Global analysis of the Bacillus subtilis Fur regulon and the iron starvation stimulon

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Molecular Microbiology

• Publication date

  2002-09-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1046/j.1365-2958.2002.03113.xPMID 12354229
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Regulation of ferric iron transport in Escherichia coli K12: Isolation of a constitutive mutant

  2004cited by this paper
• On specificity

  2003influential reference
• Recognition of DNA by Fur: a Reinterpretation of the Fur Box Consensus Sequence

  2002influential reference
• Metal Ion Uptake and Oxidative Stress

  2002cited by this paper
• Regulation of the Bacillus subtilis fur and perR Genes by PerR: Not All Members of the PerR Regulon Are Peroxide Inducible

  2002cited by this paper
• The Helicobacter pylori Homologue of the Ferric Uptake Regulator Is Involved in Acid Resistance

  2002cited by this paper
• A peroxide‐induced zinc uptake system plays an important role in protection against oxidative stress in Bacillus subtilis

  2002cited by this paper
• High-Salinity-Induced Iron Limitation in Bacillus subtilis

  2002cited by this paper
• A small RNA regulates the expression of genes involved in iron metabolism in Escherichia coli

  2002cited by this paper
• The dhb Operon of Bacillus subtilisEncodes the Biosynthetic Template for the Catecholic Siderophore 2,3-Dihydroxybenzoate-Glycine-Threonine Trimeric Ester Bacillibactin*

  2001cited by this paper
• The iron-regulated isiA gene of Fischerella muscicola strain PCC 73103 is linked to a likewise regulated gene encoding a Pcb-like chlorophyll-binding protein.

  2001cited by this paper
• Escherichia coli acid resistance: cAMP receptor protein and a 20 bp cis-acting sequence control pH and stationary phase expression of the gadA and gadBC glutamate decarboxylase genes.

  2001cited by this paper
• The Fur repressor controls transcription of iron‐activated and ‐repressed genes in Helicobacter pylori

  2001cited by this paper
• Comparative analysis of FUR regulons in gamma-proteobacteria.

  2001cited by this paper
• Roles of metal ions and hydrogen peroxide in modulating the interaction of the Bacillus subtilis PerR peroxide regulon repressor with operator DNA

  2001cited by this paper
• Molecular characterization of the ferric-uptake regulator, fur, from Staphylococcus aureus.

  2000cited by this paper
• Identification of Iron-Responsive, Differential Gene Expression in the Cyanobacterium Synechocystis sp. Strain PCC 6803 with a Customized Amplification Library

  2000influential reference
• Global Gene Expression Profiles of Bacillus subtilis Grown under Anaerobic Conditions

  2000cited by this paper
• Regulation of the lic Operon ofBacillus subtilis and Characterization of Potential Phosphorylation Sites of the LicR Regulator Protein by Site-Directed Mutagenesis

  1999cited by this paper
• Interaction of Bacillus subtilis Fur (Ferric Uptake Repressor) with the dhb Operator In Vitro and In Vivo

  1999influential reference
• Opening the Iron Box: Transcriptional Metalloregulation by the Fur Protein

  1999cited by this paper
• Identification and transcriptional analysis of new members of the sigmaB regulon in Bacillus subtilis.

  1999cited by this paper
• Bacillus subtilis aconitase is an RNA-binding protein.

  1999influential reference
• The ferric uptake regulator (Fur) homologue of Helicobacter pylori: functional analysis of the coding gene and controlled production of the recombinant protein in Escherichia coli

  1999cited by this paper
• Identification of Fur, Aconitase, and Other Proteins Expressed by Mycobacterium tuberculosis under Conditions of Low and High Concentrations of Iron by Combined Two-Dimensional Gel Electrophoresis and Mass Spectrometry

  1999cited by this paper
• Bacterial iron transport: mechanisms, genetics, and regulation.

  1998cited by this paper
• Identification of a Zinc-Specific Metalloregulatory Protein, Zur, Controlling Zinc Transport Operons inBacillus subtilis

  1998cited by this paper
• Nitrogen and Oxygen Regulation of Bacillus subtilis nasDEF Encoding NADH-Dependent Nitrite Reductase by TnrA and ResDE

  1998cited by this paper
• A chloride‐inducible acid resistance mechanism in Lactococcus lactis and its regulation

  1998cited by this paper
• Bacillus subtilis contains multiple Fur homologues: identification of the iron uptake (Fur) and peroxide regulon (PerR) repressors

  1998cited by this paper
• Characterization of the macrolide P-450 hydroxylase from Streptomyces venezuelae which converts narbomycin to picromycin.

  1998cited by this paper
• Binding of the fur (ferric uptake regulator) repressor of Escherichia coli to arrays of the GATAAT sequence.

  1998cited by this paper
• IroN, a Novel Outer Membrane Siderophore Receptor Characteristic of Salmonella enterica

  1998cited by this paper
• Regulation of the Salmonella typhimurium flavohemoglobin gene. A new pathway for bacterial gene expression in response to nitric oxide.

  1998cited by this paper
• Sequence and analysis of a 31 kb segment of the Bacillus subtilis chromosome in the area of the rrnH and rrnG operons.

  1997cited by this paper
• Transcriptional regulation of a second flavodoxin gene from Klebsiella pneumoniae.

  1997cited by this paper
• Duplicate isochorismate synthase genes of Bacillus subtilis: regulation and involvement in the biosyntheses of menaquinone and 2,3-dihydroxybenzoate

  1996influential reference
• Sequence and genetic organization of a Bacillus subtilis operon encoding 2,3-dihydroxybenzoate biosynthetic enzymes.

  1996cited by this paper
• A Permease-Oxidase Complex Involved in High-Affinity Iron Uptake in Yeast

  1996cited by this paper
• Coordinate regulation of Bacillus subtilis peroxide stress genes by hydrogen peroxide and metal ions.

  1995cited by this paper
• Compilation and analysis of Bacillus subtilis sigma A-dependent promoter sequences: evidence for extended contact between RNA polymerase and upstream promoter DNA

  1995cited by this paper
• Siderophores: Structure and Function of Microbial Iron Transport Compounds (*)

  1995cited by this paper
• Characterization of the Vibrio anguillarum fur gene: role in regulation of expression of the FatA outer membrane protein and catechols

  1994cited by this paper
• CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.

  1994cited by this paper
• The Bacillus subtilis sigma D-dependent operon encoding the flagellar proteins FliD, FliS, and FliT

  1994cited by this paper
• Microbial iron transport.

  1994cited by this paper
• Fur regulon in gram-negative bacteria. Identification and characterization of new iron-regulated Escherichia coli genes by a fur titration assay.

  1994cited by this paper
• Metalloregulation in Bacillus subtilis: isolation and characterization of two genes differentially repressed by metal ions

  1993influential reference
• Siderophores.

  1993cited by this paper
• Iron‐hydroxamate uptake systems in Bacillus subtilis: identification of a lipoprotein as part of a binding protein‐dependent transport system

  1993influential reference
• Mutations that relieve nutritional repression of the Bacillus subtilis dipeptide permease operon

  1993influential reference
• Iron specificity of the Fur-dependent regulation of the biosynthesis of the manganese-containing superoxide dismutase in Escherichia coli.

  1993cited by this paper
• A binding protein-dependent transport system in Streptococcus mutans responsible for multiple sugar metabolism.

  1992cited by this paper
• Sequence logos: a new way to display consensus sequences.

  1990cited by this paper
• Metal ion regulation of gene expression. Fur repressor-operator interaction at the promoter region of the aerobactin system of pColV-K30.

  1988cited by this paper
• Operator sequences of the aerobactin operon of plasmid ColV-K30 binding the ferric uptake regulation (fur) repressor

  1987cited by this paper
• Role of AbrB in Spo0A- and Spo0B-dependent utilization of a sporulation promoter in Bacillus subtilis

  1987influential reference
• Ferric uptake regulation protein acts as a repressor, employing iron (II) as a cofactor to bind the operator of an iron transport operon in Escherichia coli.

  1987cited by this paper
• On the specificity of DNA-protein interactions.

  1986cited by this paper
• Free radicals, lipid peroxidation, and cell damage.

  1984cited by this paper
• Constitutive expression of the iron-enterochelin and ferrichrome uptake systems in a mutant strain of Salmonella typhimurium

  1978cited by this paper
• POTENTIAL PITFALL IN BIOASSAY OF SERUM-GENTAMICIN

  1975cited by this paper
• Experiments in molecular genetics

  1972cited by this paper

• Siderophore-Dependent and -Independent Iron Acquisition Pathways in Marinobacter Nauticus SP17.

  2025cites this paper
• Inactivation of branched-chain amino acid uptake halts Staphylococcus aureus growth and induces bacterial quiescence within macrophages

  2025cites this paper
• Coproheme decarboxylase from Bacillus subtilis is required for bacterial growth and heme b biosynthesis under anaerobic conditions.

  2025cites this paper
• The iron chelator pulcherriminic acid mediates the light response in Bacillus subtilis biofilms

  2025cites this paper
• Siderophore-mediated iron acquisition by Klebsiella pneumoniae

  2024cites this paper
• PerR functions as a redox-sensing transcription factor regulating metal homeostasis in the thermoacidophilic archaeon Saccharolobus islandicus REY15A

  2024cites this paper
• Characterization of the dual regulation by a c-di-GMP riboswitch Bc1 with a long expression platform from Bacillus thuringiensis

  2024cites this paper
• 8-OxoG-Dependent Regulation of Global Protein Responses Leads to Mutagenesis and Stress Survival in Bacillus subtilis

  2024cites this paper
• Unusual Relationship between Iron Deprivation and Organophosphate Hydrolase Expression

  2023cites this paper
• The tug-of-war on iron between plant and pathogen

  2023cites this paper
• Bacterial metabolism and susceptibility to cell wall-active antibiotics.

  2023cites this paper
• Pulcherrimin protects Bacillus subtilis against oxidative stress during biofilm development

  2023cites this paper
• Functional Diversity of Homologous Oxidoreductases—Tuning of Substrate Specificity by a FAD-Stacking Residue for Iron Acquisition and Flavodoxin Reduction

  2023cites this paper
• Control of iron homeostasis by a regulatory protein-protein interaction in Bacillus subtilis: The FurA (YlaN) acts as an antirepressor to the ferric uptake regulator Fur

  2023cites this paper
• The Mutation of the DNA-Binding Domain of Fur Protein Enhances the Pathogenicity of Edwardsiella piscicida via Inducing Overpowering Pyroptosis

  2023cites this paper
• Meddling with Metal Sensors: Fur-Family Proteins as Signaling Hubs

  2023cites this paper
• The Key Element Role of Metallophores in the Pathogenicity and Virulence of Staphylococcus aureus: A Review

  2022cites this paper
• Mixed Heavy Metals Stress Induces Global Iron Starvation as Revealed by System Level Multi-Omic Analyses

  2022influential citation
• Iron-responsive riboswitches.

  2022cites this paper
• The Burkholderia cenocepacia iron starvation σ factor, OrbS, possesses an on-board iron sensor

  2022cites this paper
• Recent Advances in the Siderophore Biology of Shewanella

  2022cites this paper
• Mixed heavy metal stress induces global iron starvation response

  2022influential citation
• Crystal structure and metal binding properties of the periplasmic iron component EfeM from Pseudomonas syringae EfeUOB/M iron-transport system

  2022cites this paper
• Direct Antibiotic Activity of Bacillibactin Broadens the Biocontrol Range of <named-content content-type='genus-species'>Bacillus amyloliquefaciens</named-content> MBI600

  2021cites this paper
• Characterisation of the Manganese Superoxide Dismutase of Enterococcus faecium.

  2021cites this paper
• Direct Antibiotic Activity of Bacillibactin Broadens the Biocontrol Range of Bacillus amyloliquefaciens MBI600

  2021cites this paper
• The involvement of PacIRA system of Stenotrophomonas maltophilia in the uptake of Pseudomonas aeruginosa pyochelin and intraspecies competition for iron acquisition.

  2021cites this paper
• Identification of genes involved in regulating MnSOD2 production and root colonization in Bacillus cereus 905

  2021cites this paper
• Comprehensive genomic analysis of Bacillus subtilis 9407 reveals its biocontrol potential against bacterial fruit blotch

  2021cites this paper
• Biochemical characterization of ferric uptake regulator (Fur) from Aliivibrio salmonicida. Mapping the DNA sequence specificity through binding studies and structural modelling

  2020cites this paper
• Interdependency of regulatory effects of iron and riboflavin in the foodborne pathogen Shigella flexneri determined by integral transcriptomics

  2020cites this paper
• Adaptive Mechanisms of the Model Photosynthetic Organisms, Cyanobacteria, to Iron Deficiency

  2020cites this paper
• IurV, Encoded by ORF VCA0231, Is Involved in the Regulation of Iron Uptake Genes in Vibrio cholerae

  2020cites this paper
• The functional identification of Dps in oxidative stress resistance and virulence of Riemerella anatipestifer CH-1 using a new unmarked gene deletion strategy.

  2020cites this paper
• A functional and structural study of three bacterial nucleic acid-interacting proteins. The story of a Ferric Uptake Regulator, an Oligoribonuclease and an ATP-dependent DNA ligase

  2020cites this paper
• Iron Acquisition by Bacterial Pathogens: Beyond Tris‐Catecholate Complexes

  2020cites this paper
• Multi-metal nutrient restriction and crosstalk in metallostasis systems in microbial pathogens.

  2020cites this paper
• Microbial Photosynthesis

  2020cites this paper
• Impact of high salinity and the compatible solute glycine betaine on gene expression of Bacillus subtilis.

  2020cites this paper
• Bacillus subtilis Fur Is a Transcriptional Activator for the PerR-Repressed pfeT Gene, Encoding an Iron Efflux Pump

  2020cites this paper
• References

  2020cites this paper
• Dysregulation of Magnesium Transport Protects Bacillus subtilis against Manganese and Cobalt Intoxication

  2020cites this paper
• Double trouble: Bacillus depends on a functional Tat machinery to avoid severe oxidative stress and starvation upon entry into a NaCl-depleted environment.

  2020cites this paper
• Enhancing the production of poly-γ-glutamate in Bacillus subtilis ZJS18 by the heat- and osmotic shock and its mechanism

  2020cites this paper
• Microbial single-cell RNA sequencing by split-pool barcoding

  2019cites this paper
• Metabolic Remodeling during Biofilm Development of Bacillus subtilis

  2019influential citation
• Bacillus subtilis Regulators MntR and Zur Participate in Redox Cycling, Antibiotic Sensitivity, and Cell Wall Plasticity

  2019cites this paper
• Molecular crosstalk between plant beneficial rhizobacteria: identification of Pseudomonas compounds influencing the growth and antimicrobial potential of Bacillus velezensis

  2019cites this paper
• Heterogeneity in respiratory electron transfer and adaptive iron utilization in a bacterial biofilm

  2019cites this paper
• σI from Bacillus subtilis: Impact on Gene Expression and Characterization of σI-Dependent Transcription That Requires New Types of Promoters with Extended −35 and −10 Elements

  2018cites this paper
• The Role of the Glyoxylate Shunt in the Acclimation to Iron Limitation in Marine Heterotrophic Bacteria

  2018cites this paper
• Dissociation between Iron and Heme Biosyntheses Is Largely Accountable for Respiration Defects of Shewanella oneidensis fur Mutants

  2018cites this paper
• IdeR, a DtxR Family Iron Response Regulator, Controls Iron Homeostasis, Morphological Differentiation, Secondary Metabolism, and the Oxidative Stress Response in Streptomyces avermitilis

  2018cites this paper
• Genome-Wide Characterization of the Fur Regulatory Network Reveals a Link between Catechol Degradation and Bacillibactin Metabolism in Bacillus subtilis

  2018influential citation
• Overview on the Bacterial Iron-Riboflavin Metabolic Axis

  2018cites this paper
• Iron Deficiency Generates Oxidative Stress and Activation of the SOS Response in Caulobacter crescentus

  2018cites this paper
• Dissecting regulatory mechanisms of ComA-dependent and ComA-independent quorum sensing pathways in Bacillus subtilis

  2018cites this paper
• Genome-Wide Analysis of ResD, NsrR, and Fur Binding in Bacillus subtilis during Anaerobic Fermentative Growth by In Vivo Footprinting

  2017cites this paper
• Binding mode of metal ions to the bacterial iron import protein EfeO.

  2017cites this paper
• Redox Sensing by Fe2+ in Bacterial Fur Family Metalloregulators

  2017influential citation
• Pirated Siderophores Promote Sporulation in Bacillus subtilis

  2017cites this paper
• Sequential induction of Fur-regulated genes in response to iron limitation in Bacillus subtilis

  2017influential citation
• Ferrous iron efflux systems in bacteria.

  2017cites this paper
• Metal homeostasis and resistance in bacteria

  2017cites this paper
• The Role of Bacillithiol in Gram-Positive Firmicutes

  2017cites this paper
• Survival of non-sporulating Bacillus subtilis upon energy limitation

  2017cites this paper
• Copper and cerium-regulated gene expression in Methylosinus trichosporium OB3b

  2017cites this paper
• Ferric Uptake Regulator (FUR) protein: properties and implications in cyanobacteria

  2016cites this paper
• Genome-wide transcriptome profiling of nitrogen fixation in Paenibacillus sp. WLY78

  2016cites this paper
• Quaternary Structure of Fur Proteins, a New Subfamily of Tetrameric Proteins.

  2016cites this paper
• Novel small protein identification and quantitative proteomic analysis in Pseudomonas putida KT-­2440

  2016cites this paper
• Transcriptional Profiling Analysis of Bacillus subtilis in Response to High Levels of Fe3+

  2016cites this paper
• Characterization of a Novel Iron Acquisition Activity That Coordinates the Iron Response with Population Density under Iron-Replete Conditions in Bacillus subtilis

  2016cites this paper
• The MarR-like protein PchR (YvmB) regulates expression of genes involved in pulcherriminic acid biosynthesis and in the initiation of sporulation in Bacillus subtilis

  2016cites this paper
• The NEAT Domain-Containing Proteins of Clostridium perfringens Bind Heme

  2016cites this paper
• Intracellular Zn(II) Intoxication Leads to Dysregulation of the PerR Regulon Resulting in Heme Toxicity in Bacillus subtilis

  2016cites this paper
• Expanding the Role of FurA as Essential Global Regulator in Cyanobacteria

  2016cites this paper
• Molecular logic of the Zur-regulated zinc deprivation response in Bacillus subtilis

  2016cites this paper
• The Listeria monocytogenes Fur‐regulated virulence protein FrvA is an Fe(II) efflux P1B4‐type ATPase

  2016cites this paper
• Genome-wide identification of Bacillus subtilis Zur-binding sites associated with a Zur box expands its known regulatory network

  2015cites this paper
• Recent developments in understanding the iron acquisition strategies of gram positive pathogens.

  2015cites this paper
• Single asparagine to arginine mutation allows PerR to switch from PerR box to fur box.

  2015cites this paper
• Ferric Uptake Regulator Fur Control of Putative Iron Acquisition Systems in Clostridium difficile

  2015cites this paper
• Investigation of the determinants and biological consequences of phase variation of the fetA gene of Neisseria meningitides

  2015cites this paper
• Anabaena sp. Strain PCC 7120 Deficiency in the Cyanobacterium Characterization of the Response to Zinc

  2014cites this paper
• Structural and Mechanistic Basis of Zinc Regulation Across the E. coli Zur Regulon

  2014cites this paper
• α-fur, an antisense RNA gene to fur in the extreme acidophile Acidithiobacillus ferrooxidans.

  2014cites this paper
• Expression of Concern: Bacillus pumilus Reveals a Remarkably High Resistance to Hydrogen Peroxide Provoked Oxidative Stress

  2014cites this paper
• The FUR (ferric uptake regulator) superfamily: diversity and versatility of key transcriptional regulators.

  2014cites this paper
• Adaptation de Staphylococcus xylosus à la matrice carnée, impact des composés nitrosés et utilisation des sources de fer

  2014cites this paper
• Bacillus pumilus Reveals a Remarkably High Resistance to Hydrogen Peroxide Provoked Oxidative Stress

  2014cites this paper
• Small proteins can no longer be ignored.

  2014cites this paper
• Specificity of Metal Sensing: Iron and Manganese Homeostasis in Bacillus subtilis*

  2014cites this paper
• Regulation of Virulence by Iron in Gram-Positive Bacteria

  2013cites this paper
• Global transcriptional response of Caulobacter crescentus to iron availability

  2013cites this paper
• UvA-DARE ( Digital Academic Repository ) The general stress response of Bacillus subtilis

  2013cites this paper
• Anthrax and Iron

  2013cites this paper
• Mapping the twin‐arginine protein translocation network of Bacillus subtilis

  2013cites this paper
• Uptake of xenosiderophores in Bacillus subtilis occurs with high affinity and enhances the folding stabilities of substrate binding proteins

  2013cites this paper
• The general stress response of Bacillus subtilis

  2013cites this paper