Medically Unexplained Physical Symptoms, Anxiety, and Depression: A Meta‐Analytic Review

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Psychosomatic Medicine

• Publication date

  2003-07-01

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1097/01.PSY.0000075977.90337.E7PMID 12883101
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• How do you feel? Interoception: the sense of the physiological condition of the body

  2002cited by this paper
• Depression in Rheumatoid Arthritis: A Systematic Review of the Literature With Meta-Analysis

  2002cited by this paper
• Medical Symptoms without Identified Pathology: Relationship to Psychiatric Disorders, Childhood and Adult Trauma, and Personality Traits

  2001cited by this paper
• Medically unexplained symptoms in frequent attenders of secondary health care: retrospective cohort study

  2001cited by this paper
• Discriminating between chronic fatigue syndrome and depression: a cognitive analysis

  2001cited by this paper
• A Review of the Evidence for Overlap among Unexplained Clinical Conditions

  2001cited by this paper
• Cerebral Activation in Patients With Irritable Bowel Syndrome and Control Subjects During Rectosigmoid Stimulation

  2001cited by this paper
• Unexplained Somatic Symptoms, Functional Syndromes, and Somatization: Do We Need a Paradigm Shift?

  2001cited by this paper
• Somatoform disorders: severe psychiatric illnesses neglected by psychiatrists

  2001cited by this paper
• Psychosocial aspects of fibromyalgia

  2001cited by this paper
• Systematic Reviews in Health Care

  2001cited by this paper
• Evaluating latent variable models of functional somatic distress in a community-based sample

  2001cited by this paper
• Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group.

  2000cited by this paper
• Mind beyond the Net: Implications of Cognitive Neuroscience for Cultural Psychiatry

  2000cited by this paper
• [Functional somatic syndromes].

  2000cited by this paper
• Symptom expression in pain-predominant functional bowel syndrome: is visceral hyperalgesia the whole truth?

  2000cited by this paper
• Psychotherapy for patients with complex disorders and chronic symptoms

  2000cited by this paper
• Cognitive-Behavioral Therapy for Somatization and Symptom Syndromes: A Critical Review of Controlled Clinical Trials

  2000cited by this paper
• Somatization in primary care: it's time for parity.

  2000cited by this paper
• What determines severity among patients with painful functional bowel disorders?

  2000cited by this paper
• Functional Somatic Syndromes

  1999cited by this paper
• Somatic distress as a distinct psychological dimension

  1999cited by this paper
• A taxonomy of medically unexplained symptoms.

  1999cited by this paper
• Functional somatic syndromes: one or many?

  1999cited by this paper
• A taxonomy of medically unexplained symptoms.

  1999cited by this paper
• Antidepressant therapy for unexplained symptoms and symptom syndromes.

  1999cited by this paper
• Somatic complaints disproportionately contribute to Beck Depression Inventory estimates of depression severity in individuals with multiple chemical sensitivity.

  1998cited by this paper
• All roads lead to depression: clinically homogeneous, etiologically heterogeneous.

  1997cited by this paper
• Recognition of common mental disorders in primary care in African countries: should "mental" be dropped?

  1996cited by this paper
• The Relationship Between Pain and Depression

  1996cited by this paper
• A Dimensional Model for Common Mental Disorders

  1996cited by this paper
• The structure of common psychiatric symptoms: how many dimensions of neurosis?

  1995cited by this paper
• Invited commentary: benefits of heterogeneity in meta-analysis of data from epidemiologic studies.

  1995cited by this paper
• Can meta-analysis be salvaged?

  1994cited by this paper
• Somatoform disorders: personality and the social matrix of somatic distress.

  1994cited by this paper
• Physical symptoms in primary care. Predictors of psychiatric disorders and functional impairment.

  1994cited by this paper
• Effects of deficient reporting on meta-analysis: a conceptual framework and reanalysis.

  1985influential reference

• Symptom expectations as a clinical target in somatic symptom disorder: Cross-sectional evidence from the SOMA.SSD study.

  2026cites this paper
• Gastroduodenal Disorders.

  2026influential citation
• Neural signatures of major depressive disorder with comorbid insomnia: Low gamma PoCG.R-INS.L connectivity as a potential biomarker.

  2026cites this paper
• Gastrointestinal motility disorders: from pathogenesis to therapeutic strategies

  2026cites this paper
• The Relationship Between Pain and Depression in Fibromyalgia: Structural Equation Modeling and Network Analysis

  2026cites this paper
• Ecological momentary assessment of physical symptoms among patients with a history of COVID-19 infection: towards understanding long covid and the role of mental health symptoms.

  2026cites this paper
• C-reactive protein is associated with pain-type somatic symptoms independent of mental health symptoms in adolescents: Evidence from the ALSPAC study

  2025cites this paper
• Psychological Processes Related to Persistent Physical Symptoms in Patients With a Suspected Rare Disease: a Cross-sectional Interview Study.

  2025cites this paper
• Prospective associations between major depressive disorder, generalized anxiety disorder, fibromyalgia, and myalgic encephalomyelitis/chronic fatigue syndrome

  2025cites this paper
• Clinical insights into the mechanisms of infectious microbes and microbiota in chronic neurologic and psychiatric diseases.

  2025cites this paper
• Insular Cortex—Biology and Its Role in Psychiatric Disorders: A Narrative Review

  2025cites this paper
• Exploring the Causes and Physical Manifestations of Glossophobia among University Students

  2025cites this paper
• The patient health questionnaire somatization-anxiety-depression scale: Validation of the PHQ-SAD in 4 clinical trials.

  2025cites this paper
• Somatic Symptoms Among University Students in Paraguay: The Role of Burnout, Stress, Insomnia, Anxiety, and Depression.

  2025cites this paper
• Depression vulnerability and gray matter integrity of interoceptive networks in remitted depressed outpatients.

  2025cites this paper
• Psychometric properties of the Arabic spence children’s anxiety scale parent in a sample of Arabic speaking adults

  2025cites this paper
• Research progress on the mechanisms of comorbidity between functional gastrointestinal disorders and mental disorders: A review

  2025cites this paper
• Core and bridge symptoms in self-perceived aging, depression, and anxiety among the elderly with multiple chronic conditions in Chinese communities: a network analysis perspective

  2025cites this paper
• A Randomized Cross-over Trial Comparing Life Stress Interview versus Basic Assessment of Psychiatric Symptoms for Patients with Persistent Physical Symptoms.

  2025cites this paper
• Genetic correlation, pleiotropic loci and shared risk genes between major depressive disorder and gastrointestinal tract disorders.

  2025cites this paper
• Chronic fatigue: psychometric properties and updated norm values of the Chalder fatigue scale in a cross-sectional sample representative of the German population

  2025cites this paper
• The Relationship Between Vocal Tract Discomfort Symptoms Reporting With Personality Traits and Psychological Distress.

  2025cites this paper
• Somatization and Body Composition: Findings from a Cross-Sectional Study on Non-Clinical Young Adults

  2025cites this paper
• Common misconceptions and controversies in the management of irritable bowel syndrome

  2025cites this paper
• The effects of weight self-stigma on psychological distress in adolescents: the chain-mediated roles of fear of negative appearance evaluation and social appearance anxiety

  2025cites this paper
• Prevalence of the anti-CASPR2 autoantibody in patients with somatic symptom disorder accompanied by medically unexplained pain

  2025cites this paper
• Can the pain field learn from the functional somatic disorder field?

  2025cites this paper
• Long-Term Outcomes After Therapeutic Induction in Patients with Functional Dyspepsia

  2025cites this paper
• The association between common mental disorders and tuberculosis, a case control study from Guinea Bissau.

  2024cites this paper
• Physical and psychological correlates of somatic symptom in patients with functional constipation: a cross-sectional study

  2024cites this paper
• Online acceptance and commitment therapy (iACT) for adults with persistent physical symptoms - 3-month follow-up study of a randomized controlled trial.

  2024cites this paper
• Psychische Gesundheit und somatische Symptombelastung von Patient*innen

  2024cites this paper
• Fibromyalgia and Sedentarism: Which Came First, the Chicken or the Egg?

  2024cites this paper
• Early detection of students’ mental health issues from a traditional daily health observation scheme in Japanese schools and its digitalization

  2024cites this paper
• Exploring the course of functional somatic symptoms (FSS) from pre- to late adolescence and associated internalizing psychopathology – an observational cohort-study

  2024cites this paper
• Exploring the Link Between Interoception and Symptom Severity in Premature Ventricular Contractions

  2024cites this paper
• Depression and the risk of fibromyalgia syndrome: a two-sample Mendelian randomization study

  2024cites this paper
• Five-factor personality traits and functional somatic disorder: A systematic review and meta-analysis.

  2024cites this paper
• Research priorities for medically not yet explained symptoms expressed by patients, carers, and healthcare professionals in the Netherlands following the James Lind Alliance priority setting partnership approach.

  2024cites this paper
• Somatic symptoms in the general population of Spain: Validation and normative data of the Patient Health Questionnaire-15 (PHQ-15).

  2024cites this paper
• Comorbidity and sex differences in functional disorders and internalizing disorders.

  2024cites this paper
• Network structure of functional somatic symptoms.

  2024cites this paper
• Rikkunshito improves anorexia through ghrelin‐ and orexin‐dependent activation of the brain hypothalamus and mesolimbic dopaminergic pathway in rats

  2024cites this paper
• How personality factors, coping with identity-stress, and parental rearing styles contribute to the expression of somatic complaints in emerging adults in seven countries

  2024cites this paper
• Association between exposure to violence, job stress and depressive symptoms among gig economy workers in Korea

  2023cites this paper
• Functional Somatic Disorders, Their Subtypes, and Their Association With Self-Rated Health in the German General Population

  2023cites this paper
• Exploring maladaptive cognitions and behaviors as perpetuating factors in patients with persistent somatic symptoms: a longitudinal study.

  2023cites this paper
• Novel Symptom Subgroups in Individuals with Irritable Bowel Syndrome Predict Disease Impact and Burden.

  2023cites this paper
• Global trends in research related to functional dyspepsia and anxiety or depression over the past two decades: a bibliometric analysis

  2023cites this paper
• Psychological flexibility and global health in young adults with and without a self-reported functional somatic syndrome: a preliminary investigation

  2023cites this paper
• Healthcare-related factors influencing symptom persistence, deterioration, or improvement in patients with persistent somatic symptoms: A scoping review of European studies.

  2023cites this paper
• Self-help interventions for persistent physical symptoms: a systematic review of behaviour change components and their potential effects

  2023cites this paper
• Psychiatric disorders comorbid with general medical illnesses and functional somatic disorders: The Lifelines cohort study

  2023cites this paper
• Investigating the shared genetic architecture of post-traumatic stress disorder and gastrointestinal tract disorders: a genome-wide cross-trait analysis

  2023cites this paper
• How are bodily states experienced, differentiated and translated into symptoms? A qualitative study

  2023cites this paper
• Psychiatric disorders and the onset of self-reported fibromyalgia and chronic fatigue syndrome: The lifelines cohort study

  2023cites this paper
• Gastrointestinal functional disorders can benefit from the use of medical devices made of substances

  2023cites this paper
• The Indirect Effects of Recalled Trauma Severity on Pain Ratings among People with Fibromyalgia: a Moderated Mediation Model

  2023cites this paper
• Effects of moderate-intensity aerobic exercise on cognitive fatigue relief: a randomised self-controlled study

  2023cites this paper
• Understanding Individual Differences in Mental Health and Video Games

  2023cites this paper
• A randomized controlled trial protocol for persistent physical symptoms associated with indoor environment or chronic fatigue: Effectiveness of video-based functional case conceptualization and web-program for improving quality of life

  2023cites this paper
• Update on Clinical Characteristics of Upper Airway Dyspnea: A Mixed Methods Study.

  2023cites this paper
• Migräne und psychosomatische Komorbiditäten

  2023cites this paper
• A scientometric analysis of the relationship between functional dyspepsia and anxiety

  2023cites this paper
• Validation of the Chinese version of the Somatic Symptom Scale-8 in patients from tertiary hospitals in China

  2022cites this paper
• Internet-based emotional awareness and expression therapy for somatic symptom disorder: A randomized controlled trial.

  2022cites this paper
• The Prevalence and Incidence of Irritable Bowel Syndrome and Inflammatory Bowel Disease in Depression and Bipolar Disorder: A Systematic Review and Meta-Analysis

  2022cites this paper
• Migraine in the context of chronic primary pain, chronic overlapping pain disorders, and functional somatic disorders: A narrative review

  2022cites this paper
• The role of mind body interventions in the treatment of irritable bowel syndrome and fibromyalgia

  2022cites this paper
• The Effect of Severe Pain on Transmyocardial Repolarization Parameters in Renal Colic Patients

  2022cites this paper
• Enhancing Mental Illness Prediction using Tree based Machine Learning Approach

  2022cites this paper
• Stability and predictors of somatic symptoms in men and women over 10 years: A real-world perspective from the prospective MONICA/KORA study.

  2022cites this paper
• Effect of treadmill walking for anxiety, depression, and social well-being in women with diabetes type 2: A randomized controlled trial

  2022cites this paper
• Sex Differences in Comorbidity Combinations in the Swedish Population

  2022cites this paper
• What the future holds: Machine learning to predict success in psychotherapy.

  2022cites this paper
• Mindfulness, psychological distress, and somatic symptoms among women engaged in sex work in China

  2022cites this paper
• Mental Health, Ill-Defined Conditions, and Healthcare Utilization Following Bereavement: A Prospective Case-Control Study.

  2022cites this paper
• [Functional cardiovascular symptoms].

  2022cites this paper
• Cardiorespiratory physiology, exertional symptoms, and psychological burden in post-COVID-19 fatigue

  2022cites this paper
• Risk factors in adolescence as predictors of trajectories of somatic symptoms over 27 years

  2022cites this paper
• The Effects of Sleep on Firefighter Occupational Performance and Health: A Systematic Review and Call for Action

  2021cites this paper
• Predictors of Response and Remission From Depression at 6-months of Treatment Within an Integrated Care Program

  2021cites this paper
• Under-recognition of medically unexplained symptom conditions among US Veterans with Gulf War Illness

  2021cites this paper
• Depressive symptoms and health-related quality of life in a heterogeneous psychiatric sample: conditional indirect effects of pain severity and interference

  2021cites this paper
• The interplay of interoceptive accuracy, facets of interoceptive sensibility, and trait anxiety: A network analysis

  2021cites this paper
• Beyond a symptom count

  2021cites this paper
• Factors associated with response and remission from depression at 6-months of treatment in a retrospective cohort treated within an integrated care program

  2021cites this paper
• Mental Health in Lifestyle Medicine: A Call to Action

  2021cites this paper
• Characterising DSCATT: A case series of Australian patients with debilitating symptom complexes attributed to ticks

  2021cites this paper
• Applications of Energy Psychology in Addressing the Psychological Roots of Illness

  2021cites this paper
• Somatic symptoms and associations with common psychological diagnoses: a retrospective cohort study from Norwegian urban general practice.

  2021cites this paper
• Validation of the Multidimensional Assessment of Interoceptive Awareness (MAIA-2) questionnaire in hospitalized patients with major depressive disorder

  2021cites this paper
• Embodied Knowledge – the Phenomenon of Subjective Health Complaints reflected upon by Norwegian Psychomotor Physiotherapy specialists

  2021cites this paper
• The BodyMind Approach® to support students in higher education: Relationships between student stress, medically unexplained physical symptoms and mental health

  2021cites this paper
• Association Between Irritable Bowel Syndrome and Risk of Parkinson's Disease: A Systematic Review and Meta-Analysis

  2021cites this paper
• The Association Between Heart Rate Variability and Quality of Life in Patients with Functional Somatic Syndrome and Healthy Controls

  2021cites this paper
• Health-Related Quality of Life, Depressive Symptoms, Anxiety, and Somatization Symptoms in Male and Female Patients with Chronic Tinnitus

  2021cites this paper
• Altered brain structural connectivity in patients with longstanding gut inflammation is correlated with psychological symptoms and disease duration

  2021cites this paper
• ICD-10-Coding of Medically Unexplained Physical Symptoms and Somatoform Disorders—A Survey With German GPs

  2021cites this paper
• Impact of Psychological Comorbidity on the Prognosis of Irritable Bowel Syndrome

  2021cites this paper