Primary amebic meningoencephalitis and the biology of Naegleria fowleri.

No abstract is available for this paper.

• Publication year

  1982

• Venue

  Annual Review of Microbiology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1146/ANNUREV.MI.36.100182.000533PMID 6756287
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Granulomatous encephalitis, intracranial arteritis, and mycotic aneurysm due to a free-living ameba

  2004cited by this paper
• Granulomatous Amebic Encephalitis presenting as a cerebral mass lesion

  2004cited by this paper
• Serum agglutination and immunoglobulin levels of mice infected with Naegleria fowleri.

  1982cited by this paper
• Different virulence of Naegleria fowleri strains isolated from a swimming pool.

  1981cited by this paper
• Isolation of Naegleria fowleri from the cooling pond of an electric power plant in France.

  1981cited by this paper
• Virulent Naegleria sp. isolated from a river in Cadiz (Spain).

  1981cited by this paper
• Ultrastructure of Naegleria fowleri enflagellation

  1981cited by this paper
• Primary amoebic meningoencephalitis: a report of two cases and antibiotic and immunologic studies.

  1981cited by this paper
• Immunity to pathogenic free-living amoebae: role of cell-mediated immunity

  1980cited by this paper
• Acridine Orange: Method for Diagnosis of Amoebic Meningitis?

  1980cited by this paper
• Experimental infection of sheep with Naegleria fowleri of human origin.

  1980cited by this paper
• Growth of Naegleria fowleri in several axenic media.

  1980cited by this paper
• Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae.

  1980cited by this paper
• [Examinations on the occurrence of free-living amoebae with possible pathogenic traits in swimming pools (author's transl)].

  1980cited by this paper
• Immunity to pathogenic free-living amoebae: role of humoral antibody

  1980cited by this paper
• Activation of the alternative complement pathway by Naegleria fowleri

  1980cited by this paper
• A case of primary amebic meningoencephalitis in a Nigerian farmer.

  1980cited by this paper
• Naegleria fowleri: trimethoprim sensitivity.

  1980cited by this paper
• Naegleria lovaniensis new species: isolation and identification of six thermophilic strains of a new species found in association with Naegleria fowleri.

  1980cited by this paper
• Activation of complement by Naegleria.

  1980cited by this paper
• Survival of Naegleria fowleri cysts at 4 degrees C for eight months with retention of virulence.

  1980cited by this paper
• Primary amoebic meningo-encephalitis in an indoor heat-exchange swimming pool.

  1979cited by this paper
• Primary amebic meningoencephalitis.

  1979cited by this paper
• Pathogenic free-living amoebae in swimming pools: survey in Belgium.

  1979cited by this paper
• Inhibition by amoeba-specific antiserum and by cytochalasin B of the cytopathogenicity of Naegleria fowleri in mouse embryo-cell cultures.

  1979cited by this paper
• Recovery of soil Amebas from the nasal passages of children during the dusty harmattan period in Zaria.

  1979cited by this paper
• Observations by immunofluorescence microscopy and electron microscopy on the cytopathogenicity of Naegleria fowleri in mouse embryo-cell cultures.

  1979cited by this paper
• Immunization with culture supernatant in experimental amoebic meningoencephalitis.

  1979cited by this paper
• Antibody induced capping and endocytosis of surface antigens in Naegleria fowleri.

  1979cited by this paper
• Susceptibility of Naegleria fowleri to delta 9-tetrahydrocannabinol

  1979cited by this paper
• Prevalence of pathogenic free-living amoebae in Zaria, Nigeria.

  1979cited by this paper
• Cell and mitochondria respiration of Naegleria fowleri.

  1979cited by this paper
• Delayed treatment of experimental amoebic meningo-encephalitis with amphotericin B and tetracycline.

  1979cited by this paper
• Cultivation of pathogenic and nonpathogenic free-living amebae.

  1979cited by this paper
• Naegleria fowleri in chick embryos. Effects of embryo age and incubation temperature, and the infectivity of embryo-derived amebae for mice.

  1979cited by this paper
• Treatment of experimental Naegleria meningoencephalitis with a combination of amphotericin B and rifamycin.

  1979cited by this paper
• Pathogenesis of pathogenic Naegleria amoeba.

  1979cited by this paper
• Protective immunity to Naegleria fowleri in experimental amebic meningoencephalitis.

  1978cited by this paper
• Meningoencephalitis and brain abscess due to a free-living amoeba.

  1978cited by this paper
• Resistance of mice to Naegleria meningoencephalitis transferred by immune serum.

  1978cited by this paper
• [Amoebae in swimming-pools: microbiological and epidemiological aspects (author's transl)].

  1978cited by this paper
• Macromolecular composition and nuclear number during growth of Naegleria fowleri.

  1978cited by this paper
• Virulent Naegleria fowleri in indoor swimming pool.

  1978cited by this paper
• Resistance of pathogenic Naegleria to some common physical and chemical agents

  1978cited by this paper
• The occurrence of amphizoic Amebae in domestic animals.

  1978cited by this paper
• "Commercially available, edible snails Otala lactea (Müller) and Helix aperta (Born) as laboratory hosts of Angiostrongylus cantonensis".

  1978cited by this paper
• Primary amoebic meningoencephalitis

  1978cited by this paper
• Innate resistance of mice to experimental infection with Naegleria fowleri

  1978cited by this paper
• Virulence of pathogenic free-living amebae.

  1978cited by this paper
• Agitated mass cultivation of Naegleria fowleri.

  1977cited by this paper
• Isolation and identification of pathogenic Naegleria from Florida lakes

  1977cited by this paper
• The distribution of Naegleria fowleri in man-made thermal waters.

  1977cited by this paper
• Immunization of mice against Naegleria fowleri infection

  1977cited by this paper
• Amebiasis in Goldfish

  1977cited by this paper
• Isolation and experimental infection of free-living amebae in freshwater fishes.

  1977cited by this paper
• Isolation of the etiological agent of primary amoebic meningoencephalitis from artifically heated waters

  1977cited by this paper
• Changes in the virulence of Naegleria fowleri maintained in vitro.

  1977cited by this paper
• A radioimmunoassay for human antibody specific for microbial antigens.

  1977cited by this paper
• Limax Amoebae in Public Swimming Pools of Albany, Schenectady, and Rensselaer Counties, New York: Their Concentration, Correlations, and Significance

  1977cited by this paper
• Concanavalin A-induced agglutination of Naegleria.

  1977cited by this paper
• The nature of a cytopathogenic material present in amebae of the genus Naegleria.

  1977cited by this paper
• Antifungal agents: recent developments.

  1977cited by this paper
• Analyses of Pathogenic and nonpathogenic Acanthamoeba and Naegleria for lectin-induced agglutination.

  1977cited by this paper
• Cell size, macromolecular composition, and O2 consumption during agitated cultivation of Naegleria gruberi.

  1977cited by this paper
• Cell differentiation in Naegleria gruberi.

  1977cited by this paper
• Amoebic meningoencephalitis.

  1977cited by this paper
• Delayed type hypersensitivity in guinea pigs infected subcutaneously with Naegleria fowleri Carter

  1976cited by this paper
• Differences in destruction of cysts of pathogenic and nonpathogenic Naegleria and Acanthamoeba by chlorine

  1976cited by this paper
• Modification of resistance of mice to Naegleria fowleri infections

  1976cited by this paper
• Primary amoebic mengingoencephalitis contracted in a thermal tributary of the Waikato River--Taupo: a case report.

  1976cited by this paper
• In Vitro Effects of Amphotericin B on Growth and Ultrastructure of the Amoeboflagellates Naegleria gruberi and Naegleria fowleri

  1975cited by this paper
• A strain of pathogenic Naegleria isolated from a human nasal swab.

  1975cited by this paper
• Experimental infections with pathogenic free-living amebae in laboratory primate hosts: I (A) A study on susceptibility to Naegleria fowleri.

  1975cited by this paper
• The 1968 New Zealand cases of primary amoebic meningoencephalitis--Myxomycete or Naegleria?

  1975cited by this paper
• Light and electron microsopic observations on the pathogenesis of Naegleria fowleri in mouse brain and tissue culture.

  1974cited by this paper
• Naegleria: another pathogenic ameba studies in germfree guinea pigs.

  1974cited by this paper
• Myocarditis associated with primary amebic (Naegleria) meningoencephalitis.

  1974cited by this paper
• Hemin replaces serum as a growth requirement for Naegleria.

  1974cited by this paper
• Letter: Primary amoebic meningoencephalitis after swimming in stream water.

  1973cited by this paper
• A METHOD FOR THE ISOLATION OF NAEGLERIA SPECIES FROM WATER SAMPLES

  1973cited by this paper
• Animal model of human disease. Primary amebic meningoencephalitis, Naegleria meningoencephalitis, CNS protozoal infection.

  1973cited by this paper
• Experimental naegleria meningoencephalitis in mice. Penetration of the olfactory mucosal epithelium by Naegleria and pathologic changes produced: a light and electron microscope study.

  1973cited by this paper
• Amebic cellulocutaneous invasion by Naegleria aerobia with generalized visceral lesions after subcutaneous inoculation: an experimental study in guinea pigs.

  1972cited by this paper
• Primary amoebic meningoencephalitis.

  1972cited by this paper
• Acanthamoebiasis in a Dog

  1972cited by this paper
• Primary amoebic meningoencephalitis.

  1972cited by this paper
• [Isolation of amoebae of the type "Hartmannella-Acanthamoeba" and "Naelgeria" from cold-blooded vertebrates].

  1972cited by this paper
• Primary amoebic meningoencephalitis caused by Naegleria. Two new cases, response to amphotericin B, and a review.

  1971cited by this paper
• Ultrastructure of Entamoeba histolytica from human amebic dysentery.

  1971cited by this paper
• Naegleria gruberi: isolation from nasal swab of a healthy individual.

  1971cited by this paper
• Studies on pathogenic and non-pathogenic small free-living amoebae and the bearing of nuclear division on the classification of the order amoebida.

  1970cited by this paper
• Fatal primary amebic meningoencephalitis. A retrospective study in Richmond, Virginia.

  1970cited by this paper
• Amebic meningoencephalitis due to free-living amebas of the Hartmannella (Acanthamoeba)-Naegleria group.

  1968cited by this paper
• Pathogenic Naegleria sp.--study of a strain isolated from human cerebrospinal fluid.

  1968cited by this paper
• An outbreak of acute, fatal amebic meningoencephalitis.

  1968cited by this paper
• Hartmannellosis in a Bull

  1968cited by this paper
• Primary amebic meningoencephalitis.

  1966cited by this paper
• Acute Pyogenic Meningitis Probably Due to Acanthamoeba sp.: a Preliminary Report

  1965cited by this paper

• Assessment of the structure–activity relationship of analogs of the Naegleria fowleri enolase inhibitor HEX

  2025cites this paper
• Understanding Naegleria fowleri : The Risks of Brain Infection

  2025cites this paper
• Optimized Axenic Culture Medium for Comprehensive Biological and Physiological Analysis of Naegleria Fowleri.

  2024cites this paper
• Noninvasive diagnostic biomarkers, genomic profiling, and advanced microscopic imaging in the early detection and characterization of Naegleria fowleri infections leading to primary amebic meningoencephalitis (PAM)

  2024cites this paper
• A Case-Based Review of Free-living Amebic Human Infections and Diagnosis

  2023cites this paper
• Amebic infections of the central nervous system

  2022cites this paper
• Zinc Oxide Nanoconjugates against Brain-Eating Amoebae

  2022cites this paper
• Role of cathepsin B of Naegleria fowleri during primary amebic meningoencephalitis

  2022cites this paper
• Genotyping and Molecular Identification of Acanthamoeba Genotype T4 and Naegleria fowleri from Cerebrospinal Fluid Samples of Patients in Turkey: Is it the Pathogens of Unknown Causes of Death?

  2022cites this paper
• Various brain-eating amoebae: the protozoa, the pathogenesis, and the disease

  2021cites this paper
• Differential Growth Rates and In Vitro Drug Susceptibility to Currently Used Drugs for Multiple Isolates of Naegleria fowleri

  2021cites this paper
• Free Living Amoebas

  2021cites this paper
• Cooperative Evolution: Reclaiming Darwin’s Vision

  2021cites this paper
• Studies on the cyst stage of Naegleria fowleri in vivo and in vitro

  2021cites this paper
• Molecular detection of free-living amoebae from Namhangang (southern Han River) in Korea

  2020cites this paper
• The eukaryome: Diversity and role of microeukaryotic organisms associated with animal hosts

  2020cites this paper
• Environmental abiotic and biotic factors affecting the distribution and abundance of Naegleria fowleri

  2020influential citation
• Epidemiology and Clinical Characteristics of Primary Amebic Meningoencephalitis Caused by Naegleria fowleri: A Global Review.

  2020cites this paper
• Host Invasion by Pathogenic Amoebae: Epithelial Disruption by Parasite Proteins

  2019cites this paper
• Identification of four amoebicidal non-toxic compounds by a molecular docking screen of Naegleria fowleri sterol Δ8-Δ7-isomerase and phenotypic assays.

  2019cites this paper
• IDENTIFICATION OF PEPTIDASES IN HIGHLY-PATHOGENIC VERSUS WEAKLY-PATHOGENIC NAEGLERIA FOWLERI AMEBAE

  2019cites this paper
• Lethal encounters: The evolving spectrum of amoebic meningoencephalitis

  2019cites this paper
• Naegleria fowleri: diagnosis, treatment options and pathogenesis

  2019cites this paper
• The Infectivity of Naegleria fowleri Cysts in vivo and in vitro, and Mediation of Encystment by cAMP

  2019influential citation
• Is Naegleria fowleri an Emerging Parasite?

  2019cites this paper
• Nested PCR assay for the rapid detection of Naegleria fowleri from swimming pools in Egypt

  2018cites this paper
• Expression of matrix metalloproteinases in Naegleria fowleri and their role in invasion of the central nervous system.

  2017cites this paper
• Review: Occurrence of the pathogenic amoeba Naegleria fowleri in groundwater

  2017cites this paper
• Opportunistic Pathogens and the Brain-eating Amoeba, Naegleria fowleri in Reclaimed Water, Municipal Drinking Water, and Private Well Water

  2017influential citation
• Development of a Transfection System for the Free-Living Amoeba Naegleria fowleri Using the piggyBac Vector

  2017cites this paper
• Biology and pathogenesis of Naegleria fowleri.

  2016cites this paper
• Expression, purification, enzymatic characterization and crystallization of glyceraldehyde-3-phosphate dehydrogenase from Naegleria gruberi, the first one from phylum Percolozoa.

  2016cites this paper
• Naegleria fowleri after 50 years: is it a neglected pathogen?

  2016cites this paper
• Detection of Naegleria Isolates from the Egyptian Aquatic Environment

  2015cites this paper
• Comparison of real-time PCR methods for the detection of Naegleria fowleri in surface water and sediment

  2015cites this paper
• Biochemical Criteria of Naegleria Species Isolated from the Egyptian Aquatic Environment

  2015cites this paper
• Identification of Peptidases in Highly Pathogenic vs. Weakly Pathogenic Naegleria fowleri Amebae

  2015cites this paper
• Environmentally Transmitted Pathogens

  2014cites this paper
• Chapter Twenty – Naegleria

  2014cites this paper
• Eukaryotic G Protein Signaling Evolved to Require G Protein–Coupled Receptors for Activation

  2013cites this paper
• Quantitative assessment of Naegleria fowleri and Escherichia coli concentrations within a Texas reservoir.

  2013cites this paper
• STUDENTS' CORNER LETTER TO THE EDITOR

  2013cites this paper
• The paradox of primary amoebic meningoencephalitis--a rare disease, but commonly misdiagnosed.

  2013cites this paper
• Distribution systems as reservoirs of Naegleria fowleri and other amoebae

  2012influential citation
• Molecular, immunological and drug sensitivity studies of pathogenic free-living amoebae

  2012cites this paper
• Induction of interleukin-8 by Naegleria fowleri lysates requires activation of extracellular signal-regulated kinase in human astroglial cells

  2012cites this paper
• Étude des facteurs d'influence de l'écologie de Naegleria fowleri dans les biofilms

  2012cites this paper
• Naegleria fowleri is a water-based protozoan that has been well-documented as a causative agent of primary amoebic menin- goencephalitis, a rapidly progressing disease with a fatality rate

  2012cites this paper
• Photo Quiz. Primary amebic meningoencephalitis.

  2012cites this paper
• Primary Amoebic Meningoencephalitis in an Iranian Infant

  2012cites this paper
• Inactivation of Naegleria Fowleri by chlorine and ultraviolet light

  2012cites this paper
• Environmentally Transmitted Pathogens

  2012cites this paper
• Naegleria fowleri Lysate Induces Strong Cytopathic Effects and Pro-inflammatory Cytokine Release in Rat Microglial Cells

  2011cites this paper
• Multisystemic infection with an Acanthamoeba sp in a dog.

  2011cites this paper
• PROTEOMIC ANALYSIS OF TWO DIFFERENT STATES OF NAEGLERIA FOWLERI

  2011cites this paper
• Demostración del ameboflagelado Naegleria fowleri como agente etiológico de meningoencefalitis amébica

  2011cites this paper
• Development of a rapid DNA extraction method and one-step nested PCR for the detection of Naegleria fowleri from the environment.

  2011influential citation
• A COMPARATIVE STUDY OF A PATHOGENIC VERSUS A NONPATHOGENIC NAEGLERIA SPECIES

  2011influential citation
• Parasitic diseases of the central nervous system.

  2010cites this paper
• The nfa1 Gene Contributed on the Contact-dependent Pathogenic Mechanisms of Naegleria fowleri

  2010cites this paper
• Free-Living Amebas

  2010cites this paper
• Swimming with death: Naegleria fowleri infections in recreational waters.

  2010cites this paper
• Gene silencing of nfa1 affects the in vitro cytotoxicity of Naegleria fowleri in murine macrophages.

  2009cites this paper
• Aislamiento de amebas de vida libre en aguas superficiales del Valle del Mayo, Sonora

  2009cites this paper
• Occurrence of Naegleria fowleri in Arizona drinking water supply wells

  2009influential citation
• In vitro Susceptibility of Naegleria fowleri Trophozoites to Amphotericin B-combined Chlorpromazine

  2009cites this paper
• Pathologic Quiz Case: Headache in an 8-Year-Old Child

  2009cites this paper
• Heat shock protein 70 of Naegleria fowleri is important factor for proliferation and in vitro cytotoxicity

  2008cites this paper
• Occurrence and inactivation of emerging pathogens in the environment

  2008cites this paper
• The role of free-living pathogenic amoeba in the transmission of leprosy: a proof of principle.

  2008cites this paper
• Naegleria fowleri: nfa1 gene knock-down by double-stranded RNAs.

  2008cites this paper
• Production of Nfa1-specific monoclonal antibodies that influences the in vitro cytotoxicity of Naegleria fowleri trophozoites on microglial cells

  2007cites this paper
• ANSWER TO THE PHOTO QUIZ

  2007cites this paper
• Molecular cloning and characterization of a cytosolic heat shock protein 70 from Naegleriafowleri

  2007cites this paper
• Free-living Acanthamoeba and Naegleria spp. amebae in water sources of León, Nicaragua.

  2007cites this paper
• Meningoencephalitis by Naegleria fowleri: epidemiological study in Anzoategui state, Venezuela.

  2006cites this paper
• The immunology of parasite infections in immunocompromised hosts

  2006cites this paper
• Knockdown of nfa1 Gene Cloned from Naegleria fowleri by Antisense RNA

  2006cites this paper
• Naegleria fowleri: functional expression of the Nfa1 protein in transfected Naegleria gruberi by promoter modification.

  2006cites this paper
• Expression of the nfa1 Gene Cloned from Pathogenic Naegleria fowleri in Nonpathogenic N. gruberi Enhances Cytotoxicity against CHO Target Cells In Vitro

  2005cites this paper
• Vitro Cytotoxicity against CHO Target Cells In Enhances N . gruberi Nonpathogenic in Naegleria fowleri Pathogenic Gene Cloned from nfa 1 Expression of the

  2005cites this paper
• Amphizoic amoebae: pathogenic free-living protozoa; review of the literature and review of cases in Thailand.

  2005cites this paper
• Cytopathic changes and pro‐inflammatory cytokines induced by Naegleria fowleri trophozoites in rat microglial cells and protective effects of an anti‐Nfa1 antibody

  2005cites this paper
• Granulomatous Diseases of the Central Nervous System

  2005cites this paper
• Fatal case of Naegleria fowleri meningo-encephalitis in an infant: case report

  2005cites this paper
• Seasonal Meningoencephalitis in Holstein Cattle Caused by Naegleria Fowleri

  2005cites this paper
• Role of the Nfa1 Protein in Pathogenic Naegleria fowleri Cocultured with CHO Target Cells

  2005cites this paper
• Cytopathogenicity ofNaegleria fowleri in mammalian cell cultures

  2004cites this paper
• Light and electron microscope observation of virus-induced Tetrahymena pyriformis in newborn mice (Mus musculus albinicus) brain

  2004cites this paper
• Decreasing effect of an anti-Nfa1 polyclonal antibody on the in vitro cytotoxicity of pathogenic Naegleria fowleri.

  2004cites this paper
• Pathologic quiz case: headache in an 8-year-old child. Primary amebic meningoencephalitis due to Naegleria fowleri.

  2004cites this paper
• Cloning and characterization of an immunoreactive gene encoding a calcium-binding protein from Naegleria fowleri.

  2004cites this paper
• 22 – Naegleria fowleri

  2004cites this paper
• CHAPTER 5 Free-living microorganisms

  2003cites this paper
• Genetic Variations in the Internal Transcribed Spacer and Mitochondrial Small Subunit rRNA Gene of Naegleria spp

  2003cites this paper
• Genetic Variations in the Internal Transcribed Spacer and Mitochondrial Small Subunit rRNA Gene of Naegleria spp.

  2003cites this paper
• Cultivation of Pathogenic and Opportunistic Free-Living Amebas

  2002cites this paper
• Pore-forming Polypeptides of the Pathogenic Protozoon Naegleria fowleri *

  2002cites this paper
• Naegleria meningitis: a rare survival.

  2002cites this paper
• Rapid Detection and Enumeration of Naegleria fowleri in Surface Waters by Solid-Phase Cytometry

  2002cites this paper