Pharmacokinetics of sodium nitrite-induced methemoglobinemia in the rat.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Drug Metabolism And Disposition

• Publication date

  2002-06-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1124/DMD.30.6.676PMID 12019195
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Membrane effects of nitrite-induced oxidation of human red blood cells.

  1999cited by this paper
• Direct Measurement of Nitrite Transport Across Erythrocyte Membrane Vesicles Using the Fluorescent Probe, 6-Methoxy-N-(3-sulfopropyl) quinolinium

  1997influential reference
• Physiologic indirect response models characterize diverse types of pharmacodynamic effects

  1994cited by this paper
• A block organized model builder

  1994cited by this paper
• A physiologically based model for gastrointestinal absorption and excretion of chemicals carried by lipids.

  1993influential reference
• Physiological Parameters in Laboratory Animals and Humans

  1993influential reference
• Distribution of cardiac output during diurnal changes of activity in rats.

  1991influential reference
• Stress effects on gastrointestinal transit in the rat.

  1989cited by this paper
• Mechanism of autocatalytic oxidation of oxyhemoglobin by nitrite.

  1987cited by this paper
• Oxidation reaction of human oxyhemoglobin with nitrite: a reexamination.

  1987influential reference
• Transport and Diffusion Across Cell Membranes

  1986cited by this paper
• SCoP: an interactive simulation control program for micro- and minicomputers.

  1986cited by this paper
• Differential inhibition of rat tissue catalase by cyanamide.

  1986influential reference
• Inhibition of nitrate-induced increase of plasma nitrite and methemoglobinemia in rats by simultaneous feeding of ascorbic acid or tocopherol.

  1984cited by this paper
• Influence of dietary iron deficiency on hemoglobin, myoglobin, their respective reductases, and skeletal muscle mitochondrial respiration.

  1981influential reference
• National Toxicology Program

  1981cited by this paper
• Introduction to System Sensitivity Theory

  1980cited by this paper
• In vivo studies on methemoglobin formation by sodium nitrite

  1980cited by this paper
• Stoichiometry of the reaction of oxyhemoglobin with nitrite.

  1979influential reference
• Some features of the reaction between cobaltinitrite and hemoglobin.

  1970cited by this paper
• Chemically induced methemoglobinemias in the mouse.

  1967cited by this paper
• The nitrite methemoglobin complex--its significance in methemoglobin analyses and its possible role in methemoglobinemia.

  1967influential reference
• Species differences in methemoglobin reductase activity.

  1966influential reference
• Nitrite and thiosulfate therapy in cyanide poisoning.

  1952influential reference

• Effect of Fertigated Water Consumption on the Immune Responsiveness and Antipredator Behavior of Red-Legged Partridge Chicks

  2025cites this paper
• A Comparative Analysis of Heart Rate Dynamics in Female and Fetal Rats Exposed to Hemic Hypoxia

  2025cites this paper
• Characteristics of auto-quantified tumor-infiltrating lymphocytes and the prognostic value in adenocarcinoma of the esophagogastric junction, gastric adenocarcinoma, and esophageal squamous cell carcinoma

  2024cites this paper
• Nitrite decreases sickle hemoglobin polymerization in vitro independently of methemoglobin formation.

  2023cites this paper
• Nitrite Toxicity: Chemical Analysis, Metabolism, and Health Effects

  2022cites this paper
• Bis4-(4 ́ -hydroxy-3 ́ -methoxy benzylidine aminophenyl) telluride prevents sodium nitrite induced changes in haematological parameters of adult's

  2022cites this paper
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• Transcutaneous Monitoring of Hemoglobin Derivatives Using Camera-Based Diffuse Reflectance Spectroscopy

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• Organosilica colloids as nitric oxide carriers: Pharmacokinetics and biocompatibility.

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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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• Transcutaneous monitoring of hemoglobin derivatives during methemoglobinemia using spectral diffuse reflectance imaging

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  2019cites this paper
• Carnosine and l-arginine attenuate the downregulation of brain monoamines and gamma aminobutyric acid; reverse apoptosis and upregulate the expression of angiogenic factors in a model of hemic hypoxia in rats

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• Nitric oxide inhibits hypoxia‐induced impairment of human RBC deformability through reducing the cross‐linking of membrane protein band 3

  2018cites this paper
• Effects of Succinate-Based Antioxidant on in vitro Conversion of Methemoglobin in Oxyhemoglobin

  2018cites this paper
• Methylene Blue Counteracts H2S-Induced Cardiac Ion Channel Dysfunction and ATP Reduction

  2018cites this paper
• Inhibition of Glutathione Synthesis via Decreased Glucose Metabolism in Stored RBCs

  2018cites this paper
• Secondary poisoning risk for encapsulated sodium nitrite, a new tool for possum control

  2018influential citation
• Revisiting the physiological effects of methylene blue as a treatment of cyanide intoxication

  2018cites this paper
• Cholinesterase Activities and Oxidative Stress in Cattle Experimentally Exposed to Nitrate / Nitrite in Cultivated Pasture with Different Fertilization Schemes

  2018cites this paper
• Ameliorative Effects of Ascorbic Acid ( Vit . C ) Against Sodium Nitrite Toxicity in Albino Rats : Hematological , Biochemical and Histopathological Studies

  2017cites this paper
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  2016cites this paper
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  2014cites this paper
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  2014influential citation
• Red blood cell storage increases hypoxia‐induced nitric oxide bioavailability and methemoglobin formation in vitro and in vivo

  2014cites this paper
• How biology handles nitrite.

  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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• Molecular Components of Nitrate and Nitrite Efflux in Yeast

  2013cites this paper
• Inhibitory effects of hyperoxia and methemoglobinemia on H(2)S induced ventilatory stimulation in the rat.

  2012cites this paper
• Concentration and Time - Antioxidant Effect Relationship of Anthocyanins in Sodium Nitrite and Azo Compounds-Induced Hemoglobin Oxidation and Erythrocytes Membrane Damage; In Vitro and In Vivo Studies

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• Kinetics and mechanism of hemoglobin oxidation by nitroethane

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• i-Nitrite Therapy for Treatment of Peripheral Arterial Disease

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• Amyl and Butyl Nitrites

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• Sodium nitrite-induced hematological and hemorheological changes in rats

  2012cites this paper
• Externalized ATP in intact erythrocyte suspensions: modulation and determination

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• The protective effect of vitamin A against sodium nitrate induced toxicity in liver and kidney of albino rats: histological and ultrastructural study

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• Caracterización de los transportadores de nitrato y de potasio en la levadura Hansenula polymorpha

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• Inorganic nitrite therapy: historical perspective and future directions.

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• Brain Nitric Oxide Inactivation Is Governed by the Vasculature

  2011cites this paper
• Hydrogen sulfide oxidation and the arterial chemoreflex: effect of methemoglobin.

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  2010influential citation
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