Sustained hemodynamic effects of an infusion of nesiritide (human b-type natriuretic peptide) in heart failure: a randomized, double-blind, placebo-controlled clinical trial. Natrecor Study Group.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Journal of the American College of Cardiology

• Publication date

  1999-07-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/S0735-1097(99)00184-9PMID 10400005
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1997cited by this paper
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  1995cited by this paper
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  1994cited by this paper
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  1993cited by this paper
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  1992cited by this paper
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  1991cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1987cited by this paper
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  1986cited by this paper
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  1984cited by this paper

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