Gender differences in healthy aging and Alzheimer's Dementia: A 18F‐FDG‐PET study of brain and cognitive reserve

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Human Brain Mapping

• Publication date

  2017-05-31

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1002/hbm.23659PMID 28561534PMCID PMC6866811
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2013cited by this paper
• Efficiency, capacity, compensation, maintenance, plasticity: emerging concepts in cognitive reserve.

  2013cited by this paper
• Cholinergic activity correlates with reserve proxies in Alzheimer's disease.

  2013influential reference
• Relationships between brain metabolism decrease in normal aging and changes in structural and functional connectivity

  2013cited by this paper
• Education increases reserve against Alzheimer’s disease—evidence from structural MRI analysis

  2012cited by this paper
• Education, occupation, leisure activities, and brain reserve: a population-based study.

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  2011cited by this paper
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  2011cited by this paper
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  2008influential reference
• Cognition and sex differences

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• Gender differences in brain reserve : an (18)F-FDG PET study in Alzheimer's disease.

  2007influential reference
• Age and gender effects on human brain anatomy: a voxel-based morphometric study in healthy elderly.

  2007cited by this paper
• Adult age differences in the functional neuroanatomy of visual attention: a combined fMRI and DTI study.

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  2004cited by this paper
• Thinning of the cerebral cortex in aging.

  2004influential reference
• Aging, sexual dimorphism, and hemispheric asymmetry of the cerebral cortex: replicability of regional differences in volume.

  2004cited by this paper
• Anterior prefrontal cortex: insights into function from anatomy and neuroimaging

  2004cited by this paper
• Sex differences for selective forms of spatial memory.

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  2004cited by this paper
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  2003cited by this paper
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  2002cited by this paper
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  2002cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  1998cited by this paper
• Selective aging of the human cerebral cortex observed in vivo: differential vulnerability of the prefrontal gray matter.

  1997cited by this paper
• Lifetime risk of dementia and Alzheimer's disease

  1997cited by this paper
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  1996cited by this paper
• Sex differences in aging of the human frontal and temporal lobes

  1994cited by this paper
• Gender differences in age effect on brain atrophy measured by magnetic resonance imaging.

  1991cited by this paper
• Clinical, pathological, and neurochemical changes in dementia: A subgroup with preserved mental status and numerous neocortical plaques

  1988cited by this paper
• Intercorrelations of Glucose Metabolic Rates between Brain Regions: Application to Healthy Males in a State of Reduced Sensory Input

  1984cited by this paper

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