Equine infectious anemia virus trans-regulatory protein Rev controls viral mRNA stability, accumulation, and alternative splicing

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Journal of Virology

• Publication date

  1994-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/jvi.68.5.3102-3111.1994PMID 8151775PMCID PMC236800
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Posttranscriptional effector domains in the Rev proteins of feline immunodeficiency virus and equine infectious anemia virus

  1994cited by this paper
• Mutation of an RSV intronic element abolishes both U11/U12 snRNP binding and negative regulation of splicing.

  1993cited by this paper
• Rev and the fate of pre-mRNA in the nucleus: implications for the regulation of RNA processing in eukaryotes

  1993influential reference
• Structural and functional characterization of rev-like transcripts of equine infectious anemia virus

  1993influential reference
• Protein interactions with DNA elements in variant equine infectious anemia virus enhancers and their impact on transcriptional activity

  1993cited by this paper
• Translation of equine infectious anemia virus bicistronic tat-rev mRNA requires leaky ribosome scanning of the tat CTG initiation codon

  1993cited by this paper
• Analysis of multiple mRNAs from pathogenic equine infectious anemia virus (EIAV) in an acutely infected horse reveals a novel protein, Ttm, derived from the carboxy terminus of the EIAV transmembrane protein

  1993cited by this paper
• Intronic sequences and 3' splice sites control Rous sarcoma virus RNA splicing

  1992cited by this paper
• Wild-type equine infectious anemia virus replicates in vivo predominantly in tissue macrophages, not in peripheral blood monocytes

  1992cited by this paper
• Mechanism of action of regulatory proteins encoded by complex retroviruses

  1992cited by this paper
• Structural and functional analysis of the visna virus Rev-response element

  1992cited by this paper
• Identification of the Rev transactivation and Rev-responsive elements of feline immunodeficiency virus

  1992cited by this paper
• The role of branchpoint and 3'-exon sequences in the control of balanced splicing of avian retrovirus RNA.

  1991cited by this paper
• Mutational analysis of functional domains in the HIV-1 Rev trans-regulatory protein.

  1991cited by this paper
• Mutations in the regions of the Rous sarcoma virus 3' splice sites: implications for regulation of alternative splicing

  1991cited by this paper
• The Tat protein of equine infectious anemia virus is encoded by at least three types of transcripts.

  1991cited by this paper
• Identification of a hypervariable region in the long terminal repeat of equine infectious anemia virus

  1991cited by this paper
• Effector domains of human immunodeficiency virus type 1 Rev and human T-cell leukemia virus type I Rex are functionally interchangeable and share an essential peptide motif

  1991cited by this paper
• Oligomerization and RNA binding domains of the type 1 human immunodeficiency virus Rev protein: a dual function for an arginine-rich binding motif.

  1991cited by this paper
• HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: implications for HIV-1 latency.

  1991cited by this paper
• Characterization of Rous sarcoma virus intronic sequences that negatively regulate splicing.

  1991cited by this paper
• Identification of posttranscriptionally active inhibitory sequences in human immunodeficiency virus type 1 RNA: novel level of gene regulation

  1991cited by this paper
• Mechanisms of alternative pre-mRNA splicing.

  1991cited by this paper
• Mutational definition of the human immunodeficiency virus type 1 Rev activation domain

  1991cited by this paper
• Equine infectious anemia virus tat: insights into the structure, function, and evolution of lentivirus trans-activator proteins

  1990cited by this paper
• Cloning and functional analysis of multiply spliced mRNA species of human immunodeficiency virus type 1

  1990cited by this paper
• Proviral DNA integration and transcriptional patterns of equine infectious anemia virus during persistent and cytopathic infections

  1990cited by this paper
• Identification of sequences important in the nucleolar localization of human immunodeficiency virus Rev: relevance of nucleolar localization to function

  1990cited by this paper
• Secondary structure of the human T-cell leukemia virus type 1 rex-responsive element is essential for rex regulation of RNA processing and transport of unspliced RNAs

  1990cited by this paper
• Control of retroviral RNA splicing through maintenance of suboptimal processing signals

  1990cited by this paper
• Cloning and characterization of cDNAs encoding equine infectious anemia virus tat and putative Rev proteins

  1990cited by this paper
• Env and Vpu proteins of human immunodeficiency virus type 1 are produced from multiple bicistronic mRNAs

  1990cited by this paper
• Studies on the regulation and pattern of expression of the equine infectious anemia virus genome.

  1990cited by this paper
• Mutants in a conserved region near the carboxy-terminus of HIV-1 Rev identify functionally important residues and exhibit a dominant negative phenotype.

  1990cited by this paper
• HIV-1 regulator of virion expression (Rev) protein binds to an RNA stem-loop structure located within the Rev response element region.

  1990cited by this paper
• U1 small nuclear RNA plays a direct role in the formation of a rev-regulated human immunodeficiency virus env mRNA that remains unspliced.

  1990cited by this paper
• Mutational analysis of the human immunodeficiency virus type 1 Rev transactivator: essential residues near the amino terminus

  1990cited by this paper
• Interaction of the human immunodeficiency virus type 1 Rev protein with a structured region in env mRNA is dependent on multimer formation mediated through a basic stretch of amino acids.

  1990cited by this paper
• Identification of trans-dominant HIV-1 rev protein mutants by direct transfer of bacterially produced proteins into human cells.

  1990cited by this paper
• Regulated splicing of the Drosophila P transposable element third intron in vitro: somatic repression.

  1990cited by this paper
• Trans-activating rev protein of the human immunodeficiency virus 1 interacts directly and specifically with its target RNA.

  1990cited by this paper
• Sequence-specific RNA binding by the HIV-1 Rev protein

  1989cited by this paper
• Analysis of rev gene function on human immunodeficiency virus type 1 replication in lymphoid cells by using a quantitative polymerase chain reaction method

  1989cited by this paper
• Analysis of the cis-acting requirements for germ-line-specific splicing of the P-element ORF2-ORF3 intron.

  1989cited by this paper
• Cross-activation of the Rex proteins of HTLV-I and BLV and of the Rev protein of HIV-1 and nonreciprocal interactions with their RNA responsive elements.

  1989cited by this paper
• Regulation of human immunodeficiency virus env expression by the rev gene product

  1989cited by this paper
• Functional dissection of the HIV-1 Rev trans-activator--derivation of a trans-dominant repressor of Rev function.

  1989cited by this paper
• Regulation by HIV Rev depends upon recognition of splice sites.

  1989cited by this paper
• The rev gene product of the human immunodeficiency virus affects envelope-specific RNA localization.

  1989influential reference
• HTLV-I p27rex regulates gag and env protein expression.

  1989cited by this paper
• The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

  1989influential reference
• Viral DNA in horses infected with equine infectious anemia virus

  1989cited by this paper
• Specific binding of HIV-1 recombinant Rev protein to the Rev-responsive element in vitro

  1989cited by this paper
• Functional similarity of HIV-I rev and HTLV-I rex proteins: identification of a new nucleolar-targeting signal in rev protein.

  1989cited by this paper
• rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA.

  1989cited by this paper
• The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region

  1989influential reference
• The lentiviruses: maedi/visna, caprine arthritis-encephalitis, and equine infectious anemia.

  1988cited by this paper
• Subcellular localization of the human immunodeficiency virus trans-acting art gene product

  1988cited by this paper
• Intragenic cis-acting art gene-responsive sequences of the human immunodeficiency virus.

  1988influential reference
• cis- and trans-acting regulation of gene expression of equine infectious anemia virus

  1988cited by this paper
• Two cis-acting elements responsible for posttranscriptional trans-regulation of gene expression of human T-cell leukemia virus type I.

  1988cited by this paper
• Post‐transcriptional regulator (rex) of HTLV‐1 initiates expression of viral structural proteins but suppresses expression of regulatory proteins.

  1988cited by this paper
• Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genes

  1988influential reference
• trans-acting regulation of bovine leukemia virus mRNA processing

  1988cited by this paper
• Phosphorylation of the rev gene product of human immunodeficiency virus type 1

  1988cited by this paper
• Nucleotide sequence analysis of equine infectious anemia virus proviral DNA.

  1987cited by this paper
• Antigenic variation and lentivirus persistence: variations in envelope gene sequences during EIAV infection resemble changes reported for sequential isolates of HIV.

  1987cited by this paper
• Characterization of equine infectious anemia virus long terminal repeat

  1987cited by this paper
• The second pX product p27 x‐III of HTLV‐1 is required for gag gene expression

  1986cited by this paper
• Equine infectious anemia virus gag and pol genes: relatedness to visna and AIDS virus.

  1986cited by this paper
• A second post-transcriptional trans-activator gene required for HTLV-III replication

  1986cited by this paper
• HTLV-III expression and production involve complex regulation at the levels of splicing and translation of viral RNA.

  1986influential reference
• Equine infectious anemia virus: immunopathogenesis and persistence.

  1985cited by this paper
• Antigenic variation during persistent infection by equine infectious anemia virus, a retrovirus.

  1984cited by this paper
• Immunofluorescent localization of equine infectious anemia virus in tissue.

  1971cited by this paper

• SYNJ2BP Improves the Production of Lentiviral Envelope Protein by Facilitating the Formation of Mitochondrion-Associated Endoplasmic Reticulum Membrane

  2022cites this paper
• Identification of a Novel Post-transcriptional Transactivator from the Equine Infectious Anemia Virus

  2022cites this paper
• Equine Infectious Anemia

  2017cites this paper
• Identification of a homogenous structural basis for oligomerization by retroviral Rev-like proteins

  2017cites this paper
• The HIV-1 Rev response element (RRE) adopts alternative conformations that promote different rates of virus replication

  2015cites this paper
• Inactivated E. coli transformed with plasmids that produce dsRNA against infectious salmon anemia virus hemagglutinin show antiviral activity when added to infected ASK cells

  2015cites this paper
• Functional analysis of Rev binding region 2, a structural element of the EIAV Rev responsive element

  2015cites this paper
• Double-stranded RNA-specific adenosine deaminase 1 (ADAR1) promotes EIAV replication and infectivity.

  2015cites this paper
• Equine Viperin Restricts Equine Infectious Anemia Virus Replication by Inhibiting the Production and/or Release of Viral Gag, Env, and Receptor via Distortion of the Endoplasmic Reticulum

  2014cites this paper
• Genetic characterization by composite sequence analysis of a new pathogenic field strain of equine infectious anemia virus from the 2006 outbreak in Ireland.

  2013cites this paper
• Role of the Capsid Helix 4-5 Loop in Equine Infectious Anemia Virus Infection

  2013cites this paper
• Equine infectious anemia and equine infectious anemia virus in 2013: a review.

  2013cites this paper
• Development of an Equine-Tropic Replication-Competent Lentivirus Assay for Equine Infectious Anemia Virus-Based Lentiviral Vectors

  2012cites this paper
• Unique evolution characteristics of the envelope protein of EIAVLN40, a virulent strain of equine infectious anemia virus

  2011cites this paper
• A Long-Awaited Structure Is Rev-ealed

  2011cites this paper
• Gag Localization and Virus-Like Particle Release Mediated by the Matrix Domain of Human T-Lymphotropic Virus Type 1 Gag Are Less Dependent on Phosphatidylinositol-(4,5)-Bisphosphate than Those Mediated by the Matrix Domain of HIV-1 Gag

  2011cites this paper
• Converging Strategies in Expression of Human Complex Retroviruses

  2011cites this paper
• Molecular and biological characterization of equine infectious anemia virus Rev.

  2010cites this paper
• The developmental stage determines the distribution and duration of gene expression after early intra-amniotic gene transfer using lentiviral vectors

  2010cites this paper
• Rev: beyond nuclear export.

  2009cites this paper
• Cytokine detection in eiav-infected equine monocyte-derived macrophages using quantitative real-time polymerase chain reaction

  2009cites this paper
• Analysis of the EIAV Rev-Responsive Element (RRE) Reveals a Conserved RNA Motif Required for High Affinity Rev Binding in Both HIV-1 and EIAV

  2008cites this paper
• Gene transfer to ocular stem cells by early gestational intraamniotic injection of lentiviral vector.

  2007cites this paper
• Targeted gene transfer to fetal rat lung interstitium by ultrasound-guided intrapulmonary injection.

  2007cites this paper
• Resistance of human T cell leukemia virus type 1 to APOBEC3G restriction is mediated by elements in nucleocapsid

  2007cites this paper
• Characterization of Functional Domains of Equine Infectious Anemia Virus Rev Suggests a Bipartite RNA-Binding Domain

  2006cites this paper
• The S2 accessory gene of equine infectious anemia virus is essential for expression of disease in ponies.

  2006cites this paper
• Molecular analysis of the proviral DNA of equine infectious anemia virus in mules in Greece.

  2005cites this paper
• cis-Acting and trans-acting modulation of equine infectious anemia virus alternative RNA splicing.

  2004cites this paper
• Progress toward a combined bacterial and viral gene delivery system for mammalian cells

  2004cites this paper
• Equine Infectious Anemia Virus (EIAV): what has HIV's country cousin got to tell us?

  2004cites this paper
• The role of Rev-SR protein interactions in the regulation of equine infectious anemia virus replication

  2003cites this paper
• Enhancement of equine infectious anemia virus virulence by identification and removal of suboptimal nucleotides.

  2003cites this paper
• Multiple RNA splicing and the presence of cryptic RNA splice donor and acceptor sites may contribute to low expression levels and poor immunogenicity of potential DNA vaccines containing the env gene of equine infectious anemia virus (EIAV).

  2002cites this paper
• Design, production, safety, evaluation, and clinical applications of nonprimate lentiviral vectors.

  2002cites this paper
• Rev response elements (RRE) in lentiviruses: An RNAMotif algorithm‐based strategy for RRE prediction

  2002influential citation
• Binding Sites for Rev and ASF/SF2 Map to a 55-Nucleotide Purine-rich Exonic Element in Equine Infectious Anemia Virus RNA*

  2001cites this paper
• Suboptimal splice sites of equine infectious anaemia virus control Rev responsiveness.

  2000influential citation
• Binding of Equine Infectious Anemia Virus Rev to an Exon Splicing Enhancer Mediates Alternative Splicing and Nuclear Export of Viral mRNAs

  2000influential citation
• Selective Inhibition of Splicing at the Avian Sarcoma Virussrc 3′ Splice Site by Direct-Repeat Posttranscriptionalcis Elements

  2000cites this paper
• General effect of Sam68 on Rev/Rex regulated expression of complex retroviruses

  2000cites this paper
• The ins and outs of HIV Rev.

  1999cites this paper
• Stable gene transfer to the nervous system using a non-primate lentiviral vector

  1999cites this paper
• Genetic and molecular characterization of the Rev protein of equine infectious anemia virus

  1999cites this paper
• The S2 Gene of Equine Infectious Anemia Virus Is Dispensable for Viral Replication In Vitro

  1998cites this paper
• Regulation of equine infectious anemia virus expression.

  1998cites this paper
• Gene transfer vectors derived from equine infectious anemia virus

  1998cites this paper
• Regulation of Equine Infectious Anemia Virus Expression

  1998cites this paper
• Biological Characterization of Rev Variation in Equine Infectious Anemia Virus

  1998influential citation
• and Posttranscriptional Regulatory Element Not the Function of the Hepatitis B Virus Immunodeficiency Virus Rev Function but Anemia Virus Rev and Feline Leptomycin B Inhibits Equine Infectious

  1998cites this paper
• Differential Requirements for Alternative Splicing and Nuclear Export Functions of Equine Infectious Anemia Virus Rev Protein

  1998cites this paper
• X-I and X-II open reading frames of HTLV-I are not required for virus replication or for immortalization of primary T-cells in vitro.

  1997cites this paper
• Interactions among SR proteins, an exonic splicing enhancer, and a lentivirus Rev protein regulate alternative splicing

  1996cites this paper
• Definition of the RRE binding and activation domains of the caprine arthritis encephalitis virus Rev protein.

  1996cites this paper
• Molecular biology of the feline immunodeficiency virus auxiliary genes.

  1996cites this paper
• Expression and functional characterisation of the Rev gene product of Maedi Visna virus EV-1

  1996cites this paper
• Physical and Functional Characterization of Long Terminal Repeat of Equine Infectious Anemia Virus.

  1996cites this paper
• SR protein splicing factors interact with the Rous sarcoma virus negative regulator of splicing element

  1996cites this paper
• Inhibitory activity of the equine infectious anemia virus major 5' splice site in the absence of Rev

  1996influential citation
• Replication in vitro and in vivo of an equine infectious anemia virus mutant deficient in dUTPase activity

  1995cites this paper
• Nucleotide sequence analysis of Jembrana disease virus: a bovine lentivirus associated with an acute disease syndrome.

  1995cites this paper
• Virions released from cells transfected with a molecular clone of human T-cell leukemia virus type I give rise to primary and secondary infections of T cells

  1995cites this paper
• Translational Studies of Equine Infectious Anemia Virus RNA and Analysis of the Viral Regulatory Proteins.

  1994influential citation