Adenosine inhibits the accumulation of cyclic AMP in cultured brain cells

No abstract is available for this paper.

• Publication year

  1978

• Venue

  Nature

• Publication date

  1978-12-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1038/276839a0PMID 214714
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• ADRENERGIC α‐ AND β‐RECEPTORS EXPRESSED BY THE SAME CELL TYPE IN PRIMARY CULTURE OF PERINATAL MOUSE BRAIN

  1978cited by this paper
• Adrenergic alpha- and beta-receptors expressed by the same cell type in primary culture of perinatal mouse brain.

  1978cited by this paper
• Glia maturation factor: effect on chemical differentiation of glioblasts in culture.

  1977cited by this paper
• Elevation of cyclic AMP in C-1300 murine neuroblastoma by adenosine and related compounds and the antagonism of this response by methylxanthines.

  1977cited by this paper
• Glial fibrillary acidic protein in primary astroglial cell cultures derived from newborn rat brain

  1977cited by this paper
• Two distinct adenosine-sensitive sites on adenylate cyclase.

  1977cited by this paper
• NEUROBLASTOMA CELL ADENYLATE CYCLASE: DIRECT ACTIVATION BY ADENOSINE AND PROSTAGLANDINS 1

  1976cited by this paper
• Regulation of adenylate cyclase from cultured human cell lines by adenosine.

  1976cited by this paper
• Enkephalin regulates the levels of cyclic nucleotides in neuroblastoma × glioma hybrid cells

  1976cited by this paper
• Taurine uptake in astrocytes cultured from dissociated mouse brain hemispheres.

  1976cited by this paper
• Effects of adenosine deaminase on cyclic adenosine monophosphate accumulation, lipolysis, and glucose metabolism of fat cells.

  1975cited by this paper
• Formation of adenosine 3',5'-monophosphate from adenosine in mouse thymocytes.

  1975cited by this paper
• Effects of adenosine on levels of adenosine cyclic 3',5'-monophosphate in human blood platelets in relation to adenosine incorporation and platelet aggregation.

  1975cited by this paper
• Adenosine-elicited accumulation of cyclic AMP in brain slices: potentiation by agents which inhibit uptake of adenosine.

  1974cited by this paper
• Regulation of adenosine 3':5'-monophosphate content in human astrocytoma cells by adenosine and the adenine nucleotides.

  1974cited by this paper
• Regulation of glycerol phosphate dehydrogenase by hydrocortisone in dissociated rat cerebral cell cultures.

  1974cited by this paper
• Maturation-stimulating effect of brain extract and dibutyryl cyclic AMP on dissociated embryonic brain cells in culture.

  1973cited by this paper
• Maturation-stimulation effect of brain extract and dibutyryl cyclic AMP on dissociated embryonic brain cells in culture.

  1973cited by this paper
• Inhibition of adenosine cyclic 3', 5'-monophosphate accumulation in fat cells by adenosine, N6-(phenylisopropyl) adenosine, and related compounds.

  1973cited by this paper
• Adenosine-mediated elevation of cyclic 3':5'-adenosine monophosphate concentrations in cultured mouse neuroblastoma cells.

  1973cited by this paper
• Adenosine cyclic 3',5'-monophosphate in fetal rat brain cell cultures. I. Effect of catecholamines.

  1972cited by this paper
• Effects of adenosine nucleosides on adenylate cyclase, phosphodiesterase, cyclic adenosine monophosphate accumulation, and lipolysis in fat cells.

  1972cited by this paper
• Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures.

  1972cited by this paper
• Analogues of 4-(3,4-dimethoxybenzyl)-2-imidazolidinone as potent inhibitors of rat erythrocyte adenosine cyclic 3',5'-phosphate phosphodiesterase.

  1971cited by this paper
• The effect of adenosine and adenine nucleotides on the cyclic adenosine 3', 5'-phosphate content of guinea pig cerebral cortex slices.

  1970cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

• C3 amino-substituted chalcone derivative with selective adenosine rA1 receptor affinity in the micromolar range

  2020influential citation
• The Way to a Human’s Brain Goes Through Their Stomach: Dietary Factors in Major Depressive Disorder

  2020cites this paper
• 2 Early History of Purinergic Signalling

  2020cites this paper
• The role of adenosine receptors in mood and anxiety disorders

  2019cites this paper
• The Adenosine Receptor: A Homeostatic Neuromodulator for Fine-Tuning Control of Cognition

  2018cites this paper
• 31 Ethanol Interference on Adenosine System

  2018cites this paper
• Adenosine receptor agonists differentially affect the anticonvulsant action of carbamazepine and valproate against maximal electroshock test-induced seizures in mice

  2017cites this paper
• Neladenoson Bialanate Hydrochloride: A Prodrug of a Partial Adenosine A1 Receptor Agonist for the Chronic Treatment of Heart Diseases

  2017cites this paper
• Purine nucleosides in neuroregeneration and neuroprotection.

  2016cites this paper
• Metabolic modifications associated with memory deficits

  2016cites this paper
• VI. Nomenclature and Classification of Purinoceptors *

  2016cites this paper
• The Origins of Spontaneous Morphological Activity in Kölliker’s Organ of the Developing Rat Cochlea

  2015cites this paper
• Effects of Adenosine Receptors

  2015cites this paper
• A1 adenosine receptor-mediated GIRK channels contribute to the resting conductance of CA1 neurons in the dorsal hippocampus.

  2015cites this paper
• Autonomic Neuroscience: Basic and Clinical

  2015cites this paper
• Alpha2-adrenoceptor and adenosine A1 receptor within the nucleus tractus solitarii in hypertension development.

  2015cites this paper
• Adenosine receptor control of cognition in normal and disease.

  2014cites this paper
• Chapter 4 Molecular modeling and docking studies of PDE2 inhibitors

  2014cites this paper
• A INOSINA PREVINE ALTERAÇÕES COMPORTAMENTAIS E BIOQUÍMICAS INDUZIDAS PELO METILMERCÚRIO EM CAMUNDONGOS

  2014cites this paper
• Combined 2D and 3D-QSAR, molecular modelling and docking studies of pyrazolodiazepinones as novel phosphodiesterase 2 inhibitors

  2014cites this paper
• The regulation of ATP release from the urothelium by adenosine and transepithelial potential.

  2013cites this paper
• Wirkungen einer chronischen Vorbehandlung mit dem selektiven Adenosin-A1-Rezeptor- Agonisten 2-Chloro-N6-Cyclopentyladenosin (CCPA) auf die Nierenfunktion der Ratte

  2012cites this paper
• Partial adenosine A1 receptor agonists for cardiovascular therapies

  2012cites this paper
• Investigating the glial contribution to persistent neuropathic pain

  2012cites this paper
• Early History of Purinergic Signalling

  2012cites this paper
• Ethanol Interference on Adenosine System

  2012cites this paper
• Neuroadaptations in adenosine receptor signaling following long-term ethanol exposure and withdrawal.

  2012influential citation
• Characterization of the Solubilized A 1 Adenosine Receptor from Rat Brain Membranes

  2011cites this paper
• Quantitative structure activity relationship (QSAR) of N6-substituted adenosine receptor agonists as potential antihypertensive agents

  2011cites this paper
• Regulación de la plasticidad astrocitaria por ibuprofeno y FGF2

  2011cites this paper
• The birth and postnatal development of purinergic signalling

  2010cites this paper
• Challenging the dogma: Reevaluating the role of astrocyte calcium signaling in physiology.

  2010cites this paper
• Adenosine analogues stimulate cyclic AMP-accumulation in cultured neuroblastoma and glioma cells.

  2009cites this paper
• The role of adenosine A(1) receptors in mediating the inhibitory effects of low frequency stimulation of perforant path on kindling acquisition in rats.

  2009cites this paper
• The adenosine A1 receptor and its ligands.

  2009cites this paper
• Adenosine modulates alpha2-adrenergic receptors through a phospholipase C pathway in brainstem cell culture of rats.

  2009cites this paper
• Transporte de cálcio em células isoladas de hepatopâncreas do caranguejo dulcícola Dilocarcinus pagei: efeito do ATP e Ca2+

  2009cites this paper
• Purinergic receptors in gastrointestinal inflammation.

  2008cites this paper
• Presynaptic adenosine and P2Y receptors.

  2008cites this paper
• Sex differences in the neurotoxic effects of adenosine A1 receptor antagonism during ethanol withdrawal: reversal with an A1 receptor agonist or an NMDA receptor antagonist.

  2008cites this paper
• Effects of adenosine receptor agonists and antagonists on cytochrome P450 extinction in the liver of rats in the course of acute pancreatitis.

  2007cites this paper
• Treatment strategies of age-related memory dysfunction by modulation of neuronal plasticity.

  2007cites this paper
• Role of Adenosine Receptors in the Treatment of Asthma and Chronic Obstructive Pulmonary Disease

  2007cites this paper
• Adenosine modulates transmission at the hippocampal mossy fibre synapse via direct inhibition of presynaptic calcium channels

  2007cites this paper
• Adenosine in the airways: implications and applications.

  2006cites this paper
• The Role of Glial Adenosine Receptors in Neural Resilience and the Neurobiology of Mood Disorders

  2005cites this paper
• Adenosine during prolonged wakefulness in the rat brain

  2005cites this paper
• Design, Synthesis and binding studies of Trisubstitutedpyrazolo(3,4-d)pyrimidines

  2005cites this paper
• Differential Effects of cGMP Produced by Soluble and Particulate Guanylyl Cyclase on Mouse Ventricular Myocytes

  2005cites this paper
• Animal models for the study of adenosine receptor function

  2005cites this paper
• IL-6 expression induced by adenosine A2b receptor stimulation in U373 MG cells depends on p38 mitogen activated kinase and protein kinase C.

  2005cites this paper
• 3 H ]-8-Cyclopentyl-1 , 3-dipropylxanthine Binding to Ax Adenosine Receptors of Intact Rat Ventricular Myocytes

  2005cites this paper
• Universidade Federal do Rio Grande do Sul Instituto de Ciências Básicas da Saúde Curso de Pós-Graduação em Ciências Biológicas: Bioquímica Intervenções no sistema adenosinérgico: avaliação de aspectos neuroquímicos, locomotores e nociceptivos

  2005cites this paper
• Proceedings of the British Pharmacological Society

  2004cites this paper
• Xanthines alter behavior maintained by intracranial electrical stimulation and an operant schedule

  2004cites this paper
• Stereoselective behavioral effects of N6-phenylisopropyl-adenosine and antagonism by caffeine

  2004cites this paper
• Adenosine-induced neuroprotection: involvement of glia cells and cytokines

  2004cites this paper
• Involvement of adenosine receptor activities in aggressive responses produced by clonidine in mice

  2004cites this paper
• Separation of solubilized A2 adenosine receptors of human platelets from non-receptor [3H]NECA binding sites by gel filtration

  2004cites this paper
• Extracellular ATP induces stellation and increases glial fibrillary acidic protein content and DNA synthesis in primary astrocyte cultures

  2004cites this paper
• Localización subcelular y regulación post-traduccional del transportador hepático de adenosina rCNT2

  2004cites this paper
• Adenosine and its receptors : translational studies in asthma and COPD

  2003cites this paper
• Immunorégulation par le NAD extracellulaire : activation via les ADP-ribosyl transférases du récepteur cytolytique P2X7

  2003cites this paper
• Signalling from adenosine receptors to mitogen-activated protein kinases.

  2003cites this paper
• Pyrazolo-triazolo-pyrimidine derivatives as adenosine receptor antagonists: a possible template for adenosine receptor subtypes?

  2002cites this paper
• Adenosine receptor signaling and the activation of mitogen-activated protein kinases

  2002cites this paper
• Molecular Mechanisms of Action of Mood Stabilizers in Bipolar Disorder

  2002cites this paper
• Einfluss von Adenosinrezeptoren auf den peristaltischen Reflex

  2002cites this paper
• Alpha-2 Adrenergic Receptors and Signal Transduction: Effector Output in Relation to G-Protein Coupling and Signalling Cross-Talk

  2002cites this paper
• Role of adenosine and P2 receptors in the penile tumescence in anesthetized dogs.

  2001cites this paper
• Adenosine signaling in outer medullary descending vasa recta.

  2001cites this paper
• Anti-adrenergic effect of adenosine on Na(+)-Ca(2+) exchange current recorded from guinea-pig ventricular myocytes.

  2001cites this paper
• Interleukin-6 Enhances Expression of Adenosine A1 Receptor mRNA and Signaling in Cultured Rat Cortical Astrocytes and Brain Slices

  2001cites this paper
• International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors.

  2001cites this paper
• Therapy of bronchial asthma with adenosine receptor agonists or antagonists.

  2001cites this paper
• In vivo effects of adenosine A2 receptor agonist and antagonist on neuronal and astrocytic intermediary metabolism studied with ex vivo13C MR spectroscopy

  2001cites this paper
• Adenosine receptors and their ligands

  2000cites this paper
• A1 adenosine receptor in human spermatozoa: its role in the fertilization process.

  2000cites this paper
• Agonist-stimulated [35S]GTPγS binding in brain: Modulation by endogenous adenosine

  2000cites this paper
• The role of adenosine A1 receptors in the ATP-evoked Ca2+ response in rat thyroid FRTL-5 cells

  2000cites this paper
• Extracellular ATP as a Regulator of Intracellular Signaling in Thyroid FRTL-5 Cells

  2000cites this paper
• The role of adenosine A(1) receptors in the ATP-evoked Ca(2+) response in rat thyroid FRTL-5 cells.

  2000cites this paper
• In Vivo Effects of Adenosine A1 Receptor Agonist and Antagonist on Neuronal and Astrocytic Intermediary Metabolism Studied with Ex Vivo 13C NMR Spectroscopy

  2000cites this paper
• Masking of forskolin-induced long-term potentiation by adenosine accumulation in area CA1 of the rat hippocampus.

  1999cites this paper
• Carbamazepine-Induced Upregulation of Adenosine A1-Receptors in Astrocyte Cultures Affects Coupling to the Phosphoinositol Signaling Pathway

  1999cites this paper
• Inhibition by adenosine receptor agonists of synaptic transmission in rat periaqueductal grey neurons

  1999cites this paper
• Adenosine-induced renal vasodilatation is prolonged in renal artery stenosis.

  1998cites this paper
• Stress-dependent antinociceptive effects of carbamazepine: a study in stressed and nonstressed rats.

  1998cites this paper
• Adenosine and the nervous system: pharmacological data and therapeutic perspectives.

  1998cites this paper
• Selectivity of action of 8‐alkylamino analogues of N6‐cyclopentyladenosine in vivo: haemodynamic versus anti‐lipolytic responses in rats

  1998cites this paper
• Receptors for purines and pyrimidines.

  1998cites this paper
• History of Extracellular Nucleotides and Their Receptors

  1998cites this paper
• Adenosine A1 receptor promotion of multinucleated giant cell formation by human monocytes: a mechanism for methotrexate-induced nodulosis in rheumatoid arthritis.

  1997cites this paper
• De novo analysis of receptor binding affinity data of 8-ethenyl-xanthine antagonists to adenosine A1 and A2a receptors.

  1997cites this paper
• The striatal adenosinergic modulation of ethanol-induced motor incoordination in rats: possible role of chloride flux.

  1997cites this paper
• Functional and clinical aspects of the myelomonocyte protein calprotectin.

  1997cites this paper
• Adenosine A1 Receptor-Mediated Activation of Phospholipase C in Cultured Astrocytes Depends on the Level of Receptor Expression

  1997cites this paper
• Adenosine A1 receptor promotion of multinucleated giant cell formation by human monocytes. A mechanism for methotrexate‐induced nodulosis in rheumatoid arthritis

  1997cites this paper
• Adenosine and the nervous system: clinical implications.

  1996cites this paper
• Binding thermodynamics at A1 and A2A adenosine receptors.

  1996cites this paper