Human SRMAtlas: A Resource of Targeted Assays to Quantify the Complete Human Proteome.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Cell

• Publication date

  2016-07-28

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.cell.2016.06.041PMID 27453469PMCID PMC5245710
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• RNA Sequencing Identifies Novel Translational Biomarkers of Kidney Fibrosis.

  2016cited by this paper
• Non-invasive prognostic protein biomarker signatures associated with colorectal cancer

  2015cited by this paper
• Trans‐Proteomic Pipeline, a standardized data processing pipeline for large‐scale reproducible proteomics informatics

  2015cited by this paper
• State of the Human Proteome in 2014/2015 As Viewed through PeptideAtlas: Enhancing Accuracy and Coverage through the AtlasProphet.

  2015cited by this paper
• Applications of targeted proteomics in systems biology and translational medicine

  2015cited by this paper
• A century of cholesterol and coronaries: from plaques to genes to statins.

  2015cited by this paper
• Targeted Peptide Measurements in Biology and Medicine: Best Practices for Mass Spectrometry-based Assay Development Using a Fit-for-Purpose Approach

  2014cited by this paper
• Panorama: A Targeted Proteomics Knowledge Base

  2014cited by this paper
• CPTAC Assay Portal: a repository of targeted proteomic assays

  2014cited by this paper
• A complete mass-spectrometric map of the yeast proteome applied to quantitative trait analysis

  2013cited by this paper
• Quantitative analysis of peptides and proteins in biomedicine by targeted mass spectrometry

  2013cited by this paper
• The Mtb proteome library: a resource of assays to quantify the complete proteome of Mycobacterium tuberculosis.

  2013cited by this paper
• Demonstrating the feasibility of large-scale development of standardized assays to quantify human proteins

  2013cited by this paper
• Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding

  2013cited by this paper
• The coming age of complete, accurate, and ubiquitous proteomes.

  2013cited by this paper
• Targeted Data Extraction of the MS/MS Spectra Generated by Data-independent Acquisition: A New Concept for Consistent and Accurate Proteome Analysis*

  2012cited by this paper
• Downregulation of KIF23 suppresses glioma proliferation

  2012cited by this paper
• Proteome-wide selected reaction monitoring assays for the human pathogen Streptococcus pyogenes

  2012cited by this paper
• Reproducible Quantification of Cancer-Associated Proteins in Body Fluids Using Targeted Proteomics

  2012cited by this paper
• PASSEL: The PeptideAtlas SRMexperiment library

  2012cited by this paper
• Selected reaction monitoring–based proteomics: workflows, potential, pitfalls and future directions

  2012cited by this paper
• Evolving standards in the treatment of docetaxel-refractory castration-resistant prostate cancer

  2011cited by this paper
• Too many roads not taken

  2011cited by this paper
• Estimation of Absolute Protein Quantities of Unlabeled Samples by Selected Reaction Monitoring Mass Spectrometry

  2011cited by this paper
• The human genome and drug discovery after a decade. Roads (still) not taken

  2011cited by this paper
• Prediction of the human membrane proteome

  2010cited by this paper
• Overexpression of kinesins mediates docetaxel resistance in breast cancer cells.

  2009cited by this paper
• Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics.

  2009cited by this paper
• Multi-site assessment of the precision and reproducibility of multiple reaction monitoring–based measurements of proteins in plasma

  2009cited by this paper
• Bioinformatics construction of the human cell surfaceome

  2009cited by this paper
• Quantitative mass spectrometry in proteomics: a critical review

  2007cited by this paper
• Computational prediction of proteotypic peptides for quantitative proteomics

  2007cited by this paper
• UniProtKB/Swiss-Prot.

  2007cited by this paper
• Sterol dependent regulation of human TM7SF2 gene expression: role of the encoded 3beta-hydroxysterol Delta14-reductase in human cholesterol biosynthesis.

  2006cited by this paper
• Scoring proteomes with proteotypic peptide probes

  2005cited by this paper
• A Human Protein Atlas for Normal and Cancer Tissues Based on Antibody Proteomics*

  2005cited by this paper
• Integration with the human genome of peptide sequences obtained by high-throughput mass spectrometry

  2004cited by this paper
• Mass spectrometric quantitation of peptides and proteins using Stable Isotope Standards and Capture by Anti-Peptide Antibodies (SISCAPA).

  2004cited by this paper
• Single and multiple ion recording techniques for the analysis of diphenylhydantoin and its major metabolite in plasma.

  1977cited by this paper

• Serum protein profiles in lupus nephritis associated with initial-onset systemic lupus erythematosus: Characterization through PEA immunoassay and preliminary development of predictive model.

  2025cites this paper
• Data Independent Acquisition to Inform the Development of Targeted Proteomics Assays Using a Triple Quadrupole Mass Spectrometer.

  2025cites this paper
• Longitudinal Proteomic Changes in HCT 116 Colon Cancer Spheroids During Growth.

  2025cites this paper
• Proteomics-based multi-omics identifies the roadmap of transcription-translation-protein dynamics in planarian regeneration.

  2025cites this paper
• Current Methods in Clinical Alzheimer’s Disease Research and Diagnosis

  2025cites this paper
• Plasma proteome profiling identifies predictive signatures for preterm birth risk

  2025cites this paper
• Tear Protein Biomarkers for Ocular Mucous Membrane Pemphigoid Uncovered Using Targeted LC-MS/MS.

  2025cites this paper
• MRMAssayDB: a comprehensive integrated resource for targeted proteomics assays

  2025cites this paper
• Tear Sampling and Biomarker Discovery: A Robust Workflow for Routine Clinical Applications Using UHPLC-MS/MS and Schirmer Strips

  2025cites this paper
• Adaptive Modeling of Tandem Mass Spectrometry Data: Creation of the METLIN 960K MRM Database

  2025cites this paper
• Sterol Derivatives Specifically Increase Anti-Inflammatory Oxylipin Formation in M2-like Macrophages by LXR-Mediated Induction of 15-LOX

  2024cites this paper
• Cellular Characteristics and Protein Signatures of Human Adipose Tissues from Donors With or Without Advanced Coronary Artery Disease

  2024cites this paper
• ALK1 Signaling in Human Cardiac Progenitor Cells Promotes a Pro-angiogenic Secretome

  2024cites this paper
• Inhibition of the Alternative Complement Pathway May Cause Secretion of Factor B, Enabling an Early Detection of Pancreatic Cancer.

  2024cites this paper
• The Proteomics Standards Initiative Standardized Formats for Spectral Libraries and Fragment Ion Peak Annotations: mzSpecLib and mzPAF

  2024cites this paper
• Targeted Proteomics Reveals Quantitative Differences in Low-Abundance Glycosyltransferases of Patients with Congenital Disorders of Glycosylation

  2024cites this paper
• Comprehensive Overview of Bottom-Up Proteomics Using Mass Spectrometry

  2024cites this paper
• π-HuB: the proteomic navigator of the human body

  2024cites this paper
• Quantitative Peptidomics: General Considerations.

  2024cites this paper
• From flesh to bones: Multi‐omics approaches in forensic science

  2024cites this paper
• Proteomic Markers of Aging and Longevity: A Systematic Review

  2024cites this paper
• Identification of Mortalin as the Main Interactor of Mycalin A, a Poly-Brominated C-15 Acetogenin Sponge Metabolite, by MS-Based Proteomics

  2024cites this paper
• Data Independent Acquisition to Inform the Development of Targeted Proteomics Assays Using a Triple Quadrupole Mass Spectrometer

  2024cites this paper
• Rab3B Proteins: Cellular Functions, Regulatory Mechanisms, and Potential as a Cancer Therapy Target

  2024cites this paper
• Engineered Cas9 variants bypass Keap1-mediated degradation in human cells and enhance epigenome editing efficiency

  2024cites this paper
• Chemoproteomics Reveals USP5 (Ubiquitin Carboxyl-Terminal Hydrolase 5) as Promising Target of the Marine Polyketide Gracilioether A

  2024cites this paper
• Applicability of selected reaction monitoring for precise screening tests

  2024cites this paper
• Machine learning strategies to tackle data challenges in mass spectrometry-based proteomics

  2024cites this paper
• Discovery and Verification of Sjögren's Syndrome Protein Biomarkers in Tears by Targeted LC-MRM.

  2024cites this paper
• Serum/Plasma Proteome in Non-Malignant Liver Disease

  2024cites this paper
• Translational bioinformatics approach to combat cardiovascular disease and cancers.

  2024cites this paper
• Development of a Fit-For-Purpose Multi-Marker Panel for Early Diagnosis of Pancreatic Ductal Adenocarcinoma

  2024cites this paper
• A comprehensive spectral assay library to quantify the Halobacterium salinarum NRC-1 proteome by DIA/SWATH-MS

  2023influential citation
• Proteomic Investigation of COVID-19 Severity During the Tsunamic Second Wave in Mumbai.

  2023cites this paper
• DIGEST: An online tool for designing of multiple reaction monitoring assays

  2023influential citation
• Comprehensive Overview of Bottom-Up Proteomics using Mass Spectrometry

  2023cites this paper
• A single protein to multiple peptides: Investigation of protein-peptide correlations using targeted alpha-2-macroglobulin analysis.

  2023cites this paper
• The Breast Cancer Proteome and Precision Oncology.

  2023cites this paper
• Application of peptide barcoding to obtain high-affinity anti-PD-1 nanobodies

  2023cites this paper
• Targeted Workflow Investigating Variations in the Tear Proteome by Liquid Chromatography Tandem Mass Spectrometry

  2023cites this paper
• Bioinformatics Tools and Knowledgebases to Assist Generating Targeted Assays for Plasma Proteomics.

  2023cites this paper
• MILKSHAKE Western blot and Sundae ELISA: We all scream for better antibody validation.

  2023cites this paper
• Signature peptide selection workflow for biomarker quantification using LC-MS based targeted proteomics.

  2023cites this paper
• Docetaxel radiosensitizes castration-resistant prostate cancer by downregulating CAV-1

  2023cites this paper
• A Galaxy of informatics resources for MS-based proteomics

  2023cites this paper
• Cancer Serum Atlas-Supported Precise Pan-Targeted Proteomics Enable Multicancer Detection.

  2022cites this paper
• Proteomics in thrombosis research

  2022cites this paper
• Quantitative Cell Proteomic Atlas: Pathway-scale targeted mass spectrometry for high-resolution functional profiling of cell signaling

  2022cites this paper
• Needler: An Algorithm to Develop a Comprehensive Targeted MS Method Capable of Monitoring the Human Proteome

  2022cites this paper
• Advanced mass spectrometry-based methods for protein molecular-structural biologists

  2022cites this paper
• A single protein to multiple peptides: Investigation of protein-peptide relationship using targeted alpha-2-macroglobulin analysis

  2022cites this paper
• Modeling clinical phenotype variability: consideration of genomic variations, computational methods, and quantitative proteomics.

  2022cites this paper
• Fungal resilience and host–pathogen interactions: Future perspectives and opportunities

  2022cites this paper
• Rational Design and Development of SARS-CoV-2 Serological Diagnostics by Immunoprecipitation-Targeted Proteomics

  2022cites this paper
• Typic: A Practical and Robust Tool to Rank Proteotypic Peptides for Targeted Proteomics.

  2022cites this paper
• Clinical applications of plasma proteomics and peptidomics: Towards precision medicine

  2022cites this paper
• Deep proteomic dataset of human liver samples obtained by two-dimensional sample fractionation coupled with tandem mass spectrometry

  2022cites this paper
• Internal Standard Triggered-Parallel Reaction Monitoring Mass Spectrometry Enables Multiplexed Quantification of Candidate Biomarkers in Plasma

  2022cites this paper
• Laboratory Techniques in Cellular and Molecular Medicine

  2022cites this paper
• Quantitative Detection of Protein Splice Variants by Selected Reaction Monitoring (SRM) Mass Spectrometry.

  2022cites this paper
• The metabolomic landscape plays a critical role in glioma oncogenesis

  2022cites this paper
• Circulating proteomic panels for risk stratification of intracranial aneurysm and its rupture

  2022cites this paper
• Is There a Need for a More Precise Description of Biomolecule Interactions to Understand Cell Function?

  2022cites this paper
• Cancer Serum Atlas supported precise pan-targeted proteomics enable multi-cancer detection

  2022influential citation
• A large‐scale targeted proteomics of plasma extracellular vesicles shows utility for prognosis prediction subtyping in colorectal cancer

  2022cites this paper
• Lung proteomic biomarkers associated with chronic obstructive pulmonary disease

  2021cites this paper
• SUMOylation controls the binding of hexokinase 2 to mitochondria and protects against prostate cancer tumorigenesis

  2021cites this paper
• Immunoprecipitation-targeted proteomics assays facilitate rational development of SARS-CoV-2 serological diagnostics

  2021cites this paper
• An Introduction to Advanced Targeted Acquisition Methods

  2021influential citation
• Peptide barcoding for one-pot evaluation of sequence–function relationships of nanobodies

  2021cites this paper
• Targeted Selected Reaction Monitoring Verifies Histology Specific Peptide Signatures in Epithelial Ovarian Cancer

  2021cites this paper
• Multiplexed triage of candidate biomarkers in plasma using internal standard triggered-parallel reaction monitoring mass spectrometry

  2021cites this paper
• Targeted liquid chromatography‐tandem mass spectrometry analysis of proteins: Basic principles, applications, and perspectives

  2021cites this paper
• Proteomics in the pharmaceutical and biotechnology industry: a look to the next decade

  2021cites this paper
• Toward proteome‐wide exploration of proteins in dried blood spots using liquid chromatography‐coupled mass spectrometry

  2021cites this paper
• Functional analysis of a common BAG3 allele associated with protection from heart failure

  2021cites this paper
• Binding and detoxification ability of lactobacillus acidophilus towards di-n-butyl phthalate: Change of MAPK pathway in Caco-2 cell model.

  2021cites this paper
• Proteomics, Personalized Medicine and Cancer

  2021cites this paper
• Mass spectrometry-based chemical mapping and profiling toward molecular understanding of diseases in precision medicine

  2021cites this paper
• The clinical potential of prm-PASEF mass spectrometry

  2021cites this paper
• Targeted mass-spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP kinase, and AKT signaling

  2021cites this paper
• Multiple Reaction Monitoring-Based Targeted Assays for the Validation of Protein Biomarkers in Brain Tumors

  2021cites this paper
• Mapping Sphingolipid Metabolism Pathways during Phagosomal Maturation.

  2021cites this paper
• Number of detected proteins as the function of the sensitivity of proteomic technology in human liver cells

  2021cites this paper
• The genetic proteome: Using genetics to inform the proteome of mycobacterial pathogens

  2021cites this paper
• Analysis of ovarian cancer cell secretome during epithelial to mesenchymal transition reveals a protein signature associated with advanced stages of ovarian tumors.

  2021cites this paper
• Reflections on the HUPO Human Proteome Project, the Flagship Project of the Human Proteome Organization, at 10 Years

  2021influential citation
• Komplexe Systeme verhalten sich grundsätzlich ähnlich

  2021cites this paper
• High‐Performance Liquid Chromatography–Mass Spectrometry in Peptide and Protein Analysis

  2021cites this paper
• Identification of SARS-CoV-2 Proteins from Nasopharyngeal Swabs Probed by Multiple Reaction Monitoring Tandem Mass Spectrometry

  2021cites this paper
• Monitoring one-carbon metabolism by mass spectrometry to assess liver function and disease

  2021cites this paper
• An Update on MRMAssayDB: A Comprehensive Resource for Targeted Proteomics Assays in the Community

  2021cites this paper
• Collision energies: Optimization strategies for bottom-up proteomics.

  2021cites this paper
• Mass spectrometry-based protein identification in proteomics - a review

  2020cites this paper
• PIKES Analysis Reveals Response to Degraders and Key Regulatory Mechanisms of the CRL4 Network.

  2020cites this paper
• Mass Spectrometry of Human Transporters.

  2020cites this paper
• Hybrid Spectral Library Combining DIA-MS Data and a Targeted Virtual Library Substantially Deepens the Proteome Coverage

  2020cites this paper
• The Wonderful World of Poo: The Turdome and Beyond

  2020cites this paper
• Proteomic Analyses

  2020cites this paper
• Systems biology in cardiovascular disease: a multiomics approach

  2020cites this paper