Hyperhomocysteinemia and the risk for vascular disease in hemodialysis patients.

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Journal of the American Society of Nephrology

• Publication date

  1995-07-01

• Fields of study

  Medicine

• Identifiers
  PMID 7579064
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Carotid artery intimal-medial wall thickening and plasma homocyst(e)ine in asymptomatic adults. The Atherosclerosis Risk in Communities Study.

  1993cited by this paper
• Metabolic evidence that deficiencies of vitamin B-12 (cobalamin), folate, and vitamin B-6 occur commonly in elderly people.

  1993cited by this paper
• Hyperhomocysteinemia, a risk factor for atherosclerosis in chronic uremic patients.

  1993cited by this paper
• Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen.

  1993cited by this paper
• Homocysteine inhibits von Willebrand factor processing and secretion by preventing transport from the endoplasmic reticulum.

  1993cited by this paper
• The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine.

  1992cited by this paper
• Homocysteine and other sulfhydryl compounds enhance the binding of lipoprotein(a) to fibrin: a potential biochemical link between thrombosis, atherogenesis, and sulfhydryl compound metabolism.

  1992cited by this paper
• Neuropsychiatric consequences of cobalamin deficiency.

  1991cited by this paper
• Hyperhomocysteinemia: an independent risk factor for vascular disease.

  1991cited by this paper
• Homocysteine, an atherogenic stimulus, reduces protein C activation by arterial and venous endothelial cells.

  1990cited by this paper
• Plasma homocysteine, a risk factor for vascular disease: plasma levels in health, disease, and drug therapy.

  1989cited by this paper
• Ischemic Heart Disease in Chronic Renal Failure: Management Considerations

  1989cited by this paper
• Elevation of total homocysteine in the serum of patients with cobalamin or folate deficiency detected by capillary gas chromatography-mass spectrometry.

  1988cited by this paper
• Altered plasma free and protein-bound sulfur amino acid levels in patients undergoing maintenance hemodialysis.

  1987cited by this paper
• Oxidation of low-density lipoprotein by thiol compounds leads to its recognition by the acetyl LDL receptor.

  1987cited by this paper
• Homocysteine thiolactone, N-homocysteine thiolactonyl retinamide, and platelet aggregation.

  1987cited by this paper
• The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells.

  1987cited by this paper
• Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator.

  1986cited by this paper
• Peroxide mediated effects of homocysteine on arterial prostacyclin synthesis.

  1986cited by this paper
• Assay of methylmalonic acid in the serum of patients with cobalamin deficiency using capillary gas chromatography-mass spectrometry.

  1986cited by this paper
• The pathogenesis of atherosclerosis--an update.

  1986cited by this paper
• Pathogenesis of atherosclerosis.

  1985cited by this paper
• The natural history of homocystinuria due to cystathionine beta-synthase deficiency.

  1985cited by this paper
• Hyperlipidemia in renal failure: phenotypes and pathogenetic mechanisms.

  1984cited by this paper
• Do dialysis patients need extra folate?

  1983cited by this paper
• Plasma protein-bound homocyst(e)ine in patients requiring chronic haemodialysis.

  1983cited by this paper
• Effect of Homocysteine and Homocystine on Platelet and Vascular Arachidonic Acid Metabolism

  1982cited by this paper
• Accumulation of sulphur-containing amino acids including cysteine-homocysteine in patients on maintenance haemodialysis.

  1980cited by this paper
• Homocysteine-induced endothelial cell injury in vitro: a model for the study of vascular injury.

  1980cited by this paper
• Sulphur containing amino acids in chronic renal failure with particular reference to homocystine and cysteine‐homocysteine mixed disulphide

  1979cited by this paper
• Lipid abnormalities in maintenance dialysis patients and renal transplant recipients.

  1978cited by this paper
• Occlusive arterial disease in uraemic and haemodialysis patients and renal transplant recipients. A study of the incidence of arterial disease and of the prevalence of risk factors implicated in the pathogenesis of arteriosclerosis.

  1977cited by this paper
• Homocystine-induced arteriosclerosis. The role of endothelial cell injury and platelet response in its genesis.

  1976cited by this paper
• Studies on the nature and causes of hyperlipidaemia in uraemia, maintenance dialysis and renal transplantation.

  1975cited by this paper
• Accelerated atherosclerosis in prolonged maintenance hemodialysis.

  1974cited by this paper
• Production of arteriosclerosis by homocysteinemia.

  1970cited by this paper
• Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis.

  1969cited by this paper
• HOMOCYSTINURIA, AN ERROR IN THE METABOLISM OF METHIONINE.

  1964cited by this paper

• Research progress on the kidney-gut-brain axis in brain dysfunction in maintenance hemodialysis patients

  2025cites this paper
• Gut Microbiome, Functional Food, Atherosclerosis, and Vascular Calcifications—Is There a Missing Link?

  2021cites this paper
• Folic Acid and Vitamin B12 Administration in CKD, Why Not?

  2019cites this paper
• The Role of Homocysteine and Other Clinical Laboratory Markers in Assessing Cardiovascular Risk in Patients on Hemodialysis

  2016cites this paper
• extracellular matrix components in vascular cells Homocysteine redox receptor and regulation of

  2016cites this paper
• STAN NAWODNIENIA U CHORYCH PRZEWLEKLE HEMODIALIZOWANYCH A WYBRANE MARKERY RYZYKA SERCOWO-NACZYNIOWEGO

  2016cites this paper
• Maintenance of activities of daily living despite risk from genetic polymorphism in hemodialysis patients under nutritional management who survived an average of 30 years

  2015cites this paper
• Homocysteine and Hematological Indices in Hemodialysis Patients at Al-Shifa Hospital, Gaza Strip

  2013cites this paper
• Effects of Residual Renal Function on Left Ventricle and Analysis of Related Factors in Patients with Hemodialysis

  2013cites this paper
• MTHFR C677T and A1298C Gene Polymorphisms, Hyper- homocysteinemia, and Intimal Medial Thickness as Risk Factors of End-Stage Renal Disease in Children on Hemodialysis

  2012cites this paper
• Vaskuläre und parenchymatöse Nierenkrankheiten

  2012cites this paper
• Role of homocysteine in end-stage renal disease.

  2012cites this paper
• Pre-transplant cardiac evaluation and management of diabetic kidney disease patients before transplant

  2012cites this paper
• Micronutrient Metabolism in Hemodialysis Patients

  2011cites this paper
• The content of docosahexaenoic acid in serum phospholipid is inversely correlated with plasma homocysteine levels in patients with end-stage renal disease.

  2010cites this paper
• Homocysteine as a risk factor for cardiovascular disease in patients treated by dialysis: a meta-analysis.

  2009cites this paper
• A review of risk factors for stroke in patients with chronic kidney disease.

  2009cites this paper
• Recent progress in the analysis of uremic toxins by mass spectrometry.

  2009cites this paper
• Hypoalbuminemia and not hyperhomocysteinemia as a risk factor for dementia in hemodialysis patients.

  2008cites this paper
• Predictive Factors of Cardiovascular Disease in Patients on Maintenance Hemodialysis

  2008cites this paper
• La neurostimolazione midollare nel trattamento dell'ischemia critica non rivascolarizzabile del paziente uremico

  2008cites this paper
• Low total plasma homocysteine level in relation to malnutrition, inflammation, and outcome in hemodialysis patients.

  2008cites this paper
• CARDIOVASCULAR AND SURVIVAL PARADOXES IN DIALYSIS PATIENTS: Homocysteine‐Lowering Is Not a Primary Target for Cardiovascular Disease Prevention in Chronic Kidney Disease Patients

  2007cites this paper
• CARDIOVASCULAR AND SURVIVAL PARADOXES IN DIALYSIS PATIENTS: Is There a Reversal of Reverse Epidemiology in Renal Transplant Recipients?

  2007cites this paper
• MTHFR A1298C polymorphism is associated with cardiovascular risk in end stage renal disease in North Indians

  2007cites this paper
• Cardiorenal intersection: crossroads to the future.

  2007cites this paper
• Platelet phospholipid n-3 PUFA negatively associated with plasma homocysteine in middle-aged and geriatric hyperlipaemia patients.

  2007cites this paper
• Bestimmung arterieller Gefäßeigenschaften mittels nichtinvasiver Gefäßmessung bei Patienten mit chronischer Niereninsuffizienz Stadium 5

  2007cites this paper
• Novel and traditional cardiovascular risk factors for peripheral arterial disease in incident-dialysis patients.

  2007cites this paper
• [Evidence based hemodialysis. Part 2. Clinical topics].

  2007cites this paper
• Intravenous N-Acetylcysteine during Haemodialysis Reduces the Plasma Concentration of Homocysteine in Patients with End-Stage Renal Disease

  2006cites this paper
• Association of aminothiols with the clinical outcome in hemodialysis patients: comparison of chromatography and immunoassay for homocysteine determination

  2006cites this paper
• Correlations between concentrations of plasma homocysteine and phospholipid fatty acids in healthy male Australian

  2006cites this paper
• A significant inverse relationship between concentrations of plasma homocysteine and phospholipid docosahexaenoic acid in healthy male subjects

  2006cites this paper
• Reviews: Altered Laboratory Findings Associated with End‐Stage Renal Disease

  2006cites this paper
• Spinal cord stimulation in hemodialysis patients with critical lower-limb ischemia.

  2006cites this paper
• Altered laboratory findings associated with end-stage renal disease.

  2006cites this paper
• Influence of Homocysteine on the Function of Native Arteriovenous Fistula in Hemodialysis Patients

  2006cites this paper
• Hyperhomocysteinemia, malnutrition, and inflammation in ESRD patients.

  2006cites this paper
• pidemiology of Dialysis atients and Heart Failure Patients

  2006cites this paper
• Impact of malnutrition-inflammation on the association between homocysteine and mortality.

  2006cites this paper
• Epidemiology of dialysis patients and heart failure patients.

  2006cites this paper
• The phenomenon of altered risk factor patterns or reverse epidemiology in persons with advanced chronic kidney failure.

  2005cites this paper
• K/DOQI clinical practice guidelines for cardiovascular disease in dialysis patients.

  2005cites this paper
• [Efficacy and safety of two vitamin supplement regimens on homocysteine levels in hemodialysis patients. Prospective, randomized clinical trial].

  2005cites this paper
• Cellular Uptake of Vitamin B12 in Patients with Chronic Renal Failure

  2005cites this paper
• Correlation between dietary polyunsaturated fatty acids and plasma homocysteine concentration in vitamin B6-deficient rats.

  2005cites this paper
• Hyperhomocysteinemia in patients with mild chronic renal failure.

  2005cites this paper
• Relationship between hyperhomocysteinemia and atherosclerosis in chronic hemodialysis patients.

  2005cites this paper
• Elevated homocysteine levels in patients with end-stage renal disease.

  2005cites this paper
• PREVALENCE AND CLINICAL CORRELATES OF PERIPHERAL ARTERIAL DISEASE IN HEMODIALYSIS PATIENTS

  2005cites this paper
• Homocysteine in uraemia--a puzzling and conflicting story.

  2005cites this paper
• 57 A LOW, RATHER THAN A HIGH, TOTAL PLASMA HOMOCYSTEINE IS AN INDICATOR OF POOR OUTCOME IN HEMODIALYSIS PATIENTS.

  2004cites this paper
• Lipids and atherosclerosis

  2004cites this paper
• Serum Homocysteine , Lipoprotein ( a ) , Tumor Necrosis Factor-Alpha , Total Cholesterol and Triglyceride Levels in Hemodialysis Patients

  2004cites this paper
• Acetylcysteine Reduces Plasma Homocysteine Concentration and Improves Pulse Pressure and Endothelial Function in Patients With End-Stage Renal Failure

  2004cites this paper
• Homocysteine and atherosclerosis in dialysis patients

  2004cites this paper
• End‐stage renal failure and cardiac mortality after heart transplantation

  2004cites this paper
• Effective Homocysteine-Lowering Vitamin B Treatment in Peritoneal Dialysis Patients

  2004cites this paper
• Homocysteine-lowering therapy in renal disease.

  2003cites this paper
• The association between end-stage diabetic nephropathy and methylenetetrahydrofolate reductase genotype with macroangiopathy in type 2 diabetes mellitus.

  2003cites this paper
• The methylentetrahydrofolate reductase C677T point mutation is a risk factor for vascular access thrombosis in hemodialysis patients.

  2003cites this paper
• Reverse epidemiology of cardiovascular risk factors in maintenance dialysis patients.

  2003cites this paper
• Neither folic nor folinic acid normalize homocysteine levels in hemodialysis patients.

  2003cites this paper
• Homocysteine and cardiovascular disease in renal disease

  2003influential citation
• Homocysteine. Related Vitamins and Neuropsychiatric Disorders

  2003cites this paper
• Hyperhomocystinemia and the Prevalence of Symptomatic Atherosclerotic Vascular Disease in Taiwanese Chronic Hemodialysis Patients: A Retrospective Study

  2003cites this paper
• Homocysteine

  2003cites this paper
• Hyperhomocysteinemia and its relationship to cardiovascular disease in ESRD: influence of hypoalbuminemia, malnutrition, inflammation, and diabetes mellitus.

  2003cites this paper
• Controlled trials of very high dose folic acid, vitamins B12 and B6, intravenous folinic acid and serine for treatment of hyperhomocysteinemia in ESRD.

  2003cites this paper
• The effect of calcineurin inhibitors on endothelial function in renal transplant recipients

  2003cites this paper
• Automated Fluorescence Polarization Immunoassay for Measurement of Increased Total Homocysteine Plasma Concentrations in Hemodialysis Patients

  2003cites this paper
• Does Amino Acid–Based Peritoneal Dialysate Change Homocysteine Metabolism in Continuous Ambulatory Peritoneal Dialysis Patients?

  2003cites this paper
• Impairment of Vascular Responses to Reactive Hyperemia and Nitric Oxide in Chronic Renal Failure

  2002cites this paper
• Homocysteine, cysteine, and B vitamins as predictors of kidney disease progression.

  2002cites this paper
• Why are homocysteine levels increased in kidney failure? A metabolic approach.

  2002cites this paper
• Methylenetetrahydrofolate reductase genotype, vitamin B12, and folate influence plasma homocysteine in hemodialysis patients.

  2002cites this paper
• Serum homocysteine concentration is related to diabetes mellitus, but not to coronary heart disease, in Saudi Arabians

  2002cites this paper
• Section VII. Vascular disease and risk factors.

  2002cites this paper
• Relationship of renal function to homocysteine and lipoprotein(a) levels: the frequency of the combination of both risk factors in chronic renal impairment.

  2002cites this paper
• Hyperhomocysteinemia predicts cardiovascular outcomes in hemodialysis patients.

  2002cites this paper
• Focus on Homocysteine and the Vitamins

  2002cites this paper
• The effect of long-term intravenous high dose B-complex vitamins with or without folic acid on serum homocysteine in hemodialysis patients.

  2002cites this paper
• Mean Platelet Volume and Coronary Heart Disease in Hemodialysis Patients

  2002cites this paper
• Association of hyperhomocysteinemia with plasma sulfate and urine sulfate excretion in patients with progressive renal disease.

  2002cites this paper
• High performance liquid chromatography with fluorimetric detection for the determination of total homocysteine in human plasma: Method and clinical applications

  2001cites this paper
• Total Plasma Homocysteine and Related Amino Acids in End-Stage Renal Disease (ESRD) Patients Measured by Gas Chromatography-Mass Spectrometry – Comparison with the Abbott IMx Homocysteine Assay and the HPLC Method

  2001cites this paper
• [Cardiovascular disease in kidney transplantation].

  2001cites this paper
• Hyperhomocysteinemia in Chronic Renal Failure Patients: Relation to Nutritional Status and Cardiovascular Disease

  2001cites this paper
• Poor long-term survival after coronary angiography in patients with renal insufficiency.

  2001cites this paper
• Homocysteine and cardiovascular disease in diabetes mellitus.

  2001cites this paper
• An MTHFR variant, homocysteine, and cardiovascular comorbidity in renal disease.

  2001cites this paper
• Methylenetetrahydrofolate Reductase Gene Polymorphism, Hyperhomocysteinemia, and Cardiovascular Diseases in Chronic Hemodialysis Patients

  2001cites this paper
• The relationship between hyperhomocysteinemia and folic acid in hemodialysis patients

  2001cites this paper
• Do Different Dialytic Techniques Have Different Atherosclerotic and Antioxidant Activities?

  2001cites this paper
• Homocyst(e)in, endotheliale Dysfunktion und kardiovaskuläres Risiko

  2001cites this paper
• [Homocysteine, endothelial dysfunction and cardiovascular risk: pathomechanisms and therapeutic options].

  2001cites this paper
• [Effect of folic acid supplementation on total homocysteine levels in hemodialysis patients].

  2001cites this paper
• Cystatin C is an independent predictor of fasting and post-methionine load total homocysteine concentrations among stable renal transplant recipients.

  2001cites this paper
• Homocyst(e)ine metabolism in hemodialysis patients treated with vitamins B6, B12 and folate.

  2001cites this paper