paper
• The abundance of the herpes simplex virus type 1 UL37 tegument protein in virus particles is closely controlled.

  1997cited by this paper
• Overexpression of the herpes simplex virus type 1 tegument protein VP22 increases its incorporation into virus particles.

  1996cited by this paper
• The UL37 protein of herpes simplex virus type 1 is associated with the tegument of purified virions.

  1995cited by this paper
• The herpes simplex virus type 1 UL37 gene product is a component of virus particles.

  1994cited by this paper
• Retention of the herpes simplex virus type 1 (HSV-1) UL37 protein on single-stranded DNA columns requires the HSV-1 ICP8 protein

  1994cited by this paper
• The size and symmetry of B capsids of herpes simplex virus type 1 are determined by the gene products of the UL26 open reading frame

  1994influential reference
• Disruption of endoplasmic reticulum to Golgi transport leads to the accumulation of large aggregates containing beta-COP in pancreatic acinar cells.

  1993cited by this paper
• Herpes simplex virus type 1 UL46 and UL47 deletion mutants lack VP11 and VP12 or VP13 and VP14, respectively, and exhibit altered viral thymidine kinase expression

  1993cited by this paper
• The herpes simplex virus UL37 protein is phosphorylated in infected cells

  1993cited by this paper
• Mutations in herpes simplex virus type 1 genes encoding VP5 and VP23 abrogate capsid formation and cleavage of replicated DNA

  1993cited by this paper
• The UL13 virion protein of herpes simplex virus type 1 is phosphorylated by a novel virus-induced protein kinase.

  1992cited by this paper
• Deletion of the VP16 open reading frame of herpes simplex virus type 1

  1992influential reference
• Analysis of the UL36 open reading frame encoding the large tegument protein (ICP1/2) of herpes simplex virus type 1

  1992influential reference
• The UL11 gene of herpes simplex virus 1 encodes a function that facilitates nucleocapsid envelopment and egress from cells

  1992cited by this paper
• The herpes simplex virus 1 RNA binding protein US11 is a virion component and associates with ribosomal 60S subunits

  1992cited by this paper
• Identification of the genes encoding two capsid proteins of herpes simplex virus type 1 by direct amino acid sequencing.

  1990cited by this paper
• Identification and characterization of the herpes simplex virus type 1 protein encoded by the UL37 open reading frame

  1990cited by this paper
• Physical mapping and nucleotide sequence of a herpes simplex virus type 1 gene required for capsid assembly

  1989cited by this paper
• Herpes simplex virus virion host shutoff function

  1988cited by this paper
• The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1.

  1988cited by this paper
• Mutational analysis of the herpes simplex virus type 1 trans-inducing factor Vmw65.

  1988influential reference
• The herpes simplex virus virion host shutoff function

  1988cited by this paper
• Identification of the herpes simplex virus protein kinase as the product of viral gene US3.

  1987cited by this paper
• Characterization and nucleotide sequence of two herpes simplex virus 1 genes whose products modulate alpha-trans-inducing factor-dependent activation of alpha genes

  1987cited by this paper
• Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4

  1985cited by this paper
• Identification of herpes simplex virus DNA sequences which encode a trans-acting polypeptide responsible for stimulation of immediate early transcription.

  1984cited by this paper
• Molecular genetics of herpes simplex virus. VIII. further characterization of a temperature-sensitive mutant defective in release of viral DNA and in other stages of the viral reproductive cycle

  1983cited by this paper
• Herpes simplex virus mutants defective in the virion-associated shutoff of host polypeptide synthesis and exhibiting abnormal synthesis of alpha (immediate early) viral polypeptides

  1983cited by this paper
• Characterization of the herpes simplex virion-associated factor responsible for the induction of alpha genes

  1983cited by this paper
• Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

  1982cited by this paper
• Regulation of alpha genes of herpes simplex virus: expression of chimeric genes produced by fusion of thymidine kinase with alpha gene promoters.

  1981cited by this paper
• Regulation of α genes of herpes simplex virus: Expression of chimeric genes produced by fusion of thymidine kinase with α gene promoters

  1981cited by this paper
• Molecular Genetics of Herpes Simplex Virus VI. Characterization of a Temperature-Sensitive Mutant Defective in the Expression of All Early Viral Gene Products

  1981cited by this paper
• The Replication of Herpesviruses

  1974cited by this paper
• Electron Microscopy of Herpes Simplex Virus

  1968cited by this paper
• Electron Microscopy of Herpes Simplex Virus

  1968cited by this paper

• The loss of both pUL16 and pUL21 in HSV-1-infected cells alters capsid–tegument composition, nuclear membrane architecture, cytoplasmic maturation and cell-to-cell spread

  2025cites this paper
• The precise function of alphaherpesvirus tegument proteins and their interactions during the viral life cycle

  2024cites this paper
• Tracing the STING exocytosis pathway during herpes viruses infection

  2024cites this paper
• A Hitchhiker's Guide Through the Cell: The World According to the Capsids of Alphaherpesviruses.

  2024cites this paper
• The transmembrane and cytosolic domains of equine herpesvirus type 1 glycoprotein D determine Golgi retention by regulating vesicle formation.

  2024cites this paper
• The loss of both pUL16 and pUL21 in HSV-1 infected cells abolishes cytoplasmic envelopment

  2024cites this paper
• HSV Replication: Triggering and Repressing STING Functionality

  2023cites this paper
• Large Subunit of the Human Herpes Simplex Virus Terminase as a Promising Target in Design of Anti-Herpesvirus Agents

  2023cites this paper
• Inactivation of the UL37 Deamidase Enhances Virus Replication and Spread of the HSV-1(VC2) Oncolytic Vaccine Strain and Secretion of GM-CSF

  2023cites this paper
• Comparative full genome sequence analysis of wild-type and chicken embryo origin vaccine-like infectious Laryngotracheitis virus field isolates from Canada.

  2022cites this paper
• Pathogenesis and virulence of herpes simplex virus

  2021cites this paper
• Motor Skills: Recruitment of Kinesins, Myosins and Dynein during Assembly and Egress of Alphaherpesviruses

  2021cites this paper
• Tegument Assembly, Secondary Envelopment and Exocytosis.

  2021cites this paper
• Identification of Buffer Conditions for Optimal Thermostability and Solubility of Herpesviral Protein UL37 Using the Thermofluor Assay.

  2020cites this paper
• Nuclear Egress

  2020cites this paper
• HSV-1 Cytoplasmic Envelopment and Egress

  2020influential citation
• Nuclear Egress of Herpesviruses.

  2020cites this paper
• Microtubule-Dependent Trafficking of Alphaherpesviruses in the Nervous System: The Ins and Outs

  2019cites this paper
• The BOLF1 gene is necessary for effective Epstein-Barr viral infectivity.

  2019cites this paper
• Pathogenesis of ovine gamma herpesvirus 2 in rabbits involves productive infection of M-cells in the appendix

  2019influential citation
• Seeking Closure: How Do Herpesviruses Recruit the Cellular ESCRT Apparatus?

  2019cites this paper
• Functional Domains of the Herpes Simplex Virus Type 1 Tegument Protein pUL37: The Amino Terminus is Dispensable for Virus Replication in Tissue Culture

  2019cites this paper
• Investigating the structure and function of HSV-1 tegument proteins, UL7 and UL51

  2018cites this paper
• The dynamic nature of the conserved tegument protein UL37 of herpesviruses

  2018cites this paper
• Consensus clustering of herpesvirus protein interaction networks provides insights into their evolutionary relationship with bacteriophages

  2018cites this paper
• Data-Driven Computational Approach to Study Bio-Molecular Interactions

  2018cites this paper
• Infection and Transport of Herpes Simplex Virus Type 1 in Neurons: Role of the Cytoskeleton

  2018cites this paper
• L’étude de la glycoprotéine gM du virus Herpès simplex de type 1 (HSV-l) : identification de ses partenaires viraux et cellulaires et leur rôle dans la régulation de l’infection virale

  2018cites this paper
• The pUL37 tegument protein guides alpha-herpesvirus retrograde axonal transport to promote neuroinvasion

  2017cites this paper
• Crystal Structure of the N-Terminal Half of the Traffic Controller UL37 from Herpes Simplex Virus 1

  2017cites this paper
• ESCDL-1, a new cell line derived from chicken embryonic stem cells, supports efficient replication of Mardiviruses

  2017cites this paper
• Inner tegument proteins of Herpes Simplex Virus are sufficient for intracellular capsid motility in neurons but not for axonal targeting

  2017cites this paper
• Novel Structure and Unexpected RNA-Binding Ability of the C-Terminal Domain of Herpes Simplex Virus 1 Tegument Protein UL21

  2016cites this paper
• Nuclear Exodus: Herpesviruses Lead the Way.

  2016cites this paper
• Herpes Simplex Virus 1 UL37 Protein Tyrosine Residues Conserved among All Alphaherpesviruses Are Required for Interactions with Glycoprotein K, Cytoplasmic Virion Envelopment, and Infectious Virus Production

  2016cites this paper
• A Viral Deamidase Targets the Helicase Domain of RIG-I to Block RNA-Induced Activation.

  2016cites this paper
• The Interaction between Herpes Simplex Virus 1 Tegument Proteins UL51 and UL14 and Its Role in Virion Morphogenesis

  2016influential citation
• A Viral Deamidase Targets the Helicase Domain of RIGI to Block RNA-Induced Activation Graphical

  2016cites this paper
• Insights into the function of tegument proteins from the varicella zoster virus

  2015cites this paper
• Tegument Assembly and Secondary Envelopment of Alphaherpesviruses

  2015cites this paper
• Identification of non-essential loci within the Meleagrid herpesvirus 1 genome

  2015cites this paper
• Herpes Simplex Virus Capsid-Organelle Association in the Absence of the Large Tegument Protein UL 36 p

  2015cites this paper
• Function and transport of a herpesvirus encoded ubiquitin-specific protease in virus entry and assembly

  2015influential citation
• Human Cytomegalovirus pUL47 Modulates Tegumentation and Capsid Accumulation at the Viral Assembly Complex

  2015cites this paper
• Conserved tegument protein complexes: Essential components in the assembly of herpesviruses.

  2015cites this paper
• Simian varicella virus and varicella-zoster virus immune evasion of NFkB activation

  2015cites this paper
• Herpes Simplex Virus Capsid-Organelle Association in the Absence of the Large Tegument Protein UL36p

  2015cites this paper
• Deletion of Murid Herpesvirus 4 ORF63 Affects the Trafficking of Incoming Capsids toward the Nucleus

  2015influential citation
• Cellular Protein WDR11 Interacts with Specific Herpes Simplex Virus Proteins at the trans-Golgi Network To Promote Virus Replication

  2015cites this paper
• Phenylalanine Residues at the Carboxyl Terminus of the Herpes Simplex Virus 1 UL20 Membrane Protein Regulate Cytoplasmic Virion Envelopment and Infectious Virus Production

  2014cites this paper
• Varicella-zoster virus induces the formation of dynamic nuclear capsid aggregates.

  2014cites this paper
• Herpes Simplex Virus 1 Protein UL37 Interacts with Viral Glycoprotein gK and Membrane Protein UL20 and Functions in Cytoplasmic Virion Envelopment

  2014cites this paper
• Crystal Structure of the Herpesvirus Inner Tegument Protein UL37 Supports Its Essential Role in Control of Viral Trafficking

  2014influential citation
• The Large Tegument Protein pUL36 Is Essential for Formation of the Capsid Vertex-Specific Component at the Capsid-Tegument Interface of Herpes Simplex Virus 1

  2014cites this paper
• The interaction of the HSV-1 tegument proteins pUL36 and pUL37 is essential for secondary envelopment during viral egress.

  2014cites this paper
• Nelfinavir Inhibits Maturation and Export of Herpes Simplex Virus 1

  2014cites this paper
• The interaction of HSV-1 tegument proteins pUL36 and pUL37: a novel target for antivirals that inhibit viral assembly

  2014cites this paper
• Genetics and Functions of Herpes Simplex Virus Type-1 Membrane Proteins UL20/gK in Virion Envelopment and Entry

  2014cites this paper
• UL20 Membrane Protein Regulate Cytoplasmic Virion Envelopment and Infectious Virus

  2014cites this paper
• The Role of HSV-2 Proteins ICP0 and Us3 in Counteracting Cellular Antiviral Defence

  2014cites this paper
• Investigation of the activation of innate antiviral signaling and its counteraction by the herpes simplex virus protein ICP0

  2014cites this paper
• Analysis of the Early Steps of Herpes Simplex Virus 1 Capsid

  2013cites this paper
• The UL36-encoded ubiquitin-specific protease in Marek's disease virus replication and tumourigenesis

  2013cites this paper
• Dystonin/BPAG1 Promotes Plus-End-Directed Transport of Herpes Simplex Virus 1 Capsids on Microtubules during Entry

  2013cites this paper
• Cytosolic herpes simplex virus capsids not only require binding inner tegument protein pUL36 but also pUL37 for active transport prior to secondary envelopment

  2013influential citation
• Characterization of the Alphaherpesvirus Tegument Protein US2

  2013cites this paper
• Analysis of the Early Steps of Herpes Simplex Virus 1 Capsid Tegumentation

  2013cites this paper
• Possible TAP inhibitors in HHV-6 and HHV-7 based on known characteristics of TAP inhibitors and their evolutionary development in herpesviruses.

  2013cites this paper
• Identification of cellular factors involved in herpes simplex virus type 1 nuclear egress

  2012cites this paper
• Loss of Cytoskeletal Transport during Egress Critically Attenuates Ectromelia Virus Infection In Vivo

  2012cites this paper
• Identification of a single amino acid residue which is critical for the interaction between HSV-1 inner tegument proteins pUL36 and pUL37.

  2012cites this paper
• Herpesvirus Tegument Protein pUL37 Interacts with Dystonin/BPAG1 To Promote Capsid Transport on Microtubules during Egress

  2012cites this paper
• Identification of host cell proteins which interact with herpes simplex virus type 1 tegument protein pUL37.

  2012cites this paper
• Caractérisation de la migration du virus Herpès simplex de type 1 (HSV-1) par protéomique

  2012cites this paper
• Role of Herpes Simplex Type I Glycoproteins in Entry and Cell-cell Fusion

  2012cites this paper
• Identification of interaction domains within the UL37 tegument protein of herpes simplex virus type 1.

  2011cites this paper
• Identification and characterization of low pH-triggered conformational changes in the herpes simplex virus glycoprotein B

  2011cites this paper
• Herpes Simplex Virus Requires VP11/12 To Activate Src Family Kinase-Phosphoinositide 3-Kinase-Akt Signaling

  2011cites this paper
• Herpes Simplex Virus Type 1: Secretion, Cell Signaling, And Gene Expression

  2011cites this paper
• Alphaherpesviruses and the Cytoskeleton in Neuronal Infections

  2011cites this paper
• PROTEASOME-DEPENDENT ENTRY OF HERPES SIMPLEX VIRUS

  2010cites this paper
• Random Transposon-Mediated Mutagenesis of the Essential Large Tegument Protein pUL36 of Pseudorabies Virus

  2010influential citation
• Complex mechanisms for the packaging of the UL16 tegument protein into herpes simplex virus.

  2010cites this paper
• Role of tegument proteins in herpesvirus assembly and egress

  2010cites this paper
• Inner tegument protein pUL37 of herpes simplex virus type 1 is involved in directing capsids to the trans-Golgi network for envelopment

  2010cites this paper
• On the rules of co-existence between sheep, cattle, and OvHV-2

  2010cites this paper
• Plus- and Minus-End Directed Microtubule Motors Bind Simultaneously to Herpes Simplex Virus Capsids Using Different Inner Tegument Structures

  2010cites this paper
• Herpesvirus assembly: an update.

  2009cites this paper
• Functional roles of the tegument proteins of herpes simplex virus type 1.

  2009cites this paper
• Intracellular Localization of the Pseudorabies Virus Large Tegument Protein pUL36

  2009influential citation
• Interactions between ICP4 and the cellular transcription machinery that mediate HSV-1 gene expression

  2009cites this paper
• Host And Viral Factors Involved In Regulation Of Nuclear Egress Of Herpes Simplex Virus

  2009cites this paper
• Translocation of Incoming Pseudorabies Virus Capsids to the Cell Nucleus Is Delayed in the Absence of Tegument Protein pUL37

  2009influential citation
• Phenotypic similarities and differences between UL37-deleted pseudorabies virus and herpes simplex virus type 1.

  2009influential citation
• The Major Determinant for Addition of Tegument Protein pUL48 (VP16) to Capsids in Herpes Simplex Virus Type 1 Is the Presence of the Major Tegument Protein pUL36 (VP1/2)

  2009cites this paper
• Antiviral chemotherapeutic agents against equine herpesvirus type 1: the mechanism of antiviral effects of porphyrin derivatives

  2009cites this paper
• Virion Incorporation of the Herpes Simplex Virus Type 1 Tegument Protein VP22 Occurs via Glycoprotein E-Specific Recruitment to the Late Secretory Pathway

  2009cites this paper
• Characterization of the herpes simplex virus (HSV)-1 tegument protein VP1-2 during infection with the HSV temperature-sensitive mutant tsB7.

  2009influential citation
• Ovine herpesvirus 2 structural proteins in epithelial cells and M-cells of the appendix in rabbits with malignant catarrhal fever.

  2009cites this paper
• Localization of Herpes Simplex Virus Type 1 UL37 in the Golgi Complex Requires UL36 but Not Capsid Structures

  2008cites this paper