Gut hormone PYY3-36 physiologically inhibits food intake

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Nature

• Publication date

  2002-08-08

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1038/nature00887PMID 12167864
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The mouse brain in stereotaxic coordinates

  2003cited by this paper
• The Mouse Brain in Stereotaxic Coordinates

  2001cited by this paper
• Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

  2001cited by this paper
• Exendin-4 reduces fasting and postprandial glucose and decreases energy intake in healthy volunteers.

  2001cited by this paper
• Melanocortin-4 receptor is required for acute homeostatic responses to increased dietary fat

  2001cited by this paper
• Neuropeptide Y Y5 receptor protein in the cortical/limbic system and brainstem of the rat: expression on gamma-aminobutyric acid and corticotropin-releasing hormone neurons.

  2000cited by this paper
• The central melanocortin system affects the hypothalamo-pituitary thyroid axis and may mediate the effect of leptin.

  2000cited by this paper
• Primary structures of PYY, [Pro(34)]PYY, and PYY-(3-36) confer different conformations and receptor selectivity.

  2000cited by this paper
• Genetics of body-weight regulation

  2000cited by this paper
• Central nervous system control of food intake

  2000cited by this paper
• Cholecystokinin and satiety: current perspectives.

  2000cited by this paper
• Association of Human Immunodeficiency Virus Type 1 Vif with RNA and Its Role in Reverse Transcription

  2000cited by this paper
• Human Immunodeficiency Virus Type 1 Vif Protein Is an Integral Component of an mRNP Complex of Viral RNA and Could Be Involved in the Viral RNA Folding and Packaging Process

  2000cited by this paper
• Hypothalamic localization of the feeding effect of agouti-related peptide and alpha-melanocyte-stimulating hormone.

  2000cited by this paper
• Zebrafish Genes for Neuropeptide Y and Peptide YY Reveal Origin by Chromosome Duplication from an Ancestral Gene Linked to the Homeobox Cluster

  2000cited by this paper
• Interacting appetite-regulating pathways in the hypothalamic regulation of body weight.

  1999cited by this paper
• Evidence for a newly discovered cellular anti-HIV-1 phenotype

  1998cited by this paper
• Leptin-induced decrease in food intake is not associated with changes in gastric emptying in lean mice.

  1997cited by this paper
• Peptide analogue studies of the hypothalamic neuropeptide Y receptor mediating pituitary adrenocorticotrophic hormone release.

  1997cited by this paper
• HIV‐1 infection of non‐dividing cells: evidence that the amino‐terminal basic region of the viral matrix protein is important for Gag processing but not for post‐entry nuclear import

  1997cited by this paper
• Subtypes Y1 and Y2 of the neuropeptide Y receptor are respectively expressed in pro-opiomelanocortin- and neuropeptide-Y-containing neurons of the rat hypothalamic arcuate nucleus.

  1997cited by this paper
• A model of gastric emptying using paracetamol absorption in intensive care patients

  1997cited by this paper
• Activation of the ubiquitin pathway in rat skeletal muscle by catabolic doses of glucocorticoids.

  1997cited by this paper
• Influence of meal composition on postprandial peripheral plasma concentrations of vasoactive peptides in man.

  1996cited by this paper
• The human immunodeficiency virus type 1 Vif protein modulates the postpenetration stability of viral nucleoprotein complexes

  1996cited by this paper
• Human immunodeficiency virus type 1 Vif does not influence expression or virion incorporation of gag-, pol-, and env-encoded proteins

  1996cited by this paper
• The reproducibility of subjective appetite scores

  1995cited by this paper
• A novel neuropeptide Y analog, N-acetyl [Leu28,Leu31]neuropeptide Y-(24-36), with functional specificity for the presynaptic (Y2) receptor.

  1994cited by this paper
• Mutations affecting transition-state stabilization by residues coordinating zinc at the active site of cytidine deaminase.

  1994cited by this paper
• Two molecular forms of peptide YY (PYY) are abundant in human blood: characterization of a radioimmunoassay recognizing PYY 1-36 and PYY 3-36.

  1994cited by this paper
• Molecular cloning of an apolipoprotein B messenger RNA editing protein.

  1993cited by this paper
• c-Fos and related immediate early gene products as markers of activity in neuroendocrine systems.

  1993cited by this paper
• Efficiency of viral DNA synthesis during infection of permissive and nonpermissive cells with vif-negative human immunodeficiency virus type 1

  1993cited by this paper
• Fv-1 restriction and its effects on murine leukemia virus integration in vivo and in vitro

  1992cited by this paper
• Human distribution and release of a putative new gut hormone, peptide YY.

  1985cited by this paper

• Evaluation of the Relationship Between Orexin A, Peptide YY, AgRP, and POMC Levels and Sleep Disorders in Children with Malnutrition

  2026cites this paper
• Significance of neuroendocrine systems and the gut-brain axis (GBA) in the regulation of obesity

  2026cites this paper
• Orexinergic responses to environmental stressors in the zebrafish gut.

  2026cites this paper
• Glucagon-like peptide-1–based pharmacological treatment of obesity: a narrative review

  2026cites this paper
• NPY2R Agonist-Induced Gastric Effects Leading to Intestinal Dysbiosis and Secondary Intestinal Pathology in CD1 Mice

  2026cites this paper
• Emerging incretin- and multi-agonist-based treatments - the continued refinement and continuous expansion of a potent therapeutic armamentarium for cardio-kidney-liver-metabolic diseases and beyond.

  2026cites this paper
• Low Small Intestinal PYY Immunoreactive Cell Density and PYY Gene Expression in Patients With Familial GUCY2C Diarrhea Syndrome.

  2026cites this paper
• Impact of Palliative Gastrojejunostomy Type on Survival in Patients with Unresectable Pancreatic Head Cancer: A Retrospective Analysis.

  2026cites this paper
• Gut-brain axis in health and brain disease.

  2026cites this paper
• Migrant blackbirds (Turdus merula) on stopover have higher plasma PYY compared to residents: A validation and proof-of-concept.

  2026cites this paper
• Metabolic and pathophysiological characterization of constitutional thinness.

  2026cites this paper
• The role of PYY in improving insulin resistance.

  2026cites this paper
• “Rewiring the hypothalamus: emerging neuroendocrine and neurotechnological approaches to obesity”

  2026cites this paper
• Dietary strategies for chronic constipation: smartly targeting hormonal and reflex pathways for optimal recovery.

  2026cites this paper
• Advances and future directions in endoscopic bariatric therapies

  2025cites this paper
• Neuropeptide Y receptors in GtoPdb v.2025.3

  2025cites this paper
• Metabolic and appetitive regulation of adipocyte mass during treatment of obesity

  2025cites this paper
• A Signaling Hub in the Mosquito Rectum Coordinates Reproductive Investment After Blood Feeding

  2025cites this paper
• Brain amino acid sensing for organismal amino acid homeostasis

  2025cites this paper
• Development of a potent Xenopus GLP-1-derived GLP-1/GIP/Y2 receptor tri-agonist for obesity and type 2 diabetes.

  2025cites this paper
• Neuroendocrine control of glucose homeostasis: integrative mechanisms from the hypothalamus to the brainstem

  2025cites this paper
• The central signaling pathways related to metabolism-regulating hormones of the gut-brain axis: a review

  2025cites this paper
• UCP2 mediates mitochondrial dynamics to induce AgRP neuronal activity

  2025cites this paper
• The mixed-meal tolerance test as an appetite assay: methodological and practical considerations

  2025cites this paper
• Impacts of Bacillus-based biotics and an enzyme cocktail on growth performance, immunity, and gut pathogenic microorganisms of nursery pigs under commercial conditions

  2025cites this paper
• Characteristics of Polyphenols of Black Hulless Barley Bran and Its Anti-Diabetic Activity

  2025cites this paper
• Transient ligand contacts of the intrinsically disordered N-terminus of neuropeptide Y2 receptor regulate arrestin-3 recruitment

  2025cites this paper
• Pre-stroke weight loss by glucagon-like peptide 1 receptor and neuropeptide Y receptor Y2 activation improves post-stroke functional recovery in male diabetic mouse models

  2025cites this paper
• Overeating: A Conundrum of Lipid Metabolism and Inflammation in Obesity and Cancer

  2025influential citation
• The effect of consuming different dietary protein sources at breakfast upon self rated satiety, peptide YY, glucagon like peptide-1, and subsequent food intake in young and older adults

  2025cites this paper
• Neuroendocrinology and Genetics of Obesity.

  2025cites this paper
• The metabolic and cardiovascular effects of amphetamine are partially mediated by the central melanocortin system

  2025cites this paper
• PYY-mediated appetite control and obesity alleviation through short-chain fatty acid-driven gut-brain axis modulation by Lacticaseibacillus rhamnosus HF01 isolated from Qula.

  2025cites this paper
• Molecular Design of Unimolecular Tetra-Receptor Agonists.

  2025cites this paper
• Sequential Meals Containing Animal and Plant-Based Saturated Fats Have Differential Effects on Postprandial Gut Hormones but No Impact on Satiety Compared with Unsaturated Fats in Generally Healthy Males: Findings from the Randomized Controlled Crossover CocoHeart Study

  2025cites this paper
• Paraben exposures and satiety hormones in preschool children: an ENVIRONAGE study

  2025cites this paper
• A gut sense for a microbial pattern regulates feeding

  2025cites this paper
• Synaptic and intrinsic plasticity mediated by CCK-type signaling coordinates behavioral changes during motivational state shifts

  2025cites this paper
• The protective role of PYY in intestinal mucosal defects induced by SATB2 deficiency in inflammatory bowel disease

  2025cites this paper
• Appetite-related Gut Hormone Responses to Feeding Across the Life Course

  2025cites this paper
• Side-Stream Based Marine Solubles From Atlantic Cod (Gadus morhua) Modulate Appetite and Dietary Nutrient Utilization in Atlantic Salmon (Salmo salar L.) and can Replace Fish Meal

  2025cites this paper
• Rational design of dual-agonist peptides targeting GLP-1 and NPY2 receptors for regulating glucose homeostasis and body weight with minimal nausea and emesis.

  2025cites this paper
• A cellular basis for heightened gut sensitivity in females.

  2025cites this paper
• Monascus pilosus SWM‐008–Fermented Red Mold Rice and Its Monascinol Ameliorate Non‐Alcoholic Fatty Liver Disease via Activation of the AMPK–ATGL Pathway and Enrichment of Butyrate‐Producing Bacteria

  2025cites this paper
• Advancing obesity treatments through innovations in the design and manufacturing of therapeutic peptides

  2025cites this paper
• From Gut to Brain: The Roles of Intestinal Microbiota, Immune System, and Hormones in Intestinal Physiology and Gut-Brain-Axis.

  2025cites this paper
• Butyric acid ameliorates PCOS-related reproductive dysfunction through gut-brain-ovary axis signaling and ovarian steroidogenic factor activation

  2025cites this paper
• Gut Microbiota in Women with Eating Disorders: A New Frontier in Pathophysiology and Treatment

  2025cites this paper
• Slow starch digestibility promotes the development of favorable feeding behaviors and metabolic health in mice.

  2025cites this paper
• A 3-Week Inpatient Rehabilitation Programme Improves Body Composition in People with Cystic Fibrosis with and Without Elexacaftor/Tezacaftor/Ivacaftor Therapy

  2025cites this paper
• Effects of Central Administration of Opioid Peptides, Vasotocin, Mesotocin, and Corticotrophin-Releasing Factor on Water Intake in Chicks

  2025cites this paper
• The Effect of Probiotics on the Improvement of Body Weight and Fat

  2025cites this paper
• Sample storage and fasting times affect blood serum and plasma components in fasted and non-fasted broiler chickens

  2025cites this paper
• The Pathogenesis and Medical Treatment of Depression: Opportunity and Challenge

  2025cites this paper
• Mechanisms through which laparoscopic sleeve gastrectomy mitigates atherosclerosis risk: a focus on visceral adipose tissue

  2025cites this paper
• Impact of Varied Dietary Macronutrient Ratios on the Nutrition Status of Swiss Albino Mice

  2025cites this paper
• Hormonal Alterations in Individuals with Obesity After Metabolic Bariatric Surgery: A Narrative Review

  2025cites this paper
• Novel GLP-1-Based Medications for Type 2 Diabetes and Obesity.

  2025cites this paper
• Variant screening of PYY3-36 leads to potent long-acting PYY analogs with superior Y2 receptor selectivity.

  2025cites this paper
• Divergence and conservation of neuropeptide Y receptors in teleosts with diverse feeding habits.

  2025cites this paper
• Impact of dietary fiber on PCOS: a systematic review

  2025cites this paper
• Peptide YY in Type 2 Diabetes: A Complementary Gut Hormone with Therapeutic Potential Beyond GLP-1

  2025cites this paper
• Investigating fecal microbiota transplants from individuals with anorexia nervosa in antibiotic-treated mice using a cross-over study design

  2025cites this paper
• Novel pharmacotherapies for weight loss: Understanding the role of incretins to enable weight loss and improved health outcomes

  2025cites this paper
• The free fatty acid receptor 2 (FFA2): Mechanisms of action, biased signaling, and clinical prospects.

  2025cites this paper
• Isoenergetic reduction of dietary macronutrients affects body composition, physical activity, and post-prandial hormone responses in lean and obese cats fed to maintain body weight

  2025cites this paper
• Physical activity promotes gut adaptation, responses to nutrients, and sensitivity to gut peptides

  2025cites this paper
• Evaluating methodological constraints in PET imaging of neuropeptide Y2 receptors with N-[11C]-methyl-(R)-JNJ-31020028 in brains of C57BL/6J mice

  2025cites this paper
• A Cellular Basis for Heightened Gut Sensitivity in Females

  2025cites this paper
• Study on the efficacy and mechanism of resistant dextrin combined with mulberry leaf extract in ameliorating type 2 diabetes mellitus.

  2025cites this paper
• Long‐acting PYY3 −36 analogue with semaglutide for obesity: from preclinical assessment through randomized clinical studies

  2025cites this paper
• The role of GIPR in food intake control

  2025cites this paper
• Endogenous hydrogen peroxide positively regulates secretion of a gut-derived peptide in neuroendocrine potentiation of the oxidative stress response in Caenorhabditis elegans

  2024cites this paper
• Photochemically-enabled, post-translational production of C-terminal amides

  2024influential citation
• What to expect in the first 3 months following a sleeve gastrectomy?

  2024cites this paper
• The effects of gut microbiota on appetite regulation and the underlying mechanisms

  2024cites this paper
• pH Controlled transient cyclization of peptides for increased stability towards oral delivery.

  2024cites this paper
• The emerging role of gut hormones

  2024cites this paper
• Intestinal-level anti-inflammatory bioactivities of whole wheat: Rationale, design, and methods of a randomized, controlled, crossover dietary trial in adults with prediabetes.

  2024cites this paper
• Stapled peptides as potential therapeutics for diabetes and other metabolic diseases.

  2024cites this paper
• A review: Anti-obesity drug discovery from natural plant metabolites and endogenous peptides

  2024cites this paper
• Dapagliflozin, peptide YY, and weight loss in heart failure with preserved ejection fraction.

  2024cites this paper
• A homeostatic gut-to-brain insulin antagonist restrains neuronally stimulated fat loss

  2024cites this paper
• Endogenous hydrogen peroxide positively regulates secretion of a gut-derived peptide in neuroendocrine potentiation of the oxidative stress response in C. elegans

  2024cites this paper
• The role of nutrient sensing dysregulation in anorexia of ageing: The little we know and the much we don't.

  2024cites this paper
• Hidden: A Baker’s Dozen Ways in Which Research Reporting is Less Transparent than it Could be and Suggestions for Implementing Einstein’s Dictum

  2024cites this paper
• [P3]PP, a stable, long‐acting pancreatic polypeptide analogue, evokes weight lowering and pancreatic beta‐cell‐protective effects in obesity‐associated diabetes

  2024cites this paper
• Enteroendocrine Cells Regulate Intestinal Homeostasis and Epithelial Function.

  2024cites this paper
• Neo-Glycolipid Oximes as Intestinal Permeation Enhancers for Peptide Hormone PYY3-36.

  2024cites this paper
• Effect of LED spectrum on the vision, appetite, and growth of red seabream (Pagrus major)

  2024cites this paper
• Microfluidic chips in female reproduction: a systematic review of status, advances, and challenges

  2024cites this paper
• THE ADIPOSE TISSUE MELANOCORTIN 3 RECEPTOR IS TARGETED BY GHRELIN AND LEPTIN AND MAY BE A THERAPEUTIC TARGET IN OBESITY.

  2024influential citation
• PERAN KANDUNGAN ZAT GIZI DAN SENYAWA BIOAKTIF PISANG TERHADAP TINGKAT NAFSU MAKAN : A LITERATURE REVIEW

  2024cites this paper
• Hypothalamic AgRP neurons regulate the hyperphagia of lactation

  2024cites this paper
• Lipid-encapsulated mRNA encoding an extended serum half-life interleukin-22 ameliorates metabolic disease in mice

  2024cites this paper
• Serum levels of leptin, ghrelin putative peptide YY-3 in patients with fetal alcohol spectrum disorders

  2024cites this paper
• NPYR modulation: Potential for the next major advance in obesity and type 2 diabetes management?

  2024influential citation
• Stronger control of eating 3 months after sleeve gastrectomy predicts successful weight loss outcomes at one year

  2024cites this paper
• Amylin‐like immunoreactivity in the extra‐islet peptide YY‐producing and glucagon‐immunoreactive cells in Japanese quail pancreas

  2024cites this paper
• Novel Pharmaceuticals in Appetite Regulation: Exploring emerging gut peptides and their pharmacological prospects

  2024cites this paper