The role of the nervous system in rhinitis.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of Allergy and Clinical Immunology

• Publication date

  2006-11-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/J.JACI.2006.09.013PMID 17088122
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The effect of trigeminal resection on reflex bronchoconstriction after nasal and nasopharyngeal irritation in man.

  2015cited by this paper
• A New Strategy for the Treatment of Inflammatory Pain

  2012cited by this paper
• Neurotrophins in allergic diseases: from neuronal growth factors to intercellular signaling molecules.

  2006cited by this paper
• Extending the understanding of sensory neuropeptides.

  2006cited by this paper
• Cysteinyl leukotrienes: multi-functional mediators in allergic rhinitis

  2006cited by this paper
• Neurotrophins and asthma: novel insight into neuroimmune interaction.

  2006cited by this paper
• Objective monitoring of nasal patency and nasal physiology in rhinitis

  2005cited by this paper
• Neurotrophin overexpression in lower airways of infants with respiratory syncytial virus infection.

  2005cited by this paper
• Extracellular Cations Sensitize and Gate Capsaicin Receptor TRPV1 Modulating Pain Signaling

  2005cited by this paper
• Secretoneurin: a new player in angiogenesis and chemotaxis linking nerves, blood vessels and the immune system.

  2005cited by this paper
• Secretoneurin is released into human airways by topical histamine but not capsaicin

  2005cited by this paper
• Allergen-induced substance P synthesis in large-diameter sensory neurons innervating the lungs.

  2005cited by this paper
• Nasal sensory nerve populations responding to histamine and capsaicin.

  2005cited by this paper
• Phenotypic alteration of neuropeptide‐containing nerve fibres in seasonal intermittent allergic rhinitis

  2004cited by this paper
• Effects of intranasal capsaicin challenge on cough reflex in healthy human volunteers.

  2004cited by this paper
• Evidence, Mechanisms, and Clinical Implications of Central Hypersensitivity in Chronic Pain After Whiplash Injury

  2004cited by this paper
• Seasonal variation of sensitivity of nasal mucosa in pollinosis

  2004cited by this paper
• The secretory activity of rat nasal glands and the effect of cholinergic drugs

  2004cited by this paper
• Effect of eosinophil adhesion on intracellular signaling in cholinergic nerve cells.

  2004cited by this paper
• Thresholds in Nasal Histamine Challenge in Patients with Allergic Rhinitis, Patients with Hyperreflectory Rhinopathy, and Healthy Volunteers

  2004cited by this paper
• Abeta-fiber nociceptive primary afferent neurons: a review of incidence and properties in relation to other afferent A-fiber neurons in mammals.

  2004cited by this paper
• Expression of neurokinin a receptor mRNA in human nasal mucosa

  2004cited by this paper
• Modulation of experimentally-induced cough by stimulation of nasal mucosa in cats and guinea pigs.

  2004cited by this paper
• Beneficial effects of intranasal applications of capsaicin in patients with vasomotor rhinitis

  2004cited by this paper
• The diagnosis and management of chronic cough

  2004cited by this paper
• The diagnosis and management of chronic cough.

  2004cited by this paper
• The role of substance P in inflammatory disease

  2004cited by this paper
• Elevated substance P levels in nasal lavage fluids from patients with chronic nonproductive cough and increased cough sensitivity to inhaled capsaicin.

  2003cited by this paper
• Adrenergic mechanisms in canine nasal venous systems

  2003cited by this paper
• Neural expression and increased lavage fluid levels of secretoneurin in seasonal allergic rhinitis.

  2003cited by this paper
• Upper and lower respiratory disease

  2003cited by this paper
• Localization of nerve growth factor and its receptors in the human nasal mucosa.

  2003cited by this paper
• Montelukast improves symptoms of seasonal allergic rhinitis over a 4‐week treatment period

  2003cited by this paper
• Rhinitis and asthma: evidence for respiratory system integration.

  2003cited by this paper
• Intranasal capsaicin reduces nasal hyperreactivity in idiopathic rhinitis: a double‐blind randomized application regimen study

  2003cited by this paper
• Human eosinophils produce neurotrophins and secrete nerve growth factor on immunologic stimuli.

  2002cited by this paper
• Allergic inflammation-induced neuropeptide production in rapidly adapting afferent nerves in guinea pig airways.

  2002cited by this paper
• Immunohistochemical Localization of Subtypes of Muscarinic Receptors in Human Inferior Turbinate Mucosa

  2002cited by this paper
• Acute topical application of tumor necrosis factor alpha evokes protein kinase A-dependent responses in rat sensory neurons.

  2002cited by this paper
• Upper airway neurogenic mechanisms

  2002cited by this paper
• Pathophysiological mechanisms for the respiratory syncytial virus-reactive airway disease link

  2002cited by this paper
• Lack of evidence for muscarinic type 2 receptor modulation of the human nasonasal reflex.

  2001cited by this paper
• Sympathetic control of nasal blood flow in the rat mediated by α1-adrenoceptors

  2001cited by this paper
• The role of sensory nerve endings in nerve growth factor‐induced airway hyperresponsiveness to histamine in guinea‐pigs

  2001cited by this paper
• Update on nonallergic rhinitis.

  2001cited by this paper
• Sympathetic control of nasal blood flow in the rat mediated by alpha(1)-adrenoceptors.

  2001cited by this paper
• Nerve growth factor expression and release in allergic inflammatory disease of the upper airways.

  2000cited by this paper
• Nasobronchial relationship after cold air provocation.

  2000cited by this paper
• Neural integration and allergic disease.

  2000cited by this paper
• Nerve growth factor-induced phenotypic switch in guinea pig airway sensory neurons.

  2000cited by this paper
• Antigen inhalation unmasks NK-2 tachykinin receptor-mediated responses in vagal afferents.

  2000cited by this paper
• Role of Vascular Reflex in Nasal Mucosal Swelling in Nasal Allergy

  2000cited by this paper
• Autonomic Nervous System Evaluation of Patients With Vasomotor Rhinitis

  2000cited by this paper
• IgE receptor‐mediated release of nerve growth factor by mast cells

  2000cited by this paper
• Muscarinic receptor dysfunction in asthma

  2000cited by this paper
• Hypertonic saline nasal provocation stimulates nociceptive nerves, substance P release, and glandular mucous exocytosis in normal humans.

  1999cited by this paper
• Functional effects of neuropeptide Y receptors on blood flow and nitric oxide levels in the human nose.

  1999cited by this paper
• Hyperosmolar saline induces reflex nasal secretions, evincing neural hyperresponsiveness in allergic rhinitis.

  1999cited by this paper
• Decreased neuropeptide release may play a role in the pathogenesis of nasal polyps.

  1999cited by this paper
• Neural Hyperresponsiveness and Nerve Growth Factor in Allergic Rhinitis

  1999cited by this paper
• Neuro‐immune interactions in the lung

  1999cited by this paper
• Hyperinnervation of the airways in transgenic mice overexpressing nerve growth factor.

  1998cited by this paper
• Inhibition of 5-lipoxygenase diminishes neurally evoked tachykinergic contraction of guinea pig isolated airway.

  1998cited by this paper
• Neuropeptide innervation and neuroendocrine cells in allergic rhinitis and chronic hypertrophic rhinitis

  1998cited by this paper
• The long‐term effects of capsaicin aqueous spray on the nasal mucosa

  1998cited by this paper
• Subjects with seasonal allergic rhinitis and nonrhinitic subjects react differentially to nasal provocation with chlorine gas.

  1998cited by this paper
• Expression of substance P (NK1) receptor mRNA in human nose.

  1998cited by this paper
• Contribution of nitric oxide and sensory transmitters to non-adrenergic, non-cholinergic innervation of nasal blood vessels.

  1998cited by this paper
• Nerve growth factor is preformed in and activates human peripheral blood eosinophils.

  1998cited by this paper
• Intranasal cold dry air is superior to histamine challenge in determining the presence and degree of nasal hyperreactivity in nonallergic noninfectious perennial rhinitis.

  1998cited by this paper
• Comparison of nasal mucosal responsiveness to neuronal stimulation in non‐allergic and allergic rhinitis: effects of capsaicin nasal challenge

  1998cited by this paper
• Plasma extravasation through neuronal stimulation in human nasal mucosa in the setting of allergic rhinitis.

  1998cited by this paper
• Nitric oxide and parasympathetic vascular and secretory control of the dog nasal mucosa.

  1998cited by this paper
• Distribution and quantity of neuroendocrine markers in allergic rhinitis.

  1998cited by this paper
• Allergic Inflammation in Isolated Vagal Sensory Ganglia Unmasks Silent NK-2 Tachykinin Receptors

  1997cited by this paper
• Nasal eupnoeic inhalation of cold, dry air increases airway resistance in asthmatic patients.

  1997cited by this paper
• The capsaicin receptor: a heat-activated ion channel in the pain pathway

  1997cited by this paper
• Pretreatment with antibody to eosinophil major basic protein prevents hyperresponsiveness by protecting neuronal M2 muscarinic receptors in antigen-challenged guinea pigs.

  1997cited by this paper
• Intranasal capsaicin is efficacious in non‐allergic, non‐infectious perennial rhinitis. A placebo‐controlled study

  1997cited by this paper
• Sympathetic and parasympathetic interaction in vascular and secretory control of the nasal mucosa in anaesthetized dogs

  1997cited by this paper
• Neuropeptide Y Y1 receptor mechanisms in sympathetic vascular control.

  1997cited by this paper
• Dose-dependent effects of capsaicin nasal challenge: in vivo evidence of human airway neurogenic inflammation.

  1997cited by this paper
• Distribution and origin of nitric oxide synthase-containing nerve fibers in human nasal mucosa.

  1997cited by this paper
• Human mast cells express functional TrkA and are a source of nerve growth factor

  1997cited by this paper
• Is IL-6 both a cytokine and a neurotrophic factor?

  1996cited by this paper
• The diving reflex in non-eosinophilic non-allergic rhinitis.

  1996cited by this paper
• The Effect of Neuropeptides on Vessel Tone and cAMP Production

  1996cited by this paper
• Changes in airway resistance induced by nasal inhalation of cold dry, dry, or moist air in normal individuals.

  1996cited by this paper
• Inflammatory cellular influx follows capsaicin nasal challenge.

  1996cited by this paper
• Involvement of Cytokines in Lipopolysaccharide-Induced Facilitation of CGRP Release from Capsaicin-Sensitive Nerves in the Trachea: Studies with Interleukin-1β and Tumor Necrosis Factor-α

  1996cited by this paper
• Evidence that enhanced nasal reactivity to bradykinin in patients with symptomatic allergy is mediated by neural reflexes.

  1996cited by this paper
• Induction of tachykinin gene and peptide expression in guinea pig nodose primary afferent neurons by allergic airway inflammation.

  1996cited by this paper
• Physiology of the neurotrophins.

  1996cited by this paper
• Immunomodulation of afferent neurons in guinea‐pig isolated airway.

  1996cited by this paper
• Plasticity of the afferent innervation of the airways.

  1995cited by this paper
• Facial cooling, but not nasal breathing of cold air, induces bronchoconstriction: a study in asthmatic and healthy subjects.

  1995cited by this paper
• C-Fos-like immunoreactivity in the cat brainstem evoked by sneeze-inducing air puff stimulation of the nasal mucosa.

  1995cited by this paper
• Exudative hyperresponsiveness of the airway microcirculation in seasonal allergic rhinitis

  1995cited by this paper
• NK1 receptors mediate leukocyte adhesion in neurogenic inflammation in the rat trachea.

  1995cited by this paper
• Selective recruitment of eosinophils by substance P after repeated allergen exposure in allergic rhinitis

  1995cited by this paper

• Allergic comorbidities in fibromyalgia.

  2025cites this paper
• Xiao-Qing-Long-Tang alleviates allergic rhinitis by inhibiting M1 macrophage polarization and modulating the TRPV1 channel.

  2025cites this paper
• Innovative surgical approaches for chronic rhinitis: nasal neurectomy mechanisms, techniques, and clinical outcomes

  2025cites this paper
• Cardiorespiratory benefits of reducing indoor particulate matter depend on immune improvements: Insights into individual heterogeneity from a randomized, double-blind crossover trial.

  2025cites this paper
• Touching a Nerve: Neuroimmune Interactions in Asthma

  2025cites this paper
• Unique compound with anti-allergic action: inhibition of Lyn kinase activity by KIRA6

  2025cites this paper
• Part II – imidazolines and rhinitis medicamentosa: how can we tackle the rebound dilemma?

  2025cites this paper
• Resting-state functional MRI of the nose as a novel investigational window into the nervous system

  2024cites this paper
• Nasal solitary chemosensory cells govern daily rhythm in mouse model of allergic rhinitis.

  2024cites this paper
• Endoscopic Vidian neurectomy for treating postcoital unilateral hydrorhinorrhea: A case report and literature review

  2024cites this paper
• The Role of Neuro-Immune Interactions in the Pathology and Pathogenesis of Allergic Rhinitis

  2024influential citation
• Acupuncture at "Die E acupoint" alleviates inflammatory reaction via inhibiting TLR4/MyD88/NF-κB signaling in rats with allergic rhinitis.

  2024cites this paper
• Expression of NMU and NMUR1 in tryptase-positive mast cells and PBLs in allergic rhinitis patients’ nasal mucosa

  2024cites this paper
• The role of nociceptive neurons in allergic rhinitis

  2024cites this paper
• Sphenopalatine ganglion stimulation: a comprehensive evaluation across diseases in randomized controlled trials

  2024cites this paper
• Assessing the Immediate Impact of High-Intensity Interval Exercise on Symptoms and Fractional Exhaled Nitric Oxide Levels

  2024cites this paper
• Effects of nasal allergens and environmental particulate matter on brainstem metabolites and the consequence of brain-spleen axis in allergic rhinitis.

  2024cites this paper
• Acupuncture for allergic rhinitis: protocol for a systematic review and network meta-analysis

  2024cites this paper
• Probing Relative Humidity Impact on Biological Protein Bovine Serum Albumin and Bovine Submaxillary Gland Mucin by Using Contact Resonance Atomic Force Microscopy

  2023cites this paper
• Acoustic resonance therapy is safe and effective for the treatment of nasal congestion in rhinitis: A randomized sham‐controlled trial

  2023cites this paper
• Endoscopic vidian and vidian‐branch neurectomy for refractory allergic rhinitis: A systematic review

  2023cites this paper
• Airway Transcriptome Networks Identify Susceptibility to Frequent Asthma Exacerbations in Children.

  2023cites this paper
• Effect of topical anticholinergic medication on clinical manifestations control among patients with vasomotor rhinitis versus allergic rhinitis: as comparative clinical trials

  2023cites this paper
• The Effect of Nasal-Sinus Comorbidities to Patients with Chronic Obstructive Pulmonary Disease

  2022cites this paper
• Adhesion Promotes Allergic Rhinitis CD4+IL4+ T Cell Differentiation via ICAM1 and E-Selectin

  2022cites this paper
• Brain response in allergic rhinitis: Profile and proposal

  2022cites this paper
• Allergic Rhinitis: keys for the clinician

  2022cites this paper
• Autonomic nervous system dysfunction and the effect of vitamin D level in vasomotor rhinitis patients

  2022cites this paper
• Temperature‐controlled radiofrequency neurolysis for treatment of chronic rhinitis: 12‐month outcomes after treatment in a randomized controlled trial

  2022cites this paper
• Regulation of breathing by cardiopulmonary afferents.

  2022cites this paper
• Acupuncture and its effect on cytokine and chemokine profiles in seasonal allergic rhinitis: a preliminary three-armed, randomized, controlled trial

  2022cites this paper
• Exploring the Mechanism of Yiqi Qingre Ziyin Method in Regulating Neuropeptide Expression for the Treatment of Atrophic Rhinitis

  2022cites this paper
• Synaptic transmission molecules and their role in the pathogenesis of allergic rhinitis

  2022cites this paper
• Temperature Profile of Nasal Breathing for Respiration Monitoring in Ambulatory Settings

  2022cites this paper
• Clinical Results of Kinetic Oscillation Stimulation (K.O.S.) in Non-Allergic Rhinitis

  2022cites this paper
• Genetics and Epigenetics in Allergic Rhinitis

  2021cites this paper
• Increased Heart Rate Variability Response Among Infants with Reported Rhinorrhea and Watery Eyes: A Pilot Study

  2021cites this paper
• Latent Myofascial Trigger Points Injection Reduced the Severity of Persistent, Moderate to Severe Allergic Rhinitis: A Randomized Controlled Trial

  2021cites this paper
• Turkish Guideline for Diagnosis and Treatment of Allergic Rhinitis (ART)

  2021cites this paper
• Nasal Physiology and Sinusitis

  2021cites this paper
• Pathophysiology and management of gustatory rhinitis

  2021cites this paper
• Can Sex Improve Nasal Function?—An Exploration of the Link Between Sex and Nasal Function

  2021cites this paper
• A TRiP Through the Roles of Transient Receptor Potential Cation Channels in Type 2 Upper Airway Inflammation

  2021cites this paper
• Protective role of lycopene in experımental allergic rhinitis in rats.

  2021cites this paper
• Resonant vibration of the sinonasal cavities for the treatment of nasal congestion

  2021cites this paper
• Cholinergic neuron‐like D‐U87 cells promote polarization of allergic rhinitis T‐helper 2 cells

  2020cites this paper
• This familiar diagnosis of “rhinitis”

  2020cites this paper
• Этот привычный диагноз «ринит»

  2020cites this paper
• The effect of drugs used in allergic rhinitis on the central nervous system

  2020cites this paper
• Zonula occludens and nasal epithelial barrier integrity in allergic rhinitis

  2020cites this paper
• Bencycloquidium bromide nasal spray is effective and safe for persistent allergic rhinitis: a phase III, multicenter, randomized, double-blinded, placebo-controlled clinical trial

  2020cites this paper
• Nasal Allergen Challenge and Environmental Exposure Chamber Challenge: A Randomized Trial Comparing Clinical and Biological Responses to Cat Allergen.

  2020cites this paper
• Efficacy of Acupuncture at the Sphenopalatine Ganglion in the Treatment of Persistent Allergic Rhinitis

  2020influential citation
• Non-Reflex Defense Mechanisms of Upper Airway Mucosa: Possible Clinical Application.

  2020cites this paper
• A Precision Medicine Approach to Rhinitis Evaluation and Management

  2020cites this paper
• Allergic rhinitis

  2020cites this paper
• Fibromyalgia in the Patients With Allergic Rhinitis: Its Prevalence and Impact on the Quality of Life

  2019cites this paper
• Chemical Intolerance in Patients With Nasal Inflammatory Disorders Using QEESIⓒ

  2019cites this paper
• Update on the pathophysiology and treatment of rhinogenic headache: focus on the ibuprofen/pseudoephedrine combination

  2019cites this paper
• Differentiation of human glioblastoma U87 cells into cholinergic neuron.

  2019cites this paper
• Allergic and Mixed Rhinitis: Diagnosis and Natural Evolution

  2019cites this paper
• Increased salivary fluid flow in children with newly diagnosed allergic rhinitis.

  2019cites this paper
• A Novel Approach for Investigating Upper Airway Hyperresponsiveness Using Micro-CT in Eosinophilic Upper Airway Inflammation such as Allergic Rhinitis Model

  2019cites this paper
• Neuropathic Pain and Itch Mechanisms Underlying Allergic Conjunctivitis.

  2019cites this paper
• The role of nasal cytology in the diagnosis of allergic and non-allergic rhinitis in adult and children.

  2019cites this paper
• Principles of Urgent Management of Acute Airway Obstruction.

  2018cites this paper
• Treatment of persistent allergic rhinitis via acupuncture at the sphenopalatine acupoint: a randomized controlled trial

  2018cites this paper
• Allergic Rhinitis in Rats Is Associated with an Inflammatory Response of the Hippocampus

  2018cites this paper
• Catgut Implantation at Acupoint Reduces Immune Reaction in a Rat Model of Allergic Rhinitis

  2018cites this paper
• Autonomic nervous system dysfunction and sinonasal symptoms

  2018influential citation
• 5 Imaging Rhinosinusitis

  2018cites this paper
• General illness and psychological factors in patients with chronic nasal symptoms

  2018cites this paper
• Effect of Nasal Continuous Positive Pressure on the Nostrils of Patients with Sleep Apnea Syndrome and no Previous Nasal Pathology . Predictive Factors for Compliance

  2018cites this paper
• The inferior turbinate: An autonomic organ.

  2018cites this paper
• Microbiota Composition and the Integration of Exogenous and Endogenous Signals in Reactive Nasal Inflammation

  2018cites this paper
• Manifestations of Inhalant Allergies Beyond the Nose.

  2017cites this paper
• A Pilot Study Investigating Clinical Responses and Biological Pathways of Azelastine/Fluticasone in Nonallergic Vasomotor Rhinitis before and after Cold Dry Air Provocation

  2017cites this paper
• Follow Your Nose-A Lesson in Pathogenesis and Pathophysiology

  2017cites this paper
• The nose and sinuses in COPD

  2017cites this paper
• Kinetic oscillatory stimulation of nasal mucosa in non-allergic rhinitis: comparison of patient self-administration and caregiver administration regarding pain and treatment effect. A randomized clinical trial

  2017cites this paper
• Valoración del efecto de la presión positiva continua nasal en las fosas nasales de pacientes, alérgicos y no alérgicos, con síndrome de apnea del sueño. Estudio de factores pronósticos de cumplimiento

  2017cites this paper
• Pathophysiology of IL-33 and IL-17 in allergic disorders.

  2017cites this paper
• Gr upSM Upper Airway Cough Syndrome – Definition , Pathogenesis and Clinical Significance

  2017cites this paper
• Allergic Rhinitis and Migraine Headache

  2017cites this paper
• Strontium chloride hexahydrate as a candidate molecule for long-term treatment of allergic rhinitis

  2017cites this paper
• Histamine and T helper cytokine–driven epithelial barrier dysfunction in allergic rhinitis

  2017cites this paper
• Structural and functional role of CADM1 on mast cell-neuron cross-talk

  2016cites this paper
• Denervation of nasal mucosa induced by posterior nasal neurectomy suppresses nasal secretion, not hypersensitivity, in an allergic rhinitis rat model

  2016cites this paper
• Face and neck: airway and sensorial capacities.

  2016cites this paper
• Dynamic Changes in Heart Rate Variability and Nasal Airflow Resistance during Nasal Allergen Provocation Test

  2016cites this paper
• Imetit Dihydrobromide and Thioperamide Medication in Cough Hypersensitivity Model—The Role of H3 Receptors

  2016cites this paper
• Effect of Nasal Continuous Positive Pressure on the Nostrils of Patients with Sleep Apnea Syndrome and no Previous Nasal Pathology. Predictive Factors for Compliance.

  2016cites this paper
• Prostaglandin D2 Modulates Neuronal Excitation of the Trigeminal Ganglion to Augment Allergic Rhinitis in Guinea Pigs

  2016cites this paper
• Rhinitis Subtypes, Endotypes, and Definitions

  2016cites this paper
• Increased expression of bitter taste receptors in human allergic nasal mucosa and their contribution to the shrinkage of human nasal mucosa

  2016cites this paper
• Nonallergic Rhinitis: Environmental Determinants.

  2016cites this paper
• Non-Allergic Rhinitis

  2016cites this paper
• Sphenopalatine Ganglion Acupuncture Improves Nasal Ventilation and Modulates Autonomic Nervous Activity in Healthy Volunteers: A Randomized Controlled Study

  2016cites this paper
• Topical Application of TAT-Superoxide Dismutase in Acupoints LI 20 on Allergic Rhinitis

  2016cites this paper
• Pathogenesis of rhinitis

  2016cites this paper