Biosynthesis of monoterpenes: enzymatic concersion of neryl pyrophosphate to 1,8-cineole, alpha-terpineol, and cyclic monoterpene hydrocarbons by a cell-free preparation from sage (Salvia officinalis).

No abstract is available for this paper.

• Publication year

  1976

• Venue

  Archives of Biochemistry and Biophysics

• Publication date

  1976-10-01

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/0003-9861(76)90217-4PMID 984853
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Kaurene synthetase from plastids of developing plant tissues.

  1975cited by this paper
• Enzymatic cyclization of neryl pyrophosphate to -terpineol by cell-free extracts from peppermint.

  1973cited by this paper
• Fatty acid synthesis in galacto lipids and phospho lipids in broad bean leaves

  1973cited by this paper
• The constituent cutin acids of cranbury cuticle

  1972cited by this paper
• The biosynthesis of monoterpenes.

  1972cited by this paper
• Terpene biosynthesis from geranyl and neryl pyrophosphates by enzymes from orange flavedo

  1971cited by this paper
• Biosynthesis of cyclic diterpenes in extracts from seedlings of Ricinus communis L. II. Conversion of geranylgeranyl pyrophosphate into diterpene hydrocarbons and partial purification of the cyclization enzymes.

  1970cited by this paper
• Evidence for metabolic turnover of monoterpenes in peppermint.

  1969cited by this paper
• Studies in terpenoid biosynthesis—III. The incorporation of geranyl pyrophosphate into cineole☆

  1968cited by this paper
• Separation of water-soluble steroid and carotenoid precursors by DEAE-cellulose column chromatography.

  1968cited by this paper
• Biosynthesis of gibberellins. II. Enzymic cyclization of geranylgeranyl pyrophosphate to kaurene.

  1967cited by this paper
• Die hydrolyse von phosphaten und pyrophosphaten einiger monoterpenalkohole

  1967cited by this paper
• Acid catalyzed hydrolysis of neryl pyrophosphate and geranyl pyrophosphate.

  1967cited by this paper
• Effects of light and temperature on the monoterpenes of peppermint.

  1967cited by this paper
• Methods in Enzymology , Vol

  1966cited by this paper
• The Cleavage of Ethers by Triphenyldibromophosphorane

  1964cited by this paper
• Synthese von Geranyl‐ und Farnesyl‐pyrophosphat

  1959cited by this paper
• The estimation of inorganic phosphate in the presence of adenosine triphosphate.

  1959cited by this paper
• The isoprene rule and the biogenesis of terpenic compounds

  1953cited by this paper
• Über α‐ und β‐Cinensäure

  1933cited by this paper
• Zur Kenntniss der Terpene und der ätherischen Oele: Ueberführung von Verbindungen der Terpenreihe in Hydro‐m‐xylol

  year unknowncited by this paper

• Structural Characterization of Early Michaelis Complexes in the Reaction Catalyzed by (+)-Limonene Synthase from Citrus sinensis Using Fluorinated Substrate Analogues.

  2017cites this paper
• Identification and Characterization of a Novel Monoterpene Synthase from Soybean Restricted to Neryl Diphosphate Precursor

  2013cites this paper
• Genomic DNA extraction from seed induced callus and explants in Salvia L. species for utilization in secondary metabolite production

  2012cites this paper
• SALINITY EFFECTS ON GROWTH, ESSENTIAL OIL YIELD AND COMPOSITION AND PHENOLIC COMPOUNDS CONTENT OF MARJORAM (ORIGANUM MAJORANA L.) LEAVES

  2011cites this paper
• Essential Oil Variation of Salvia officinalis Leaves during Vegetation after Treatment with Foliar Fertilizer and Thidiazuron

  2010cites this paper
• Effects of foliar fertilization and arbuscular mycorrhizal colonization on Salvia officinalis L. growth, antioxidant capacity, and essential oil composition.

  2010cites this paper
• Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate

  2009cites this paper
• Consumer rejection threshold for 1,8-cineole (eucalyptol) in Australian red wine

  2009cites this paper
• Rendimento de oleo essencial de Salvia officinalis L. sob acao de . reguladores vegetais

  2007cites this paper
• Brushes with sage.

  2006cites this paper
• Glandular hairs and essential oils in micropropagated plants of Salvia officinalis L.

  2005cites this paper
• Monoterpenoid accumulation in 1,8-cineole, terpinolene and terpinen-4-ol chemotypes of Melaleuca alternifolia seedlings.

  2003cites this paper
• THE SEQUENTIAL ONSET OF TERPENOID BIOGENESIS IN SEEDLINGS: IMPLICATIONS FOR MELALEUCA ALTERNIFOLIA CHEMOTYPE IDENTIFICATION PRIOR TO PLANTATION ESTABLISHMENT

  2003cites this paper
• Monoterpenoid accumulation inMelaleuca alternifoliaseedlings

  2002cites this paper
• Monoterpenoid accumulation in Melaleuca alternifolia seedlings.

  2002cites this paper
• Secretion Constituents of Leaf Glandular Trichome of Salvia officinalis L.

  1999cites this paper
• 2.05 – Monoterpene Biosynthesis

  1999cites this paper
• Monoterpene Synthases from Common Sage (Salvia officinalis)*

  1998cites this paper
• Monoterpene synthases from gymnosperms and angiosperms: stereospecificity and inactivation by cysteinyl- and arginyl-directed modifying reagents.

  1995cites this paper
• Monoterpene biosynthesis: isotope effects associated with bicyclic olefin formation catalyzed by pinene synthases from sage (Salvia officinalis).

  1994cites this paper
• Stereochemistry of the proton elimination in the formation of (+)- and (-)-alpha-pinene by monoterpene cyclases from sage (Salvia officinalis).

  1994cites this paper
• Biosynthesis of monoterpenes: partial purification, characterization, and mechanism of action of 1,8-cineole synthase.

  1994cites this paper
• Monoterpene synthases of Pinus contorta and related conifers. A new class of terpenoid cyclase.

  1994cites this paper
• Biosynthesis of the diterpene cis-abienol in cell-free extracts of tobacco trichomes.

  1994cites this paper
• 4S-limonene synthase from the oil glands of spearmint (Mentha spicata). cDNA isolation, characterization, and bacterial expression of the catalytically active monoterpene cyclase.

  1993cites this paper
• Procedures for the isolation and quantification of the intermediates of the mevalonic acid pathway.

  1993cites this paper
• Absence of rapid terpene turnover in several diverse species of terpene-accumulating plants

  1993cites this paper
• Production and characterization of polyclonal antibodies in rabbits to 4S-limonene synthase from spearmint (Mentha spicata).

  1993cites this paper
• Cis-dihydroagarofuran from Prostanthera sp. aff. ovalifolia

  1993cites this paper
• Evidence for an essential histidine residue in 4S-limonene synthase and other terpene cyclases.

  1992cites this paper
• Genetic control of the enzymatic formation of cyclic monoterpenoids inPerilla frutescens

  1992cites this paper
• Characterization and mechanism of (4S)-limonene synthase, a monoterpene cyclase from the glandular trichomes of peppermint (Mentha x piperita).

  1992cites this paper
• Purification of 4S-limonene synthase, a monoterpene cyclase from the glandular trichomes of peppermint (Mentha x piperita) and spearmint (Mentha spicata).

  1992cites this paper
• Comparison of Two Monoterpene Cyclases Isolated from Higher Plants; γ-Terpinene Synthase from Thymus Vulgaris, and Limonene Synthase from Mentha x Piperita

  1992cites this paper
• Enzymatic synthesis of labelled geraniol

  1991cites this paper
• Purification and characterization of the monoterpene cyclase gamma-terpinene synthase from Thymus vulgaris.

  1991cites this paper
• Isotopically sensitive branching as a tool for evaluating multiple product formation by monoterpene cyclases

  1991cites this paper
• Metabolism of Monoterpenes in Cell Cultures of Common Sage (Salvia officinalis) : Biochemical Rationale for the Lack of Monoterpene Accumulation.

  1990cites this paper
• Regulation of monoterpene biosynthesis in higher plants

  1990cites this paper
• Uncompetitive inhibition of monoterpene cyclases by an analog of the substrate geranyl pyrophosphate and inhibition of monoterpene biosynthesis in vivo by an analog of geraniol.

  1990cites this paper
• Monoterpene biosynthesis: mechanistic evaluation of the geranyl pyrophosphate:(-)-endo-fenchol cyclase from fennel (Foeniculum vulgare).

  1989cites this paper
• Biosynthesis of monoterpenes. Stereochemical implications of acyclic and monocyclic olefin formation by (+)- and (-)-pinene cyclases from sage.

  1989cites this paper
• Monoterpene biosynthesis: mechanism and stereochemistry of the enzymatic cyclization of geranyl pyrophosphate to (+)-cis- and (+)-trans-sabinene hydrate.

  1989cites this paper
• Facile enzymatic synthesis of labelled geranyl pyrophosphate

  1989cites this paper
• Geranyl pyrophosphate synthase: characterization of the enzyme and evidence that this chain-length specific prenyltransferase is associated with monoterpene biosynthesis in sage (Salvia officinalis).

  1989cites this paper
• Analysis of terpene variation in leaves and fruits of Citrus unshiu Marc. during ontogenesis

  1989cites this paper
• Monoterpene cyclases: physicochemical features required for pyrophosphate binding determined from inhibition by structural analogs.

  1988cites this paper
• Biosynthesis of monoterpenes. Enantioselectivity in the enzymatic cyclization of (+)- and (-)-linalyl pyrophosphate to (+)- and (-)-pinene and (+)- and (-)-camphene.

  1988cites this paper
• Subcellular distribution of enzymes of mono- and sesquiterpene biosynthesis in plant tissues.

  1988cites this paper
• Selective determination of organofluorine compounds by capillary column gas chromatography with an atmospheric pressure helium microwave-induced plasma detector

  1988cites this paper
• Applications of gas chromatography to the study of terpenoid metabolism.

  1988cites this paper
• Monoterpene cyclases. Stereoelectronic requirements for substrate binding and ionization.

  1987cites this paper
• Biosynthesis of the sesquiterpene patchoulol from farnesyl pyrophosphate in leaf extracts of Pogostemon cablin (patchouli): mechanistic considerations.

  1987cites this paper
• Isotopically sensitive branching in the formation of cyclic monoterpenes: proof that (-)-alpha-pinene and (-)-beta-pinene are synthesized by the same monoterpene cyclase via deprotonation of a common intermediate.

  1987cites this paper
• Metabolism of Monoterpenes : Metabolic Fate of (+)-Camphor in Sage (Salvia officinalis).

  1987cites this paper
• Biosynthesis of monoterpenes. Enantioselectivity in the enzymatic cyclization of (+)- and (-)-linalyl pyrophosphate to (+)- and (-)-bornyl pyrophosphate.

  1986cites this paper
• Monoterpene formation by leucoplasts of Citrofortunella mitis and Citrus unshiu

  1986cites this paper
• Monoterpene cyclases: use of the noncyclizable substrate analog 6,7-dihydrogeranyl pyrophosphate to uncouple the isomerization step of the coupled isomerization-cyclization reaction.

  1986cites this paper
• The mechanism and regulation of dolichyl phosphate biosynthesis in rat liver.

  1986cites this paper
• Evidence for the ionization steps in monoterpene cyclization reactions using 2-fluorogeranyl and 2-fluorolinalyl pyrophosphates as substrates.

  1986cites this paper
• Ability of plant callus cultures to synthesize and accumulate lower terpenoids

  1986cites this paper
• Radiolabeled allylic isoprenoid pyrophosphates: Synthesis, purification, and determination of specific activity

  1986cites this paper
• Stereochemistry at C-1 of geranyl pyrophosphate and neryl pyrophosphate in the cyclization to (+)- and (-)-bornyl pyrophosphate.

  1985cites this paper
• Mechanism of the pyrophosphate migration in the enzymatic cyclization of geranyl and linalyl pyrophosphates to (+)- and (-)-bornyl pyrophosphates.

  1985cites this paper
• Biosynthesis of monoterpenes: demonstration of a geranyl pyrophosphate:(-)-bornyl pyrophosphate cyclase in soluble enzyme preparations from tansy (Tanacetum vulgare).

  1985cites this paper
• [44] Monoterpene and sesquiterpene cyclases

  1985cites this paper
• [45] Carbocyclases from Citrus limonum

  1985cites this paper
• Biosynthesis of monoterpenes. Enantioselectivity in the enzymatic cyclization of linalyl pyrophosphate to (-)-endo-fenchol.

  1985cites this paper
• Secondary Plant Substances. Monoterpenes

  1984cites this paper
• Cyclization of farnesyl pyrophosphate to the sesquiterpene olefins humulene and caryophyllene by an enzyme system from sage (Salvia officinalis).

  1984cites this paper
• Development and Essential Oil Content of Secretory Glands of Sage (Salvia officinalis).

  1984cites this paper
• Pinene cyclases I and II. Two enzymes from sage (Salvia officinalis) which catalyze stereospecific cyclizations of geranyl pyrophosphate to monoterpene olefins of opposite configuration.

  1984cites this paper
• Biosynthesis of Terpenoids in Glandular Trichomes

  1984cites this paper
• Metabolism of Monoterpenes : Early Steps in the Metabolism of d-Neomenthyl-beta-d-Glucoside in Peppermint (Mentha piperita) Rhizomes.

  1984cites this paper
• Monoterpene hydrocarbon biosynthesis by isolated leucoplasts of Citrofortunella mitis

  1983cites this paper
• Demonstration that limonene is the first cyclic intermediate in the biosynthesis of oxygenated p-menthane monoterpenes in Mentha piperita and other Mentha species.

  1983cites this paper
• Chapter 13 Terpenoids

  1983cites this paper
• Advances in the Chemistry of Some Interesting Cyclic Monoterpene Alcohols

  1982cites this paper
• Biosynthesis of (+/-)-alpha-pinene and (-)-beta-pinene from geranyl pyrophosphate by a soluble enzyme system from sage (Salvia officinalis).

  1982cites this paper
• Evidence that sabinene is an essential precursor of C(3)-oxygenated thujane monoterpenes.

  1982cites this paper
• Relationship of Camphor Biosynthesis to Leaf Development in Sage (Salvia officinalis).

  1981cites this paper
• Conversion of [1-3H2,G-14C]geranyl pyrophosphate to cyclic monoterpenes without loss of tritium.

  1981cites this paper
• Metabolism of Monoterpenes : EVIDENCE FOR COMPARTMENTATION OF l-MENTHONE METABOLISM IN PEPPERMINT (MENTHA PIPERITA) LEAVES.

  1981cites this paper
• Biosynthesis of monoterpenes: preliminary characterization of i-endo-fenchol synthetase from fennel (Foeniculum vulgare) and evidence that no free intermediate is involved in the cyclization of geranyl pyrophosphate to the rearranged product.

  1980cites this paper
• Substrate specificity of monoterpenol dehydrogenases from Foeniculum vulgare and Tanacetum vulgare

  1980cites this paper
• Biochemistry of Terpenoids

  1980cites this paper
• Studies on the biosynthesis of the carane skeleton

  1980cites this paper
• Biosynthesis of monoterpenes: conversion of the acyclic precursors geranyl pyrophosphate and neryl pyrophosphate to the rearranged monoterpenes fenchol and fenchone by a soluble enzyme preparation from fennel (Foeniculum vulgare).

  1980cites this paper
• The stereochemistry of allylic pyrophosphate metabolism

  1980cites this paper
• Biosynthesis of monoterpenes: hydrolysis of bornyl pyrophosphate, an essential step in camphor biosynthesis, and hydrolysis of geranyl pyrophosphate, the acyclic precursor of camphor, by enzymes from sage (Salvia officinalis).

  1979cites this paper
• Biosynthesis of monoterpenes: preliminary characterization of bornyl pyrophosphate synthetase from sage (Salvia officinalis) and demonstration that Geranyl pyrophosphate is the preferred substrate for cyclization.

  1979cites this paper
• Metabolism of Monoterpenes: Acetylation of (-)-Menthol by a Soluble Enzyme Preparation from Peppermint (Mentha piperita) Leaves.

  1978cites this paper
• gamma-Terpinene synthetase: a key enzyme in the biosynthesis of aromatic monoterpenes.

  1978cites this paper
• Biosynthesis of monoterpenes: Partial purification and characterization of a bicyclic monoterpenol dehydrogenase from sage (Salvia officinalis)☆

  1978cites this paper
• Biosynthesis of aromatic monoterpenes: Conversion of γ-terpinene to p-cymene and thymol in Thymus vulgaris L

  1978cites this paper
• BIOSYNTHESIS OF BENZALDEHYDE, BENZYL ALCOHOL AND BENZYL BENZOATE FROM BENZOIC ACID IN CRANBERRY (VACCINIUM MACROCARPON)

  1978cites this paper
• Biosynthesis of aromatic monoterpenes: conversion of gamma-terpinene to p-cymene and thymol in Thymus vulgaris L.

  1978cites this paper
• Site of Monoterpene Biosynthesis in Majorana hortensis Leaves.

  1977cites this paper
• Demonstration of a cyclic pyrophosphate intermediate in the enzymatic conversion of neryl pyrophosphate to borneol.

  1977cites this paper
• Biosynthesis of monoterpenes: partial purification and characterization of 1,8-cineole synthetase from Salvia officinalis.

  1977cites this paper