S-nitrosohemoglobin: a mechanism for its formation in conjunction with nitrite reduction by deoxyhemoglobin.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Nitric oxide

• Publication date

  2006-08-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/J.NIOX.2006.01.012PMID 16545588
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Hemoglobin-mediated, hypoxia-induced vasodilation via nitric oxide: mechanism(s) and physiologic versus pathophysiologic relevance.

  2005cited by this paper
• The reaction between nitrite and hemoglobin: the role of nitrite in hemoglobin-mediated hypoxic vasodilation.

  2005cited by this paper
• Vasorelaxation by Red Blood Cells and Impairment in Diabetes: Reduced Nitric Oxide and Oxygen Delivery by Glycated Hemoglobin

  2004cited by this paper
• Nitroxides scavenge myeloperoxidase-catalyzed thiyl radicals in model systems and in cells.

  2004cited by this paper
• S-nitrosothiols in the blood: roles, amounts, and methods of analysis.

  2004cited by this paper
• Transduction of NO-bioactivity by the red blood cell in sepsis: novel mechanisms of vasodilation during acute inflammatory disease.

  2004cited by this paper
• Active Nitric Oxide Produced in the Red Cell under Hypoxic Conditions by Deoxyhemoglobin-mediated Nitrite Reduction*

  2003cited by this paper
• Plasma nitrite reflects constitutive nitric oxide synthase activity in mammals.

  2003cited by this paper
• Methodologies for the Sensitive and Specific Measurement of S -nitrosothiols, Iron-nitrosyls, and Nitrite in Biological Samples

  2003cited by this paper
• Reactions of Deoxy-, Oxy-, and Methemoglobin with Nitrogen Monoxide

  2003cited by this paper
• Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation

  2003cited by this paper
• NO adducts in mammalian red blood cells: too much or too little?

  2003cited by this paper
• Routes to S-nitroso-hemoglobin formation with heme redox and preferential reactivity in the β subunits

  2003cited by this paper
• Nitrite catalyzes reductive nitrosylation of the water-soluble Ferri-Heme model FeIII(TPPS) to FeII(TPPS)(NO).

  2003cited by this paper
• S-nitrosylation in health and disease.

  2003cited by this paper
• S-Nitrosohemoglobin Is Unstable in the Reductive Erythrocyte Environment and Lacks O2/NO-linked Allosteric Function*

  2002cited by this paper
• Haemoglobin: NO transporter, NO inactivator or NOne of the above?

  2002cited by this paper
• Nitric oxide is consumed, rather than conserved, by reaction with oxyhemoglobin under physiological conditions

  2002cited by this paper
• Nitric oxide in the human respiratory cycle

  2002cited by this paper
• The biochemistry and physiology of S-nitrosothiols.

  2002cited by this paper
• Concomitant S‐, N‐, and heme‐nitros(yl)ation in biological tissues and fluids: implications for the fate of NO in vivo

  2002cited by this paper
• Release of nitric oxide from S-nitrosohemoglobin. Electron transfer as a response to deoxygenation.

  2001cited by this paper
• Export by red blood cells of nitric oxide bioactivity

  2001cited by this paper
• Nitrite uptake and metabolism and oxidant stress in human erythrocytes.

  2000cited by this paper
• A chemiluminescense-based assay for S-nitrosoalbumin and other plasma S-nitrosothiols

  2000cited by this paper
• Electron tunneling pathways in proteins.

  2000cited by this paper
• New chemical and biological aspects of S-nitrosothiols.

  2000cited by this paper
• Ellipsoidal Delocalization of Tunneling Electrons in Long-Range Electron Transfer Proteins

  1999cited by this paper
• Natural engineering principles of electron tunnelling in biological oxidation–reduction

  1999cited by this paper
• An Electron Spin Resonance Spin-trapping Investigation of the Free Radicals Formed by the Reaction of Mitochondrial Cytochromec Oxidase with H2O2 *

  1999cited by this paper
• Relationships between nitric oxide, nitroxyl ion, nitrosonium cation and peroxynitrite.

  1999cited by this paper
• Nitric oxide as a signaling molecule in the vascular system: an overview.

  1999cited by this paper
• Concerted nitric oxide/oxygen delivery by hemoglobin.

  1999cited by this paper
• The oxyhemoglobin reaction of nitric oxide.

  1999cited by this paper
• Superoxide Produced in the Heme Pocket of the β-Chain of Hemoglobin Reacts with the β-93 Cysteine To Produce a Thiyl Radical†

  1998cited by this paper
• Superoxide produced in the heme pocket of the beta-chain of hemoglobin reacts with the beta-93 cysteine to produce a thiyl radical.

  1998cited by this paper
• Reductive assays for S-nitrosothiols: implications for measurements in biological systems.

  1998cited by this paper
• A tutorial on the diffusibility and reactivity of free nitric oxide.

  1997cited by this paper
• Blood flow regulation by S-nitrosohemoglobin in the physiological oxygen gradient.

  1997cited by this paper
• Characterisation of S‐nitrosohaemoglobin by mass spectrometry

  1997cited by this paper
• S-nitrosohemoglobin in the fetal circulation may represent a cycle for blood pressure regulation.

  1997cited by this paper
• S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control

  1996cited by this paper
• Studies on the Reaction Mechanism for Reductive Nitrosylation of Ferrihemoproteins in Buffer Solutions

  1996cited by this paper
• Decomposition of S-nitrosoglutathione in the presence of copper ions and glutathione.

  1996cited by this paper
• Mechanism of Nitric Oxide Release from S-Nitrosothiols*

  1996cited by this paper
• Identification of Cu+ as the effective reagent in nitric oxide formation from S-nitrosothiols (RSNO)

  1996cited by this paper
• Methods in nitric oxide research

  1996cited by this paper
• Kinetics of Nitrosation of Thiols by Nitric Oxide in the Presence of Oxygen (*)

  1995cited by this paper
• Reaction kinetics for nitrosation of cysteine and glutathione in aerobic nitric oxide solutions at neutral pH. Insights into the fate and physiological effects of intermediates generated in the NO/O2 reaction.

  1994cited by this paper
• Biological activity of S-nitrosothiols: the role of nitric oxide.

  1993cited by this paper
• Electron-tunneling pathways in proteins.

  1992cited by this paper
• Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin.

  1992cited by this paper
• Redox reactivity of iron(III) porphyrins and heme proteins with nitric oxide. Nitrosyl transfer to carbon, oxygen, nitrogen, and sulfur.

  1990cited by this paper
• Spin trapping the cysteine thiyl radical with phenyl-N-t-butylnitrone.

  1988cited by this paper
• Reaction of nitric oxide with heme proteins and model compounds of hemoglobin.

  1987cited by this paper
• Nitrosyliron(III) hemoglobin: autoreduction and spectroscopy.

  1986cited by this paper
• [22] Spin trapping

  1984cited by this paper
• Spin trapping.

  1984cited by this paper
• Spin trapping. Kinetics of the reaction of superoxide and hydroxyl radicals with nitrones

  1980cited by this paper
• Changes in the 4-PDS-reactive -SH groups of hemoglobin associated with the binding of phosphates and ligands.

  1969cited by this paper
• Structure and function of haemoglobin: IV. A three-dimensional Fourier synthesis of horse deoxyhaemoglobin at 5.5 Å resolution

  1967cited by this paper
• Structure and function of haemoglobin. 3. A three-dimensional fourier synthesis of human deoxyhaemoglobin at 5.5 Angstrom resolution.

  1967cited by this paper

• Electrokinetics of nitrite to ammonia conversion in the neutral medium over a platinum surface.

  2024cites this paper
• Erythrocyte metabolism

  2024cites this paper
• Nitric Oxide Synthases in Cyanobacteria: Diversity, Cellular Implications and Ecological Pertinence

  2024cites this paper
• NO news: S-(de)nitrosylation of cathepsins and their relationship with cancer.

  2022cites this paper
• Mechanisms of Physiological and Neurotoxic Action of Hyperbaric Oxygen

  2022cites this paper
• The enzymatic function of the honorary enzyme: S-nitrosylation of hemoglobin in physiology and medicine.

  2021cites this paper
• The Noncanonical Pathway for In Vivo Nitric Oxide Generation: The Nitrate-Nitrite-Nitric Oxide Pathway

  2020cites this paper
• The dichotomous role of H2S in cancer cell biology? Déjà vu all over again.

  2018cites this paper
• Erythrocytes and Vascular Function: Oxygen and Nitric Oxide

  2018cites this paper
• S-Nitrosothiols and Nitric Oxide Biology

  2017cites this paper
• Structure and function of haemoglobins.

  2017cites this paper
• Thiolate-based dinitrosyl iron complexes: Decomposition and detection and differentiation from S-nitrosothiols.

  2017cites this paper
• Recent insights into nitrite signaling processes in blood

  2017cites this paper
• Ferriheme catalyzes nitric oxide reaction with glutathione to form S-nitrosoglutathione: A novel mechanism for formation of S-nitrosothiols.

  2016cites this paper
• Evaluating the Capacity to Generate and Preserve Nitric Oxide Bioactivity in Highly Purified Earthworm Erythrocruorin

  2014cites this paper
• Mechanisms of nitrite bioactivation.

  2014cites this paper
• Mechanisms of Human Erythrocytic Bioactivation of Nitrite*

  2014cites this paper
• Nitrite binding to globins: linkage isomerism, EPR silence and reductive chemistry

  2014cites this paper
• How biology handles nitrite.

  2014cites this paper
• Detection of S-nitrosothiols.

  2014cites this paper
• Thiol redox biochemistry: insights from computer simulations

  2014cites this paper
• Generating S-Nitrosothiols from Hemoglobin

  2013cites this paper
• Hemoglobin-mediated nitric oxide signaling.

  2013cites this paper
• Role of tomato S-Nitrosoglutathione Reductase (GSNOR) in plant development and disease resistance

  2013cites this paper
• HBOC Vasoactivity: Interplay Between Nitric Oxide Scavenging and Capacity to Generate Bioactive Nitric Oxide Species

  2013cites this paper
• Routes for Formation of S-Nitrosothiols in Blood

  2013cites this paper
• Cytochrome c-mediated formation of S-nitrosothiol in cells.

  2012cites this paper
• Nitrite and Nitrite Reductases: From Molecular Mechanisms to Significance in Human Health and Disease

  2012cites this paper
• Inhaled NO therapy increases blood nitrite, nitrate and S- nitrosohemoglobin concentrations in infants with pulmonary hypertension

  2012cites this paper
• Is Endothelial Nitric Oxide Synthase a Moonlighting Protein Whose Day Job is Cholesterol Sulfate Synthesis? Implications for Cholesterol Transport, Diabetes and Cardiovascular Disease

  2012cites this paper
• Low NO Concentration Dependence of Reductive Nitrosylation Reaction of Hemoglobin*

  2012cites this paper
• Inhaled nitric oxide therapy increases blood nitrite, nitrate, and s-nitrosohemoglobin concentrations in infants with pulmonary hypertension.

  2012cites this paper
• Nitric oxide transport in blood: a third gas in the respiratory cycle.

  2011influential citation
• The quaternary hemoglobin conformation regulates the formation of the nitrite-induced bioactive intermediate and the dissociation of nitric oxide from this intermediate.

  2011cites this paper
• Current perspectives and challenges in understanding the role of nitrite as an integral player in nitric oxide biology and therapy.

  2011cites this paper
• Hemoglobin as a nitrite anhydrase: modeling methemoglobin-mediated N2O3 formation.

  2011cites this paper
• The potential role of the red blood cell in nitrite-dependent regulation of blood flow.

  2011cites this paper
• Structural and Functional Studies Indicating Altered Redox Properties of Hemoglobin E

  2011cites this paper
• Membrane transfer of S-nitrosothiols.

  2011cites this paper
• Determination of s-nitrosothiols in biological fluids by chemiluminescence.

  2011cites this paper
• Parallel evolution of nitric oxide signaling: diversity of synthesis and memory pathways.

  2011cites this paper
• A new paramagnetic intermediate formed during the reaction of nitrite with deoxyhemoglobin.

  2011cites this paper
• Glass matrix-facilitated thermal reduction: a tool for probing reactions of met hemoglobin with nitrite and nitric oxide.

  2010cites this paper
• A reagentless nitric oxide biosensor based on the direct electrochemistry of hemoglobin adsorbed on the gold colloids modified carbon paste electrode

  2010cites this paper
• Erythrocyte-dependent regulation of human skeletal muscle blood flow: role of varied oxyhemoglobin and exercise on nitrite, S-nitrosohemoglobin, and ATP.

  2010cites this paper
• Measurement of plasma nitrite by chemiluminescence.

  2010cites this paper
• Reaction between nitric oxide, glutathione, and oxygen in the presence and absence of protein: How are S-nitrosothiols formed?

  2010cites this paper
• Cardioprotective actions of nitrite therapy and dietary considerations.

  2009cites this paper
• Quantification of Intermediates Formed during the Reduction of Nitrite by Deoxyhemoglobin*

  2009cites this paper
• Nitrite-induced improved blood circulation associated with an increase in a pool of RBC-NO with no bioactivity.

  2009cites this paper
• Activation and inhibition of soluble guanylyl cyclase by S-nitrosocysteine: involvement of amino acid transport system L.

  2009cites this paper
• Nitrite enhances RBC hypoxic ATP synthesis and the release of ATP into the vasculature: a new mechanism for nitrite-induced vasodilation.

  2009cites this paper
• Regulation of nitrite transport in red blood cells by hemoglobin oxygen fractional saturation.

  2009cites this paper
• The new chemical biology of nitrite reactions with hemoglobin: R-state catalysis, oxidative denitrosylation, and nitrite reductase/anhydrase.

  2009cites this paper
• Kinetics of reaction of nitrite with deoxy hemoglobin after rapid deoxygenation or predeoxygenation by dithionite measured in solution and bound to the cytoplasmic domain of band 3 (SLC4A1).

  2008cites this paper
• Hypoxic Vasodilation by Red Blood Cells: Evidence for an S-Nitrosothiol–Based Signal

  2008cites this paper
• Transnitrosation signals oxyhemoglobin desaturation.

  2008cites this paper
• Diversity of Globin Function: Enzymatic, Transport, Storage, and Sensing*

  2008cites this paper
• Nitric oxide-mediated signaling in pulmonary endothelial cells

  2008cites this paper
• Chemiluminescent detection of S-nitrosated proteins: comparison of tri-iodide, copper/CO/cysteine, and modified copper/cysteine methods.

  2008cites this paper
• S-nitrosothiol assays that avoid the use of iodine.

  2008influential citation
• Nitrite reductase activity of hemoglobin as a systemic nitric oxide generator mechanism to detoxify plasma hemoglobin produced during hemolysis.

  2008cites this paper
• The hemoglobin-nitric oxide axis: implications for transfusion therapeutics

  2007cites this paper
• The role of blood nitrite in the control of hypoxic vasodilation

  2007cites this paper
• S-nitrosohemoglobin deficiency: A mechanism for loss of physiological activity in banked blood

  2007cites this paper
• Intermediates detected by visible spectroscopy during the reaction of nitrite with deoxyhemoglobin: the effect of nitrite concentration and diphosphoglycerate.

  2007cites this paper
• NO metabolite flux across the human coronary circulation.

  2007cites this paper
• Nitrite infusion increases cerebral blood flow and decreases mean arterial blood pressure in rats: a role for red cell NO.

  2007cites this paper
• Catalytic generation of N2O3 by the concerted nitrite reductase and anhydrase activity of hemoglobin.

  2007cites this paper
• Red blood cells prevent inhibition of hypoxic pulmonary vasoconstriction by nitrite in isolated, perfused rat lungs.

  2007cites this paper
• Detection of S-nitrosothiols in biological fluids: a comparison among the most widely applied methodologies.

  2007cites this paper
• Proteomic methods for analysis of S-nitrosation.

  2007cites this paper
• Nitric Oxide Regulation of Microvascular Oxygen

  2007cites this paper
• Hemoglobin S-nitrosation on oxygenation of nitrite/deoxyhemoglobin incubations is attenuated by methemoglobin.

  2007cites this paper
• S-nitrosylation and PEGylation of hemoglobin: toward a blood substitute that recapitulates blood.

  2007cites this paper
• Transport and peripheral bioactivities of nitrogen oxides carried by red blood cell hemoglobin: role in oxygen delivery.

  2007cites this paper
• Deoxymyoglobin Is a Nitrite Reductase That Generates Nitric Oxide and Regulates Mitochondrial Respiration

  2007cites this paper
• Measurement of plasma nitrite by chemiluminescence without interference of S-, N-nitroso and nitrated species.

  2007cites this paper
• Nitrite as a vascular endocrine nitric oxide reservoir that contributes to hypoxic signaling, cytoprotection, and vasodilation.

  2006cites this paper
• Allylic nitro compounds as nitrite donors.

  2006cites this paper
• Nitrite in nitric oxide biology: cause or consequence? A systems-based review.

  2006cites this paper
• An S-nitrosothiol (SNO) synthase function of hemoglobin that utilizes nitrite as a substrate.

  2006cites this paper
• Detecting physiologic fluctuations in the S-nitrosohemoglobin micropopulation: Triiodide versus 3C.

  2006cites this paper