Pressure overload induces IL-18 and IL-18R expression, but markedly suppresses IL-18BP expression in a rabbit model. IL-18 potentiates TNF-α-induced cardiomyocyte death.

Tadashi Yoshida,I. Friehs,S. Mummidi,P. D. del Nido,Solange Addulnour-Nakhoul,P. Delafontaine,A. Valente,B. Chandrasekar

Published 2014 in Journal of Molecular and Cellular Cardiology

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