The impact of FANCD 2 deficiency on formaldehyde-induced toxicity in human lymphoblastoid cell lines

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Not labeled

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• A common environmental carcinogen unduly affects carriers of cancer mutations: carriers of genetic mutations in a specific protective response are more susceptible to an environmental carcinogen.

  2011cited by this paper
• Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway

  2011influential reference
• Micronuclei frequency in peripheral blood lymphocytes and cancer risk: evidence from human studies.

  2011cited by this paper
• Repair pathways independent of the Fanconi anemia nuclear core complex play a predominant role in mitigating formaldehyde-induced DNA damage.

  2011influential reference
• Genomic instability in mice is greater in Fanconi anemia caused by deficiency of Fancd2 than Fancg.

  2010cited by this paper
• Formaldehyde-induced chromosomal aberrations and apoptosis in peripheral blood lymphocytes of personnel working in pathology departments.

  2010cited by this paper
• Hematopoietic Stem Cell Defects in Mice with Deficiency of Fancd2 or Usp1

  2010cited by this paper
• Relationship between DNA lesions, DNA repair and chromosomal damage induced by acetaldehyde.

  2009cited by this paper
• A review of human carcinogens--Part F: chemical agents and related occupations.

  2009cited by this paper
• Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights.

  2009cited by this paper
• Homologous Recombination but Not Nucleotide Excision Repair Plays a Pivotal Role in Tolerance of DNA-Protein Cross-links in Mammalian Cells*

  2009cited by this paper
• Cellular pathways for DNA repair and damage tolerance of formaldehyde-induced DNA-protein crosslinks.

  2009cited by this paper
• Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde.

  2007influential reference
• Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice.

  2003cited by this paper
• The Fanconi anaemia/BRCA pathway

  2003cited by this paper
• Positional cloning of a novel Fanconi anemia gene, FANCD2.

  2001influential reference
• Induction and repair of formaldehyde-induced DNA-protein crosslinks in repair-deficient human cell lines.

  2000cited by this paper
• The in vitro micronucleus technique.

  2000influential reference
• Significance of formaldehyde‐induced DNA–protein crosslinks for mutagenesis

  1998cited by this paper
• Interlaboratory validation of a new assay for DNA-protein crosslinks.

  1996cited by this paper
• A simple, sensitive assay to detect DNA-protein crosslinks in intact cells and in vivo.

  1992cited by this paper
• Cytogenetic effects in lymphocytes of formaldehyde workers of a paper factory.

  1985cited by this paper
• Formaldehyde (CH2O) concentrations in the blood of humans and Fischer-344 rats exposed to CH2O under controlled conditions.

  1985cited by this paper
• Repair of DNA damage caused by formaldehyde in human cells.

  1984cited by this paper
• Chromosome aberrations and sister-chromatid exchange frequencies in pathology staff occupationally exposed to formaldehyde.

  1984cited by this paper
• Environmental and Molecular Mutagenesis 51:181^191 (2010) Review Article Formaldehyde and Leukemia: Epidemiology, Potential Mechanisms, and Implications for Risk Assessment

  year unknowncited by this paper

• Functional Toxicogenomic Profiling Expands Insight into Modulators of Formaldehyde Toxicity in Yeast

  2016cites this paper
• Formaldehyde-induced histone H3 phosphorylation via JNK and the expression of proto-oncogenes.

  2014cites this paper