Genetic manipulation of schistosomes – progress with integration competent vectors

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Parasitology

• Publication date

  2011-08-19

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1017/S003118201100134XPMID 21854676PMCID PMC3714224
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Selectable genetic markers for nematode transgenesis

  2011cited by this paper
• Recombinase-mediated cassette exchange (RMCE): traditional concepts and current challenges.

  2011cited by this paper
• Gene deletion from Plasmodium falciparum using FLP and Cre recombinases: implications for applied site-specific recombination.

  2011cited by this paper
• The catalytic domain of all eukaryotic cut-and-paste transposase superfamilies

  2011cited by this paper
• Schistosoma mansoni U6 gene promoter-driven short hairpin RNA induces RNA interference in human fibrosarcoma cells and schistosomules.

  2011cited by this paper
• Establishing Transgenic Schistosomes

  2011influential reference
• Quantitative retrotransposon anchored PCR confirms transduction efficiency of transgenes in adult Schistosoma mansoni.

  2011influential reference
• Progress with schistosome transgenesis.

  2011cited by this paper
• Advances in synthetic siRNA delivery.

  2010cited by this paper
• Selective gene silencing by viral delivery of short hairpin RNA

  2010cited by this paper
• A method for rapid genetic integration into Plasmodium falciparum utilizing mycobacteriophage Bxb1 integrase.

  2010cited by this paper
• Rapid selection of transgenic C. elegans using antibiotic resistance

  2010cited by this paper
• Animal Models for Infectious Diseases

  2010cited by this paper
• RNA Interference in Schistosoma mansoni Schistosomula: Selectivity, Sensitivity and Operation for Larger-Scale Screening

  2010cited by this paper
• A transposon toolkit for gene transfer and mutagenesis in protozoan parasites

  2010cited by this paper
• Gene therapy strategies for hemophilia: benefits versus risks

  2010cited by this paper
• Echinococcus multilocularis primary cells: improved isolation, small-scale cultivation and RNA interference.

  2010influential reference
• Electroporation Facilitates Introduction of Reporter Transgenes and Virions into Schistosome Eggs

  2010cited by this paper
• Viral vector-mediated RNA interference.

  2010cited by this paper
• Biolistic transformation of Schistosoma mansoni: Studies with modified reporter-gene constructs containing regulatory regions of protease genes.

  2010cited by this paper
• Cellular and molecular dissection of pluripotent adult somatic stem cells in planarians

  2010cited by this paper
• Transduction of Schistosoma japonicum schistosomules with vesicular stomatitis virus glycoprotein pseudotyped murine leukemia retrovirus and expression of reporter human telomerase reverse transcriptase in the transgenic schistosomes.

  2010cited by this paper
• A role for host–parasite interactions in the horizontal transfer of transposons across phyla

  2010cited by this paper
• Vector-based RNA interference of cathepsin B1 in Schistosoma mansoni

  2010cited by this paper
• Rhomboid 4 (ROM4) Affects the Processing of Surface Adhesins and Facilitates Host Cell Invasion by Toxoplasma gondii

  2010cited by this paper
• The embryonic development of Schistosoma mansoni eggs: proposal for a new staging system

  2009cited by this paper
• The role of tegumental aquaporin from the human parasitic worm, Schistosoma monsoni, in osmoregulation and drug uptake

  2009cited by this paper
• The Schistosoma japonicum genome reveals features of host–parasite interplay

  2009cited by this paper
• RNA interference targeting leucine aminopeptidase blocks hatching of Schistosoma mansoni eggs.

  2009cited by this paper
• Human cellular restriction factors that target HIV-1 replication

  2009cited by this paper
• RNA interference in schistosomes: machinery and methodology

  2009cited by this paper
• BMC Microbiology BioMed Central Methodology article Short hairpin RNA-mediated knockdown of protein expression in

  2009cited by this paper
• The genome of the blood fluke Schistosoma mansoni

  2009cited by this paper
• A Phenotypic Profile of the Candida albicans Regulatory Network

  2009cited by this paper
• Transposon-mediated genome manipulation in vertebrates

  2009cited by this paper
• Helminth Genomics: The Implications for Human Health

  2009cited by this paper
• Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants.

  2009cited by this paper
• Schistosoma genomics: new perspectives on schistosome biology and host-parasite interaction.

  2009cited by this paper
• Culture for genetic manipulation of developmental stages of Schistosoma mansoni

  2009cited by this paper
• Peroxiredoxin-1 from Schistosoma japonicum functions as a scavenger against hydrogen peroxide but not nitric oxide.

  2009cited by this paper
• Phenotypic Screen of Early-Developing Larvae of the Blood Fluke, Schistosoma mansoni, using RNA Interference

  2009cited by this paper
• Schistosoma japonicum: inhibition of Mago nashi gene expression by shRNA-mediated RNA interference.

  2008cited by this paper
• The Malaria Secretome: From Algorithms to Essential Function in Blood Stage Infection

  2008cited by this paper
• The art and design of genetic screens: RNA interference

  2008cited by this paper
• Integration of reporter transgenes into Schistosoma mansoni chromosomes mediated by pseudotyped murine leukemia virus

  2008cited by this paper
• Development of Functional Genomic Tools in Trematodes: RNA Interference and Luciferase Reporter Gene Activity in Fasciola hepatica

  2008cited by this paper
• RNA interference of Schistosoma mansoni cathepsin D, the apical enzyme of the hemoglobin proteolysis cascade.

  2008cited by this paper
• Helminth infections: the great neglected tropical diseases.

  2008cited by this paper
• Recombinases and their use in gene activation, gene inactivation, and transgenesis.

  2008cited by this paper
• Host factors involved in resistance to retroviral infection

  2008cited by this paper
• Correction: The Malaria Secretome: From Algorithms to Essential Function in Blood Stage Infection

  2008cited by this paper
• Schistosoma mansoni: germ-line transformation approaches and actin-promoter analysis.

  2007cited by this paper
• piggyBac transposon mediated transgenesis of the human blood fluke, Schistosoma mansoni

  2007cited by this paper
• Technology transfer from worms and flies to vertebrates: transposition-based genome manipulations and their future perspectives

  2007cited by this paper
• Genetic manipulation of schistosomes.

  2007cited by this paper
• DNA transposons and the evolution of eukaryotic genomes.

  2007cited by this paper
• Transgenesis of schistosomes: approaches employing mobile genetic elements

  2007cited by this paper
• Manipulating the manipulators: advances in parasitic helminth transgenesis and RNAi.

  2007cited by this paper
• Characterization and Comparison of Chicken U6 Promoters for the Expression of Short Hairpin RNAs

  2007cited by this paper
• PiggyBac transposon-mediated gene transfer in human cells.

  2007cited by this paper
• TGF-β Signaling Controls Embryo Development in the Parasitic Flatworm Schistosoma mansoni

  2007cited by this paper
• Transfection of Schistosoma mansoni by electroporation and the description of a new promoter sequence for transgene expression.

  2007cited by this paper
• Transduction of Schistosoma mansoni by vesicular stomatitis virus glycoprotein-pseudotyped Moloney murine leukemia retrovirus.

  2006cited by this paper
• Redox Balance Mechanisms in Schistosoma mansoni Rely on Peroxiredoxins and Albumin and Implicate Peroxiredoxins as Novel Drug Targets*

  2006cited by this paper
• Long-term suppression of cathepsin B levels by RNA interference retards schistosome growth.

  2005cited by this paper
• Biolistic transformation of Schistosoma mansoni with 5' flanking regions of two peptidase genes promotes tissue-specific expression.

  2005cited by this paper
• Characterisation and application of a bovine U6 promoter for expression of short hairpin RNAs

  2005cited by this paper
• Drosophila U6 promoter-driven short hairpin RNAs effectively induce RNA interference in Schneider 2 cells.

  2005cited by this paper
• High-efficiency transformation of Plasmodium falciparum by the lepidopteran transposable element piggyBac.

  2005cited by this paper
• Schistosoma japonicum: a method for transformation by electroporation.

  2005cited by this paper
• Unlocking the potential of the human genome with RNA interference

  2004cited by this paper
• Transgene expression in Schistosoma mansoni: introduction of RNA into schistosomula by electroporation.

  2004cited by this paper
• The uptake of Texas Red-BSA in the excretory system of schistosomes and its colocalisation with ER60 promoter-induced GFP in transiently transformed adult males.

  2003cited by this paper
• Suppression of cathepsin B expression in Schistosoma mansoni by RNA interference.

  2003cited by this paper
• Transgenic planarian lines obtained by electroporation using transposon-derived vectors and an eye-specific GFP marker

  2003cited by this paper
• Using RNA interference to manipulate endogenous gene expression in Schistosoma mansoni sporocysts.

  2003cited by this paper
• Cloning of 5' and 3' flanking regions of the Schistosoma mansoni calcineurin A gene and their characterization in transiently transformed parasites.

  2003cited by this paper
• Transplantation of in vitro-generated Schistosoma mansoni mother sporocysts into Biomphalaria glabrata

  2003cited by this paper
• Schistosoma mansoni miracidia transformed by particle bombardment infect Biomphalaria glabrata snails and develop into transgenic sporocysts.

  2003cited by this paper
• Characterisation of the cysteine protease ER60 in transgenic Schistosoma mansoni larvae.

  2002cited by this paper
• Identification of Schistosoma mansoni gender-associated gene transcripts by cDNA microarray profiling

  2002cited by this paper
• HSP70-controlled GFP expression in transiently transformed schistosomes.

  2002cited by this paper
• Many Nonmammalian Cells Exhibit Postentry Blocks to Transduction by Gammaretroviruses Pseudotyped with Various Viral Envelopes, Including Vesicular Stomatitis Virus G Glycoprotein

  2001cited by this paper
• Flukes without snails: advances in the in vitro cultivation of intramolluscan stages of trematodes.

  2000cited by this paper
• Transient expression of DNA and RNA in parasitic helminths by using particle bombardment.

  1999cited by this paper
• Resident aliens: the Tc1/mariner superfamily of transposable elements.

  1999cited by this paper
• Precise excision of TTAA‐specific lepidopteran transposons piggyBac (IFP2) and tagalong (TFP3) from the baculovirus genome in cell lines from two species of Lepidoptera

  1996cited by this paper
• Excision of the piggyBac transposable element in vitro is a precise event that is enhanced by the expression of its encoded transposase

  1996cited by this paper
• Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells.

  1993cited by this paper
• Human gene therapy comes of age

  1992cited by this paper
• Replication

  1992cited by this paper
• Pseudotype formation of murine leukemia virus with the G protein of vesicular stomatitis virus

  1991cited by this paper
• Transposon mutagenesis of baculoviruses: analysis of Trichoplusia ni transposon IFP2 insertions within the FP-locus of nuclear polyhedrosis viruses.

  1989influential reference
• Characterization of membrane components of the erythrocyte involved in vesicular stomatitis virus attachment and fusion at acidic pH.

  1987cited by this paper
• Transposon-mediated mutagenesis of a baculovirus.

  1985cited by this paper
• Molecular and biochemical parasitology

  1980cited by this paper
• Growth and differentiation.

  1967cited by this paper
• Growth and differentiation.

  1962cited by this paper

• Targeted insertion and reporter transgene activity at a gene safe harbor of the 1 human blood fluke, Schistosoma mansoni 2

  2023cites this paper
• Harnessing model organism genomics to underpin the machine learning-based prediction of essential genes in eukaryotes - Biotechnological implications.

  2021cites this paper
• Programmed genome editing of the omega-1 ribonuclease of the blood fluke, Schistosoma mansoni

  2019cites this paper
• Developmental Sensitivity in Schistosoma mansoni to Puromycin To Establish Drug Selection of Transgenic Schistosomes

  2018cites this paper
• Functional Genomics Tools for Haemonchus contortus and Lessons From Other Helminths.

  2016cites this paper
• Transfection of Platyhelminthes

  2015cites this paper
• Transient transgenesis of the tapeworm Taenia crassiceps

  2015cites this paper
• New research tools for urogenital schistosomiasis.

  2015cites this paper
• Venus Kinase Receptors: Prospects in Signaling and Biological Functions of These Invertebrate Kinases

  2014cites this paper
• Heterologous expression in Caenorhabditis elegans as an alternative approach to functional studies in Schistosoma mansoni

  2014cites this paper
• Pseudotyped murine leukemia virus for schistosome transgenesis: approaches, methods and perspectives

  2014cites this paper
• New approaches for understanding mechanisms of drug resistance in schistosomes

  2013cites this paper
• Germline Transgenesis and Insertional Mutagenesis in Schistosoma mansoni Mediated by Murine Leukemia Virus

  2012cites this paper
• Developments in RNA interference and genetic transformation to define gene function in parasitic helminths

  2012cites this paper
• An antibiotic selection marker for schistosome transgenesis.

  2012cites this paper