Human Erythrocyte Glycosphingolipids as Alternative Cofactors for Human Immunodeficiency Virus Type 1 (HIV-1) Entry: Evidence for CD4-Induced Interactions between HIV-1 gp120 and Reconstituted Membrane Microdomains of Glycosphingolipids (Gb3 and GM3)

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Journal of Virology

• Publication date

  1999-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/JVI.73.6.5244-5248.1999PMID 10233996PMCID PMC112578
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A new classification for HIV-1

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• Specific Interaction of HIV-1 and HIV-2 Surface Envelope Glycoproteins with Monolayers of Galactosylceramide and Ganglioside GM3*

  1998influential reference
• Human erythrocyte glycolipids promote HIV-1 envelope glycoprotein-mediated fusion of CD4+ cells.

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• Sequential interaction of CD4 and HIV-1 gp120 with a reconstituted membrane patch of ganglioside GM3: implications for the role of glycolipids as potential HIV-1 fusion cofactors.

  1998influential reference
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• HIV-1-induced perturbations of glycosphingolipid metabolism are cell-specific and can be detected at early stages of HIV-1 infection.

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• HIV-cell fusion. The viral mousetrap.

  1997cited by this paper
• The viral mousetrap

  1997influential reference
• Evidence for the existence of ganglioside-enriched plasma membrane domains in human peripheral lymphocytes.

  1997cited by this paper
• Functional rafts in cell membranes

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