Involvement of cystatin C in immunity and apoptosis

Meng Zi,Yuekang Xu

Published 2018 in Immunology Letters

ABSTRACT

Highlights • Cystatin C is not only a good index of kidney functions but also involved in immune regulation and apoptosis under pathological conditions.• The involvement of cystatin C in the immunological process occurs at multiple levels, which are subjected to cytokine regulation.• Abnormal cystatin C expression is associated with inflammatory autoimmune diseases and tumor development.• Thus cystatin C can be a valid therapeutic target for these diseases.

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