Empirical genomewide significance levels established by whole genome simulations

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Genetic Epidemiology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/(SICI)1098-2272(1997)14:3<223::AID-GEPI1>3.0.CO;2-6PMID 9181352
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Age-adjusted recurrence risks for relatives of patients with multiple sclerosis.

  1996cited by this paper
• A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22

  1996cited by this paper
• Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

  1995cited by this paper
• Efficiency of typing unaffected relatives in an affected-sib-pair linkage study with single-locus and multiple tightly linked markers.

  1995cited by this paper
• Surveying multiple sclerosis in the United Kingdom.

  1995cited by this paper
• Complete multipoint sib-pair analysis of qualitative and quantitative traits.

  1995cited by this paper
• Chromosome–specific microsatellite sets for fluorescence–based, semi–automated genome mapping

  1994cited by this paper
• Asymptotic properties of affected-sib-pair linkage analysis.

  1993cited by this paper

• Enhancing testing efficacy of high-density SNP microarrays to distinguish pedigrees belonging to the same kinship class.

  2024cites this paper
• Analysis of convergence of linkage and association studies in autism spectrum disorders

  2023cites this paper
• On the use of dense sets of SNP markers and their potential in relationship inference.

  2019cites this paper
• The genetics of osteoporosis.

  2015cites this paper
• Recherche de nouveaux facteurs génétiques de susceptibilité à la spondyloarthrite grâce à une approche associant études familiales et génomique fonctionnelle

  2014cites this paper
• Cytochrome P450 gene CYP337 and heritability of fitness traits in the Glanville fritillary butterfly

  2014cites this paper
• Statistics in Human Genetics ‐ Further Developments

  2014cites this paper
• Autosomal linkage scan for loci predisposing to comorbid dependence on multiple substances

  2012cites this paper
• Model-Dependent Versus Model-Free Versus Nonparametric Tests

  2012cites this paper
• Population-based linkage analysis of schizophrenia and bipolar case–control cohorts identifies a potential susceptibility locus on 19q13

  2010cites this paper
• 4 - Genetics of Susceptibility and Resistance to Infection

  2010cites this paper
• A genome wide linkage scan for dizygotic twinning in 525 families of mothers of dizygotic twins.

  2010cites this paper
• Models and Methods for Genetic Linkage and Association Analyses.

  2010cites this paper
• Genomic Convergence of Genome‐wide Investigations for Complex Traits

  2009cites this paper
• Sex-specific effect of IL9 polymorphisms on lung function and polysensitization

  2009cites this paper
• Genome‐wide linkage of cotinine pharmacokinetics suggests candidate regions on chromosomes 9 and 11

  2009cites this paper
• A note on permutation tests for genetic association analysis of quantitative traits when variances are heterogeneous

  2009cites this paper
• Heritability and Linkage Analysis of Appendicitis Utilizing Age at Onset

  2009cites this paper
• Noncoding mutations of HGF are associated with nonsyndromic hearing loss, DFNB39.

  2009cites this paper
• Latent variable models in statistical genetics

  2009cites this paper
• Genome‐wide linkage scans for type 2 diabetes mellitus in four ethnically diverse populations—significant evidence for linkage on chromosome 4q in African Americans: the Family Investigation of Nephropathy and Diabetes Research Group

  2009cites this paper
• Allelic Heterogeneity in Genetic Association Meta-Analysis: An Application to DTNBP1 and Schizophrenia

  2009cites this paper
• Linkage analysis of schizophrenia in African-American families.

  2009cites this paper
• Molecular Genetics of Addiction and Related Heritable Phenotypes

  2008cites this paper
• Genetic studies of bipolar disorder and recurrent major depression in a large Scottish family

  2008cites this paper
• Polymorphisms in 9q32 and TSCOT are linked to cervical cancer in affected sib-pairs with high mean age at diagnosis

  2008influential citation
• Identification of a chromosome 8p locus for early-onset coronary heart disease in a French Canadian population

  2008cites this paper
• Linkage on chromosome 14 in a genome-wide linkage study of a broad anxiety phenotype

  2008cites this paper
• Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 401 Genetic Studies of Alzheimer ' s Disease

  2008cites this paper
• Genome-wide high-density SNP-based linkage analysis of infantile hypertrophic pyloric stenosis identifies loci on chromosomes 11q14-q22 and Xq23.

  2008cites this paper
• LOOKING FOR ARTHRITIS REGULATING GENES ON MOUSE CHROMOSOME 6 & 14

  2008cites this paper
• Genetic Studies of Alzheimer's Disease

  2008cites this paper
• "No thanks, it keeps me awake": the genetics of coffee-attributed sleep disturbance.

  2007cites this paper
• Follow‐up mapping supports the evidence for linkage in the candidate region at 9q22 in the NIMH Alzheimer's disease Genetics Initiative cohort

  2007influential citation
• Genetic predisposition to self-curing infection with the protozoan Leishmania chagasi: a genomewide scan.

  2007cites this paper
• Genetic Determination of Osteoporosis: Lessons Learned from a Large Genome-Wide Linkage Study

  2007cites this paper
• Multiple Significance Testing in Genetic Epidemiology

  2006cites this paper
• Relative contribution of genetic and nongenetic modifiers to intestinal obstruction in cystic fibrosis.

  2006cites this paper
• An evaluation of the replicate pool method: quick estimation of genome‐wide linkage peak p‐values

  2006cites this paper
• Identification of susceptibility loci for cervical carcinoma by genome scan of affected sib-pairs.

  2006cites this paper
• Large‐Scale Genome‐Wide Linkage Analysis for Loci Linked to BMD at Different Skeletal Sites in Extreme Selected Sibships

  2006cites this paper
• Genetic studies of stroke in Northern Sweden

  2006cites this paper
• Human Genetics, Statistics in—II

  2006cites this paper
• Idiopathic pulmonary fibrosis : from epidemiology to gene mapping

  2006cites this paper
• Exploration of the Genetic Architecture of Idiopathic Generalized Epilepsies

  2006cites this paper
• Genome-Wide Scan for Hypertension in Sydney Sibships: The GENIHUSS Study

  2005cites this paper
• Genome-wide and Ordered-Subset linkage analyses provide support for autism loci on 17q and 19p with evidence of phenotypic and interlocus genetic correlates

  2005influential citation
• Genome-wide scan for hypertension in Sydney Sibships: the GENIHUSS study.

  2005cites this paper
• Genomewide significant linkage to migrainous headache on chromosome 5q21.

  2005cites this paper
• Robust estimation of critical values for genome scans to detect linkage

  2005influential citation
• Genome screen in the French EGEA study: detection of linked regions shared or not shared by allergic rhinitis and asthma

  2005cites this paper
• Genetic linkage studies.

  2005cites this paper
• Genetic mapping and association analysis in multiple sclerosis

  2005cites this paper
• Mapping complex disease phenotypes

  2005cites this paper
• Search for Susceptibility Genes in Autism Spectrum Disorders

  2005cites this paper
• Genetic and phenotypic dissection of autism susceptibility

  2005cites this paper
• Genome screen in the French EGEA study: detection of

  2005cites this paper
• Mapping complex disease loci in whole-genome association studies

  2004cites this paper
• From families to chromosomes: genetic linkage and association studies for finding cancerpredisposition genes

  2004cites this paper
• The complex genetic epidemiology of prostate cancer.

  2004cites this paper
• Assessing genomewide statistical significance in linkage studies

  2004cites this paper
• Dense genome-wide linkage analysis of rheumatoid arthritis, including covariates.

  2004cites this paper
• Where are the prostate cancer genes?—A summary of eight genome wide searches

  2003cites this paper
• A whole genome screen for linkage in Turkish multiple sclerosis.

  2003cites this paper
• Establishing appropriate genome-wide significance levels for canine linkage analyses.

  2003cites this paper
• Results of a genome‐wide linkage analysis in prostate cancer families ascertained through the ACTANE consortium

  2003cites this paper
• Human genetics of common mycobacterial infections

  2003cites this paper
• Evaluating the results of genomewide linkage scans of complex traits by locus counting.

  2002cites this paper
• Genetics of Multiple Sclerosis

  2002cites this paper
• A genome screen for linkage in Australian sibling-pairs with multiple sclerosis

  2002cites this paper
• Meta-analysis of genetic-linkage analysis of quantitative-trait loci.

  2002influential citation
• Nonparametric Linkage Analysis

  2002cites this paper
• A schizophrenia-susceptibility locus at 6q25, in one of the world's largest reported pedigrees.

  2001cites this paper
• Genome-wide scan in a nationwide study sample of schizophrenia families in Finland reveals susceptibility loci on chromosomes 2q and 5q.

  2001cites this paper
• A chromosome 15 quantitative trait locus controls levels of radiation-induced jejunal crypt cell apoptosis in mice.

  2001cites this paper
• Likelihood‐ratio affected sib‐pair tests applied to multiply affected sibships: Issues of power and type I error rate

  2001cites this paper
• A genome screen for multiple sclerosis in Sardinian multiplex families

  2001cites this paper
• A confidence-set approach for finding tightly linked genomic regions.

  2001influential citation
• Assessing Linkage of Immunoglobulin E Using a Meta‐Analysis Approach

  2001cites this paper
• Model‐Free Tests for Genetic Linkage

  2001cites this paper
• Model‐Free Tests for Genetic Linkage

  2001cites this paper
• A single, sequential, genome‐wide test to identify simultaneously all promising areas in a linkage scan

  2000cites this paper
• Linkage and association of tumor necrosis factor receptor 2 locus with hypertension, hypercholesterolemia and plasma shed receptor.

  2000cites this paper
• Genetic studies of osteoporosis

  1999cites this paper
• On the assessment of statistical significance in disease-gene discovery.

  1999influential citation
• Comparison of variance components and sibpair‐based approaches to quantitative trait linkage analysis in unselected samples

  1999cites this paper
• On a randomization procedure in linkage analysis.

  1999cites this paper
• Linkage and association analysis of susceptibility regions on chromosomes 5 and 6 in 106 Scandinavian sibling pair families with multiple sclerosis

  1999cites this paper
• Suggestive Linkage of the Parathyroid Receptor Type 1 to Osteoporosis

  1999cites this paper
• Inheritance of susceptibility to multiple sclerosis.

  1998cites this paper
• Genetic studies of common rheumatological diseases.

  1998cites this paper
• A genome-wide search for schizophrenia susceptibility genes.

  1998cites this paper
• Linkage thresholds for two-stage genome scans.

  1998cites this paper
• The isolation and characterisation of cosmid-derived canine microsatellite DNA sequences

  1998cites this paper
• Linkage of circulating eosinophils to markers on chromosome 5q.

  1998influential citation
• Response to Kruglyak

  1998cites this paper
• A full genome screen for autism with evidence for linkage to a region on chromosome 7q. International Molecular Genetic Study of Autism Consortium.

  1998cites this paper
• STATISTICAL GENETICS ’98 Methods of Linkage Analysis—and the Assumptions Underlying Them

  1998cites this paper
• The genetics of multiple sclerosis: principles, background and updated results of the United Kingdom systematic genome screen.

  1998cites this paper
• Methods of linkage analysis--and the assumptions underlying them [see comment].

  1998cites this paper