Fusion of Two Immunoglobulin-producing Myeloma Cells

No abstract is available for this paper.

• Publication year

  1973

• Venue

  Nature

• Publication date

  1973-07-06

• Fields of study

  Biology, Chemistry

• Identifiers
  DOI 10.1038/244042A0
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Transplantable immunoglobulin‐secreting tumours in rats. I. General features of LOU/Ws1 strain rat immunocytomas and their monoclonal proteins

  1972cited by this paper
• Biosynthesis of immunoglobulins.

  1972cited by this paper
• Suppression of immunoglobulin synthesis by cellular hybridization.

  1971cited by this paper
• Immunoglobulin G and free kapa-chain synthesis in different clones of a hybrid cell line.

  1971cited by this paper
• IgG Synthesis in Hybrid Cells from an Antibody-producing Mouse Myeloma and an L Cell Substrain

  1970cited by this paper
• The genetic basis of antibody specificity.

  1970cited by this paper
• Mouse myelomas and lymphomas in culture.

  1970cited by this paper
• Isoelectric Focusing in Polyacrylamide Gel and its Application to Immunoglobulins

  1968cited by this paper
• Relationships Between the Heterogeneity of Immunoglobulins and the Differentiation of Plasma Cells

  1967cited by this paper
• Hybrid Cells Derived from Mouse and Man : Artificial Heterokaryons of Mammalian Cells from Different Species

  1965cited by this paper
• Polypeptide Chains of Human Gamma-Globulin: Cellular Localization by Fluorescent Antibody

  1964cited by this paper
• Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed Recombinants

  1964cited by this paper
• THE CELLULAR ORIGIN OF HUMAN IMMUNOGLOBULINS (γ2, γ1M, γ1A)

  1963cited by this paper
• Analysis of giant polynuclear cell formation caused by HVJ virus from Ehrlich's ascites tumor cells. I. Microscopic observation of giant polynuclear cell formation.

  1962cited by this paper

• A Brief Chronicle of Antibody Research and Technological Advances

  2024cites this paper
• New Technologies in Therapeutic Antibody Development: The Next Frontier for Treating Infectious Diseases.

  2024cites this paper
• Epitope mapping of SARS-CoV-2 RBDs by hydroxyl radical protein footprinting reveals the importance of including negative antibody controls

  2023cites this paper
• Monoclonal antibodies: Emergence, present and outlook

  2020cites this paper
• Monoclonal Antibodies for Cancer Immunotherapy

  2020cites this paper
• UNDERSTANDING THE RELATIONSHIP BETWEEN BISPECIFIC ANTIBODY DESIGN AND FUNCTION: HOW VALENCY AND SPATIAL CONFIGURATION CAN IMPROVE ANTI-TUMOR RESPONSES

  2019cites this paper
• Overview of the Immune System and Its Pharmacological Targets

  2019cites this paper
• Les anticorps monoclonaux

  2019cites this paper
• Bispecific antibodies and their potential for cancer immunotherapy

  2017cites this paper
• Chapter 2 Bispecific Antibodies from Hybrid Hybridoma

  2017cites this paper
• The current status of immunotherapy in peritoneal carcinomatosis

  2016cites this paper
• The birth of monoclonal antibodies

  2016cites this paper
• Monoclonal Antibodies for Cancer Immunotherapy

  2015cites this paper
• Monoclonal Antibodies: The Final Proof for Clonal Selection

  2014cites this paper
• Advances in bispecific biotherapeutics for the treatment of cancer.

  2012cites this paper
• Bispecific Antibodies from Hybrid Hybridoma

  2011cites this paper
• Optical excitations in hematite (α-Fe2O3) via embedded cluster models: A CASPT2 study

  2011cites this paper
• The Design and Engineering of IgG-Like Bispecific Antibodies

  2011cites this paper
• Supresión de la angiogénesis tumoral a través de anticuerpos monoclonales

  2010cites this paper
• Engineered Proteins Pull Double Duty

  2010cites this paper
• Evolution of programmed cell fusion: Common mechanisms and distinct functions

  2010cites this paper
• Bispecific antibodies for cancer therapy

  2009cites this paper
• Recent applications of the SCF—Xα scattered—wave method to complex molecules and solids

  2009cites this paper
• The assembly of single domain antibodies into bispecific decavalent molecules.

  2007cites this paper
• Bispecific Antibodies: Molecules That Enable Novel Therapeutic Strategies

  2007cites this paper
• Chromosome segregation and expression of rat immunoglobulins in rat/mouse hybrid myelomas

  2005cites this paper
• César Milstein and the discovery of monoclonal antibodies

  2004cites this paper
• Development and Characterization of Monoclonal Antibodies Directed Against Tanapox Virus

  2004cites this paper
• Bispecific antibody conjugates in therapeutics.

  2003cites this paper
• Fe and Mn K-edge XANES study of ancient Roman glasses

  2002cites this paper
• A human myeloma cell line suitable for the generation of human monoclonal antibodies.

  2001cites this paper
• Structure and Reactivity of Semiconducting Mineral Surfaces: Convergence of Molecular Modeling and Experiment

  2001cites this paper
• Development and Characterization of Monoclonal Antibodies Directed Against Yaba-Like Disease Virus

  2001cites this paper
• Duocalins: Engineered Ligand-Binding Proteins with Dual Specificity Derived from the Lipocalin Fold

  2001cites this paper
• Synthesis of bifunctional antibodies for immunoassays.

  2000cites this paper
• With the benefit of hindsight.

  2000cites this paper
• The hybridoma revolution: an offshoot of basic research.

  1999cites this paper
• Hybridomas, B Cell

  1998cites this paper
• 7 – Introduction to Monoclonal Antibodies

  1996cites this paper
• Solid phase synthesis of bifunctional antibodies.

  1995cites this paper
• Micelle Stabilized Phosphorescent Immunoassay Based on Bispecific Antibodies Against Label and Antigen

  1995cites this paper
• Antibody and cytokine studies related to chronic lymphocytic leukemia

  1994cites this paper
• Concepts of antibody-mediated cancer therapy.

  1993cites this paper
• From the Structure of Antibodies to the Diversification of the Immune Response

  1993cites this paper
• Fe3+Co-ordination Site in α-Fe2O3—An Evaluation of its Electronic Structure

  1992cites this paper
• Bifunctional antibodies and their potential clinical applications

  1992cites this paper
• Bifunctional antibodies: concept, production and applications.

  1990cites this paper
• Antibody-Mediated Cancer Diagnosis and Therapy

  1990cites this paper
• The improved lytic function and in vivo efficacy of monovalent monoclonal CD3 antibodies

  1989cites this paper
• Monoclonal antibodies: production, purification, and technology.

  1989cites this paper
• The photoelectrochemistry of niobium doped α-Fe2O3

  1988cites this paper
• Recent improvements in the production of antibody-secreting hybridoma cells

  1988cites this paper
• The potential of hybrid antibodies secreted by hybrid‐hybridomas in tumour therapy

  1988cites this paper
• Structural Iron in Kaolinites and in Associated Ancillary Minerals

  1988cites this paper
• Xanes study of five-fold coordinated iron (III) in Fe3PO7 and FeAsO4-I

  1988cites this paper
• Hybrid polypeptide heavy chains produced by two hybridoma lines.

  1987cites this paper
• Mechanisms of Cell Fusion and Selection in the Generation of Hybridomas

  1987cites this paper
• Methods of Hybridoma Formation

  1987cites this paper
• CHARACTERIZATION OF THREE MONOCLONAL ANTIBODIES DIRECTED AGAINST A BOVINE CEREBRAL CORTEX CELL SURFACE SIALOGLYCOPEPTIDE

  1987cites this paper
• Production of Monoclonal Antibodies for Radioimmunoassays

  1987cites this paper
• Rat-Rat Hybridoma Formation and Rat Monoclonal Antibodies

  1987cites this paper
• Tolerance to rat monoclonal antibodies. Implications for serotherapy

  1986cites this paper
• Monoclonal Antibodies as Drugs or Devices: Practical and Regulatory Aspects

  1986cites this paper
• [17] Bispecific monoclonal antibodies from hybrid hybridomas

  1986cites this paper
• .- ANTIBODIES AS DRUGS OR DEVICES: PRACTICAL

  1986cites this paper
• From antibody structure to immunological diversification of immune response.

  1986cites this paper
• Human Complement-Fixing Antibodies in Transplantation

  1985cites this paper
• From the structure of antibodies to the diversification of the immune response

  1985cites this paper
• The electronic structures of Fe3+ coordination sites in iron oxides: Applications to spectra, bonding, and magnetism

  1985cites this paper
• From the Structure of Antibodies to the Diversification of the Immune Responce (Noble Lecture)

  1985cites this paper
• Monoclonal antibodies in the study of structure‐function relationships of proteins

  1985cites this paper
• Cluster calculation of electronic structure and hyperfine interactions for α-Fe2O3

  1985cites this paper
• Spectroscopy and Chemical Bonding in the Opaque Minerals

  1985cites this paper
• Von der Antikörperstruktur zur Diversität der Immunantwort (Nobel-Vortrag)†

  1985cites this paper
• Human Hybridomas and Monoclonal Antibodies

  1985cites this paper
• From the Structure of Antibodies to the Diversification of the Immune Response

  1985cites this paper
• Human Hybridomas and Monoclonal Antibodies

  1985cites this paper
• Human Hybridomas and Monoclonal Antibodies The Biology of Cell Fusion

  1985cites this paper
• Production of monoclonal antibody against alkaline phosphatase isolated from mouse lymphoid cell line SJL 46

  1985cites this paper
• Comparison of Poly- and Monoclonal Antibodies for Plasma Determination in Normal Individuals, Patients with Benign Lung Diseases and Patients with Lung Cancer

  1985cites this paper
• Monoclonal Antibody Strategy and Techniques

  1985cites this paper
• Hybrid hybridomas and the production of bi-specific monoclonal antibodies.

  1984cites this paper
• Chromosomal location of immunoglobulin genes: partial mapping of these genes in the rabbit and comparison with Ig genes carrying chromosomes of man and mouse.

  1984cites this paper
• Human monoclonal antibodies: Methods of production and some aspects of their application in oncology

  1984cites this paper
• MRC OX‐19: A monoclonal antibody that labels rat T lymphocytes and augments in vitro proliferative responses

  1984cites this paper
• Induction of immunoglobulin gene expression in mouse fibroblasts by cycloheximide treatment

  1984cites this paper
• Physikalisch-chemische Aspekte immunologischer und anderer reversibler Assoziations-Reaktionen

  1984cites this paper
• Monoclonal antibodies of murine and human origin their generation characterization and use

  1984cites this paper
• Hybrid hybridomas and their use in immunohistochemistry

  1983cites this paper
• Molecular approaches to the nervous system.

  1983cites this paper
• Monoclonal antibodies as probes of reproductive mechanisms.

  1983cites this paper
• X-ray K-edge absorption spectra of Fe minerals and model compounds: Near-edge structure

  1983cites this paper
• Production of monoclonal antibodies to bovine leukocyte cell-surface components.

  1983cites this paper
• Procedures for in Vitro Immunization and Monoclonal Antibody Production

  1983cites this paper
• Theory and methods for immunization in culture and monoclonal antibody production.

  1982cites this paper
• Rat monoclonal antitubulin antibodies derived by using a new nonsecreting rat cell line

  1982cites this paper
• HLA antigen expression at the single cell level on a K562 × B cell hybrid: An analysis with monoclonal antibodies using bacterial binding assays

  1982cites this paper
• Intrasubunit homogeneity in heterogeneous IgM antibodies to the DNP moiety derived from a murine hybridoma cell line.

  1982cites this paper
• Hybridoma technology.

  1982cites this paper
• Human plasmacytoma with an unusual karyotype growing in vitro and producing light-chain immunoglobulin.

  1982cites this paper