Peroxiredoxin-1 from Schistosoma japonicum functions as a scavenger against hydrogen peroxide but not nitric oxide.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Molecular and biochemical parasitology (Print)

• Publication date

  2009-03-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.molbiopara.2008.11.002PMID 19041905
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2008cited by this paper
• Antioxidant gene expression and function in in vitro-developing Schistosoma mansoni mother sporocysts: possible role in self-protection

  2007cited by this paper
• In vitro and in vivo characterization of alkyl hydroperoxide reductase mutant strains of Helicobacter hepaticus.

  2007cited by this paper
• Optimizing gene suppression in schistosomes using RNA interference.

  2007cited by this paper
• Lipid peroxidation as a source of oxidative damage in Helicobacter pylori: protective roles of peroxiredoxins.

  2006cited by this paper
• 2-Cys peroxiredoxins from Schistosoma japonicum: the expression profile and localization in the life cycle.

  2006cited by this paper
• Redox Balance Mechanisms in Schistosoma mansoni Rely on Peroxiredoxins and Albumin and Implicate Peroxiredoxins as Novel Drug Targets*

  2006cited by this paper
• A mosquito 2-Cys peroxiredoxin protects against nitrosative and oxidative stresses associated with malaria parasite infection.

  2006cited by this paper
• Long-term suppression of cathepsin B levels by RNA interference retards schistosome growth.

  2005cited by this paper
• Intracellular messenger function of hydrogen peroxide and its regulation by peroxiredoxins.

  2005cited by this paper
• Thioredoxin Peroxidase Secreted by Fasciola hepatica Induces the Alternative Activation of Macrophages

  2005cited by this paper
• Peroxiredoxin II functions as a signal terminator for H2O2‐activated phospholipase D1

  2005cited by this paper
• Schistosoma japonicum: localization of calpain in the penetration glands and secretions of cercariae.

  2005cited by this paper
• Functional expression and characterization of Echinococcus granulosus thioredoxin peroxidase suggests a role in protection against oxidative damage.

  2004cited by this paper
• Biochemical Characterization of 2-Cys Peroxiredoxins from Schistosoma mansoni*

  2004influential reference
• Regeneration of Peroxiredoxins by p53-Regulated Sestrins, Homologs of Bacterial AhpD

  2004cited by this paper
• Using RNA interference to manipulate endogenous gene expression in Schistosoma mansoni sporocysts.

  2003cited by this paper
• ATP-dependent reduction of cysteine–sulphinic acid by S. cerevisiae sulphiredoxin

  2003cited by this paper
• Suppression of cathepsin B expression in Schistosoma mansoni by RNA interference.

  2003cited by this paper
• Structure, mechanism and regulation of peroxiredoxins.

  2003cited by this paper
• RNA Interference Identifies Two Hydroperoxide Metabolizing Enzymes That Are Essential to the Bloodstream Form of the African Trypanosome*

  2003cited by this paper
• Disruption of the Plasmodium falciparum 2‐Cys peroxiredoxin gene renders parasites hypersensitive to reactive oxygen and nitrogen species

  2003cited by this paper
• Peroxiredoxin Evolution and the Regulation of Hydrogen Peroxide Signaling

  2003cited by this paper
• Reversing the Inactivation of Peroxiredoxins Caused by Cysteine Sulfinic Acid Formation

  2003cited by this paper
• Inactivation of Human Peroxiredoxin I during Catalysis as the Result of the Oxidation of the Catalytic Site Cysteine to Cysteine-sulfinic Acid*

  2002cited by this paper
• Proteomics Analysis of Cellular Response to Oxidative Stress

  2002cited by this paper
• Schistosome Infection Stimulates Host CD4+ T Helper Cell and B-Cell Responses against a Novel Egg Antigen, Thioredoxin Peroxidase

  2001cited by this paper
• Peroxynitrite reductase activity of bacterial peroxiredoxins

  2000cited by this paper
• MOLECULAR AND ENZYMATIC CHARACTERIZATION OF SCHISTOSOMA MANSONI THIOREDOXIN PEROXIDASE

  2000cited by this paper
• Lipid hydroperoxide generation, turnover, and effector action in biological systems.

  1998cited by this paper
• Nitric oxide produced in the lungs of mice immunized with the radiation‐attenuated schistosome vaccine is not the major agent causing challenge parasite elimination

  1998cited by this paper
• Peroxidoxins: a new antioxidant family.

  1998cited by this paper
• Do antioxidants play a role in schistosome host-parasite interactions?

  1998cited by this paper
• Developmental differences determine larval susceptibility to nitric oxide-mediated killing in a murine model of vaccination against Schistosoma mansoni

  1997cited by this paper
• Molecular cloning, expression and enzymatic activity of a thioredoxin peroxidase from Dirofilaria immitis.

  1997cited by this paper
• Molecular cloning, expression and enzymatic activity of a thioredoxin peroxidase from Dirofilaria immitis

  1997cited by this paper
• Cloning of peroxiredoxin, a novel antioxidant enzyme, from the helminth parasite Fasciola hepatica

  1997cited by this paper
• Cloning and sequencing of thiol-specific antioxidant from mammalian brain: alkyl hydroperoxide reductase and thiol-specific antioxidant define a large family of antioxidant enzymes.

  1994cited by this paper
• Cloning, sequencing, and mutation of thiol-specific antioxidant gene of Saccharomyces cerevisiae.

  1993cited by this paper
• cDNA cloning and functional expression of the Schistosoma mansoni protective antigen triose-phosphate isomerase.

  1992cited by this paper
• Rats, mice and men - models for immune effector mechanisms against schistosomiasis.

  1986cited by this paper
• Cell-mediated damage to helminths.

  1984cited by this paper
• Lipid peroxidation of human erythrocyte ghosts induced by organic hydroperoxides.

  1983cited by this paper
• Role of cell-generated hydrogen peroxide in granulocyte-mediated killing of schistosomula of Schistosoma mansoni in vitro.

  1981cited by this paper

• How to train your myeloid cells: a way forward for helminth vaccines?

  2023cites this paper
• Schistosome Secretomes: Running title: Blood fluke protein secretions.

  2022cites this paper
• Immunomodulatory and biological properties of helminth-derived small molecules: Potential applications in diagnostics and therapeutics

  2022cites this paper
• Molecular characterization and functional analysis of Schistosoma mekongi neuroglobin homolog.

  2022cites this paper
• Calpain inhibitors suppress both extracellular vesicle-mediated secretion of miRNAs and egg production from paired adults of Schistosoma japonicum.

  2022cites this paper
• Immune Evasion Strategies of Schistosomes

  2021cites this paper
• Schistosome immunomodulators

  2021cites this paper
• Proteomic Analysis of Adult Schistosoma mekongi Somatic and Excretory-Secretory Proteins.

  2020cites this paper
• Function of the lesswright (lwr) gene in the growth, development, and reproduction of Schistosoma japonicum.

  2019cites this paper
• RNA interference in vivo in Schistosoma japonicum: Establishing and optimization of RNAi mediated suppression of gene expression by long dsRNA in the intra-mammalian life stages of worms.

  2018cites this paper
• Echinococcus granulosus sensu stricto: silencing of thioredoxin peroxidase impairs the differentiation of protoscoleces into metacestodes

  2018cites this paper
• Chemotherapy Against Schistosomiasis

  2017cites this paper
• Cloning and characterization of thioredoxin peroxidases from Trichinella spiralis.

  2016cites this paper
• Peroxiredoxin 1 inhibits the oxidative stress induced apoptosis in renal tubulointerstitial fibrosis

  2015cites this paper
• Transfection of Platyhelminthes

  2015cites this paper
• Expression and characterization of a phospholipid hydroperoxide glutathione peroxidase gene in Schistosoma japonicum

  2015cites this paper
• Tuning of Peroxiredoxin Catalysis for Various Physiological Roles

  2014cites this paper
• Protective mechanisms of helminths against reactive oxygen species are highly promising drug targets.

  2014cites this paper
• Transcriptional Responses of In Vivo Praziquantel Exposure in Schistosomes Identifies a Functional Role for Calcium Signalling Pathway Member CamKII

  2013cites this paper
• Localization and expression profiling of a 31 kDa antigenic repetitive protein Sjp_0110390 in Schistosoma japonicum life stages.

  2013cites this paper
• In vitro cultivation of Schistosoma japonicum-parasites and cells.

  2013cites this paper
• Challenges in Controlling and Eliminating Schistosomiasis

  2013cites this paper
• Characterization and Expression of the Schistosoma japonicum Thioredoxin Peroxidase-2 Gene

  2013cites this paper
• Proteomics analysis of differentially expressed proteins in schistosomula and adult worms of Schistosoma japonicum.

  2013cites this paper
• Distribution of lethal giant larvae (Lgl) protein in the tegument and negative impact of siRNA-based gene silencing on worm surface structure and egg hatching in Schistosoma japonicum

  2013cites this paper
• Thioredoxin Glutathione Reductase-Dependent Redox Networks in Platyhelminth Parasites

  2013cites this paper
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  2012cites this paper
• Characterization of thioredoxin glutathione reductase in Schiotosoma japonicum.

  2012cites this paper
• The redox biology of schistosome parasites and applications for drug development.

  2012cites this paper
• Peroxiredoxins in Parasites

  2012cites this paper
• Functional genomics approaches in parasitic helminths

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• Helminth infection in populations undergoing epidemiological transition: a friend or foe?

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  2010cites this paper
• Advances in mRNA Silencing and Transgene Expression: a Gateway to Functional Genomics in Schistosomes

  2009cites this paper