The chromaffin cell: paradigm in cell, developmental and growth factor biology.

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Journal of Anatomy

• Publication date

  1993-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 8300412PMCID PMC1259903
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Immunocytochemical mapping of basic fibroblast growth factor in the developing and adult rat adrenal gland

  2006cited by this paper
• Fluorescence histochemical evidence for axonal growth and secretion from transplanted adrenal medullary tissue

  2004cited by this paper
• Long-term effects of dexamethasone and nerve growth factor on adrenal medullary cells cultured from young adult rats

  2004cited by this paper
• Neuronal properties of monkey adrenal medulla in vitro

  2004cited by this paper
• Rodent and primate adrenal medullary cells in vitro: phenotypic plasticity in response to coculture with C6 glioma cells or NGF

  2004cited by this paper
• FGF‐2‐mediated protection of cultured mesencephalic dopaminergic neurons against MPTP and MPP+: Specificity and impact of culture conditions, non‐dopaminergic neurons, and astroglial cells

  1993cited by this paper
• FGF‐2 Modulates Dopamine and Dopamine‐related Striatal Transmitter Systems in the Intact and MPTP‐lesioned Mouse

  1993cited by this paper
• Cytokines in neural regeneration.

  1992cited by this paper
• Interleukin-1 alpha expression is inducible by cholinergic stimulation in the rat adrenal gland.

  1992cited by this paper
• Secretogranin I/Chromogranin B Is a Heparin‐Binding Adhesive Protein

  1992cited by this paper
• Screening of adrenal medullary neuropeptides for putative neurotrophic effects

  1992cited by this paper
• Exo1 and Exo2 proteins stimulate calcium-dependent exocytosis in permeabilized adrenal chromaffin cells.

  1992cited by this paper
• Molecular control of neural plasticity by the multifunctional growth factor families of the FGFs and TGF-beta s.

  1992cited by this paper
• Changes in competence determine the timing of two sequential glucocorticoid effects on sympathoadrenal progenitors.

  1992cited by this paper
• A common silencer element in the SCG10 and type II Na+ channel genes binds a factor present in nonneuronal cells but not in neuronal cells.

  1992cited by this paper
• Basic fibroblast growth factor promotes transmitter storage and synthesis in cultured chromaffin cells.

  1992cited by this paper
• The chromogranins A and B: The first 25 years and future perspectives

  1992cited by this paper
• In situ histochemical localization of type I interleukin-1 receptor messenger RNA in the central nervous system, pituitary, and adrenal gland of the mouse

  1992cited by this paper
• Organization of cortical cytoskeleton of cultured chromaffin cells and involvement in secretion as revealed by quick-freeze, deep-etching, and double-label immunoelectron microscopy

  1992cited by this paper
• Cooperative regulation of nerve growth factor synthesis and secretion in fibroblasts and astrocytes by fibroblast growth factor and other cytokines.

  1992cited by this paper
• Basic fibroblast growth factor regulates the ability of astrocytes to support hypothalamic neuronal survival in vitro.

  1991cited by this paper
• Domain structure of synaptotagmin (p65)

  1991cited by this paper
• Beta-nerve growth factor (beta-NGF) mRNA expression in the parkinsonian adrenal gland.

  1991cited by this paper
• Stimulation of rat adrenal medulla can induce differential changes in the peptide and mRNA levels of chromogranins, neuropeptides and other constituents of chromaffin granules.

  1991cited by this paper
• Isolation of the progenitor cells of the sympathoadrenal lineage from embryonic sympathetic ganglia with the SA monoclonal antibodies

  1991cited by this paper
• The generation of monoclonal antibodies that bind preferentially to adrenal chromaffin cells and the cells of embryonic sympathetic ganglia

  1991cited by this paper
• Immunoreactive Basic Fibroblast Growth Factor‐Like Proteins in Chromaffin Granules

  1991cited by this paper
• Antibody markers identify a common progenitor to sympathetic neurons and chromaffin cells in vivo and reveal the timing of commitment to neuronal differentiation in the sympathoadrenal lineage

  1991cited by this paper
• Localization and actions of transforming growth factor-beta s in the embryonic nervous system.

  1991cited by this paper
• The neurotrophic effects of fibroblast growth factors on dopaminergic neurons in vitro are mediated by mesencephalic glia [published erratum appears in J Neurosci 1992 Mar;12(3):685]

  1991cited by this paper
• Intracerebral grafting: a tool for the neurobiologist.

  1991cited by this paper
• Mechanism of nerve growth factor mRNA regulation by interleukin-1 and basic fibroblast growth factor in primary cultures of rat astrocytes.

  1991cited by this paper
• Control of exocytosis in adrenal chromaffin cells.

  1991cited by this paper
• Insulin‐Like Growth Factor‐I Enhances Tyrosine Hydroxylase Activation in Bovine Chromaffin Cells

  1991cited by this paper
• The receptor for ciliary neurotrophic factor.

  1991cited by this paper
• Techniques and concepts in exocytosis: focus on mast cells.

  1991cited by this paper
• Generation of neuronal diversity: analogies and homologies with hematopoiesis.

  1990cited by this paper
• Basic FGF reverses chemical and morphological deficits in the nigrostriatal system of MPTP-treated mice

  1990cited by this paper
• Molecules Involved in Trophic Neuron-Neuron Interaction

  1990cited by this paper
• Analysis of SCG10 gene expression in transgenic mice reveals that neural specificity is achieved through selective derepression.

  1990cited by this paper
• Basic fibroblast growth factor (bFGF), a multifunctional growth factor for neuroectodermal cells

  1990cited by this paper
• Characterization of trophic factors stored and secreted by neurons.

  1990cited by this paper
• Basic Fibroblast Growth Factor (bFGF) Immunoreactivity Is Present in Chromaffin Granules

  1990cited by this paper
• Adrenal chromaffin cells as multipotential neurons for autografts.

  1990cited by this paper
• Conformational change and localization of calpactin I complex involved in exocytosis as revealed by quick-freeze, deep-etch electron microscopy and immunocytochemistry

  1990cited by this paper
• A v-myc-immortalized sympathoadrenal progenitor cell line in which neuronal differentiation is initiated by FGF but not NGF.

  1990cited by this paper
• Intracerebral adrenal medulla grafts: a review.

  1990cited by this paper
• Control of cell fate in a vertebrate neurogenic lineage.

  1990cited by this paper
• Activation of protein kinase C is not required for exocytosis from bovine adrenal chromaffin cells. The effects of protein kinase C(19-31), Ca/CaM kinase II(291-317), and staurosporine.

  1990cited by this paper
• Maintenance of Intermediolateral Spinal Cord Neurons by Fibroblast Growth Factor Administered to the Medullectomized Rat Adrenal Gland: Dependence on Intact Adrenal Innervation and Cellular Organization of Implants

  1990cited by this paper
• Autoradiographic Localization of Insulin‐Like Growth Factor I Binding Sites in the Bovine Adrenal Gland and on Cultured Bovine Adrenal Chromaffin Cells

  1990cited by this paper
• Chromaffin grafts: survival and nerve fiber formation as a function of donor age, nerve growth factor and host sympathetic denervation.

  1990cited by this paper
• Substrate dependency of neurite outgrowth from adult human chromaffin cells. Inhibitory effects of human brain tissue.

  1990cited by this paper
• The determination of the adrenal medullary cell fate during embryogenesis.

  1989cited by this paper
• Multicenter study of autologous adrenal medullary transplantation to the corpus striatum in patients with advanced Parkinson's disease.

  1989cited by this paper
• Distribution of two distinct Ca2+ -ATPase-like proteins and their relationships to the agonist-sensitive calcium store in adrenal chromaff in cells

  1989cited by this paper
• Inhibition of exocytosis by intracellularly applied antibodies against a chromaffin granule-binding protein

  1989cited by this paper
• A role for calpactin in calcium-dependent exocytosis in adrenal chromaffin cells

  1989cited by this paper
• Inhibition of exocytosis by intracellularly applied antibodies against a chromaffin granule-binding protein

  1989cited by this paper
• Immunocytochemical localization of basic fibroblast growth factor in bovine adrenal gland, ovary, and pituitary.

  1989cited by this paper
• The tetanus toxin light chain inhibits exocytosis

  1989cited by this paper
• Simultaneous measurements of cytosolic calcium and secretion in single bovine adrenal chromaffin cells by fluorescent imaging of fura-2 in cocultured cells

  1989cited by this paper
• Basic Fibroblast Growth Factor in the Adrenal Gland

  1989cited by this paper
• Survival and neuritic growth of sympathoadrenal (chromaffin) precursor cells in vitro

  1989cited by this paper
• Separate Binding and Functional Sites for ω co‐Conotoxin and Nitrendipine Suggest Two Types of Calcium Channels in Bovine Chromaffin Cells

  1989cited by this paper
• Interleukin-1 in adrenal chromaffin cells.

  1989cited by this paper
• Transplantation into the human brain: present status and future possibilities.

  1989cited by this paper
• Hormonal regulation of insulin-like growth factor I secretion by bovine adrenal cells.

  1989cited by this paper
• The neuro‐endocrine ambiguity of sympathoadrenal cells

  1989cited by this paper
• The neural crest cell lineage problem: neuropoiesis?

  1989cited by this paper
• Development and Plasticity of a Neural Crest-Derived Neuroendocrine Sublineage

  1989cited by this paper
• Occurrence and Mechanism of Exocytosis in Adrenal Medulla and Sympathetic Nerve

  1988cited by this paper
• Insulin-like growth factors are mitogens for rat pheochromocytoma PC 12 cells.

  1988cited by this paper
• Cell Fate and Gene Expression in the Developing Neural Crest

  1988cited by this paper
• A Two‐Dimensional Electrophoresis Study of Phosphorylation and Dephosphorylation of Chromaffin Cell Proteins in Response to a Secretory Stimulus

  1988cited by this paper
• Characterization of specific insulin binding sites on chromaffin cells from bovine adrenal medulla.

  1988cited by this paper
• Basic FGF induces neuronal differentiation, cell division, and NGF dependence in chromaffin cells: a sequence of events in sympathetic development.

  1988cited by this paper
• The fine structure of chromaffin cell implants in the pain modulatory regions of the rat periaqueductal gray and spinal cord.

  1988cited by this paper
• Calpactin in exocytosis?

  1988cited by this paper
• Bovine Chromaffin Cells Have Insulin‐Like Growth Factor‐I (IGF‐I) Receptors: IGF‐I Enhances Catecholamine Secretion

  1988cited by this paper
• Neuroectodermal Cells: Storage and Release of Growth Factors

  1988cited by this paper
• Aggregation of chromaffin granules by calpactin at micromolar levels of calcium

  1988cited by this paper
• Non-chromaffin tissue plus nerve growth factor reduces experimental parkinsonism in aged rats.

  1988cited by this paper
• Acidic fibroblast growth factor stimulates adrenal chromaffin cells to proliferate and to extend neurites, but is not a long-term survival factor.

  1988cited by this paper
• Glucocorticoid- and nerve growth factor-induced changes in chromogranin A expression define two different neuronal phenotypes in PC12 cells.

  1988cited by this paper
• Insulin growth factors regulate the mitotic cycle in cultured rat sympathetic neuroblasts.

  1988cited by this paper
• A GTP-binding protein required for secretion rapidly associates with secretory vesicles and the plasma membrane in yeast.

  1988cited by this paper
• Chromaffin Cells: Modified Neurons that are Both Targets and Storage Sites of Neuronotrophic and Neurite Promoting Factors

  1987cited by this paper
• Role of fodrin in secretion

  1987cited by this paper
• Insulin-like growth factor II in human adrenal pheochromocytomas and Wilms tumors: expression at the mRNA and protein level.

  1987cited by this paper
• Cytoskeleton: role of fodrin in secretion.

  1987cited by this paper
• Morphological and Functional Correlates of Chromaffin Cell Transplants in CNS Pain Modulatory Regions a

  1987cited by this paper
• Cellular localization of somatomedin (insulin-like growth factor) messenger RNA in the human fetus.

  1987cited by this paper
• The Molecular Basis of Phenotypic Choices in the Sympathoadrenal Lineage

  1987cited by this paper
• Relationship between differentiation and terminal mitosis: chick sensory and ciliary neurons differentiate after terminal mitosis of precursor cells, whereas sympathetic neurons continue to divide after differentiation

  1987cited by this paper
• Anti-alpha-fodrin inhibits secretion from permeabilized chromaffin cells.

  1987cited by this paper
• Survival, morphology, and catecholamine storage of chromaffin cells in serum-free culture: Evidence for a survival and differentiation promoting activity in medium conditioned by purified chromaffin cells

  1987cited by this paper
• A bipotential neuroendocrine precursor whose choice of cell fate is determined by NGF and glucocorticoids.

  1986cited by this paper
• Exocytotic exposure and recycling of membrane antigens of chromaffin granules: ultrastructural evaluation after immunolabeling

  1986cited by this paper
• Glucocorticoid inhibition of transcription from episomal proopiomelanocortin gene promoter.

  1986cited by this paper

• New Concepts of Regeneration and Renewal of Adrenal Chromaffin Cells

  2025cites this paper
• GLE1 dysfunction compromises cellular homeostasis, spatial organization, and peripheral axon branching

  2024cites this paper
• Stem cells, evolutionary aspects and pathology of the adrenal medulla: A new developmental paradigm.

  2020cites this paper
• Pheochromocytomas and Paragangliomas as Causes of Endocrine Hypertension

  2019cites this paper
• The Origin of a New Progenitor Stem Cell Group in Human Development

  2018cites this paper
• The Inside Story of Adenosine

  2018cites this paper
• Evolving Clinical Presentation and Assessment of Pheochromocytoma: A Review

  2017cites this paper
• The Endocrine System

  2016cites this paper
• Neuroblastoma and Its Zebrafish Model.

  2016cites this paper
• Phox2B correlates with MYCN and is a prognostic marker for neuroblastoma development.

  2015cites this paper
• NFAT1 and NFAT3 Cooperate with HDAC4 during Regulation of Alternative Splicing of PMCA Isoforms in PC12 Cells

  2014cites this paper
• Quantitative analysis of the effect of leflunomide on neural crest cell gene regulation during early embryonic development

  2014cites this paper
• Nicotinic Receptor Alpha7 Expression during Mouse Adrenal Gland Development

  2014cites this paper
• Resolved and open issues in chromaffin cell development.

  2013cites this paper
• miR-124-regulated RhoG

  2013cites this paper
• Sympathetic neurons and chromaffin cells share a common progenitor in the neural crest in vivo

  2013cites this paper
• miR‐124‐regulated RhoG reduces neuronal process complexity via ELMO/Dock180/Rac1 and Cdc42 signalling

  2012cites this paper
• Review of the History and Current Status of Cell-Transplant Approaches for the Management of Neuropathic Pain

  2012cites this paper
• Establishment and characterization of a noradrenergic adrenal chromaffin cell line, tsAM5NE, immortalized with the temperature‐sensitive SV40 T‐antigen

  2011cites this paper
• Advances in Anatomy Embryology and Cell Biology

  2011cites this paper
• OPTIMIZATION AND VALIDATION OF A SPECIES- SPECIFIC IN VIVO APPROACH FOR STUDIES ON GROWTH AND PROGRESSION OF NEURAL CREST DERIVED TUMOURS

  2010cites this paper
• The development of the chromaffin cell lineage from the neural crest.

  2009cites this paper
• Review: The Role of Neural Crest Cells in the Endocrine System

  2009cites this paper
• Conditional inactivation of glucocorticoid receptor gene in dopamine-beta-hydroxylase cells impairs chromaffin cell survival.

  2009cites this paper
• Cell-Based Replacement Therapies for Parkinson’s Disease

  2009cites this paper
• Dehydroepiandrosterone induces a neuroendocrine phenotype in nerve growth factor-stimulated chromaffin pheochromocytoma PC12 cells.

  2008cites this paper
• Persistent expression of BMP-4 in embryonic chick adrenal cortical cells and its role in chromaffin cell development

  2008cites this paper
• Maternal perinatal undernutrition impairs chromaffin cells proliferation in the postnatal rat.

  2008cites this paper
• Neuronal differentiation elicited by glial cell line‐derived neurotrophic factor and ciliary neurotrophic factor in adrenal chromaffin cell line tsAM5D immortalized with temperature‐sensitive SV40 T‐antigen

  2008cites this paper
• The role of RAB3A in the secretory vesicle cycle

  2008cites this paper
• Maternal Perinatal Undernutrition Impairs Chromaffin Cells Proliferation in the Postnatal Rat

  2008cites this paper
• Age-dependent regulation of chromaffin cell proliferation by growth factors, dehydroepiandrosterone (DHEA), and DHEA sulfate

  2007cites this paper
• Chemical and Biological Sensing with Carbon Nanotubes in Solution

  2007cites this paper
• Activity-dependent release of transforming growth factor-beta in a neuronal network in vitro.

  2007cites this paper
• Human fetal chromaffin cells: a potential tool for cell pain therapy.

  2007cites this paper
• Development of adrenal chromaffin cells in Sf1 heterozygous mice

  2006cites this paper
• Cell therapy of pain: Characterization of human fetal chromaffin cells at early adrenal medulla development.

  2006cites this paper
• Role of DHEA and Growth Factors in Chromaffin Cell Proliferation

  2006cites this paper
• Genetically Engineered Human Mesenchymal Stem Cells Produce Met-Enkephalin at Augmented Higher Levels in Vitro

  2006cites this paper
• Gata3 participates in a complex transcriptional feedback network to regulate sympathoadrenal differentiation

  2006cites this paper
• Cell Therapy for Models of Pain and Traumatic Brain Injury

  2006cites this paper
• Maternal perinatal undernutrition alters neuronal and neuroendocrine differentiation in the rat adrenal medulla at weaning.

  2006cites this paper
• The role of Phox2B in chromaffin cell development.

  2005cites this paper
• General Discussion

  2005cites this paper
• Immunocytochemical developmental patterns of the thoracolumbar sympathetic chain in the chick and a comparison with its adrenal counterpart.

  2005cites this paper
• Lack of an adrenal cortex in Sf1 mutant mice is compatible with the generation and differentiation of chromaffin cells

  2005cites this paper
• Cells of the sympathoadrenal lineage: biological properties as donor tissue for cell-replacement therapies for Parkinson's disease.

  2005cites this paper
• Cholinoceptor-mediated control of catecholamine release from chromaffin cells in the American eel, Anguilla rostrata

  2004cites this paper
• Cell therapy for neuropathic pain in spinal cord injuries

  2004cites this paper
• Useful cell lines derived from the adrenal medulla.

  2004cites this paper
• Isoform‐specific role of transforming growth factor‐β2 in the regulation of proliferation and differentiation of murine adrenal chromaffin cells in vivo

  2004cites this paper
• TGF-ßS and Their Roles in the Regulation of Neuron Survival

  2003cites this paper
• Development of adrenal chromaffin cells is largely normal in mice lacking the receptor tyrosine kinase c-Ret.

  2003cites this paper
• Adrenal Cortex Role in Medullary Synthesis of PNMT

  2003cites this paper
• Temperature‐dependent, neurotrophic factor‐elicited, neuronal differentiation in adrenal chromaffin cell line immortalized with temperature‐sensitive SV40 T‐antigen

  2003cites this paper
• Generation of Neuroendocrine Chromaffin Cells from Sympathoadrenal Progenitors

  2002cites this paper
• TGF-betas and their roles in the regulation of neuron survival.

  2002cites this paper
• Development of chromaffin cells depends on MASH1 function.

  2002cites this paper
• TGF-beta and the regulation of neuron survival and death.

  2002cites this paper
• TGF-β and the regulation of neuron survival and death

  2002cites this paper
• Reduction of endogenous TGF-β does not affect phenotypic development of sympathoadrenal progenitors into adrenal chromaffin cells

  2001cites this paper
• Growth and neurotrophic factors regulating development and maintenance of sympathetic preganglionic neurons.

  2001cites this paper
• Immunocytochemical, Ultrastructural and Neurochemical Evidences on Synaptogenesis and Dopamine Release of Rat Chromaffin Cells Co‐Cultured with Striatal Neurons

  2000cites this paper
• The Transforming Growth Factor‐βs

  2000cites this paper
• Generation and initial characterization of conditionally immortalized chromaffin cells

  2000cites this paper
• Reduction of endogenous TGF‐β increases proliferation of developing adrenal chromaffin cells in vivo

  2000cites this paper
• Molecular cues for the development of adrenal chromaffin cells and their preganglionic innervation

  2000cites this paper
• Vimentin in Cultured Chromaffin Cells: An Immunofluorescent, Biochemical and Functional Study

  2000cites this paper
• Current topics in pheochromocytoma.

  2000cites this paper
• Co-activation of TGF-ss and cytokine signaling pathways are required for neurotrophic functions.

  2000cites this paper
• The transforming growth factor-betas: structure, signaling, and roles in nervous system development and functions.

  2000cites this paper
• Transforming growth factor-beta, but not ciliary neurotrophic factor, inhibits DNA synthesis of adrenal medullary cells in vitro.

  1999cites this paper
• Analysis of mice carrying targeted mutations of the glucocorticoid receptor gene argues against an essential role of glucocorticoid signalling for generating adrenal chromaffin cells.

  1999cites this paper
• Characterization of adrenal medullary chromaffin cells by flow cytometry.

  1999cites this paper
• Expression of neurotrophin receptors trkB and trkC and their ligands in rat adrenal gland and the intermediolateral column of the spinal cord

  1999cites this paper
• Distinct populations of macrophages in the adult rat adrenal gland: a subpopulation with neurotrophin-4-like immunoreactivity

  1998cites this paper
• The adrenergic stress response in fish: control of catecholamine storage and release.

  1998cites this paper
• Amyloid β peptide is not a candidate for the neurotrophic activities released from chromaffin cells

  1998cites this paper
• Activation of Ca2+-dependent K+ channels by cyanide in guinea pig adrenal chromaffin cells.

  1998cites this paper
• Glial Cell Line-Derived Neurotrophic Factor Requires Transforming Growth Factor-β for Exerting Its Full Neurotrophic Potential on Peripheral and CNS Neurons

  1998cites this paper
• TrkB and Neurotrophin-4 Are Important for Development and Maintenance of Sympathetic Preganglionic Neurons Innervating the Adrenal Medulla

  1998cites this paper
• Extremely low frequency magnetic fields promote neurite varicosity formation and cell excitability in cultured rat chromaffin cells.

  1997cites this paper
• Generation of cell diversity in the peripheral autonomic nervous system: the sympathoadrenal cell lineage revisited.

  1997cites this paper
• The multifunctionality of FGF-2 in the adrenal medulla

  1997cites this paper
• Neuronal Nicotinic Acetylcholine Receptors on Bovine Chromaffin Cells: Cloning, Expression, and Genomic Organization of Receptor Subunits

  1997cites this paper
• Reduced Acetylcholinesterase (AChE) Activity in Adrenal Medulla and Loss of Sympathetic Preganglionic Neurons in TrkA-Deficient, But Not TrkB-Deficient, Mice

  1997cites this paper
• Growth factors in chromaffin cells.

  1996cites this paper
• 2′‐Deoxyadenosine Induces Apoptosis in Rat Chromaffin Cells

  1996cites this paper
• Inward currents underlying action potentials in rat adrenal chromaffin cells.

  1996cites this paper
• Immunohistochemical and ultrastructural evidence of adrenal chromaffin cell subtypes in sea bass Dicentrarchus labrax (L.).

  1996cites this paper
• Expression of neurotrophins and their receptors in the developing and adult rat adrenal gland.

  1996cites this paper
• Morphochemical investigations on postnatal development of the adrenal medulla in guinea pigs.

  1996cites this paper
• Proteins from chromaffin granules promote survival of dorsal root ganglionic neurons: comparison with neurotrophins.

  1996cites this paper
• Trophic factors made by adrenal chromaffin cells and their putative clinical implications

  1995cites this paper
• Phenotypic development of neonatal rat chromaffin cells in response to adrenal growth factors and glucocorticoids: focus on pituitary adenylate cyclase activating polypeptide.

  1995cites this paper
• Molecular cloning and functional expression of potassium channels from the adrenal medulla.

  1994cites this paper
• Effects of ACTH and aminoglutethimide on the catecholamine content and chromaffin cell morphology of the adrenal medulla of the neonatal rat.

  1993cites this paper