The Drosophila tamou gene, a component of the activating pathway of extramacrochaetae expression, encodes a protein homologous to mammalian cell-cell junction-associated protein ZO-1.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Genes & Development

• Publication date

  1996-07-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1101/GAD.10.14.1783PMID 8698238
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The C. elegans vulval induction gene lin-2 encodes a member of the MAGUK family of cell junction proteins.

  1996cited by this paper
• Zygotic Drosophila E-cadherin expression is required for processes of dynamic epithelial cell rearrangement in the Drosophila embryo.

  1996cited by this paper
• Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95.

  1995cited by this paper
• Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases

  1995cited by this paper
• Tight junctions, membrane-associated guanylate kinases and cell signaling.

  1995cited by this paper
• Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein

  1995cited by this paper
• Modular binding domains in signal transduction proteins.

  1995cited by this paper
• FAP-1: a protein tyrosine phosphatase that associates with Fas.

  1995cited by this paper
• Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions

  1994cited by this paper
• A Drosophila homolog of cadherin associated with armadillo and essential for embryonic cell-cell adhesion.

  1994cited by this paper
• The Drosophila tumor suppressor gene dlg is required for normal synaptic bouton structure.

  1994cited by this paper
• atonal is the proneural gene for Drosophila photoreceptors

  1994cited by this paper
• Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein

  1994cited by this paper
• Negative regulation of proneural gene activity: hairy is a direct transcriptional repressor of achaete.

  1994cited by this paper
• The expression pattern of Id4, a novel dominant negative helix-loop-helix protein, is distinct from Id1, Id2 and Id3.

  1994cited by this paper
• A novel protein-tyrosine phosphatase with homology to both the cytoskeletal proteins of the band 4.1 family and junction-associated guanylate kinases.

  1994cited by this paper
• The Friedreich ataxia region: characterization of two novel genes and reduction of the critical region to 300 kb.

  1994cited by this paper
• Cloning and characterization of hdlg: the human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1.

  1994cited by this paper
• Hairy function as a DNA-binding helix-loop-helix repressor of Drosophila sensory organ formation.

  1994cited by this paper
• Cell shape and interaction defects in alpha-spectrin mutants of Drosophila melanogaster

  1993cited by this paper
• The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions.

  1993cited by this paper
• Expanded, a negative regulator of cell proliferation in Drosophila, shows homology to the NF2 tumor suppressor.

  1993cited by this paper
• atonal is a proneural gene that directs chordotonal organ formation in the Drosophila peripheral nervous system.

  1993cited by this paper
• pannier, a negative regulator of achaete and scute in Drosophila, encodes a zinc finger protein with homology to the vertebrate transcription factor GATA-1.

  1993cited by this paper
• Sequential emergence of the evenly spaced microchaetes on the notum of Drosophila

  1993cited by this paper
• SAP90, a rat presynaptic protein related to the product of the Drosophila tumor suppressor gene dlg-A.

  1993cited by this paper
• Neuronal expression of regulatory helix-loop-helix factor Id2 gene in mouse.

  1993cited by this paper
• The daughterless gene product in Drosophila is a nuclear protein that is broadly expressed throughout the organism during development.

  1993cited by this paper
• Occludin: a novel integral membrane protein localizing at tight junctions

  1993cited by this paper
• ZO-1, DlgA and PSD-95/SAP90: homologous proteins in tight, septate and synaptic cell junctions.

  1993cited by this paper
• Assembly of the tight junction: the role of diacylglycerol

  1993cited by this paper
• The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy

  1993cited by this paper
• Cell interactions and gene interactions in peripheral neurogenesis.

  1993cited by this paper
• Structural diversity of neuronal nitric oxide synthase mRNA in the nervous system.

  1993cited by this paper
• Cloned human brain nitric oxide synthase is highly expressed in skeletal muscle

  1993cited by this paper
• Refined structure of the complex between guanylate kinase and its substrate GMP at 2.0 A resolution.

  1992cited by this paper
• The gene for the helix-loop-helix protein, Id, is specifically expressed in neural precursors.

  1992cited by this paper
• Overexpression of Id protein inhibits the muscle differentiation program: in vivo association of Id with E2A proteins.

  1992cited by this paper
• Localization and differential expression of two isoforms of the tight junction protein ZO-1.

  1992cited by this paper
• The Drosophila couch potato gene: an essential gene required for normal adult behavior.

  1992cited by this paper
• Spatial regulation of proneural gene activity: auto- and cross-activation of achaete is antagonized by extramacrochaetae.

  1992cited by this paper
• Patterning of the Drosophila nervous system: the achaete-scute gene complex.

  1992cited by this paper
• Id expression during mouse development: A role in morphogenesis

  1992cited by this paper
• The extramacrochaetae gene provides information for sensory organ patterning.

  1992cited by this paper
• The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein.

  1992cited by this paper
• A 220-kD undercoat-constitutive protein: its specific localization at cadherin-based cell-cell adhesion sites

  1991cited by this paper
• Transcriptional activation by heterodimers of the achaete‐scute and daughterless gene products of Drosophila.

  1991cited by this paper
• Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1.

  1991cited by this paper
• Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

  1991cited by this paper
• The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions.

  1991cited by this paper
• The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamily.

  1991cited by this paper
• An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene.

  1991cited by this paper
• Proneural clusters of achaete-scute expression and the generation of sensory organs in the Drosophila imaginal wing disc.

  1991cited by this paper
• Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins

  1991cited by this paper
• Regulation of achaete-scute gene expression and sensory organ pattern formation in the Drosophila wing.

  1991cited by this paper
• The Drosophila extramacrochaetae protein antagonizes sequence-specific DNA binding by daughterless/achaete-scute protein complexes.

  1991cited by this paper
• extramacrochaetae, a negative regulator of sensory organ development in Drosophila, defines a new class of helix-loop-helix proteins.

  1990cited by this paper
• Genes required for specifying cell fates in Drosophila embryonic sensory nervous system.

  1990cited by this paper
• The Drosophila extramacrochaetae locus, an antagonist of proneural genes that, like these genes, encodes a helix-loop-helix protein.

  1990cited by this paper
• The protein Id: a negative regulator of helix-loop-helix DNA binding proteins.

  1990cited by this paper
• A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

  1989cited by this paper
• Genesis of the Drosophila peripheral nervous system.

  1989cited by this paper
• Molecular cloning of the lethal(1)discs large-1 oncogene of Drosophila.

  1989cited by this paper
• Guanylate kinase from Saccharomyces cerevisiae. Isolation and characterization, crystallization and preliminary X-ray analysis, amino acid sequence and comparison with adenylate kinases.

  1989cited by this paper
• Molecular analysis of the asense gene, a member of the achaete‐scute complex of Drosophila melanogaster, and its novel role in optic lobe development.

  1989cited by this paper
• P-element-mediated enhancer detection: an efficient method for isolating and characterizing developmentally regulated genes in Drosophila.

  1989cited by this paper
• The Drosophila hairy protein acts in both segmentation and bristle patterning and shows homology to N‐myc.

  1989cited by this paper
• Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence.

  1989cited by this paper
• Expression of achaete and scute genes in Drosophila imaginal discs and their function in sensory organ development.

  1989cited by this paper
• Molecular characterization of daughterless, a Drosophila sex determination gene with multiple roles in development.

  1988cited by this paper
• The achaete‐scute gene complex of Drosophila melanogaster comprises four homologous genes.

  1988cited by this paper
• daughterless, a Drosophila gene essential for both neurogenesis and sex determination, has sequence similarities to myc and the achaete-scute complex.

  1988cited by this paper
• The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins.

  1988cited by this paper
• The achaete-scute gene complex of D. melanogaster: conserved domains in a subset of genes required for neurogenesis and their homology to myc.

  1987cited by this paper
• Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia

  1986cited by this paper
• Multiple upstream regulatory elements control the expression of the Drosophila white gene.

  1985cited by this paper
• Genetic control of sensory connections in Drosophila

  1980cited by this paper
• The projection of sensory neurons in the central nervous system of Drosophila: choice of the appropriate pathway.

  1980cited by this paper

• DNA-PAINT resolves E-cadherin-independent cross-junctional F-actin organization in Drosophila embryonic tissue.

  2026cites this paper
• Drosophila melanogaster: a simple genetic model of kidney structure, function and disease

  2022cites this paper
• Transcriptomic analysis of feminizing somatic stem cells in the Drosophila testis reveals putative downstream effectors of the transcription factor Chinmo

  2021cites this paper
• The ZO-1 protein Polychaetoid as an upstream regulator of the Hippo pathway in Drosophila

  2021cites this paper
• The Drosophila Afadin and ZO-1 homologues Canoe and Polychaetoid act in parallel to maintain epithelial integrity when challenged by adherens junction remodeling

  2019cites this paper
• ZO‐2, a tight junction protein involved in gene expression, proliferation, apoptosis, and cell size regulation

  2017cites this paper
• The Drosophila ZO-1 protein Polychaetoid suppresses Deltex-regulated Notch activity to modulate germline stem cell niche formation

  2017cites this paper
• Fonctions et régulations des protéines Crumbs dans la morphogenèse des tissus épithéliaux

  2016cites this paper
• Cell migration.

  2012cites this paper
• Drosophila Tel2 Is Expressed as a Translational Fusion with EpsinR and Is a Regulator of Wingless Signaling

  2012cites this paper
• Su(dx) E3 ubiquitin ligase–dependent and –independent functions of Polychaetoid, the Drosophila ZO-1 homologue

  2011cites this paper
• An unconventional role for the septate junctions and Gliotactin in cell division

  2011cites this paper
• ZO Proteins and Redox-Dependent Processes

  2011cites this paper
• The single Drosophila ZO-1 protein Polychaetoid regulates embryonic morphogenesis in coordination with Canoe/afadin and Enabled

  2011influential citation
• The Dual Role of Zonula Occludens (ZO) Proteins

  2010cites this paper
• Sns and Kirre, the Drosophila orthologs of Nephrin and Neph1, direct adhesion, fusion and formation of a slit diaphragm-like structure in insect nephrocytes

  2009cites this paper
• The gene network determining development of Drosophila melanogaster mechanoreceptors

  2009cites this paper
• Tight junctions and the regulation of gene expression.

  2009cites this paper
• The insect nephrocyte is a podocyte-like cell with a filtration slit diaphragm

  2008cites this paper
• Polychaetoid controls patterning by modulating adhesion in the Drosophila pupal retina.

  2008cites this paper
• Epithelial tight junctions, gene expression and nucleo-junctional interplay

  2007cites this paper
• Tight Junctions and the Regulation of Epithelial Cell Proliferation and Gene Expression

  2006cites this paper
• Rap‐GEF/Rap signaling restricts the formation of supernumerary spermathecae in Drosophila melanogaster

  2006cites this paper
• Polychaetoid/ZO-1 is required for cell specification and rearrangement during Drosophila tracheal morphogenesis.

  2006cites this paper
• Genetic and molecular regulation of epithelial tube morphogenesis

  2006cites this paper
• Tight Junction Proteins and Cancer

  2006cites this paper
• MPP3 is recruited to the MPP5 protein scaffold at the retinal outer limiting membrane

  2006cites this paper
• ZO Proteins and Tight Junction Assembly

  2006cites this paper
• Membrane-type 1 matrix metalloproteinase expression is regulated by zonula occludens-1 in human breast cancer cells.

  2005cites this paper
• What is Drosophila Telling Us About Cancer?

  2004cites this paper
• PDZ-containing proteins: alternative splicing as a source of functional diversity.

  2004cites this paper
• BPGAP1 interacts with cortactin and facilitates its translocation to cell periphery for enhanced cell migration.

  2004cites this paper
• Filamentous actin binding ability of cortactin isoforms is responsible for their cell-cell junctional localization in epithelial cells.

  2004cites this paper
• Maintaining epithelial integrity

  2003influential citation
• The Tight Junction Protein ZO-2 Localizes to the Nucleus and Interacts with the Heterogeneous Nuclear Ribonucleoprotein Scaffold Attachment Factor-B*

  2003cites this paper
• The Na+/K+ ATPase is required for septate junction function and epithelial tube-size control in the Drosophila tracheal system

  2003cites this paper
• Epithelial cell adhesion and the regulation of gene expression.

  2003cites this paper
• Signalling to and from tight junctions

  2003cites this paper
• Tight junction proteins.

  2003cites this paper
• Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila.

  2002cites this paper
• Rap1 GTPase Regulation of Adherens Junction Positioning and Cell Adhesion

  2002cites this paper
• The Cytoplasmic Plaque Proteins of the Tight Junction

  2001cites this paper
• Assembly of C. elegans apical junctions involves positioning and compaction by LET-413 and protein aggregation by the MAGUK protein DLG-1.

  2001cites this paper
• PDZ proteins and polarity: functions from the fly.

  2001cites this paper
• Epithelial cell polarity and cell junctions in Drosophila.

  2001cites this paper
• Genomic organization, transcription start sites, and chromosomal location of the Drosophila cortactin gene.

  2001cites this paper
• Localization of the Drosophila MAGUK protein Polychaetoid is controlled by alternative splicing.

  2001influential citation
• Cortactin: coupling membrane dynamics to cortical actin assembly

  2001cites this paper
• Emc, a negative HLH regulator with multiple functions in Drosophila development

  2001influential citation
• Of mice, frogs and flies: Generation of membrane asymmetries in early development

  2001cites this paper
• PII: S0925-4773(00)00550-5

  2001influential citation
• MAGUK proteins: structure and role in the tight junction.

  2000cites this paper
• Genetic control of epithelial cell polarity: Lessons from Drosophila

  2000cites this paper
• Chapter 5 Molecular structure and regulation of tight junctions

  2000cites this paper
• Involvement of the Helix-Loop-Helix Protein Id-1 in the Glucocorticoid Regulation of Tight Junctions in Mammary Epithelial Cells*

  2000cites this paper
• An enhancer trap screen for ecdysone-inducible genes required for Drosophila adult leg morphogenesis.

  2000cites this paper
• The tight junction protein ZO‐1 and an interacting transcription factor regulate ErbB‐2 expression

  2000cites this paper
• The PDZ Domains of Zonula Occludens-1 Induce an Epithelial to Mesenchymal Transition of Madin-Darby Canine Kidney I Cells

  2000cites this paper
• Signaling pathways are focused at specialized regions of the plasma membrane by scaffolding proteins of the MAGUK family.

  1999cites this paper
• Cell polarity: Versatile scaffolds keep things in place.

  1999cites this paper
• Identification of a Homolog of Actin-Binding Protein, ABP-280, Localized at Epithelial Cell-Cell Boundaries in Hydra

  1999cites this paper
• A recessive mutation leading to vertebral ankylosis in zebrafish is associated with amino acid alterations in the homologue of the human membrane-associated guanylate kinase DLG3.

  1999cites this paper
• Role of tight junctions in the occurrence of cancer invasion and metastasis

  1999cites this paper
• Absence of the tight junctional protein AF-6 disrupts epithelial cell-cell junctions and cell polarity during mouse development.

  1999cites this paper
• PDZ domains and the formation of protein networks at the plasma membrane.

  1998cites this paper
• The tight junction: morphology to molecules.

  1998cites this paper
• Direct binding between two PDZ domain proteins Canoe and ZO-1 and their roles in regulation of the jun N-terminal kinase pathway in Drosophila morphogenesis.

  1998cites this paper
• Cortactin Associates with the Cell-Cell Junction Protein ZO-1 in both Drosophila and Mouse*

  1998cites this paper
• ZO-3, a Novel Member of the MAGUK Protein Family Found at the Tight Junction, Interacts with ZO-1 and Occludin

  1998influential citation
• Molecular architecture of tight junctions.

  1998cites this paper
• Organizing a functional junctional complex requires specific domains of the Drosophila MAGUK Discs large.

  1997cites this paper
• Junction genetics.

  1997cites this paper
• Epithelial differentiation in Drosophila

  1997cites this paper