X-Chromosome Genetics and Human Cancer

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Nature Reviews. Cancer

• Publication date

  2004-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/nrc1413PMID 15286741
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Linking the epigenetic ‘language’ of covalent histone modifications to cancer

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• Epigenetic Dynamics of Imprinted X Inactivation During Early Mouse Development

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• Inheritance of a pre-inactivated paternal X chromosome in early mouse embryos

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• Identification and characterization of mouse SSX genes: a multigene family on the X chromosome with restricted cancer/testis expression.

  2003cited by this paper
• Comparative genomic hybridization analysis of hepatoblastoma reveals high frequency of X-chromosome gains and similarities between epithelial and stromal components.

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• PSF-TFE3 oncoprotein in papillary renal cell carcinoma inactivates TFE3 and p53 through cytoplasmic sequestration

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• The roles of supernumerical X chromosomes and XIST expression in testicular germ cell tumors.

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• Cytosine methylation mediates sexual conflict.

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• Malignancy‐associated allelic losses on the X‐chromosome in foregut but not in midgut endocrine tumours

  2002cited by this paper
• Confirmation of the prostate cancer susceptibility locus HPCX in a set of 104 German prostate cancer families

  2002cited by this paper
• Xist RNA and the mechanism of X chromosome inactivation.

  2002cited by this paper
• Unbalanced X;autosome translocations provide evidence for sequence specificity in the association of XIST RNA with chromatin.

  2002cited by this paper
• Lack of expression of XIST from a small ring X chromosome containing the XIST locus in a girl with short stature, facial dysmorphism and developmental delay

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• The XAGE family of cancer/testis‐associated genes: Alignment and expression profile in normal tissues, melanoma lesions and Ewing's sarcoma

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• Growth and Ovarian Function in Girls with 48,XXXX Karyotype - Patient Report and Review of the Literature

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• High frequency of skewed X inactivation in young breast cancer patients

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• Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes

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• Acquired gain of an X chromosome as the sole abnormality in the blast crisis of chronic neutrophilic leukemia.

  2002cited by this paper
• BRCA1 supports XIST RNA concentration on the inactive X chromosome.

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• Chromosomal silencing and localization are mediated by different domains of Xist RNA

  2002cited by this paper
• Gene expression profiles of BRCA1-linked, BRCA2-linked, and sporadic ovarian cancers.

  2002cited by this paper
• Incontinentia pigmenti: the first single gene disorder due to disrupted NF-kappa B function.

  2002cited by this paper
• Molecular and cytogenetic analysis of the spreading of X inactivation in X;autosome translocations.

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• Hypomethylated X Chromosome Gain and Rare Isochromosome 12p in Diverse Intracranial Germ Cell Tumors

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• A new member of the NY-ESO-1 gene family is ubiquitously expressed in somatic tissues and evolutionarily conserved.

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• Frequent loss Xq25 on the inactive X chromosome in primary breast carcinomas is associated with tumor grade and axillary lymph node metastasis

  2002cited by this paper
• Evidence of skewed X-chromosome inactivation in 47,XXY and 48,XXYY Klinefelter patients.

  2001cited by this paper
• Glypican-3 expression is silenced in human breast cancer

  2001cited by this paper
• Identification of novel deletion regions on chromosome arms 2q and 6p in breast carcinomas by amplotype analysis

  2001cited by this paper
• X chromosome-specific cDNA arrays: identification of genes that escape from X-inactivation and other applications.

  2001cited by this paper
• Expression of GPC3, an X-linked recessive overgrowth gene, is silenced in malignant mesothelioma

  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
• Sex-specific expression of gastrin-releasing peptide receptor: relationship to smoking history and risk of lung cancer.

  2000cited by this paper
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  2000cited by this paper
• Karyotypic findings in two cases of male breast cancer.

  2000cited by this paper
• Age- and tissue-specific variation of X chromosome inactivation ratios in normal women

  2000cited by this paper
• Promoter-specific hypoacetylation of X-inactivated genes.

  1999cited by this paper
• Association between nonrandom X-chromosome inactivation and BRCA1 mutation in germline DNA of patients with ovarian cancer.

  1999cited by this paper
• Pathogenesis of testicular germ cell tumours.

  1999cited by this paper
• DNA Methylation Is the Primary Silencing Mechanism for a Set of Germ Line- and Tumor-Specific Genes with a CpG-Rich Promoter

  1999cited by this paper
• RESPONSE: Re: Association Between Nonrandom X-Chromosome Inactivation and BRCA1 Mutation in Germline DNA of Patients With Ovarian Cancer.

  1999cited by this paper
• Androgen receptor gene alterations and chromosomal gains and losses in prostate carcinomas appearing during finasteride treatment for benign prostatic hyperplasia.

  1999cited by this paper
• A first-generation X-inactivation profile of the human X chromosome.

  1999cited by this paper
• Acquired X-chromosome aneuploidy in children with acute lymphoblastic leukemia.

  1999cited by this paper
• R esponse : Re: Association Between Nonrandom X-ChromosomeInactivation and BRCA1 Mutation in Germline DNA of Patients With OvarianCancer

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• Frequent silencing of the GPC3 gene in ovarian cancer cell lines.

  1999cited by this paper
• The DNA methylation paradox.

  1999cited by this paper
• Characterization of the GAGE genes that are expressed in various human cancers and in normal testis.

  1999cited by this paper
• Gastric neuroendocrine neoplasms: tumour clonality and malignancy‐associated large X‐chromosomal deletions

  1999cited by this paper
• X-linked Wiskott-Aldrich syndrome in a girl.

  1998cited by this paper
• Evidence for a prostate cancer susceptibility locus on the X chromosome.

  1998cited by this paper
• A one centimorgan deletion unit on chromosome Xq12 is commonly lost in borderline and invasive epithelial ovarian tumors

  1998cited by this paper
• Chromosomal imbalances in papillary renal cell carcinoma: genetic differences between histological subtypes.

  1998cited by this paper
• The spreading of X inactivation into autosomal material of an x;autosome translocation: evidence for a difference between autosomal and X-chromosomal DNA.

  1998cited by this paper
• Bilateral retinoblastoma in a male patient with an X; 13 translocation: evidence for silencing of the RB1 gene by the spreading of X inactivation.

  1997cited by this paper
• Loss of heterozygosity at chromosome segment Xq25‐26.1 in advanced human ovarian carcinomas

  1997cited by this paper
• A promoter mutation in the XIST gene in two unrelated families with skewed X-chromosome inactivation

  1997cited by this paper
• X inactivation in human testicular tumors. XIST expression and androgen receptor methylation status.

  1997cited by this paper
• Analysis of loss of heterozygosity and KRAS2 mutations in ovarian neoplasms: Clinicopathological correlations

  1997cited by this paper
• Selection against mutant alleles in blood leukocytes is a consistent feature in Incontinentia Pigmenti type 2.

  1996cited by this paper
• Potential role of the inactivated X chromosome in ovarian epithelial tumor development.

  1996cited by this paper
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  1996cited by this paper
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  1995cited by this paper
• Evidence of an X-linked or recessive genetic component to prostate cancer risk

  1995cited by this paper
• Analysis of genetic changes underlying local recurrence of prostate carcinoma during androgen deprivation therapy.

  1995cited by this paper
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  1994cited by this paper
• Comparison of loss of heterozygosity patterns in invasive low-grade and high-grade epithelial ovarian carcinomas.

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  1992cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1991cited by this paper
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  1991cited by this paper
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  1991cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1988cited by this paper
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  1987cited by this paper
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  1980cited by this paper
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  1979cited by this paper
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  1979cited by this paper
• Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

  1961cited by this paper
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  1957cited by this paper
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  1956cited by this paper
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• FHL1 as a prognostic biomarker and therapeutic target in acute promyelocytic leukaemia

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• GXwasR: A Toolkit for Investigating Sex-Differentiated Genetic Effects on Complex Traits

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