The ins and outs of HIV Rev.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Archives of Biochemistry and Biophysics

• Publication date

  1999-05-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1006/ABBI.1999.1207PMID 10328811
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Nucleoporins Nup98 and Nup214 Participate in Nuclear Export of Human Immunodeficiency Virus Type 1 Rev

  1999cited by this paper
• Inhibition of Human Immunodeficiency Virus Rev and Human T-Cell Leukemia Virus Rex Function, but Not Mason-Pfizer Monkey Virus Constitutive Transport Element Activity, by a Mutant Human Nucleoporin Targeted to Crm1

  1998cited by this paper
• Overexpression of the Nucleoporin CAN/NUP214 Induces Growth Arrest, Nucleocytoplasmic Transport Defects, and Apoptosis

  1998cited by this paper
• Nuclear export of cyclin B1 and its possible role in the DNA damage‐induced G2 checkpoint

  1998cited by this paper
• Leptomycin B‐sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation

  1998cited by this paper
• Regulation of a nuclear export signal by an adjacent inhibitory sequence: the effector domain of the influenza virus NS1 protein.

  1998cited by this paper
• Nuclear-cytoplasmic shuttling of C-ABL tyrosine kinase.

  1998cited by this paper
• ICP27 mediates HSV RNA export by shuttling through a leucine-rich nuclear export signal and binding viral intronless RNAs through an RGG motif.

  1998cited by this paper
• and Posttranscriptional Regulatory Element Not the Function of the Hepatitis B Virus Immunodeficiency Virus Rev Function but Anemia Virus Rev and Feline Leptomycin B Inhibits Equine Infectious

  1998cited by this paper
• Transport of macromolecules between the nucleus and the cytoplasm.

  1998cited by this paper
• The influenza virus NEP (NS2 protein) mediates the nuclear export of viral ribonucleoproteins

  1998cited by this paper
• Nuclear export of actin: a novel mechanism regulating the subcellular localization of a major cytoskeletal protein

  1998cited by this paper
• Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA.

  1997cited by this paper
• Interactions between HIV Rev and nuclear import and export factors: the Rev nuclear localisation signal mediates specific binding to human importin-beta.

  1997cited by this paper
• Viral RNA export.

  1997cited by this paper
• CRM1 is responsible for intracellular transport mediated by the nuclear export signal

  1997cited by this paper
• Exportin 1 (Crm1p) is an essential nuclear export factor.

  1997cited by this paper
• The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus

  1997cited by this paper
• Rapid targeting of nuclear proteins to the cytoplasm.

  1997cited by this paper
• CRM1 is an export receptor for leucine-rich nuclear export signals.

  1997cited by this paper
• Oligomerization of HIV-1 Rev mutants in the cytoplasm and during nuclear import.

  1997cited by this paper
• Nuclear export of the E1B 55‐kDa and E4 34‐kDa adenoviral oncoproteins mediated by a rev‐like signal sequence

  1997cited by this paper
• Nuclear–Cytoplasmic Shuttling of the Focal Contact Protein, Zyxin: A Potential Mechanism for Communication between Sites of Cell Adhesion and the Nucleus

  1997cited by this paper
• A Novel Regulatory Mechanism in the Mitogen-activated Protein (MAP) Kinase Cascade

  1997cited by this paper
• The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88

  1997cited by this paper
• Characterization of the nuclear export signal of human T-cell lymphotropic virus type 1 Rex reveals that nuclear export is mediated by position-variable hydrophobic interactions

  1996cited by this paper
• Deep penetration of an α-helix into a widened RNA major groove in the HIV-1 rev peptide–RNA aptamer complex

  1996cited by this paper
• Nucleocytoplasmic Transport

  1996cited by this paper
• Protein sequence requirements for function of the human T-cell leukemia virus type 1 Rex nuclear export signal delineated by a novel in vivo randomization-selection assay

  1996cited by this paper
• Human immunodeficiency virus type 1 Rev function requires continued synthesis of its target mRNA

  1996cited by this paper
• HIV Rev uses a conserved cellular protein export pathway for the nucleocytoplasmic transport of viral RNAs.

  1996cited by this paper
• NMR solution structure of the RNA-binding peptide from human immunodeficiency virus (type 1) Rev.

  1995cited by this paper
• Distinct functions for the two importin subunits in nuclear protein import

  1995cited by this paper
• Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope.

  1995cited by this paper
• A nuclear localization domain in the hnRNP A1 protein

  1995cited by this paper
• Identification of a signal for rapid export of proteins from the nucleus.

  1995cited by this paper
• The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs.

  1995cited by this paper
• Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences.

  1995cited by this paper
• The nuclear pore complex.

  1995cited by this paper
• Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins.

  1995cited by this paper
• The HIV-1 Rev trans-activator shuttles between the nucleus and the cytoplasm.

  1994cited by this paper
• Equine infectious anemia virus trans-regulatory protein Rev controls viral mRNA stability, accumulation, and alternative splicing

  1994cited by this paper
• Isolation of a protein that is essential for the first step of nuclear protein import.

  1994cited by this paper
• Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor [published erratum appears in J Cell Biol 1994 Jan;124(1-2):217]

  1993cited by this paper
• The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

  1993cited by this paper
• Rev and the fate of pre-mRNA in the nucleus: implications for the regulation of RNA processing in eukaryotes

  1993cited by this paper
• Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm

  1992cited by this paper
• Specific binding of a basic peptide from HIV‐1 Rev.

  1992cited by this paper
• trans-dominant inhibition of human immunodeficiency virus type 1 Rev occurs through formation of inactive protein complexes

  1992cited by this paper
• Mutational definition of the human immunodeficiency virus type 1 Rev activation domain

  1991cited by this paper
• Effector domains of human immunodeficiency virus type 1 Rev and human T-cell leukemia virus type I Rex are functionally interchangeable and share an essential peptide motif

  1991cited by this paper
• Rev is necessary for translation but not cytoplasmic accumulation of HIV-1 vif, vpr, and env/vpu 2 RNAs.

  1991cited by this paper
• Oligomerization and RNA binding domains of the type 1 human immunodeficiency virus Rev protein: a dual function for an arginine-rich binding motif.

  1991cited by this paper
• HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: implications for HIV-1 latency.

  1991cited by this paper
• Identification of sequences important in the nucleolar localization of human immunodeficiency virus Rev: relevance of nucleolar localization to function

  1990cited by this paper
• Feedback regulation of human immunodeficiency virus type 1 expression by the Rev protein

  1990cited by this paper
• Mutational analysis of the human immunodeficiency virus type 1 Rev transactivator: essential residues near the amino terminus

  1990cited by this paper
• Regulation by HIV Rev depends upon recognition of splice sites.

  1989cited by this paper
• Functional dissection of the HIV-1 Rev trans-activator--derivation of a trans-dominant repressor of Rev function.

  1989cited by this paper
• rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA.

  1989cited by this paper
• The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

  1989cited by this paper
• The human immunodeficiency virus rev protein is a nuclear phosphoprotein.

  1989cited by this paper
• Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genes

  1988cited by this paper
• HTLV-III expression and production involve complex regulation at the levels of splicing and translation of viral RNA.

  1986cited by this paper

• HIV-1 latency: From acquaintance to confidant

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• LCRAnnotationsDB: a database of low complexity regions functional and structural annotations

  2024cites this paper
• Retroviral hijacking of host transport pathways for genome nuclear export

  2023cites this paper
• HIV RGB: Automated Single-Cell Analysis of HIV-1 Rev-Dependent RNA Nuclear Export and Translation Using Image Processing in KNIME

  2022cites this paper
• On the Regulated Nuclear Transport of Incompletely Spliced mRNAs by HIV-Rev Protein: A Minimal Dynamic Model

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• The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation

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• Circular RNAs: New Epigenetic Signatures in Viral Infections

  2020cites this paper
• Sequence and Functional Variation in the HIV-1 Rev Regulatory Axis.

  2020cites this paper
• An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing

  2020cites this paper
• Computational approaches for improving treatment and prevention of viral infections

  2019cites this paper
• Implication of B23/NPM1 in Viral Infections, Potential Uses of B23/NPM1 Inhibitors as Antiviral Therapy.

  2019cites this paper
• Structural and Functional Characterization of RNA-binding Site of Rev and Rev-Response-Element RNA Complex via All Atom Molecular Dynamics Simulations

  2018cites this paper
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  2018cites this paper
• A cis-Acting Element Downstream of the Mouse Mammary Tumor Virus Major Splice Donor Critical for RNA Elongation and Stability.

  2018cites this paper
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  2018cites this paper
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  2018cites this paper
• Screening for small molecule inhibitors of HIV-1 Gag expression.

  2017cites this paper
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  2017cites this paper
• Identification of small molecule modulators of HIV-1 Tat and Rev protein accumulation

  2017cites this paper
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  2017cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
• HIV-1 and M-PMV RNA Nuclear Export Elements Program Viral Genomes for Distinct Cytoplasmic Trafficking Behaviors

  2016cites this paper
• Nuclear Export Signal Masking Regulates HIV-1 Rev Trafficking and Viral RNA Nuclear Export

  2016cites this paper
• Manipulation of the N‐terminal sequence of the Borna disease virus X protein improves its mitochondrial targeting and neuroprotective potential

  2016cites this paper
• Nachweis der Interaktion zwischen Staufen-1 und den retroviralen Proteinen Rev und Rec mittels FRET-Assays

  2016cites this paper
• Biophysical Characterization of Nucleophosmin Interactions with Human Immunodeficiency Virus Rev and Herpes Simplex Virus US11

  2015cites this paper
• Identifying the Amino Acids Important for HIV Rev-Tubulin Interactions

  2015cites this paper
• HIV Rev Assembly on the Rev Response Element (RRE): A Structural Perspective

  2015cites this paper
• Human protein Staufen-2 promotes HIV-1 proliferation by positively regulating RNA export activity of viral protein Rev

  2014cites this paper
• HIV-1 Rev function and RNA nuclear-cytoplasmic export.

  2014cites this paper
• HIV-1-based lentiviral vectors.

  2014cites this paper
• Human retroviruses

  2014cites this paper
• Pokeweed antiviral protein alters splicing of HIV-1 RNAs, resulting in reduced virus production

  2014cites this paper
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  2014cites this paper
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  2014cites this paper
• Digoxin Suppresses HIV-1 Replication by Altering Viral RNA Processing

  2013cites this paper
• The arginine-rich RNA-binding motif of HIV-1 Rev is intrinsically disordered and folds upon RRE binding.

  2013cites this paper
• HIV-1 Rev multimerization: mechanism and insights.

  2013cites this paper
• Characterization of novel inhibitors of HIV-1 replication that function via alteration of viral RNA processing and rev function

  2013cites this paper
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  2013cites this paper
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  2013cites this paper
• HIV-1 and the Nucleolus: A Role for Nucleophosmin/NPM1 in Viral Replication: A Dissertation

  2013cites this paper
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  2013cites this paper
• Differential Effects of Tra2ß Isoforms on HIV-1 RNA Processing and Expression

  2013cites this paper
• Impact of Viral Factors on Subcellular Distribution and RNA Export Activity of HIV-1 Rev in Astrocytes 1321N1

  2013cites this paper
• RNA polymerase II transcription on the fast lane

  2012cites this paper
• Dynamic Post-Transcriptional Regulation of HIV-1 Gene Expression

  2012cites this paper
• Functional control of HIV-1 post-transcriptional gene expression by host cell factors

  2012cites this paper
• Nucleolar Protein Trafficking in Response to HIV-1 Tat: Rewiring the Nucleolus

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• ValidNESs: a database of validated leucine-rich nuclear export signals

  2012cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
• DDX1 Is an RNA-Dependent ATPase Involved in HIV-1 Rev Function and Virus Replication

  2011cites this paper
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  2011cites this paper
• Host proteins involved in HIV infection: new therapeutic targets.

  2010cites this paper
• The Role of Apoptosis in HeLa Cells Expressing HIV-1 Rev

  2010influential citation
• Domain- and nucleotide-specific Rev response element regulation of feline immunodeficiency virus production.

  2010cites this paper
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  2010cites this paper
• FUNKTIONELLE CHARAKTERISIERUNG DER HERV-K PROTEINE ENV UND REC

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  2010cites this paper
• Comparative analysis of RNA/protein dynamics for the arginine-rich-binding motif and zinc-finger-binding motif proteins encoded by HIV-1.

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  2010cites this paper
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  2009cites this paper
• Structural Model of the Rev Regulatory Protein from Equine Infectious Anemia Virus

  2009cites this paper
• The 5′-untranslated region of the mouse mammary tumor virus mRNA exhibits cap-independent translation initiation

  2009cites this paper
• Cellular proteins and HIV-1 Rev function.

  2009cites this paper
• Role of RNA structure and protein factors in the control of HIV-1 splicing.

  2009cites this paper
• How does the journey affect the message(RNA)?

  2009cites this paper
• Stable complex formation between HIV Rev and the nucleosome assembly protein, NAP1, affects Rev function.

  2009cites this paper
• Thermodynamic profiling of HIV RREIIB RNA-zinc finger interactions.

  2009cites this paper
• Cessation of HIV-1 transcription by inhibiting regulatory protein Rev-mediated RNA transport.

  2009cites this paper
• Characterization of Microtubule Depolymerization by the HIV Protein Rev

  2009cites this paper
• Effects of Sam68 on HIV-1 RNA Processing and Gene Expression

  2009cites this paper
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  2009cites this paper
• Mapping of determinants involved in the stimulation of HIV-1 expression by Sam68.

  2009cites this paper
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  2009cites this paper
• Nuclear‐Cytoplasmic Transport

  2009cites this paper
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  2007cites this paper
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  2007cites this paper
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  2007influential citation
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  2007cites this paper
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