Neuroprotective effects of resveratrol against β‐amyloid‐induced neurotoxicity in rat hippocampal neurons: involvement of protein kinase C

No abstract is available for this paper.

• Publication year

  2004

• Venue

  British Journal of Pharmacology

• Publication date

  2004-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/sj.bjp.0705688PMID 15028639PMCID PMC1574264
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Red wine micronutrients as protective agents in Alzheimer-like induced insult.

  2003cited by this paper
• Protective effect of resveratrol on β-amyloid-induced oxidative PC12 cell death ☆

  2003influential reference
• Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death.

  2003cited by this paper
• Effect of trans-resveratrol on signal transduction pathways involved in paclitaxel-induced apoptosis in human neuroblastoma SH-SY5Y cells.

  2003cited by this paper
• Estrogen activates protein kinase C in neurons: role in neuroprotection

  2003cited by this paper
• cDNA microarray and proteomic approaches in the study of brain diseases: focus on schizophrenia and Alzheimer's disease.

  2003cited by this paper
• Potential Mechanism by Which Resveratrol, a Red Wine Constituent, Protects Neurons

  2003cited by this paper
• The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics

  2002cited by this paper
• Amyloid β-peptide (1-42)-induced Oxidative Stress and Neurotoxicity: Implications for Neurodegeneration in Alzheimer's Disease Brain. A Review

  2002cited by this paper
• Resveratrol protects against global cerebral ischemic injury in gerbils.

  2002cited by this paper
• Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats.

  2002influential reference
• Involvement of Protein Kinase C Activation and Cell Survival/ Cell Cycle Genes in Green Tea Polyphenol (−)-Epigallocatechin 3-Gallate Neuroprotective Action*

  2002cited by this paper
• Insulin-like growth factor-1-induced phosphorylation of transcription factor FKHRL1 is mediated by phosphatidylinositol 3-kinase/Akt kinase and role of this pathway in insulin-like growth factor-1-induced survival of cultured hippocampal neurons.

  2002cited by this paper
• Antioxidants induce different phenotypes by a distinct modulation of signal transduction

  2002cited by this paper
• Chronic treatment with trans resveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats.

  2002cited by this paper
• Neuroprotective effect of estradiol and phytoestrogens on MPP+‐induced cytotoxicity in neuronal PC12 cells

  2002cited by this paper
• How Protein Kinase C Activation Protects Nerve Cells from Oxidative Stress-Induced Cell Death

  2001influential reference
• Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms.

  2001cited by this paper
• Protective effects of resveratrol on hydrogen peroxide-induced apoptosis in rat pheochromocytoma (PC12) cells.

  2001cited by this paper
• Resveratrol reduction of infarct size in Long-Evans rats subjected to focal cerebral ischemia.

  2001cited by this paper
• Anti-apoptotic effect of trans-resveratrol on paclitaxel-induced apoptosis in the human neuroblastoma SH-SY5Y cell line.

  2001cited by this paper
• Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent, trans-resveratrol in rats.

  2000cited by this paper
• trans‐Resveratrol Protects Embryonic Mesencephalic Cells from tert‐Butyl Hydroperoxide

  2000cited by this paper
• The Ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by beta-amyloid.

  2000influential reference
• The ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by β‐amyloid

  2000influential reference
• Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide‐related toxicity in cultured hippocampal neurons

  2000influential reference
• Protein kinase C iota protects neural cells against apoptosis induced by amyloid β-peptide

  2000cited by this paper
• Protein kinase C iota protects neural cells against apoptosis induced by amyloid beta-peptide.

  2000cited by this paper
• Bilirubin, formed by activation of heme oxygenase-2, protects neurons against oxidative stress injury.

  1999cited by this paper
• The effects of wine and tobacco consumption on cognitive performance in the elderly: a longitudinal study of relative risk.

  1999cited by this paper
• Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage.

  1999cited by this paper
• Opposing Effects of Protein Kinase C δ and Protein Kinase B α on H2O2-Induced Apoptosis in CHO Cells☆

  1999influential reference
• Resveratrol-induced activation of the mitogen-activated protein kinases, ERK1 and ERK2, in human neuroblastoma SH-SY5Y cells.

  1999cited by this paper
• Prevention of neuronal apoptosis by phorbol ester-induced activation of protein kinase C: blockade of p38 mitogen-activated protein kinase.

  1999cited by this paper
• Opposing effects of protein kinase C delta and protein kinase B alpha on H(2)O(2)-induced apoptosis in CHO cells.

  1999influential reference
• Loss of protein kinase C function induces an apoptotic response

  1998cited by this paper
• Overexpression of Protein Kinase C Isoform but not δ in Human Interleukin-3–Dependent Cells Suppresses Apoptosis and Induces bcl-2 Expression

  1998cited by this paper
• Oxidized lipoproteins may play a role in neuronal cell death in Alzheimer disease.

  1998cited by this paper
• Resveratrol Inhibits Cyclooxygenase-2 Transcription and Activity in Phorbol Ester-treated Human Mammary Epithelial Cells*

  1998cited by this paper
• Overexpression of protein kinase C isoform epsilon but not delta in human interleukin-3-dependent cells suppresses apoptosis and induces bcl-2 expression.

  1998cited by this paper
• Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives.

  1997cited by this paper
• Wine consumption and dementia in the elderly: a prospective community study in the Bordeaux area.

  1997cited by this paper
• Regulation of protein kinase C.

  1997cited by this paper
• Atypical Protein Kinase C ι Protects Human Leukemia Cells against Drug-induced Apoptosis*

  1997influential reference
• Isoenzymes of protein kinase C: differential involvement in apoptosis and pathogenesis.

  1997cited by this paper
• Amelioration of oxidative stress by antioxidants and resveratrol in PC12 cells

  1997cited by this paper
• Proteolytic Activation of Protein Kinase C δ by an ICE/CED 3-like Protease Induces Characteristics of Apoptosis

  1996cited by this paper
• Antioxidant activity of resveratrol in red wine.

  1995cited by this paper
• Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C.

  1992cited by this paper

• Nanotherapeutic smart approaches for combating Alzheimer’s disease and overcoming existing obstacles: A novel eco-friendly green approach

  2025cites this paper
• Design of Polycation-Functionalized Resveratrol Nanocrystals for Intranasal Administration

  2025cites this paper
• In Vitro Protective Effects of Resveratrol-Loaded Pluronic Micelles Against Hydrogen Peroxide-Induced Oxidative Damage in U87MG Glioblastoma Cells

  2025cites this paper
• Targeting JNK3 for Alzheimer's disease: Design and synthesis of novel inhibitors with aryl group diversity utilizing wide pocket.

  2025cites this paper
• Emerging nano-derived therapy for the treatment of dementia: a comprehensive review

  2025cites this paper
• Resveratrol Mitigates Inflammation by Modulating Tumor Necrosis Factor-Alpha Receptors (TNFRs) in a 2,4,6-Trinitrobenzene Sulfonic Acid (TNBS)-Induced Rat Model of Colitis

  2025cites this paper
• Biomimetic cell membrane vesicles as promising delivery carriers for dietary polyphenols in neurodegenerative diseases

  2024cites this paper
• MicroRNA in the Exosomes Mediated by Resveratrol to Activate Neuronal Cells

  2024cites this paper
• Unveiling the Involvement of Herpes Simplex Virus-1 in Alzheimer’s Disease: Possible Mechanisms and Therapeutic Implications

  2024cites this paper
• Resveratrol: Protective Agent Against Alzheimer's Disease.

  2024cites this paper
• Angiopep-2 conjugated biomimetic nano-delivery system loaded with resveratrol for the treatment of methamphetamine addiction.

  2024cites this paper
• Comparative analysis of the evolution of phenolic profiles during wood aging of a Carménère wine using novel products or procedures aimed at re-using oak barrels

  2024cites this paper
• Stilbenes, a Versatile Class of Natural Metabolites for Inflammation—An Overview

  2023cites this paper
• Improvement of Caciotta-like cheese nutritional value by means of enrichment with blackcurrant (Ribes nigrum) and Cornelian cherry (Cornus mas)

  2023cites this paper
• The regulatory role of non-coding RNAs and their interactions with phytochemicals in neurodegenerative diseases: a systematic review.

  2023cites this paper
• Current Advances in Mitochondrial Targeted Interventions in Alzheimer’s Disease

  2023cites this paper
• Intranasal in situ gelling liquid crystal for delivery of resveratrol ameliorates memory and neuroinflammation in Alzheimer's disease.

  2023cites this paper
• Resveratrol attenuates N-methyl-D-aspartate receptor-mediated activation in substantia gelatinosa neurons of trigeminal subnucleus caudalis in mice

  2023cites this paper
• Neurotransmitters in Type 2 Diabetes and the Control of Systemic and Central Energy Balance

  2023cites this paper
• Neuroprotective potentials of Lead phytochemicals against Alzheimer's disease with focus on oxidative stress-mediated signaling pathways: Pharmacokinetic challenges, target specificity, clinical trials and future perspectives.

  2023cites this paper
• Carbamate JNK3 Inhibitors Show Promise as Effective Treatments for Alzheimer's Disease: In Vivo Studies on Mouse Models.

  2023cites this paper
• The role of Wnt/mTOR signaling in spinal cord injury.

  2022cites this paper
• Potential implications of polyphenolic compounds in neurodegenerative diseases

  2022cites this paper
• Discovery of novel imidazole chemotypes as isoform-selective JNK3 inhibitors for the treatment of Alzheimer's disease.

  2022cites this paper
• Screening neuroprotective compounds in herpes-induced Alzheimer's disease cell and 3D tissue models.

  2022cites this paper
• Nutrition in Brain Aging: Its Relevance to Age-Associated Neurodegeneration

  2022cites this paper
• Antioxidant Intervention to Improve Cognition in the Aging Brain: The Example of Hydroxytyrosol and Resveratrol

  2022cites this paper
• Neurohormetic phytochemicals in the pathogenesis of neurodegenerative diseases

  2022cites this paper
• Neuroprotective Effects of Resveratrol in In vivo and In vitro Experimental Models of Parkinson’s Disease: a Systematic Review

  2022cites this paper
• Role of Sirtuins in Physiology and Diseases of the Central Nervous System

  2022cites this paper
• Unveiling the Potential of Polyphenols as Anti-Amyloid Molecules in Alzheimer’s Disease

  2022cites this paper
• Role of Phenolic Compounds in Human Disease: Current Knowledge and Future Prospects

  2021cites this paper
• Effects of Quercetin and Resveratrol on Zinc Chloride- and Sodium Metavanadate-Induced Passive Avoidance Memory Retention Deficits in Male Mice

  2021cites this paper
• mTOR pathway: A potential therapeutic target for spinal cord injury.

  2021cites this paper
• Role of nutraceuticals on neurodegenerative diseases: neuroprotective and immunomodulant activity

  2021cites this paper
• Evaluation of Amyloid Polypeptide Aggregation Inhibition and Disaggregation Activity of A-Type Procyanidins

  2021cites this paper
• Resveratrol noncompetitively inhibits glycine receptor-mediated currents in neurons of rat central auditory neurons.

  2021cites this paper
• RRY Inhibits Amyloid-β1–42 Peptide Aggregation and Neurotoxicity

  2021cites this paper
• The Protective Mechanism of SIRT1 in the Regulation of Mitochondrial Biogenesis and Mitochondrial Autophagy in Alzheimer’s Disease

  2021cites this paper
• Protein Kinase C Involvement in Neuroprotective Effects of Thymol and Carvacrol Against Toxicity Induced by Amyloid-β in Rat Hippocampal Neurons

  2021cites this paper
• Potential neuroprotective of trans-resveratrol a promising agent tempeh and soybean seed coats-derived against beta-amyloid neurotoxicity on primary culture of nerve cells induced by 2-methoxyethanol.

  2021cites this paper
• Title: Protein Kinase C Involvement in Neuroprotective Effects of Thymol and Carvacrol Against Toxicity Induced by Amyloid-Β in Rat Hippocampal Neurons Running Title: Effects of thymol and carvacrol on PKC activity

  2021cites this paper
• The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer's disease pathology: from antioxidant to epigenetic therapy.

  2021cites this paper
• NHE6-Depletion Corrects ApoE4-Mediated Synaptic Impairments and Reduces Amyloid Plaque Load

  2021cites this paper
• Molecular simulation probes the potency of resveratrol in regulating the toxic aggregation of mutant V30M TTR fibrils in Transthyretin mediated amyloidosis.

  2021cites this paper
• Nutraceuticals and Functional Foods in Aging and Aging-Associated Diseases

  2021cites this paper
• Resveratrol Delivery from Implanted Cyclodextrin Polymers Provides Sustained Antioxidant Effect on Implanted Neural Probes

  2020cites this paper
• Application of Differentiated SH-SY5Y Cells for Toxicological Studies of Alzheimer's Amyloid Beta Peptide

  2020cites this paper
• Exploring the Promise of Targeting Ubiquitin-Proteasome System to Combat Alzheimer’s Disease

  2020cites this paper
• Neuroprotective Effects of Triterpenoids from Camellia japonica against Amyloid β-Induced Neuronal Damage.

  2020cites this paper
• Protein Kinase C Isozymes and Autophagy during Neurodegenerative Disease Progression

  2020cites this paper
• Resveratrol and Neuroprotection: Impact and Its Therapeutic Potential in Alzheimer's Disease

  2020cites this paper
• The uses of resveratrol for neurological diseases treatment and insights for nanotechnology based-drug delivery systems.

  2020cites this paper
• Anchoring resveratrol on surface of electrospun star-shaped PCL-COOH/PLLA fibers

  2020cites this paper
• New Directions in the Management of Status Epilepticus

  2019cites this paper
• Toxicity of Amyloid-β Peptides Varies Depending on Differentiation Route of SH-SY5Y Cells

  2019cites this paper
• Protective effect of gallic acid against arsenic-induced anxiety−/depression- like behaviors and memory impairment in male rats

  2019cites this paper
• Herpes simplex virus type 1 and Alzheimer’s disease: link and potential impact on treatment

  2019cites this paper
• Review about the multi-target profile of resveratrol and its implication in the SGK1 inhibition.

  2019cites this paper
• Tempeh & Soybean Seed Coat: The Alternative Sources of Trans-Resveratrol as Neuroprotective Agents

  2019cites this paper
• The role of resveratrol in cellular aging

  2019cites this paper
• Advancement in the Pathophysiology of Cerebral Stroke

  2019cites this paper
• Neuroprotective Potential of Small Molecule Phytochemicals in Stroke Therapy

  2019cites this paper
• Resveratrol Regulates BDNF, trkB, PSA-NCAM, and Arc Expression in the Rat Cerebral Cortex after Bilateral Common Carotid Artery Occlusion and Reperfusion

  2019cites this paper
• Herbal Beverages and Brain Function in Health and Disease

  2019cites this paper
• Inhibition of Amyloid Fibrillation by Small Molecules and Nanomaterials: Strategic Development of Pharmaceuticals Against Amyloidosis.

  2019cites this paper
• Shaping the Nrf2-ARE-related pathways in Alzheimer's and Parkinson's diseases.

  2019cites this paper
• Context-sensitive network analysis identifies food metabolites associated with Alzheimer’s disease: an exploratory study

  2019cites this paper
• A Natural Benzofuran from the Patagonic Aleurodiscus vitellinus Fungus has Potent Neuroprotective Properties on a Cellular Model of Amyloid-β Peptide Toxicity

  2018cites this paper
• Combinatorial Preconditioning of Rat Brain Cultures with Subprotective Ethanol and Resveratrol Concentrations Promotes Synergistic Neuroprotection

  2018cites this paper
• Aggregation Modulators Interfere with Membrane Interactions of b 2-Microglobulin Fibrils

  2018cites this paper
• Neuroprotective Effects and Mechanisms of Tea Bioactive Components in Neurodegenerative Diseases

  2018cites this paper
• Resveratrol and Depression in Animal Models: A Systematic Review of the Biological Mechanisms

  2018cites this paper
• SIRT1 facilitates amyloid beta peptide degradation by upregulating lysosome number in primary astrocytes

  2018cites this paper
• Preventive Effects of Resveratrol on Endocannabinoid System and Synaptic Protein Modifications in Rat Cerebral Cortex Challenged by Bilateral Common Carotid Artery Occlusion and Reperfusion

  2018cites this paper
• Phenolic Compounds Characteristic of the Mediterranean Diet in Mitigating Microglia-Mediated Neuroinflammation

  2018cites this paper
• Protein kinase C ‐activating isophthalate derivatives mitigate Alzheimer's disease‐related cellular alterations

  2018cites this paper
• Natural Compounds and Their Derivatives as Multifunctional Agents for the Treatment of Alzheimer Disease

  2018cites this paper
• A Systematic Review on Natural Antioxidant Properties of Resveratrol

  2018cites this paper
• Protective effects of Vitis vinifera (grapes) and one of its biologically active constituents, resveratrol, against natural and chemical toxicities: A comprehensive review

  2018cites this paper
• Recent Status of Nanomaterial Fabrication and Their Potential Applications in Neurological Disease Management

  2018cites this paper
• Resveratrol ameliorates prenatal progestin exposure-induced autism-like behavior through ERβ activation

  2018cites this paper
• Resveratrol Brain Delivery for Neurological Disorders Prevention and Treatment

  2018cites this paper
• Resveratrol, pterostilbene, and dementia

  2018cites this paper
• Pro-Inflammatory Stimuli Influence Expression of Intercellular Adhesion Molecule 1 in Human Anulus Fibrosus Cells through FAK/ERK/GSK3 and PKCδ Signaling Pathways

  2018cites this paper
• Molecular Mechanisms Involved in the Neuroprotective Action of Phytochemicals

  2017cites this paper
• A Combination of Resveratrol and Curcumin is Effective Against Aluminum Chloride-Induced Neuroinflammation in Rats

  2017cites this paper
• Secondary Prevention of Alzheimer’s Disease

  2017cites this paper
• A maternal high-fat diet during pregnancy and lactation, in addition to a postnatal high-fat diet, leads to metabolic syndrome with spatial learning and memory deficits: beneficial effects of resveratrol

  2017cites this paper
• Resveratrol activation of AMPK‐dependent pathways is neuroprotective in human neural stem cells against amyloid‐beta‐induced inflammation and oxidative stress

  2017cites this paper
• Potential benefits of phytochemicals against Alzheimer's disease

  2017cites this paper
• supplementation in the regulation of structural and functional central nervous system disorders among patients with Down syndrome

  2017cites this paper
• Mechanistic comparison of current pharmacological treatments and novel phytochemicals to target amyloid peptides in Alzheimer’s and neurodegenerative diseases

  2017cites this paper
• Resveratrol for Easing Status Epilepticus Induced Brain Injury, Inflammation, Epileptogenesis, and Cognitive and Memory Dysfunction—Are We There Yet?

  2017cites this paper
• Bacoside-A, an Indian Traditional-Medicine Substance, Inhibits β-Amyloid Cytotoxicity, Fibrillation, and Membrane Interactions.

  2017cites this paper
• Phytochemicals Effects on Neurodegenerative Diseases

  2017cites this paper
• Effects of Resveratrol on Cognitive Functions

  2017cites this paper
• Resveratrol ameliorates spatial learning memory impairment induced by Aβ1-42 in rats.

  2017influential citation
• Treatment of Alzheimer Disease with Phytochemicals Other Than Curcumin

  2016cites this paper
• Aflatoxins in Natural Peanuts (Arachis hypogaea L.) of Mexico: Validationof the Biochemical Methods for Extraction and Quantification

  2016cites this paper