Reproducibility and variability of quantitative magnetic resonance imaging markers in cerebral small vessel disease

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of Cerebral Blood Flow and Metabolism

• Publication date

  2016-05-11

• Fields of study

  Medicine

• Identifiers
  DOI 10.1177/0271678X16647396PMID 27170700PMCID PMC4976752
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Vascular cognitive impairment

  2018cited by this paper
• Development and initial evaluation of a semi-automatic approach to assess perivascular spaces on conventional magnetic resonance images

  2016cited by this paper
• Pooling Morphometric Estimates: A Statistical Equivalence Approach

  2016cited by this paper
• Blood pressure and sodium: Association with MRI markers in cerebral small vessel disease

  2016cited by this paper
• On the computational assessment of white matter hyperintensity progression: difficulties in method selection and bias field correction performance on images with significant white matter pathology

  2016cited by this paper
• Visualization of perivascular spaces in the human brain at 7 T: sequence optimization and morphology characterization

  2016cited by this paper
• Use of Brain MRI Atlases to Determine Boundaries of Age-Related Pathology: The Importance of Statistical Method

  2015cited by this paper
• Computer-aided detection of cerebral microbleeds in susceptibility-weighted imaging

  2015cited by this paper
• Virchow-Robin Spaces: Correlations with Polysomnography-Derived Sleep Parameters.

  2015cited by this paper
• Man Versus Machine Part 2: Comparison of Radiologists' Interpretations and NeuroQuant Measures of Brain Asymmetry and Progressive Atrophy in Patients With Traumatic Brain Injury.

  2015cited by this paper
• White matter hyperintensities, cognitive impairment and dementia: an update

  2015cited by this paper
• Diurnal fluctuations in brain volume: Statistical analyses of MRI from large populations

  2015cited by this paper
• Cerebral Perivascular Spaces Visible on Magnetic Resonance Imaging: Development of a Qualitative Rating Scale and its Observer Reliability

  2015cited by this paper
• Handling changes in MRI acquisition parameters in modeling whole brain lesion volume and atrophy data in multiple sclerosis subjects: Comparison of linear mixed-effect models

  2015influential reference
• Brain volumetric changes and cognitive ageing during the eighth decade of life

  2015cited by this paper
• The emerging science of quantitative imaging biomarkers terminology and definitions for scientific studies and regulatory submissions

  2015cited by this paper
• Harmonic analysis for the characterization and correction of geometric distortion in MRI.

  2014cited by this paper
• Visible Virchow-Robin Spaces on Magnetic Resonance Imaging of Alzheimer's Disease Patients and Normal Elderly from the Sunnybrook Dementia Study

  2014cited by this paper
• Fully-automated quality assurance in multi-center studies using MRI phantom measurements.

  2014cited by this paper
• The SIENA/FSL whole brain atrophy algorithm is no more reproducible at 3T than 1.5 T for Alzheimer's disease.

  2014cited by this paper
• Semi-Automated Detection of Cerebral Microbleeds on 3.0 T MR Images

  2013cited by this paper
• Improved volumetric measurement of brain structure with a distortion correction procedure using an ADNI phantom.

  2013cited by this paper
• Rating Method for Dilated Virchow–Robin Spaces on Magnetic Resonance Imaging

  2013cited by this paper
• Cerebral microbleeds are related to subjective cognitive failures: the RUN DMC study.

  2013cited by this paper
• Comparison of ESWAN, SWI-SPGR, and 2D T2*-Weighted GRE Sequence for Depicting Cerebral Microbleeds

  2013cited by this paper
• Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration

  2013influential reference
• Towards the automatic computational assessment of enlarged perivascular spaces on brain magnetic resonance images: A systematic review

  2013cited by this paper
• Strictly Lobar Microbleeds Are Associated With Executive Impairment in Patients With Ischemic Stroke or Transient Ischemic Attack

  2013cited by this paper
• Review of automatic segmentation methods of multiple sclerosis white matter lesions on conventional magnetic resonance imaging

  2013cited by this paper
• Susceptibility-Weighted Imaging is More Reliable Than T2*-Weighted Gradient-Recalled Echo MRI for Detecting Microbleeds

  2013cited by this paper
• Mechanisms of Cognitive Impairment in Cerebral Small Vessel Disease: Multimodal MRI Results from the St George's Cognition and Neuroimaging in Stroke (SCANS) Study

  2013cited by this paper
• A systematic review of the utility of 1.5 versus 3 Tesla magnetic resonance brain imaging in clinical practice and research

  2012cited by this paper
• Efficient detection of cerebral microbleeds on 7.0 T MR images using the radial symmetry transform

  2012cited by this paper
• Combining atlas-based parcellation of regional brain data acquired across scanners at 1.5 T and 3.0 T field strengths

  2012cited by this paper
• Contrast-Based Fully Automatic Segmentation of White Matter Hyperintensities: Method and Validation

  2012cited by this paper
• Reliability of Longitudinal Brain Volume Loss Measurements between 2 Sites in Patients with Multiple Sclerosis: Comparison of 7 Quantification Techniques

  2012cited by this paper
• Reproducibility of Structural, Resting-State BOLD and DTI Data between Identical Scanners

  2012cited by this paper
• A Short-Term Scan–Rescan Reliability Test Measuring Brain Tissue and Subcortical Hyperintensity Volumetrics Obtained Using the Lesion Explorer Structural MRI Processing Pipeline

  2012cited by this paper
• Quantitative and qualitative assessment of structural magnetic resonance imaging data in a two-center study

  2012cited by this paper
• Brain atrophy accelerates cognitive decline in cerebral small vessel disease

  2012cited by this paper
• Cerebral microbleed detection and mapping: principles, methodological aspects and rationale in vascular dementia.

  2012cited by this paper
• Multi-stage segmentation of white matter hyperintensity, cortical and lacunar infarcts

  2012cited by this paper
• Effects of MRI scan acceleration on brain volume measurement consistency

  2012cited by this paper
• Cerebral microbleeds: burden assessment by using quantitative susceptibility mapping.

  2012cited by this paper
• Cerebral small-vessel disease and progression of brain atrophy

  2012cited by this paper
• 3D FLAIRED: 3D fluid attenuated inversion recovery for enhanced detection of lesions in multiple sclerosis

  2012cited by this paper
• Cerebral microbleeds a guide to detection and interpretation

  2012cited by this paper
• Cerebral microbleeds are associated with worse cognitive function

  2012cited by this paper
• 7 tesla MRI of microbleeds and white matter lesions as seen in vascular dementia

  2011cited by this paper
• Wide Variation in Definition, Detection, and Description of Lacunar Lesions on Imaging

  2011cited by this paper
• Lesion Explorer: A comprehensive segmentation and parcellation package to obtain regional volumetrics for subcortical hyperintensities and intracranial tissue

  2011cited by this paper
• Microbleed Detection Using Automated Segmentation (MIDAS): A New Method Applicable to Standard Clinical MR Images

  2011cited by this paper
• Effect of scanner in longitudinal studies of brain volume changes

  2011cited by this paper
• Microbleeds Are Independently Related to Gait Disturbances in Elderly Individuals With Cerebral Small Vessel Disease

  2011cited by this paper
• Assessment of the impact of the scanner-related factors on brain morphometry analysis with Brainvisa

  2011cited by this paper
• Multi-parametric neuroimaging reproducibility: A 3-T resource study

  2011cited by this paper
• Semiautomated detection of cerebral microbleeds in magnetic resonance images.

  2011cited by this paper
• A comparison of MR based segmentation methods for measuring brain atrophy progression

  2011cited by this paper
• O2‐04‐03: Atherosclerosis and progression of brain atrophy: The SMART‐MR study

  2011cited by this paper
• Assessing the reproducibility of the SienaX and Siena brain atrophy measures using the ADNI back-to-back MP-RAGE MRI scans.

  2011cited by this paper
• Clinical Relevance of Improved Microbleed Detection by Susceptibility-Weighted Magnetic Resonance Imaging

  2011cited by this paper
• Cerebral Microbleeds on MR Imaging: Comparison between 1.5 and 7T

  2011cited by this paper
• Impact of MRI markers in subcortical vascular dementia: a multi-modal analysis in CADASIL.

  2010cited by this paper
• Correlation of hypointensities in susceptibility-weighted images to tissue histology in dementia patients with cerebral amyloid angiopathy: a postmortem MRI study

  2010cited by this paper
• Intra- and interscanner variability of automated voxel-based volumetry based on a 3D probabilistic atlas of human cerebral structures

  2010cited by this paper
• Gradient distortions in MRI: Characterizing and correcting for their effects on SIENA-generated measures of brain volume change

  2010influential reference
• Disease modeling in multiple sclerosis: Assessment and quantification of sources of variability in brain parenchymal fraction measurements

  2010cited by this paper
• Accuracy and reproducibility study of automatic MRI brain tissue segmentation methods

  2010cited by this paper
• Impact of scanner hardware and imaging protocol on image quality and compartment volume precision in the ADNI cohort

  2010cited by this paper
• Effects of gradient non‐linearity correction and intensity non‐uniformity correction in longitudinal studies using structural image evaluation using normalization of atrophy (SIENA)

  2010cited by this paper
• Choice of echo time on GRE T2*-weighted MRI influences the classification of brain microbleeds.

  2010cited by this paper
• Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges.

  2010cited by this paper
• Assessment of the increase in variability when combining volumetric data from different scanners

  2009cited by this paper
• MRI-derived measurements of human subcortical, ventricular and intracranial brain volumes: Reliability effects of scan sessions, acquisition sequences, data analyses, scanner upgrade, scanner vendors and field strengths

  2009influential reference
• The Microbleed Anatomical Rating Scale (MARS)

  2009cited by this paper
• Three-Dimensional MRI Analysis of Individual Volume of Lacunes in CADASIL

  2009cited by this paper
• Reliability of MRI-derived cortical and subcortical morphometric measures: Effects of pulse sequence, voxel geometry, and parallel imaging

  2009cited by this paper
• Cerebral Atrophy in Cerebrovascular Disorders

  2009cited by this paper
• Automatic quality assessment in structural brain magnetic resonance imaging

  2009cited by this paper
• Cadasil.

  2009cited by this paper
• Cerebral microbleeds: a guide to detection and interpretation.

  2009cited by this paper
• Prospective multi-centre Voxel Based Morphometry study employing scanner specific segmentations: Procedure development using CaliBrain structural MRI data

  2009cited by this paper
• Improving Interrater Agreement About Brain Microbleeds: Development of the Brain Observer MicroBleed Scale (BOMBS)

  2009cited by this paper
• Segmentation of age-related white matter changes in a clinical multi-center study

  2008cited by this paper
• Microbleed topography, leukoaraiosis, and cognition in probable Alzheimer disease from the Sunnybrook dementia study.

  2008influential reference
• Automated quality control of brain MR images

  2008cited by this paper
• Cerebral microbleeds: accelerated 3D T2*-weighted GRE MR imaging versus conventional 2D T2*-weighted GRE MR imaging for detection.

  2008influential reference
• Signal decay due to susceptibility-induced intravoxel dephasing on multiple air-filled cylinders: MRI simulations and experiments

  2008cited by this paper
• MR Imaging Detection of Cerebral Microbleeds: Effect of Susceptibility-Weighted Imaging, Section Thickness, and Field Strength

  2008cited by this paper
• Measurement of brain atrophy in subcortical vascular disease: A comparison of different approaches and the impact of ischaemic lesions

  2008cited by this paper
• Detection of asymptomatic cerebral microbleeds: a comparative study at 1.5 and 3.0 T.

  2008cited by this paper
• Longitudinal and cross-sectional analysis of atrophy in Alzheimer's disease: Cross-validation of BSI, SIENA and SIENAX

  2007cited by this paper
• An automated procedure for the assessment of white matter hyperintensities by multispectral (T1, T2, PD) MRI and an evaluation of its between-centre reproducibility based on two large community databases

  2007cited by this paper
• Brain Atrophy Is Related to Lacunar Lesions and Tissue Microstructural Changes in CADASIL

  2007cited by this paper
• Reliability in multi-site structural MRI studies: Effects of gradient non-linearity correction on phantom and human data

  2006cited by this paper
• Multicenter assessment of reliability of cranial MRI.

  2006cited by this paper
• Vascular cognitive impairment

  2006cited by this paper
• Measuring longitudinal white matter changes: comparison of a visual rating scale with a volumetric measurement.

  2006cited by this paper
• Common MRI acquisition non-idealities significantly impact the output of the boundary shift integral method of measuring brain atrophy on serial MRI

  2006influential reference
• Brain volume changes in CADASIL

  2006cited by this paper

• A robust automated segmentation method for white matter hyperintensity of vascular-origin

  2025cites this paper
• Vascular Dementia: From Pathophysiology to Therapeutic Frontiers

  2025cites this paper
• HARMONISATION – A multimodal prospective study of vascular cognitive impairment in multi-ethnic Asians: Cohort profile, progress, current contributions, and future impact

  2025cites this paper
• Endothelial Dysfunction and Pre-Existing Cognitive Disorders in Stroke Patients

  2024cites this paper
• Assessment of arterial pulsatility of cerebral perforating arteries using 7T high‐resolution dual‐VENC phase‐contrast MRI

  2024cites this paper
• Cerebral microbleeds and risk of symptomatic hemorrhagic transformation following mechanical thrombectomy for large vessel ischemic stroke

  2024cites this paper
• Linking peripheral atherosclerosis to blood–brain barrier disruption: elucidating its role as a manifestation of cerebral small vessel disease in vascular cognitive impairment

  2024cites this paper
• segcsvdWMH : A Convolutional Neural Network‐Based Tool for Quantifying White Matter Hyperintensities in Heterogeneous Patient Cohorts

  2024cites this paper
• Altered brain spontaneous activity in patients with cerebral small vessel disease using the amplitude of low-frequency fluctuation of different frequency bands

  2023cites this paper
• Blood-brain barrier leakage in Alzheimer's disease: From discovery to clinical relevance.

  2022cites this paper
• Imaging Markers of Vascular Brain Health: Quantification, Clinical Implications, and Future Directions

  2022cites this paper
• Total Burden of Cerebral Small Vessel Disease on MRI May Predict Cognitive Impairment in Parkinson’s Disease

  2022cites this paper
• Validation of cross-sectional and longitudinal ComBat harmonization methods for magnetic resonance imaging data on a travelling subject cohort

  2022cites this paper
• Framework for Clinical Trials in Cerebral Small Vessel Disease (FINESSE): A Review.

  2022cites this paper
• Short-term repeatability and long-term reproducibility of quantitative MR imaging biomarkers in a single centre longitudinal study

  2022cites this paper
• The Epidermal Growth Factor Domain of the Mutation Does Not Appear to Influence Disease Progression in CADASIL When Brain Volume and Sex Are Taken into Account

  2022cites this paper
• Deep Learning in Large and Multi-Site Structural Brain MR Imaging Datasets

  2022cites this paper
• Neuropsychiatric symptoms as a sign of small vessel disease progression in cognitive impairment

  2022cites this paper
• The Contribution of Small Vessel Disease to Neurodegeneration: Focus on Alzheimer’s Disease, Parkinson’s Disease and Multiple Sclerosis

  2021influential citation
• Cerebral microbleeds: from depiction to interpretation

  2021cites this paper
• Differences in cerebral small vessel disease magnetic resonance imaging markers between lacunar stroke and non–Lobar intracerebral hemorrhage

  2021cites this paper
• Imaging neurovascular, endothelial and structural integrity in preparation to treat small vessel diseases. The INVESTIGATE-SVDs study protocol. Part of the SVDs@Target project

  2021cites this paper
• Challenges in ensuring the generalizability of image quantitation methods for MRI.

  2021cites this paper
• MixLacune: Segmentation of lacunes of presumed vascular origin

  2021cites this paper
• MixMicrobleed: Multi-stage detection and segmentation of cerebral microbleeds

  2021cites this paper
• MixMicrobleedNet: segmentation of cerebral microbleeds using nnU-Net

  2021cites this paper
• Vascular Cognitive Impairment

  2021cites this paper
• Unsupervised learning for vascular heterogeneity assessment of glioblastoma based on magnetic resonance imaging: The Hemodynamic Tissue Signature

  2020cites this paper
• Calgary Normative Study: design of a prospective longitudinal study to characterise potential quantitative MR biomarkers of neurodegeneration over the adult lifespan

  2020cites this paper
• Cornea: A Window to White Matter Changes in Stroke; Corneal Confocal Microscopy a Surrogate Marker for the Presence and Severity of White Matter Hyperintensities in Ischemic Stroke.

  2020cites this paper
• Test-retest reliability of FreeSurfer automated hippocampal subfield segmentation within and across scanners

  2020cites this paper
• Incident cerebral lacunes: A review

  2020cites this paper
• Imaging of the aging brain and development of MRI signal abnormalities.

  2020cites this paper
• Cortical superficial siderosis progression in cerebral amyloid angiopathy

  2020cites this paper
• CALGARY NORMATIVE STUDY: STUDY DESIGN OF A PROSPECTIVE LONGITUDINAL STUDY TO CHARACTERIZE POTENTIAL QUANTITATIVE MR BIOMARKERS OVER THE ADULT LIFESPAN

  2020cites this paper
• Assessment of brain volumes obtained from MP-RAGE and MP2RAGE images, quantified using different segmentation methods

  2020cites this paper
• White matter hyperintensities classified according to intensity and spatial location reveal specific associations with cognitive performance

  2020cites this paper
• White Matter Hyperintensities Quantification in Healthy Adults: A Systematic Review and Meta‐Analysis

  2020influential citation
• Impact of vascular risk factors on clinical outcome in elderly patients with depression receiving electroconvulsive therapy.

  2020cites this paper
• The glymphatic system and its role in cerebral homeostasis.

  2020cites this paper
• A Review of Translational Magnetic Resonance Imaging in Human and Rodent Experimental Models of Small Vessel Disease

  2020cites this paper
• Prospects for Diminishing the Impact of Nonamyloid Small-Vessel Diseases of the Brain.

  2020cites this paper
• Robust association between vascular habitats and patient prognosis in glioblastoma: An international multicenter study

  2020cites this paper
• Brain atrophy in cerebral small vessel diseases: Extent, consequences, technical limitations and perspectives: The HARNESS initiative

  2019cites this paper
• Clinical correlates of longitudinal MRI changes in CADASIL

  2019cites this paper
• Big Data, Artificial Intelligence, and Machine Learning in Neurotrauma

  2019cites this paper
• Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration

  2019cites this paper
• Neuroimaging of Cerebral Small Vessel Disease and Age-Related Cognitive Changes

  2019cites this paper
• Effect of cerebral small vessel disease on cognitive function and TLR4 expression in hippocampus.

  2019cites this paper
• Reproducibility of Structural and Diffusion Tensor Imaging in the TACERN Multi-Center Study

  2019cites this paper
• Post-acquisition Processing Confounds in Brain Volumetric Quantification of White Matter Hyperintensities.

  2019cites this paper
• Cerebral Small-Vessel Disease

  2019cites this paper
• Performance of five automated white matter hyperintensity segmentation methods in a multicenter dataset

  2019cites this paper
• Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy: Lessons From Neuroimaging.

  2019influential citation
• Cognitive dysfunction and brain atrophy in Susac syndrome

  2019cites this paper
• Imaging in Cerebral Small Vessel Disease

  2019cites this paper
• Multicenter Imaging Studies: Automated Approach to Evaluating Data Variability and the Role of Outliers

  2018cites this paper
• White matter hyperintensity shape and location feature analysis on brain MRI; proof of principle study in patients with diabetes

  2018cites this paper
• Quantitative and qualitative MRI evaluation of cerebral small vessel disease in an elderly population: a longitudinal study

  2018cites this paper
• Improved detection of cerebrovascular disease processes: Introduction to the Journal of Cerebral Blood Flow and Metabolism special issue on cerebrovascular disease

  2018cites this paper
• Understanding the role of the perivascular space in cerebral small vessel disease

  2018cites this paper
• Plasma A&bgr; (Amyloid-&bgr;) Levels and Severity and Progression of Small Vessel Disease

  2018cites this paper
• Edinburgh Explorer Considerations on accuracy, pattern and possible underlying factors of brain microbleeds progression on older adults with absence or mild presence of vascular pathology

  2018influential citation
• Neuroimaging in Cerebral Small Vessel Disease

  2018cites this paper
• Cerebral small vessel disease and risk of incident stroke, dementia and depression, and all-cause mortality: A systematic review and meta-analysis

  2018cites this paper
• Validation and Optimization of BIANCA for the Segmentation of Extensive White Matter Hyperintensities

  2018cites this paper
• Small Vessel Disease on Neuroimaging in a 75-Year-Old Cohort (PIVUS): Comparison With Cognitive and Executive Tests

  2018cites this paper
• The Additional Value of PET in the Assessment of Cerebral Small Vessel Disease

  2018influential citation
• Serum Neurofilament Light Chain Levels Are Related to Small Vessel Disease Burden

  2018cites this paper
• Cerebral small vessel disease: from a focal to a global perspective

  2018cites this paper
• The relationship between white matter lesion volume with vascular stiffness, mobility and cognitive performance in older adults with vascular cognitive impairment

  2018cites this paper
• Unraveling the heterogeneity of cerebral small vessel disease. From local to remote effects

  2018cites this paper
• Considerations on accuracy, pattern and possible underlying factors of brain microbleed progression in older adults with absence or mild presence of vascular pathology

  2018cites this paper
• Investigating the origin and evolution of cerebral small vessel disease: The RUN DMC – InTENse study

  2018cites this paper
• MRI for in vivo diagnosis of cerebral amyloid angiopathy: Tailoring artifacts to image hemorrhagic biomarkers.

  2017influential citation
• Disease progression and regression in sporadic small vessel disease-insights from neuroimaging.

  2017cites this paper
• Different types of white matter hyperintensities in CADASIL: Insights from 7-Tesla MRI

  2017cites this paper
• Detection and characterization of small infarcts in the caudate nucleus on 7 Tesla MRI: The SMART-MR study

  2017cites this paper
• Imaging Morphologic Substrates and Molecular Changes for Differential Diagnosis of Vascular Dementia

  2017cites this paper
• Early-onset and delayed-onset poststroke dementia — revisiting the mechanisms

  2017cites this paper
• New insights into cerebral small vessel disease and vascular cognitive impairment from MRI

  2017cites this paper
• White matter changes and gait decline in cerebral small vessel disease

  2017cites this paper
• Using DTI to assess white matter microstructure in cerebral small vessel disease (SVD) in multicentre studies

  2017cites this paper
• Advanced Neuroimaging of Cerebral Small Vessel Disease

  2017cites this paper
• Consensus statement on current and emerging methods for the diagnosis and evaluation of cerebrovascular disease

  2017cites this paper
• Maximizing the Potential of Longitudinal Cohorts for Research in Neurodegenerative Diseases: A Community Perspective

  2017cites this paper
• Worldwide collaboration in the Microbleeds International Collaborative Network.

  2016cites this paper
• Robustness of Automated Methods for Brain Volume Measurements across Different MRI Field Strengths

  2016cites this paper
• Diagnostic value of neuro-ophthalmological signs in cases of Chiari I malformation

  2016cites this paper