Coupled dynamics of voltage and calcium in paced cardiac cells.

We investigate numerically and analytically the coupled dynamics of transmembrane voltage and intracellular calcium cycling in paced cardiac cells using a detailed physiological model, and its reduction to a three-dimensional discrete map. The results provide a theoretical framework to interpret various experimentally observed modes of instability ranging from electromechanically concordant and discordant alternans to quasiperiodic oscillations of voltage and calcium.

• Publication year

  2004

• Venue

  Physical review. E, Statistical, nonlinear, and soft matter physics

• Publication date

  2004-05-11

• Fields of study

  Medicine, Physics

• Identifiers
  DOI 10.1103/PhysRevE.71.021903arXiv physics/0405048PMID 15783348PMCID PMC4278950
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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