Effect of acidic reperfusion on prolongation of intracellular acidosis and myocardial salvage.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Cardiovascular Research

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  DOI 10.1093/CVR/CVM082PMID 18056767
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Clinical applicability of preconditioning and postconditioning: the cardiothoracic surgeons's view.

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• Ischemic preconditioning prevents calpain-mediated impairment of Na+/K+-ATPase activity during early reperfusion.

  2006influential reference
• Postconditioning: reperfusion of "reperfusion injury" after hibernation.

  2006cited by this paper
• Mechanisms, management and future directions for reperfusion injury after acute myocardial infarction

  2005cited by this paper
• Postconditioning the Human Heart

  2005cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
• Effect of inhibition of Na(+)/Ca(2+) exchanger at the time of myocardial reperfusion on hypercontracture and cell death.

  2002cited by this paper
• Importance of bicarbonate transport for protection of cardiomyocytes against reoxygenation injury.

  2000cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1997cited by this paper
• Effects of acidic reperfusion on arrhythmias and Na(+)-K(+)-ATPase activity in regionally ischemic rat hearts.

  1996cited by this paper
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  1996cited by this paper
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  1995cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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• Effects of changes of pH on the contractile function of cardiac muscle.

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• Effect of acidosis and alkalosis on postischemic Ca gain in isolated rat heart.

  1990cited by this paper
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  1988cited by this paper
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  1978cited by this paper
• Determination of intracellular pH by 31P magnetic resonance.

  1973cited by this paper

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