Abnormal cortisol levels during the day and cortisol awakening response in first-episode psychosis: the role of stress and of antipsychotic treatment.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Schizophrenia Research

• Publication date

  2010-02-01

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1016/j.schres.2009.08.013PMID 19751968PMCID PMC3513410
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS).

  2009cited by this paper
• Gender differences in the association between childhood abuse and psychosis.

  2009influential reference
• The HPA axis in major depression: classical theories and new developments.

  2008cited by this paper
• Pituitary volume in unaffected relatives of patients with schizophrenia and bipolar disorder.

  2008influential reference
• Sex differences in the cortisol response to awakening in recent onset psychosis.

  2008influential reference
• Pituitary volume in psychosis: the first review of the evidence

  2008cited by this paper
• Glucocorticoid antagonists in neuropsychiatric [corrected] disorders.

  2008cited by this paper
• Stress and the hypothalamic pituitary adrenal axis in the developmental course of schizophrenia.

  2008cited by this paper
• Plasma cortisol-dehydroepiandrosterone (DHEA) ratios in schizophrenia and bipolar disorder.

  2007cited by this paper
• Cortisol levels in relation to hippocampal sub-regions in subjects with first episode schizophrenia.

  2007influential reference
• Circulatory neurosteroid levels in smoking and non-smoking chronic schizophrenia patients.

  2007cited by this paper
• The effects of olanzapine and fluphenazine on plasma cortisol, prolactin and muscle rigidity in schizophrenic patients: a double blind study.

  2007cited by this paper
• Stress-reactivity in psychosis: evidence for an affective pathway to psychosis.

  2007cited by this paper
• Cannabis use and psychiatric and cogitive disorders: the chicken or the egg?

  2007cited by this paper
• Changes in Neuroendocrine and Metabolic Hormones Induced by Atypical Antipsychotics in Normal-Weight Patients with Schizophrenia

  2007cited by this paper
• Cannabis-Induced Psychosis-Like Experiences Are Associated with High Schizotypy

  2006cited by this paper
• Incidence of schizophrenia and other psychoses in ethnic minority groups: results from the MRC AESOP Study

  2006cited by this paper
• Altered cortisol awakening response in posttraumatic stress disorder.

  2006cited by this paper
• The use of mifepristone in the treatment of neuropsychiatric disorders.

  2006cited by this paper
• Dexamethasone suppression test in first-episode schizophrenia.

  2006influential reference
• Heterogeneity in incidence rates of schizophrenia and other psychotic syndromes: findings from the 3-center AeSOP study.

  2006cited by this paper
• The hypothalamic-pituitary-adrenal (HPA) axis in habitual smokers.

  2006cited by this paper
• Clinical and Biological Effects of Mifepristone Treatment for Psychotic Depression

  2006cited by this paper
• The "delayed onset" of antipsychotic action--an idea whose time has come and gone.

  2006cited by this paper
• The atypical antipsychotics olanzapine and quetiapine, but not haloperidol, reduce ACTH and cortisol secretion in healthy subjects

  2006influential reference
• Different responses to dexamethasone and prednisolone in the same depressed patients

  2006cited by this paper
• Clinical and social determinants of duration of untreated psychosis in the AESOP first-episode psychosis study.

  2006cited by this paper
• Nocturnal hormone profiles in patients with schizophrenia treated with olanzapine.

  2006influential reference
• Increased salivary cortisol after waking in depression

  2005cited by this paper
• A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors.

  2005cited by this paper
• Childhood trauma, psychosis and schizophrenia: a literature review with theoretical and clinical implications

  2005influential reference
• Pituitary volume predicts future transition to psychosis in individuals at ultra-high risk of developing psychosis.

  2005influential reference
• Stress: the shared common component in major mental illnesses

  2005cited by this paper
• Increased Pituitary Volume in Antipsychotic-Free and Antipsychotic-Treated Patients of the Æsop First-Onset Psychosis Study

  2005influential reference
• Cortisol and Cytokines in Chronic and Treatment-Resistant Patients with Schizophrenia: Association with Psychopathology and Response to Antipsychotics

  2005influential reference
• The childhood experience of care and abuse questionnaire (CECA.Q): validation in a community series.

  2005influential reference
• Delta-9-tetrahydrocannabinol effects in schizophrenia: implications for cognition, psychosis, and addiction.

  2005cited by this paper
• What causes the onset of psychosis?

  2005influential reference
• Salivary cortisol response to awakening in chronic fatigue syndrome

  2004influential reference
• Pituitary volume in psychosis

  2004cited by this paper
• The Psychotomimetic Effects of Intravenous Delta-9-Tetrahydrocannabinol in Healthy Individuals: Implications for Psychosis

  2004cited by this paper
• Clinical studies on the mechanism of action of clozapine: the dopamine-serotonin hypothesis of schizophrenia

  2004cited by this paper
• Increased circulatory dehydroepiandrosterone and dehydroepiandrosterone-sulphate in first-episode schizophrenia: relationship to gender, aggression and symptomatology.

  2004cited by this paper
• The Awakening Cortisol Response: Methodological Issues and Significance

  2004cited by this paper
• Hypocortisolism and increased glucocorticoid sensitivity of pro-Inflammatory cytokine production in Bosnian war refugees with posttraumatic stress disorder.

  2004cited by this paper
• Preliminary evidence of an association between childhood abuse and cannabis dependence among African American first-episode schizophrenia-spectrum disorder patients.

  2004cited by this paper
• Neurobiological consequences of childhood trauma.

  2004cited by this paper
• Evidence of basal pituitary-adrenal overactivity in first episode, drug naïve patients with schizophrenia.

  2004influential reference
• Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change.

  2003cited by this paper
• The neuroendocrinology of chronic fatigue syndrome.

  2003cited by this paper
• Increase in concentration of waking salivary cortisol in recovered patients with depression.

  2003cited by this paper
• Impaired fasting glucose tolerance in first-episode, drug-naive patients with schizophrenia.

  2003influential reference
• Lower Cortisol Levels in Depressed Patients with Comorbid Post-Traumatic Stress Disorder

  2003cited by this paper
• Social environment, ethnicity and schizophrenia. A case-control study.

  2002cited by this paper
• Commentary on "Clinical studies on the mechanism of action of clozapine; the dopamine–serotonin hypothesis of schizophrenia." Psychopharmacology (1989) 99:S18–S27

  2002cited by this paper
• Childhood Experience of Care and Abuse Questionnaire (CECA.Q)

  2002cited by this paper
• Biology of posttraumatic stress disorder.

  2001influential reference
• Emotional reactivity to daily life stress in psychosis.

  2001cited by this paper
• The Effect of Olanzapine Treatment on m-Chlorophenylpiperazine-Induced Hormone Release in Schizophrenia

  2001cited by this paper
• Pituitary-adrenal and autonomic responses to stress in women after sexual and physical abuse in childhood.

  2000cited by this paper
• Selective impairments in the stress response in schizophrenic patients

  2000cited by this paper
• Switch from neuroleptics to clozapine does not influence pituitary-gonadal axis hormone levels in male schizophrenic patients.

  1999cited by this paper
• Blunted cortisol response to a psychosocial stressor in schizophrenia.

  1998cited by this paper
• Neurochemical variables in schizophrenic patients during switching from neuroleptics to clozapine.

  1998cited by this paper
• The dexamethasone suppression test in schizophrenia

  1998cited by this paper
• Schizophrenia: a neural diathesis-stress model.

  1997cited by this paper
• Combined dexamethasone/corticotropin-releasing hormone test in patients with schizophrenia and in normal controls: II.

  1995cited by this paper
• Life Events and Psychosis

  1993cited by this paper
• Dexamethasone suppression test in schizophrenia: relationship to symptomatology, ventricular enlargement, and outcome.

  1991cited by this paper
• A polydiagnostic application of operational criteria in studies of psychotic illness. Development and reliability of the OPCRIT system.

  1991influential reference
• The List of Threatening Experiences: the reliability and validity of a brief life events questionnaire

  1990cited by this paper
• Neurobiological effects of lumbar puncture stress in psychiatric patients and healthy volunteers.

  1988cited by this paper
• Perceived stress in a probability sample of the United States

  1988cited by this paper
• The dexamethasone suppression test in newly hospitalized schizophrenic patients.

  1985cited by this paper
• Dexamethasone suppression test in schizophrenia.

  1983cited by this paper
• Psychoendocrinology of ego disintegration.

  1970influential reference

• Indirect effects of psychiatric symptoms on the association between childhood trauma and motivation orientation.

  2025cites this paper
• Awakening not associated with an increased rate of cortisol secretion

  2025cites this paper
• Mediation by elevated prolactin in the relationship between childhood trauma and first-episode drug-naïve schizophrenia

  2025cites this paper
• The Mini-TRH Test, Dopamine Transmission, and Schizophrenia Symptoms

  2025cites this paper
• Cortisol in schizophrenia spectrum disorders: A comprehensive meta-analysis.

  2025cites this paper
• Clarithromycin-Induced Psychosis: When Is Delirium Not Delirium?

  2025cites this paper
• Cortisol response patterns to stress correlated to white matter integrity and duration of illness in patients with schizophrenia.

  2025cites this paper
• The Etiological Role of Impaired Neurogenesis in Schizophrenia: Interactions with Inflammatory, Microbiome and Hormonal Signaling

  2025cites this paper
• Salivary cortisol measures across the clinical stages of psychosis: An individual participant data (IPD) meta-analysis.

  2025cites this paper
• Perceived Stress and Hippocampal Volume in Psychosis.

  2024cites this paper
• Altered brain and physiological stress responses in early psychosis.

  2024cites this paper
• Threat Responses in Schizophrenia: A Negative Valence Systems Framework

  2024cites this paper
• The day-to-day influence of trauma exposure and sleep dysfunction on everyday stress in youth at familial high-risk for psychotic disorders

  2024cites this paper
• Neurofeedback Technology Reduces Cortisol Levels in Bruxismitle Patients: Assessment of Cerebral Activity and Anxiolytic Effects of Origanum majorana Essential Oil

  2024cites this paper
• Cortisol and C-reactive protein (CRP) regulation in severe mental disorders.

  2024cites this paper
• Corticosteroid-Induced Psychiatric Disorders: Mechanisms, Outcomes, and Clinical Implications

  2024cites this paper
• Specific Reduction in the Cortisol Awakening Response after Socio-Affective Mental Training

  2023cites this paper
• The neural, stress hormone and inflammatory correlates of childhood deprivation and threat in psychosis: A systematic review.

  2023cites this paper
• Stressful life events and relapse of psychosis: analysis of causal association in a 2-year prospective observational cohort of individuals with first-episode psychosis in the UK

  2023cites this paper
• Associations between saliva alpha-amylase, heart rate variability, saliva cortisol and cognitive performance in individuals at ultra high-risk for psychosis.

  2023cites this paper
• Stress, Environment and Early Psychosis

  2023cites this paper
• Blood concentrations of anterior pituitary hormones in drug-naïve people with first-episode psychosis: A systematic review and meta-analysis.

  2023cites this paper
• Interaction between high interleukin-2 and high cortisol levels is associated with psychopathology in patients with chronic schizophrenia.

  2023cites this paper
• Disentangling the effects of depression and perceived stress on cortisol levels in individuals with obesity: Preliminary results from a cross-sectional study.

  2023cites this paper
• Examining the psychobiological response to acute social stress across clinical stages and symptom trajectories in the early psychosis continuum.

  2023cites this paper
• The Translational Future of Stress Neurobiology and Psychosis Vulnerability: A Review of the Evidence

  2023cites this paper
• Childhood trauma, perceived stress and anhedonia in individuals at clinical high risk for psychosis: multigroup mediation analysis

  2023cites this paper
• Towards Novel Potential Molecular Targets for Antidepressant and Antipsychotic Pharmacotherapies

  2023cites this paper
• Environmental Risk Factors and Cognitive Outcomes in Psychosis: Pre-, Perinatal, and Early Life Adversity.

  2022cites this paper
• Time course of epigenetic modulation in response to concurrent exercise training in patients with schizophrenia

  2022cites this paper
• Receptor-Mediated AKT/PI3K Signalling and Behavioural Alterations in Zebrafish Larvae Reveal Association between Schizophrenia and Opioid Use Disorder

  2022cites this paper
• STUDY OF LIFE EVENTS AND PREMORBID FUNCTION IN RECENT ONSET SCHIZOPHRENIA

  2022cites this paper
• Childhood adversity, symptoms, and cortisol in first episode psychosis: a cross-sectional, secondary, observational analysis of a subsample of FEP patients

  2022cites this paper
• Can dogs serve as stress mediators to decrease salivary cortisol levels in a population of liberal arts college undergraduate students?

  2022cites this paper
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  2022cites this paper
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  2021cites this paper
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  2021cites this paper
• Perceived stress influences anhedonia and social functioning in a community sample enriched for psychosis-risk.

  2021cites this paper
• Biomarkers

  2021cites this paper
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  2021cites this paper
• Adverse Childhood Experiences and Neurocognition in Schizophrenia Spectrum Disorders: Age at First Exposure and Multiplicity Matter

  2021cites this paper
• HPA Axis in the Pathomechanism of Depression and Schizophrenia: New Therapeutic Strategies Based on Its Participation

  2021influential citation
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper