Effect of insulin on adenosine 3',5'-monophosphate in the rat epididymal fat pad.

Abstract Insulin rapidly lowered intracellular cyclic adenosine 3',5'-monophosphate levels in adipose tissue incubated with epinephrine or epinephrine and caffeine. This effect was not due to increased escape of cyclic AMP to the medium. Since cyclic AMP has been implicated in the lipolytic action of epinephrine, these data suggest that the antilipolytic action of insulin is due at least in part to the suppression of cyclic AMP levels.

• Publication year

  1966

• Venue

  Journal of Biological Chemistry

• Publication date

  1966-04-10

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/s0021-9258(18)96764-5PMID 5946622
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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