Mechanisms of monoclonal antibody stabilization and release from silk biomaterials.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Biomaterials

• Publication date

  2013-10-01

• Fields of study

  Medicine, Materials Science

• Identifiers
  DOI 10.1016/j.biomaterials.2013.06.039PMID 23859659PMCID PMC3756937
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release.

  2012cited by this paper
• Stabilization of vaccines and antibiotics in silk and eliminating the cold chain

  2012cited by this paper
• Fabrication of Silk Microneedles for Controlled‐Release Drug Delivery

  2012cited by this paper
• Antibody-drug conjugates: basic concepts, examples and future perspectives.

  2012cited by this paper
• Design and Characterization of a Silk-Fibroin-Based Drug Delivery Platform Using Naproxen as a Model Drug

  2012cited by this paper
• Studies of in situ-forming hydrogels by blending PLA-PEG-PLA copolymer with silk fibroin solution.

  2012cited by this paper
• Trial Watch: Monoclonal antibodies in cancer therapy

  2012cited by this paper
• Recombinant spider silk particles for controlled delivery of protein drugs.

  2012cited by this paper
• Forced degradation of therapeutic proteins.

  2012cited by this paper
• Lyophilized silk fibroin hydrogels for the sustained local delivery of therapeutic monoclonal antibodies.

  2011cited by this paper
• Preparation, characterization and biocompatibility of electrospinning heparin-modified silk fibroin nanofibers.

  2011cited by this paper
• Mechanisms of controlled release from silk fibroin films.

  2011cited by this paper
• Materials fabrication from Bombyx mori silk fibroin

  2011cited by this paper
• Effects of surfaces and leachables on the stability of biopharmaceuticals.

  2011cited by this paper
• Regulation of silk material structure by temperature-controlled water vapor annealing.

  2011cited by this paper
• Stability of Protein Pharmaceuticals: An Update

  2010cited by this paper
• Effect of hydration on silk film material properties.

  2010cited by this paper
• Silk fibroin encapsulated powder reservoirs for sustained release of adenosine.

  2010cited by this paper
• Development trends for human monoclonal antibody therapeutics

  2010cited by this paper
• Water-insoluble silk films with silk I structure.

  2010cited by this paper
• Biomaterials from ultrasonication-induced silk fibroin-hyaluronic acid hydrogels.

  2010cited by this paper
• Stabilization and release of enzymes from silk films.

  2010cited by this paper
• Insoluble and flexible silk films containing glycerol.

  2010cited by this paper
• Mechanisms of protein stabilization in the solid state.

  2009cited by this paper
• Surface modification of silk fibroin with poly(ethylene glycol) for antiadhesion and antithrombotic applications.

  2009cited by this paper
• Stabilization of enzymes in silk films.

  2009cited by this paper
• Protein aggregation: pathways, induction factors and analysis.

  2009cited by this paper
• Therapeutic antibodies coming through the pipeline.

  2008cited by this paper
• In vivo degradation of three-dimensional silk fibroin scaffolds.

  2008cited by this paper
• Nanolayer biomaterial coatings of silk fibroin for controlled release.

  2007cited by this paper
• Effect of water on the thermal properties of silk fibroin

  2007cited by this paper
• Reactive oxygen species and DNA damage after ultrasound exposure.

  2007cited by this paper
• Development of an in vitro potency assay for therapeutic TGFbeta antagonists: the A549 cell bioassay.

  2006cited by this paper
• Development of an in vitro potency bioassay for therapeutic IL-13 antagonists: The A-549 cell bioassay

  2006cited by this paper
• Characterization of the stability of a fully human monoclonal IgG after prolonged incubation at elevated temperature.

  2006cited by this paper
• In vitro degradation of silk fibroin.

  2005cited by this paper
• Phase behavior and hydration of silk fibroin.

  2004cited by this paper
• Biodegradable microspheres for protein delivery.

  2003cited by this paper
• Macrophage responses to silk.

  2003cited by this paper
• Stabilization of proteins encapsulated in injectable poly (lactide-co-glycolide)

  2000cited by this paper
• Polymeric systems for controlled drug release.

  1999cited by this paper
• Drug delivery and targeting.

  1998cited by this paper
• Advanced and controlled drug delivery systems in clinical disease management

  1996cited by this paper
• Infrared spectroscopic studies of lyophilization- and temperature-induced protein aggregation.

  1995cited by this paper
• Protein secondary structures in water from second-derivative amide I infrared spectra.

  1990cited by this paper
• INVITED REVIEW POLYMERIC DELIVERY SYSTEMS FOR CONTROLLED DRUG RELEASE

  1980cited by this paper

• Bioinspired silk protein modification to develop instant dissolvable microneedles with superior mechanical properties and long-term biomolecule stabilization.

  2025cites this paper
• Biomimetic peptide conjugates as emerging strategies for controlled release from protein-based materials

  2025cites this paper
• Formulation and characterization of ionically crosslinked gellan gum hydrogels using trilysine at low temperatures for antibody delivery.

  2024cites this paper
• Permselectivity of Silk Fibroin Hydrogels for Advanced Drug Delivery Neurotherapies

  2024cites this paper
• Engineering seed microenvironment with embedded bacteriophages and plant growth promoting rhizobacteria

  2024cites this paper
• Advances of regenerated and functionalized silk biomaterials and application in skin wound healing.

  2023cites this paper
• Cooperative assembly of a designer peptide and silk fibroin into hybrid nanofiber gels for neural regeneration after spinal cord injury

  2023cites this paper
• Silk Fibroin as an Efficient Biomaterial for Drug Delivery, Gene Therapy, and Wound Healing

  2022cites this paper
• Silk Hydrogel-Mediated Delivery of Bone Morphogenetic Protein 7 Directly to Subcutaneous White Adipose Tissue Increases Browning and Energy Expenditure

  2022cites this paper
• Study on a Natural Silk Cocoon Membrane-Based Versatile and Stable Immunosensing Platform via Directional Immunoaffinity Recognition

  2022cites this paper
• Classification, material types, and design approaches of long-acting and implantable drug delivery systems

  2022cites this paper
• Long-Term Preservation of SARS-CoV-2 RNA in Silk for Downstream RT-PCR Tests

  2022cites this paper
• Promising Role of Silk-Based Biomaterials for Ocular-Based Drug Delivery and Tissue Engineering

  2022cites this paper
• Reshaping de Novo Protein Switches into Bioresponsive Materials for Biomarker, Toxin, and Viral Detection

  2022cites this paper
• Stabilizing Enzymes in Plasmonic Silk Film for Synergistic Therapy of In Situ SERS Identified Bacteria

  2022cites this paper
• Challenges in delivering therapeutic peptides and proteins: A silk-based solution.

  2022cites this paper
• Sustained Release Systems for Delivery of Therapeutic Peptide/Protein.

  2021cites this paper
• Long-acting silk fibroin xerogel delivery systems for controlled release of estradiol

  2021cites this paper
• Preparation of Silk Fibroin/Carboxymethyl Chitosan Hydrogel under Low Voltage as a Wound Dressing

  2021cites this paper
• Silk fibroin double-layer microneedles for the encapsulation and controlled release of triptorelin.

  2021cites this paper
• Creation of stable water-free antibody based protein liquids

  2021cites this paper
• (Macro)molecular self-assembly for hydrogel drug delivery.

  2021cites this paper
• Antibacterial application of gentamicin-silk protein coating with smart release function on titanium, polyethylene, and Al2O3 materials.

  2021cites this paper
• Spectroscopic analysis of Muga silk nanoparticles synthesized by microwave method

  2020cites this paper
• Silk fibroin as a natural polymeric based bio-material for tissue engineering and drug delivery systems-A review.

  2020cites this paper
• Thin silk fibroin films as a dried format for temperature stabilization of inactivated polio vaccine.

  2020cites this paper
• Natural Materials and Products from Insects: Chemistry and Applications

  2020cites this paper
• Silk Fibroin Microneedle Patches for the Sustained Release of Levonorgestrel

  2020cites this paper
• Silk: An Amazing Biomaterial for Future Medication

  2020cites this paper
• Fabrication of 3D Scaffolds Displaying Biochemical Gradients along Longitudinally Oriented Microchannels for Neural Tissue Engineering.

  2020cites this paper
• Chapter 3: Enabling Biologics Combination Products: Device Ability in Protein Therapeutics

  2020cites this paper
• Development of a Dinutuximab Delivery System Using Silk Foams for GD2 Targeted Neuroblastoma Cell Death.

  2020cites this paper
• Insight into Silk-Based Biomaterials: From Physicochemical Attributes to Recent Biomedical Applications.

  2019cites this paper
• Silk materials for medical, electronic and optical applications

  2019cites this paper
• Sustained release silk fibroin discs: Antibody and protein delivery for HIV prevention

  2019cites this paper
• Controlled-release neurotensin-loaded silk fibroin dressings improve wound healing in diabetic rat model

  2019cites this paper
• Silk materials for medical, electronic and optical applications

  2019cites this paper
• Control of octreotide release from silk fibroin microspheres.

  2019cites this paper
• Extended release formulations using silk proteins for controlled delivery of therapeutics

  2019influential citation
• Preparation of regenerated silk fibroin‐based heat‐management sponge for wound healing

  2019cites this paper
• Phosphorylation of Silk Fibroin via Maillard Reaction and Its Behavior of Biomimetic Mineralization

  2019cites this paper
• Silk Fibroin as a Functional Biomaterial for Drug and Gene Delivery

  2019cites this paper
• Thermoplastic Molding of Regenerated Silk

  2019cites this paper
• Water-Based Black Phosphorus Hybrid Nanosheets as a Moldable Platform for Wound Healing Applications.

  2018cites this paper
• Thermal Stabilization of Biologics with Photoresponsive Hydrogels.

  2018cites this paper
• Implantable Polymeric Drug Delivery Devices: Classification, Manufacture, Materials, and Clinical Applications

  2018cites this paper
• A Review of the Emerging Role of Silk for the Treatment of the Eye

  2018cites this paper
• Novel silk fibroin nanoparticles incorporated silk fibroin hydrogel for inhibition of cancer stem cells and tumor growth

  2018cites this paper
• Combinatorial Therapies After Spinal Cord Injury: How Can Biomaterials Help?

  2017cites this paper
• DNA preservation in silk.

  2017cites this paper
• Enhanced Stabilization in Dried Silk Fibroin Matrices.

  2017cites this paper
• 2.12 Silk Biomaterials

  2017cites this paper
• Stabilization and Sustained Release of HIV Inhibitors by Encapsulation in Silk Fibroin Disks.

  2017cites this paper
• 3D Printing of Regenerated Silk Fibroin and Antibody-Containing Microstructures via Multiphoton Lithography.

  2017cites this paper
• Combinatorial drug delivery approaches for immunomodulation

  2017cites this paper
• Silk-based blood stabilization for diagnostics

  2016cites this paper
• Development of antibiotic-loaded silk fibroin/hyaluronic acid polyelectrolyte film coated CoCrMo alloy

  2016cites this paper
• [Application of silk-based tissue engineering scaffold for tendon / ligament regeneration].

  2016cites this paper
• Silk fibroin sponges with cell growth-promoting activity induced by genetically fused basic fibroblast growth factor.

  2016cites this paper
• Optimizing Molecular Weight of Lyophilized Silk As a Shelf-Stable Source Material.

  2016cites this paper
• The Use of Silk in Nanomedicine Applications

  2016cites this paper
• Direct Formation of Silk Nanoparticles for Drug Delivery.

  2016cites this paper
• Silk hydrogels for sustained ocular delivery of anti-vascular endothelial growth factor (anti-VEGF) therapeutics.

  2015cites this paper
• Gutachter

  2015influential citation
• Silk-based stabilization of biomacromolecules.

  2015cites this paper
• Silk as an innovative biomaterial for cancer therapy.

  2015cites this paper
• In Vitro Controlled Release of Topically Applied Capsaicin from Silk Hydrogel: A Study Contributed to the Pain Relief System

  2015cites this paper
• On the Routines of Wild-Type Silk Fibroin Processing Toward Silk-Inspired Materials: A Review

  2015cites this paper
• Développement d’une protéine à libération prolongée, mise au point du procédé d’encapsulation sans solvant halogéné et optimisation du profil de libération.

  2015cites this paper
• Silk fibroin nanoparticle as a novel drug delivery system.

  2015cites this paper
• Modulation of vincristine and doxorubicin binding and release from silk films.

  2015cites this paper
• Modulated Degradation of Transient Electronic Devices through Multilayer Silk Fibroin Pockets.

  2015cites this paper
• Characteristics of platelet gels combined with silk.

  2014cites this paper
• Nanoscale Control of Silks for Nanofibrous Scaffold Formation with Improved Porous Structure.

  2014cites this paper
• Therapeutic efficacy of antibiotic-loaded gelatin microsphere/silk fibroin scaffolds in infected full-thickness burns.

  2014cites this paper
• Deciphering the mechanism of protein interaction with silk fibroin for drug delivery systems.

  2014cites this paper
• Silk-based biomaterials for sustained drug delivery.

  2014cites this paper